Graphical aid for determining power of clinical trials involving two groups.

abstract：OBJECTIVE:To examine how the relaxation of the one child policy and policies to reduce caesarean section rates might have affected trends over time in caesarean section rates and perinatal and pregnancy related mortality in China. DESIGN:Observational study. SETTING:China's National Maternal Near Miss Surveillance Sy...

journal_title：BMJ (Clinical research ed.)

authors： Liang J,Mu Y,Li X,Tang W,Wang Y,Liu Z,Huang X,Scherpbier RW,Guo S,Li M,Dai L,Deng K,Deng C,Li Q,Kang L,Zhu J,Ronsmans C

更新日期：2018-03-05 00:00:00

abstract：OBJECTIVES:To determine whether informed consent introduces selection bias in prospective observational studies using data from medical records, and consent rates for such studies. DESIGN:Systematic review. DATA SOURCES:Embase, Medline, and the Cochrane Library up to March 2008, reference lists from pertinent article...

journal_title：BMJ (Clinical research ed.)

authors： Kho ME,Duffett M,Willison DJ,Cook DJ,Brouwers MC

更新日期：2009-03-12 00:00:00

abstract：:A brief note on the status of the AIDS pandemic, from the Amsterdam VIIIth International Conference on AIDS, warns that the course of the epidemic is not being altered by prevention efforts. AIDS occurs in every country, usually spread by heterosexual contact, so that women are equally affected with men. WHO estimat...

journal_title：BMJ (Clinical research ed.)

authors： Tanne JH

更新日期：1992-07-25 00:00:00

abstract：:Telephone helplines are an effective way of dealing with health related incidents in which large numbers of people need personal counselling or information for reassurance or case finding. Helplines often have to be set up at short notice, which is labour intensive and makes recruitment of appropriate staff difficult....

journal_title：BMJ (Clinical research ed.)

authors： Stark C,Christie P,Marr AC

更新日期：1994-07-02 00:00:00

abstract：OBJECTIVES:To investigate the possible influence of attendance at cultural events, reading books or periodicals, making music or singing in a choir as determinants for survival. DESIGN:A simple random sample was drawn of 15,198 individuals aged 16-74 years. Of these, 85% (12,982) were interviewed by trained non-medica...

journal_title：BMJ (Clinical research ed.)

authors： Bygren LO,Konlaan BB,Johansson SE

更新日期：1996-12-21 00:00:00

abstract：:Cancers of unknown primary (CUPs) are histologically confirmed, metastatic malignancies with a primary tumor site that is unidentifiable on the basis of standard evaluation and imaging studies. CUP comprises 2-5% of all diagnosed cancers worldwide and is characterized by early and aggressive metastasis. Current standa...

journal_title：BMJ (Clinical research ed.)

authors： Lee MS,Sanoff HK

更新日期：2020-12-07 00:00:00

abstract：:This article presents a study on the sexual lifestyle of long distance lorry drivers in India. Using a questionnaire survey method, a total of 5709 consecutive long distance lorry drivers were interviewed by three trained investigators between March 1994 and August 1994. Results showed that 87% (4949 men) of subject...

journal_title：BMJ (Clinical research ed.)

authors： Rao KS,Pilli RD,Rao AS,Chalam PS

更新日期：1999-01-16 00:00:00

abstract：OBJECTIVES:To compare the effectiveness of in vitro fertilisation with single embryo transfer or in vitro fertilisation in a modified natural cycle with that of intrauterine insemination with controlled ovarian hyperstimulation in terms of a healthy child. DESIGN:Multicentre, open label, three arm, parallel group, ran...

journal_title：BMJ (Clinical research ed.)

authors： Bensdorp AJ,Tjon-Kon-Fat RI,Bossuyt PM,Koks CA,Oosterhuis GJ,Hoek A,Hompes PG,Broekmans FJ,Verhoeve HR,de Bruin JP,van Golde R,Repping S,Cohlen BJ,Lambers MD,van Bommel PF,Slappendel E,Perquin D,Smeenk JM,Pelinck MJ,

更新日期：2015-01-09 00:00:00

abstract：OBJECTIVE:To assess whether using intensive blood pressure targets leads to lower blood pressure in a community population of people with prevalent cerebrovascular disease. DESIGN:Open label randomised controlled trial. SETTING:99 general practices in England, with participants recruited in 2009-11. PARTICIPANTS:Peo...

journal_title：BMJ (Clinical research ed.)

authors： Mant J,McManus RJ,Roalfe A,Fletcher K,Taylor CJ,Martin U,Virdee S,Greenfield S,Hobbs FD

更新日期：2016-02-24 00:00:00

abstract：OBJECTIVE:To estimate the comparative clinical efficacy and acceptability of non-surgical brain stimulation for the acute treatment of major depressive episodes in adults. DESIGN:Systematic review with pairwise and network meta-analysis. DATA SOURCES:Electronic search of Embase, PubMed/Medline, and PsycINFO up to 8 M...

