Quality of life measures in health care. I: Applications and issues in assessment.

abstract：:The Health of the Nation white paper set a target for 15% reduction in overall suicide rates by the year 2000. If the targets are to be achieved interventions must be identified which are of proved effectiveness. This paper examines the evidence on the available interventions and points of access to the population at ...

journal_title：BMJ (Clinical research ed.)

authors： Gunnell D,Frankel S

更新日期：1994-05-07 00:00:00

abstract：OBJECTIVES:To assess whether blood pressure control in primary care could be improved with the use of patient held targets and self monitoring in a practice setting, and to assess the impact of these on health behaviours, anxiety, prescribed antihypertensive drugs, patients' preferences, and costs. DESIGN:Randomised c...

journal_title：BMJ (Clinical research ed.)

authors： McManus RJ,Mant J,Roalfe A,Oakes RA,Bryan S,Pattison HM,Hobbs FD

更新日期：2005-09-03 00:00:00

abstract：:Medical audit has its critics, who point to the large sums of NHS cash that seem to be disappearing down a medical plughole. These criticisms are recognised by medical audit advisory groups but there are many reasons why the work of these groups has not yet resulted in many publications in journals or bumped up health...

journal_title：BMJ (Clinical research ed.)

authors： Johnson R

更新日期：1994-07-09 00:00:00

abstract：:Organs for donation are in short supply in the United Kingdom, resulting in allegations that relatives of potential donors are not being asked for consent. Legislation on "required request" has been proposed to overcome this. The incidence, causes, complications, and patterns of organ donation in brain stem dead patie...

journal_title：BMJ (Clinical research ed.)

authors： Bodenham A,Berridge JC,Park GR

更新日期：1989-10-21 00:00:00

abstract：OBJECTIVE:To evaluate whether follow up of patients with inflammatory bowel disease is better through open access than by routine booked appointments. DESIGN:Pragmatic randomised controlled trial. SETTING:Two district general hospitals in Swansea and Neath, Wales. PARTICIPANTS:180 adults (78 with Crohn's disease, 77...

journal_title：BMJ (Clinical research ed.)

authors： Williams JG,Cheung WY,Russell IT,Cohen DR,Longo M,Lervy B

更新日期：2000-02-26 00:00:00

abstract：OBJECTIVE:To examine the effect of the method of data display on physician investigators' decisions to stop hypothetical clinical trials for an unplanned statistical analysis. DESIGN:Prospective, mixed model design with variables between subjects and within subjects (repeated measures). SETTING:Comprehensive cancer c...

journal_title：BMJ (Clinical research ed.)

authors： Elting LS,Martin CG,Cantor SB,Rubenstein EB

更新日期：1999-06-05 00:00:00

abstract：:Physicians need to evaluate clinical research critically, and determining the power of a study is an essential component of research evaluation. This report presents a graphical aid that permits rapid power determination for clinical trials with two groups. Power curves were developed for dichotomous outcomes by setti...

journal_title：BMJ (Clinical research ed.)

authors： Miller DK,Homan SM

更新日期：1988-09-10 00:00:00

abstract：OBJECTIVES:To examine the effects of physical work environment on long term sickness absence and to investigate interaction between physical and psychosocial risk factors. DESIGN AND SETTING:Prospective cohort study of long term sickness absence among employees in Denmark. PARTICIPANTS:5357 employees interviewed in 2...

journal_title：BMJ (Clinical research ed.)

authors： Lund T,Labriola M,Christensen KB,Bültmann U,Villadsen E

更新日期：2006-02-25 00:00:00

abstract：OBJECTIVE:To systematically evaluate the published evidence regarding the characteristics and effectiveness of disease management programmes. DESIGN:Meta-analysis. DATA SOURCES:Computerised databases for English language articles during 1987-2001. STUDY SELECTION:102 articles evaluating 118 disease management progra...

journal_title：BMJ (Clinical research ed.)

authors： Weingarten SR,Henning JM,Badamgarav E,Knight K,Hasselblad V,Gano A Jr,Ofman JJ

更新日期：2002-10-26 00:00:00

abstract：OBJECTIVE:To estimate the usefulness of serum concentrations of the complex of trypsin 2 and alpha 1 antitrypsin in diagnosing and assessing the severity of acute pancreatitis in comparison with serum C reactive protein, amylase, and trypsinogen 2 concentrations (reference markers). DESIGN:Markers were measured in con...

journal_title：BMJ (Clinical research ed.)

authors： Hedström J,Sainio V,Kemppainen E,Haapiainen R,Kivilaakso E,Schröder T,Leinonen J,Stenman UH

