Serum complex of trypsin 2 and alpha 1 antitrypsin as diagnostic and prognostic marker of acute pancreatitis: clinical study in consecutive patients.

abstract：OBJECTIVE:To investigate the risk of glioma in adults in relation to mobile phone use. DESIGN:Population based case-control study with collection of personal interview data. SETTING:Five areas of the United Kingdom. PARTICIPANTS:966 people aged 18 to 69 years diagnosed with a glioma from 1 December 2000 to 29 Februa...

journal_title：BMJ (Clinical research ed.)

authors： Hepworth SJ,Schoemaker MJ,Muir KR,Swerdlow AJ,van Tongeren MJ,McKinney PA

更新日期：2006-04-15 00:00:00

abstract：OBJECTIVE:To study the processes involved in and impact of mergers between NHS trusts, including the effect on management costs. DESIGN:Cross sectional study involving in depth interviews and documentary analysis; case study to compare savings in management costs between case trusts and control trusts. SETTING:Nine t...

journal_title：BMJ (Clinical research ed.)

authors： Fulop N,Protopsaltis G,Hutchings A,King A,Allen P,Normand C,Walters R

更新日期：2002-08-03 00:00:00

abstract：OBJECTIVE:To systematically review and describe currently available approaches to supporting maintenance of weight loss in obese adults and to assess the evidence for the effectiveness of these interventions. DESIGN:Systematic review with meta-analysis. DATA SOURCES:Medline, PsycINFO, Embase, and the Cochrane Central...

journal_title：BMJ (Clinical research ed.)

authors： Dombrowski SU,Knittle K,Avenell A,Araújo-Soares V,Sniehotta FF

更新日期：2014-05-14 00:00:00

abstract：:Planning future policy for medicines poses difficult problems. The main players in the drug business have their own views as to how the world around them functions and how the future of medicines should be shaped. In this paper we show how a scenario analysis can provide a powerful teaching device to readjust peoples'...

journal_title：BMJ (Clinical research ed.)

authors： Leufkens H,Haaijer-Ruskamp F,Bakker A,Dukes G

更新日期：1994-10-29 00:00:00

abstract：OBJECTIVES:To assess whether supplementation with antioxidants, folinic acid, or both improves the psychomotor and language development of children with Down's syndrome. DESIGN:Randomised controlled trial with two by two factorial design. SETTING:Children living in the Midlands, Greater London, and the south west of ...

journal_title：BMJ (Clinical research ed.)

authors： Ellis JM,Tan HK,Gilbert RE,Muller DP,Henley W,Moy R,Pumphrey R,Ani C,Davies S,Edwards V,Green H,Salt A,Logan S

更新日期：2008-03-15 00:00:00

abstract：OBJECTIVES:To evaluate the effectiveness of a self help approach to smoking cessation in pregnancy. DESIGN:Pragmatic cluster randomised controlled trial with community midwife as the unit of randomisation. SETTING:Three NHS hospital trusts in England. PARTICIPANTS:1527 women who smoked at the start of pregnancy. IN...

journal_title：BMJ (Clinical research ed.)

authors： Moore L,Campbell R,Whelan A,Mills N,Lupton P,Misselbrook E,Frohlich J

更新日期：2002-12-14 00:00:00

abstract：OBJECTIVES:To evaluate the use of a maternity unit run by general practitioners and midwives, describing the outcome of labour in an unselected group of women and quantifying the contribution made by general practitioners. DESIGN:Retrospective population based review of obstetric patients who had access to an isolated...

journal_title：BMJ (Clinical research ed.)

authors： Baird AG,Jewell D,Walker JJ

更新日期：1996-01-27 00:00:00

abstract：OBJECTIVES:To estimate the amount spent on specific hospital care by health agencies in 1993-4 and compare it with the resources allocated to patients registered with fundholding practices for the same type of care. To investigate whether fundholding practices and health agencies pay different amounts for inpatient car...

journal_title：BMJ (Clinical research ed.)

authors： Dixon J,Dinwoodie M,Hodson D,Dodd S,Poltorak T,Garrett C,Rice P,Doncaster I,Williams M

更新日期：1994-07-02 00:00:00

abstract：OBJECTIVE:To assess the association between genotype at the insertion or deletion polymorphism of the angiotensin converting enzyme gene and risk of coronary restenosis after percutaneous coronary intervention. DESIGN:Meta-analysis of studies before July 2001 that reported on these genotypes and risk of coronary reste...

journal_title：BMJ (Clinical research ed.)

authors： Bonnici F,Keavney B,Collins R,Danesh J

更新日期：2002-09-07 00:00:00

abstract：OBJECTIVE:To assess whether causal criteria can be used to find out whether there is support in published research for maintaining that menopause causes depression. DESIGN:Ninety four articles from 30 years of research examining the relation of natural menopause to depression were traced by using Medline and systemati...

journal_title：BMJ (Clinical research ed.)

authors： Nicol-Smith L

更新日期：1996-11-16 00:00:00

abstract：OBJECTIVE:To determine whether genetic factors associated with established rheumatoid arthritis could, in combination with rheumatoid factor, predict the development of radiological erosions in patients with early symmetrical (rheumatoid-like) arthritis. DESIGN:Prospective study. SETTING:Teaching hospital, early arth...