journal_title：BMJ (Clinical research ed.)

authors： Mutz J,Vipulananthan V,Carter B,Hurlemann R,Fu CHY,Young AH

更新日期：2019-03-27 00:00:00

abstract：OBJECTIVES:To report on the country of training and ethnicity of consultants in different specialties in the NHS, on trends in intake to UK medical schools by ethnicity, and on the specialty choices made by UK medical graduates in different ethnic groups. DESIGN:Analysis of official databases of consultants and of stu...

journal_title：BMJ (Clinical research ed.)

authors： Goldacre MJ,Davidson JM,Lambert TW

更新日期：2004-09-11 00:00:00

abstract：:A study was conducted (a) to assess the number of patients registered with a south London general practice who over 11 weeks referred themselves to an accident and emergency department, (b) to identify the characteristics of those patients, and (c) to determine their perceptions of the services and resources available...

journal_title：BMJ (Clinical research ed.)

authors： Singh S

更新日期：1988-11-05 00:00:00

abstract：OBJECTIVE:To assess the risk of epileptic seizures in people with and without epilepsy after vaccination with a monovalent AS03 adjuvanted pandemic A/H1N1 influenza vaccine (Pandemrix; Glaxo SmithKline, Sweden). DESIGN:Register based self controlled case series. SETTING:Three Swedish counties (source population 750,0...

journal_title：BMJ (Clinical research ed.)

authors： Arnheim-Dahlström L,Hällgren J,Weibull CE,Sparén P

更新日期：2012-12-18 00:00:00

abstract：OBJECTIVES:To review completed trials assessing effect of hormone replacement therapy on subsequent risk of stroke, assessing stroke by pathological type, severity, and outcome. DESIGN:Systematic review of randomised controlled trials identified from the Cochrane Library, Embase, and Medline; reviews; and reference li...

journal_title：BMJ (Clinical research ed.)

authors： Bath PM,Gray LJ

更新日期：2005-02-12 00:00:00

abstract：OBJECTIVE:To determine the incidence of cervical cancer after several negative cervical smear tests at different ages. DESIGN:Prospective observational study of incidence of cervical cancer after the third consecutive negative result based on individual level data in a national registry of histopathology and cytopatho...

journal_title：BMJ (Clinical research ed.)

authors： Rebolj M,van Ballegooijen M,Lynge E,Looman C,Essink-Bot ML,Boer R,Habbema D

更新日期：2009-04-24 00:00:00

abstract：:The Health of the Nation white paper set a target for 15% reduction in overall suicide rates by the year 2000. If the targets are to be achieved interventions must be identified which are of proved effectiveness. This paper examines the evidence on the available interventions and points of access to the population at ...

journal_title：BMJ (Clinical research ed.)

authors： Gunnell D,Frankel S

更新日期：1994-05-07 00:00:00

abstract：OBJECTIVE: To compare the effectiveness of flexible sigmoidoscopy in screening for colorectal cancer by patient sex and age. DESIGN: Pooled analysis of randomised trials (the US Prostate, Lung, Colorectal and Ovarian cancer screening trial (PLCO), the Italian Screening for Colon and Rectum trial (SCORE), and the Norwe...

journal_title：BMJ (Clinical research ed.)

authors： Holme Ø,Schoen RE,Senore C,Segnan N,Hoff G,Løberg M,Bretthauer M,Adami HO,Kalager M

更新日期：2017-01-13 00:00:00

abstract：:The introduction in Britain of advance directives--which allow a person to state in advance of becoming incompetent that they wish to take part in treatment decisions when no longer mentally competent--has now been advocated by the medical and legal establishments. The practical application of directives relating to h...

journal_title：BMJ (Clinical research ed.)

authors： Robertson GS

更新日期：1995-01-28 00:00:00

abstract：OBJECTIVE:To assess whether an assertive outreach intervention after suicide attempt could reduce the frequency of subsequent suicidal acts, compared with standard treatment. DESIGN:Randomised, parallel group, superiority trial with blinded outcome assessment. SETTING:Outpatient intervention at one location at Copenh...

journal_title：BMJ (Clinical research ed.)

authors： Morthorst B,Krogh J,Erlangsen A,Alberdi F,Nordentoft M

更新日期：2012-08-22 00:00:00

abstract：OBJECTIVES:To determine the accuracy and acceptability to patients of non-endoscopic screening for Barrett's oesophagus, using an ingestible oesophageal sampling device (Cytosponge) coupled with immunocytochemisty for trefoil factor 3. DESIGN:Prospective cohort study. SETTING:12 UK general practices, with gastroscopi...

journal_title：BMJ (Clinical research ed.)

authors： Kadri SR,Lao-Sirieix P,O'Donovan M,Debiram I,Das M,Blazeby JM,Emery J,Boussioutas A,Morris H,Walter FM,Pharoah P,Hardwick RH,Fitzgerald RC