更新日期：1996-08-10 00:00:00

abstract：OBJECTIVE:To compare the functional results after displaced fractures of the femoral neck treated with internal fixation or hemiarthroplasty. DESIGN:Randomised trial with blinding of assessments of functional results. SETTING:University hospital. PARTICIPANTS:222 patients; 165 (74%) women, mean age 83 years. Inclusi...

journal_title：BMJ (Clinical research ed.)

authors： Frihagen F,Nordsletten L,Madsen JE

更新日期：2007-12-15 00:00:00

abstract：:The World Health Organization's (WHO) definition of health as "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity" had the merit of widening concepts of health to include psychological and social aspects, but is of no practical use. In fact, this statement m...

journal_title：BMJ (Clinical research ed.)

authors： Saracci R

更新日期：1997-05-10 00:00:00

abstract：OBJECTIVE:To quantify the impact of citalopram and other selective serotonin reuptake inhibitors on corrected QT interval (QTc), a marker of risk for ventricular arrhythmia, in a large and diverse clinical population. DESIGN:A cross sectional study using electrocardiographic, prescribing, and clinical data from electr...

journal_title：BMJ (Clinical research ed.)

authors： Castro VM,Clements CC,Murphy SN,Gainer VS,Fava M,Weilburg JB,Erb JL,Churchill SE,Kohane IS,Iosifescu DV,Smoller JW,Perlis RH

更新日期：2013-01-29 00:00:00

abstract：OBJECTIVES:To compile a register of diabetic patients within the catchment area of a district general hospital and evaluate the characteristics of the population using aggregated data from a general practice audit. DESIGN:Cross sectional study. Practices identified all known diabetics and completed a questionnaire fro...

journal_title：BMJ (Clinical research ed.)

authors： Howitt AJ,Cheales NA

更新日期：1993-10-23 00:00:00

abstract：OBJECTIVE:To determine the effectiveness of interventions designed to improve outcomes in patients with multimorbidity in primary care and community settings. DESIGN:Systematic review. DATA SOURCES:Medline, Embase, CINAHL, CAB Health, Cochrane central register of controlled trials, the database of abstracts of review...

journal_title：BMJ (Clinical research ed.)

authors： Smith SM,Soubhi H,Fortin M,Hudon C,O'Dowd T

更新日期：2012-09-03 00:00:00

abstract：OBJECTIVE:To determine if any excess of childhood leukaemia was associated with the large and increasing numbers of national military servicemen in 1949 and 1950, particularly in rural districts. This would be a further test of the hypothesis that childhood leukaemia can originate in an infection, the transmission of w...

journal_title：BMJ (Clinical research ed.)

authors： Kinlen LJ,Hudson C

更新日期：1991-11-30 00:00:00

abstract：OBJECTIVES:To determine the accuracy of a clinical decision rule (the traffic light system developed by the National Institute for Health and Clinical Excellence (NICE)) for detecting three common serious bacterial infections (urinary tract infection, pneumonia, and bacteraemia) in young febrile children. DESIGN:Retro...

journal_title：BMJ (Clinical research ed.)

authors： De S,Williams GJ,Hayen A,Macaskill P,McCaskill M,Isaacs D,Craig JC

更新日期：2013-02-13 00:00:00

abstract：OBJECTIVE:To encourage active participation of Leicestershire general practitioners and their staff in audit; to examine the use of vitamin B-12 injections and to achieve a more appropriate use. DESIGN:Implementation of an agreed audit protocol, with central analysis and feedback of anonymous and aggregated data by a ...

journal_title：BMJ (Clinical research ed.)

authors： Fraser RC,Farooqi A,Sorrie R

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:To describe the characteristics at birth of children conceived by in vitro fertilisation (IVF) or by gamete intrafallopian transfer (GIFT) and to assess whether they differ from those of children conceived naturally. DESIGN:Survey of children resulting from IVF or GIFT and comparison of their characteristics...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1990-05-12 00:00:00

abstract：OBJECTIVE:To investigate estimation of calorie (energy) content of meals from fast food restaurants in adults, adolescents, and school age children. DESIGN:Cross sectional study of repeated visits to fast food restaurant chains. SETTING:89 fast food restaurants in four cities in New England, United States: McDonald's...

journal_title：BMJ (Clinical research ed.)

authors： Block JP,Condon SK,Kleinman K,Mullen J,Linakis S,Rifas-Shiman S,Gillman MW