journal_title：BMJ (Clinical research ed.)

authors： Emery P,Salmon M,Bradley H,Wordsworth P,Tunn E,Bacon PA,Waring R

更新日期：1992-12-05 00:00:00

abstract：OBJECTIVE:To evaluate the impact of the US Air Force suicide prevention programme on risk of suicide and other outcomes that share underlying risk factors. DESIGN:Cohort study with quasi-experimental design and analysis of cohorts before (1990-6) and after (1997-2002) the intervention. PARTICIPANTS:5,260,292 US Air F...

journal_title：BMJ (Clinical research ed.)

authors： Knox KL,Litts DA,Talcott GW,Feig JC,Caine ED

更新日期：2003-12-13 00:00:00

abstract：OBJECTIVE:This study updates work published in 1998, which found that of 47 rating instruments appearing on websites offering health information, 14 described how they were developed, five provided instructions for use, and none reported the interobserver reliability and construct validity of the measurements. DESIGN:...

journal_title：BMJ (Clinical research ed.)

authors： Gagliardi A,Jadad AR

更新日期：2002-03-09 00:00:00

abstract：OBJECTIVES: To provide contemporary estimates of the prevalence of microcephaly in Europe, determine if the diagnosis of microcephaly is consistent across Europe, and evaluate whether changes in prevalence would be detected using the current European surveillance performed by EUROCAT (the European Surveillance of Conge...

journal_title：BMJ (Clinical research ed.)

authors： Morris JK,Rankin J,Garne E,Loane M,Greenlees R,Addor MC,Arriola L,Barisic I,Bergman JE,Csaky-Szunyogh M,Dias C,Draper ES,Gatt M,Khoshnood B,Klungsoyr K,Kurinczuk JJ,Lynch C,McDonnell R,Nelen V,Neville AJ,O'Mahony

更新日期：2016-09-13 00:00:00

abstract：OBJECTIVES:To assess heat related mortalities in relation to climate within Europe. DESIGN:Observational population study. SETTING:North Finland, south Finland, Baden-Württemberg, Netherlands, London, north Italy, and Athens. SUBJECTS:People aged 65-74. MAIN OUTCOME MEASURES:Mortalities at temperatures above, below...

journal_title：BMJ (Clinical research ed.)

authors： Keatinge WR,Donaldson GC,Cordioli E,Martinelli M,Kunst AE,Mackenbach JP,Nayha S,Vuori I

更新日期：2000-09-16 00:00:00

abstract：OBJECTIVE:To examine associations between varenicline and the incidence of a range of adverse outcomes. DESIGN:Population based cohort study using within person analyses to control for confounding by indication. SETTING:Whole population of Sweden. PARTICIPANTS:7,917,436 people aged 15 and over, of whom 69,757 were t...

journal_title：BMJ (Clinical research ed.)

authors： Molero Y,Lichtenstein P,Zetterqvist J,Gumpert CH,Fazel S

更新日期：2015-06-02 00:00:00

abstract：:Objective To improve the selection of patients with acute ischaemic stroke for intra-arterial treatment using a clinical decision tool to predict individual treatment benefit.Design Multivariable regression modelling with data from two randomised controlled clinical trials.Setting 16 hospitals in the Netherlands (deri...

journal_title：BMJ (Clinical research ed.)

authors： Venema E,Mulder MJHL,Roozenbeek B,Broderick JP,Yeatts SD,Khatri P,Berkhemer OA,Emmer BJ,Roos YBWEM,Majoie CBLM,van Oostenbrugge RJ,van Zwam WH,van der Lugt A,Steyerberg EW,Dippel DWJ,Lingsma HF

更新日期：2017-05-03 00:00:00

abstract：OBJECTIVE:To investigate the association between tea drinking habits in Golestan province, northern Iran, and risk of oesophageal squamous cell carcinoma. DESIGN:Population based case-control study. In addition, patterns of tea drinking and temperature at which tea was drunk were measured among healthy participants in...

journal_title：BMJ (Clinical research ed.)

authors： Islami F,Pourshams A,Nasrollahzadeh D,Kamangar F,Fahimi S,Shakeri R,Abedi-Ardekani B,Merat S,Vahedi H,Semnani S,Abnet CC,Brennan P,Møller H,Saidi F,Dawsey SM,Malekzadeh R,Boffetta P

更新日期：2009-03-26 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of health checks by nurses in reducing risk factors for cardiovascular disease in patients from general practice. DESIGN:Randomised controlled trial. SETTING:Five urban general practices in Bedfordshire. SUBJECTS:2136 patients receiving an initial health check in 1989-91 and sch...

journal_title：BMJ (Clinical research ed.)

authors：

更新日期：1994-01-29 00:00:00

abstract：:Hepatitis B virus (HBV) is a global health problem that can lead to cirrhosis and hepatocellular carcinoma (HCC). Although HBV vaccination has reduced the prevalence Of HBV infection, the burden of disease remains high. Treatment with antiviral drugs reduces the risk of liver disease and the development of HCC, and it...