更新日期：2010-09-10 00:00:00

abstract：UNLABELLED:OBJECTIVE-To assess the risk of cardiorespiratory symptoms and mortality in non-smokers who were passively exposed to environmental smoke. DESIGN:Prospective study of cohort from general population first screened between 1972 and 1976 and followed up for an average of 11.5 years, with linkage of data from p...

journal_title：BMJ (Clinical research ed.)

authors： Hole DJ,Gillis CR,Chopra C,Hawthorne VM

更新日期：1989-08-12 00:00:00

abstract：OBJECTIVES:To examine the risk of atrial fibrillation in relation to the whole spectrum of thyroid function in a large cohort of patients. DESIGN:Population based cohort study of general practice patients identified by linkage of nationwide registries at the individual level. SETTING:Primary care patients in the city...

journal_title：BMJ (Clinical research ed.)

authors： Selmer C,Olesen JB,Hansen ML,Lindhardsen J,Olsen AM,Madsen JC,Faber J,Hansen PR,Pedersen OD,Torp-Pedersen C,Gislason GH

更新日期：2012-11-27 00:00:00

abstract：:Ruben Meerman and Andrew Brown explain why the answer might not be what you expect. ...

journal_title：BMJ (Clinical research ed.)

authors： Meerman R,Brown AJ

更新日期：2014-12-16 00:00:00

abstract：OBJECTIVE:To test the hypothesis that hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins) may decrease the risk of community acquired pneumonia. DESIGN:Population based case-control study. SETTING:Group Health, a large integrated healthcare delivery system. Population Immunocompetent, community dwelling ...

journal_title：BMJ (Clinical research ed.)

authors： Dublin S,Jackson ML,Nelson JC,Weiss NS,Larson EB,Jackson LA

更新日期：2009-06-16 00:00:00

abstract：OBJECTIVE:To undertake a cost effectiveness analysis comparing first and second generation endometrial ablative techniques, hysterectomy, and the levonorgestrel releasing intrauterine system (Mirena) for treating heavy menstrual bleeding. DESIGN:Model based economic evaluation with data from an individual patient data...

journal_title：BMJ (Clinical research ed.)

authors： Roberts TE,Tsourapas A,Middleton LJ,Champaneria R,Daniels JP,Cooper KG,Bhattacharya S,Barton PM

更新日期：2011-04-26 00:00:00

abstract：OBJECTIVES:To describe the change in first day infant mortality during 1935-87. To examine the hypothesis that excess first day mortality in the 1950s and 1960s was attributable to restricting oxygen for sick newborn infants. DESIGN:Time series analysis of first day infant mortality and stillbirth rates. SETTING:Engl...

journal_title：BMJ (Clinical research ed.)

authors： Whyte RK

更新日期：1992-02-08 00:00:00

abstract：OBJECTIVE:To examine association of different measures of serum lipid concentration and obesity with mortality in women. DESIGN:Prospective observational study initiated in 1968-9, follow up examination after 12 years, and follow up study based on death certificates after 20 years. SETTING:Gothenburg, Sweden. SUBJEC...

journal_title：BMJ (Clinical research ed.)

authors： Bengtsson C,Björkelund C,Lapidus L,Lissner L

更新日期：1993-11-27 00:00:00

abstract：OBJECTIVES:To clarify the type of fetal growth impairment associated with increased blood pressure in adult life, and to establish whether this association is influenced by obesity and is mediated through impairment of insulin action. DESIGN:Cross sectional survey with retrospective ascertainment of size at birth from...

journal_title：BMJ (Clinical research ed.)

authors： Leon DA,Koupilova I,Lithell HO,Berglund L,Mohsen R,Vagero D,Lithell UB,McKeigue PM

更新日期：1996-02-17 00:00:00

abstract：OBJECTIVES:To investigate whether the use of graduated compression stockings (GCS) offers any adjuvant benefit when pharmaco-thromboprophylaxis is used for venous thromboembolism prophylaxis in patients undergoing elective surgery. DESIGN:Open, multicentre, randomised, controlled, non-inferiority trial. SETTING:Seven...

journal_title：BMJ (Clinical research ed.)

authors： Shalhoub J,Lawton R,Hudson J,Baker C,Bradbury A,Dhillon K,Everington T,Gohel MS,Hamady Z,Hunt BJ,Stansby G,Warwick D,Norrie J,Davies AH,GAPS trial investigators.

更新日期：2020-05-13 00:00:00

abstract：:The aim of the study was to assess whether increased energy expenditure causes the negative energy balance (tissue catabolism) commonly seen in children with insulin dependent (type I) diabetes. Resting metabolic rate and thermogenesis induced by adrenaline were measured in five healthy children and 14 children with t...

journal_title：BMJ (Clinical research ed.)

authors： Müller MJ,von zur Mühlen A,Lautz HU,Schmidt FW,Daiber M,Hürter P

更新日期：1989-08-19 00:00:00