更新日期：2013-05-23 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of parenteral corticosteroids for the relief of acute severe migraine headache and prevention of recurrent headaches. DESIGN:Meta-analysis. DATA SOURCES:Electronic databases (Cochrane Central Register of Controlled Trials, Medline, Embase, LILACS, and CINAHL), conference proceed...

journal_title：BMJ (Clinical research ed.)

authors： Colman I,Friedman BW,Brown MD,Innes GD,Grafstein E,Roberts TE,Rowe BH

更新日期：2008-06-14 00:00:00

abstract：:The results of a survey of 769 patients attending the St. James's University Fertility Control Clinic, England, for abortion services showed that patients seeing general practitioners were less knowledgeable than those attending specialist clinics. There was a demonstrated need for counseling on pill and condom use a...

journal_title：BMJ (Clinical research ed.)

authors： Bromham DR,Cartmill RS

更新日期：1993-02-27 00:00:00

abstract：OBJECTIVE:To assess the association between genitourinary infections in the month before conception to the end of the first trimesterand gastroschisis. DESIGN:Case-control study with self reported infections from a computer assisted telephone interview. SETTING:National birth defects prevention study, a multisite, po...

journal_title：BMJ (Clinical research ed.)

authors： Feldkamp ML,Reefhuis J,Kucik J,Krikov S,Wilson A,Moore CA,Carey JC,Botto LD

更新日期：2008-06-21 00:00:00

abstract：OBJECTIVE:To assess whether sleep apnoea syndrome is an independent risk factor for hypertension. DESIGN:Population study. SETTING:Sleep clinic in Toronto. PARTICIPANTS:2,677 adults, aged 20-85 years, referred to the sleep clinic with suspected sleep apnoea syndrome. OUTCOME MEASURES:Medical history, demographic da...

journal_title：BMJ (Clinical research ed.)

authors： Lavie P,Herer P,Hoffstein V

更新日期：2000-02-19 00:00:00

abstract：:Eleven euthyroid patients with severe Graves' eye disease were treated with intravenous methylprednisolone and followed up for six months or more by ophthalmological assessment, orbital computed tomography (CT), photographs, and antibody measurements. Papilloedema resolved in the single patient in whom it was present;...

journal_title：BMJ (Clinical research ed.)

authors： Kendall-Taylor P,Crombie AL,Stephenson AM,Hardwick M,Hall K

更新日期：1988-12-17 00:00:00

abstract：OBJECTIVE:To determine, using research on duloxetine for major depressive disorder as an example, if there are inconsistencies between protocols, clinical study reports, and main publicly available sources (journal articles and trial registries), and within clinical study reports themselves, with respect to benefits an...

journal_title：BMJ (Clinical research ed.)

authors： Maund E,Tendal B,Hróbjartsson A,Jørgensen KJ,Lundh A,Schroll J,Gøtzsche PC

更新日期：2014-06-04 00:00:00

abstract：:Environmental issues tend to greater political attention than do environmental health aspects. Therefore, when conflicts of interest occur with other environmental concerns, negative consequences for public health may result. For example, a strategy to substantially reduce indoor ventilation in many dwellings in Sca...

journal_title：BMJ (Clinical research ed.)

authors： Pershagen G

更新日期：1999-06-19 00:00:00

abstract：OBJECTIVE: To evaluate the effectiveness of antenatal corticosteroids given at ≥34 weeks' gestation. DESIGN: Systematic review with meta-analysis. DATA SOURCES: Electronic databases were searched from their inception to February 2016. ELIGIBILITY CRITERIA FOR STUDY SELECTION: Randomized clinical trials comparing ant...

journal_title：BMJ (Clinical research ed.)

authors： Saccone G,Berghella V

更新日期：2016-10-12 00:00:00

abstract：OBJECTIVE:To prepare and assess the sensitivity and specificity of a latex agglutination test specific for the serotype of antigen in diagnosing pneumococcal pneumonia in Gambian children. DESIGN:Comparison of agglutination test specific for serotype with culture of blood and lung aspirates, countercurrent immunoelect...

journal_title：BMJ (Clinical research ed.)

authors： O'Neill KP,Lloyd-Evans N,Campbell H,Forgie IM,Sabally S,Greenwood BM

更新日期：1989-04-22 00:00:00

abstract：:The first call for applications to the NHS research and development programme on the interface between primary and secondary care was advertised in February 1994. A total of 674 outline proposals were submitted and 54 (8%) secured funding. Projects have been commissioned in 16 of the 21 priority areas and around 6m po...

journal_title：BMJ (Clinical research ed.)

authors： Wisely J,Haines A

更新日期：1995-10-21 00:00:00