journal_title：BMJ (Clinical research ed.)

authors： Sundaram V,Kowdley K

更新日期：2015-10-21 00:00:00

abstract：OBJECTIVES:To examine the individual and combined associations of unhealthy behaviours (low/intermediate physical activity, consuming fruit and vegetables less than once a day, current smoking/short term ex-smoking, never/former/heavy alcohol drinking), assessed at start of follow-up, with hazard of disability among ol...

journal_title：BMJ (Clinical research ed.)

authors： Artaud F,Dugravot A,Sabia S,Singh-Manoux A,Tzourio C,Elbaz A

更新日期：2013-07-23 00:00:00

abstract：:Eleven euthyroid patients with severe Graves' eye disease were treated with intravenous methylprednisolone and followed up for six months or more by ophthalmological assessment, orbital computed tomography (CT), photographs, and antibody measurements. Papilloedema resolved in the single patient in whom it was present;...

journal_title：BMJ (Clinical research ed.)

authors： Kendall-Taylor P,Crombie AL,Stephenson AM,Hardwick M,Hall K

更新日期：1988-12-17 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of post-diagnosis dementia treatment and coordination of care by memory clinics compared with general practitioners. DESIGN:Multicentre randomised controlled trial. SETTING:Nine memory clinics and 159 general practitioners in the Netherlands. PARTICIPANTS:175 patients with a ne...

journal_title：BMJ (Clinical research ed.)

authors： Meeuwsen EJ,Melis RJ,Van Der Aa GC,Golüke-Willemse GA,De Leest BJ,Van Raak FH,Schölzel-Dorenbos CJ,Verheijen DC,Verhey FR,Visser MC,Wolfs CA,Adang EM,Olde Rikkert MG

更新日期：2012-05-15 00:00:00

abstract：OBJECTIVES:To investigate the association between contemporary combined hormonal contraceptives (including progestogen types in combined preparations and all progestogen-only products) and overall and specific types of ovarian cancer. DESIGN:Prospective, nationwide cohort study. SETTING:Denmark, 1995-2014. PARTICIPA...

journal_title：BMJ (Clinical research ed.)

authors： Iversen L,Fielding S,Lidegaard Ø,Mørch LS,Skovlund CW,Hannaford PC

更新日期：2018-09-26 00:00:00

abstract：OBJECTIVE:To identify modifiable factors that influence relatives' decision to allow organ donation. DESIGN:Systematic review. DATA SOURCES:Medline, Embase, and CINAHL, without language restriction, searched to April 2008. Review methods Three authors independently assessed the eligibility of the identified studies. ...

journal_title：BMJ (Clinical research ed.)

authors： Simpkin AL,Robertson LC,Barber VS,Young JD

更新日期：2009-04-21 00:00:00

abstract：OBJECTIVES:To determine prospectively the rates of change in bone mineral density in elderly people and to examine the relation between lifestyle and demographic factors and these rates of change. DESIGN:Longitudinal population based study. SETTING:Dubbo, New South Wales, Australia. SUBJECTS:Representative sample (n...

journal_title：BMJ (Clinical research ed.)

authors： Jones G,Nguyen T,Sambrook P,Kelly PJ,Eisman JA

更新日期：1994-09-17 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of emotionalism after stroke, to assess its relation with other mood disorders, and to identify clinical variables with which it is associated. DESIGN:Descriptive study of a cohort of patients consecutively entered on a community stroke register. SETTING:Community based research p...

journal_title：BMJ (Clinical research ed.)

authors： House A,Dennis M,Molyneux A,Warlow C,Hawton K

更新日期：1989-04-15 00:00:00

abstract：OBJECTIVE:To assess the risk of pulmonary embolism, ischaemic stroke, and myocardial infarction associated with combined oral contraceptives according to dose of oestrogen (ethinylestradiol) and progestogen. DESIGN:Observational cohort study. SETTING:Data from the French national health insurance database linked with...

journal_title：BMJ (Clinical research ed.)

authors： Weill A,Dalichampt M,Raguideau F,Ricordeau P,Blotière PO,Rudant J,Alla F,Zureik M

更新日期：2016-05-10 00:00:00

abstract：OBJECTIVE:To investigate the variation in prescribing among general practices by examining the contribution to this variation of fundholding, training status, partnership status, and the level of deprivation in the practice population and to investigate the extent to which fundholding has been responsible for any chang...

journal_title：BMJ (Clinical research ed.)

authors： Wilson RP,Hatcher J,Barton S,Walley T

更新日期：1996-09-07 00:00:00

abstract：OBJECTIVE:To investigate the effect of immediate feedback from a point of care test for salivary nicotine metabolites in promoting smoking cessation and reduction in tobacco use. DESIGN:Prospective, operator blinded, randomised controlled trial. SETTING:General dental practice, London. PARTICIPANTS:100 adult smokers...

journal_title：BMJ (Clinical research ed.)

authors： Barnfather KD,Cope GF,Chapple IL

更新日期：2005-10-29 00:00:00