Management of chronic hepatitis B infection.

abstract：OBJECTIVE:To examine the association between intake of different types of alcoholic drinks and mortality. DESIGN:Prospective population study with baseline assessment of alcohol intake, smoking habit, income, education, and body mass index, and 10-12 years' follow up of mortality. SETTING:Copenhagen city heart study,...

journal_title：BMJ (Clinical research ed.)

authors： Grønbaek M,Deis A,Sørensen TI,Becker U,Schnohr P,Jensen G

更新日期：1995-05-06 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of serious maternal complications after the use of various tocolytic drugs for the treatment of preterm labour in routine clinical situations. DESIGN:Prospective cohort study. SETTING:28 hospitals in the Netherlands and Belgium. PARTICIPANTS:1920 consecutive women treated with toc...

journal_title：BMJ (Clinical research ed.)

authors： de Heus R,Mol BW,Erwich JJ,van Geijn HP,Gyselaers WJ,Hanssens M,Härmark L,van Holsbeke CD,Duvekot JJ,Schobben FF,Wolf H,Visser GH

更新日期：2009-03-05 00:00:00

abstract：:Several forces have resulted in the creation in Tayside of the first formally integrated unit of undergraduate and postgraduate education in general practice in the United Kingdom. Forces that helped this integration included the desire for change, national developments in education, financial support through funds se...

journal_title：BMJ (Clinical research ed.)

authors： Bain J,Scott R,Snadden D

更新日期：1995-06-17 00:00:00

abstract：OBJECTIVES:To estimate survival after a diagnosis of dementia in primary care, compared with people without dementia, and to determine incidence of dementia. DESIGN:Cohort study using data from The Health Improvement Network (THIN), a primary care database. SETTING:353 general practices in the United Kingdom providin...

journal_title：BMJ (Clinical research ed.)

authors： Rait G,Walters K,Bottomley C,Petersen I,Iliffe S,Nazareth I

更新日期：2010-08-05 00:00:00

abstract：OBJECTIVE:To compare four potential screening strategies, and subsequent interventions, for the prevention and treatment of type 2 diabetes: (a) screening for type 2 diabetes to enable early detection and treatment, (b) screening for type 2 diabetes and impaired glucose tolerance, intervening with lifestyle interventio...

journal_title：BMJ (Clinical research ed.)

authors： Gillies CL,Lambert PC,Abrams KR,Sutton AJ,Cooper NJ,Hsu RT,Davies MJ,Khunti K

更新日期：2008-05-24 00:00:00

abstract：OBJECTIVE:To analyse the cost effectiveness of a national programme to screen blood donors for infection with the human T cell leukaemia/lymphoma virus. DESIGN:Three models for calculating the costs and benefits of screening were developed. The first model analysed the cost of continuously testing all donations; the s...

journal_title：BMJ (Clinical research ed.)

authors： Tynell E,Andersson S,Lithander E,Arneborn M,Blomberg J,Hansson HB,Krook A,Nomberg M,Ramstedt K,Shanwell A,Bjorkman A

更新日期：1998-05-09 00:00:00

abstract：:The author is one of the medical advisers to the judge who led a government inquiry into allegations that an experimental research program at the National Women's Hospital in Auckland, New Zealand, to study the natural course of cervical carcinoma in situ had withheld conventional treatment from some patients. She ar...

journal_title：BMJ (Clinical research ed.)

authors： Paul C

更新日期：1988-08-20 00:00:00

abstract：OBJECTIVE:To examine whether there are too many hospital beds in London. DESIGN:Analysis of data from the Hospital In-Patient Enquiry, Mental Health Enquiry, health service indicators, and Emergency Bed Service. SETTING:England, London, and inner London. RESULTS:Hospital admission rates for acute plus geriatric serv...

journal_title：BMJ (Clinical research ed.)

authors： Jarman B

更新日期：1993-04-10 00:00:00

abstract：OBJECTIVE:To quantify the association between exposure to higher temperatures and the risk of myocardial infarction at an hourly temporal resolution. DESIGN:Case-crossover study. SETTING:England and Wales Myocardial Ischaemia National Audit Project (MINAP) database. PARTICIPANTS:24,861 hospital admissions for myocar...

journal_title：BMJ (Clinical research ed.)

authors： Bhaskaran K,Armstrong B,Hajat S,Haines A,Wilkinson P,Smeeth L

更新日期：2012-12-13 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of emotionalism after stroke, to assess its relation with other mood disorders, and to identify clinical variables with which it is associated. DESIGN:Descriptive study of a cohort of patients consecutively entered on a community stroke register. SETTING:Community based research p...

journal_title：BMJ (Clinical research ed.)

authors： House A,Dennis M,Molyneux A,Warlow C,Hawton K

更新日期：1989-04-15 00:00:00

abstract：OBJECTIVE:To discover whether the wartime government evacuation of children from London and other population centres to rural districts was associated with any increase in childhood leukaemia. DESIGN:Observational study of mortality from leukaemia among the childhood population of England and Wales in relation to the ...

journal_title：BMJ (Clinical research ed.)

authors： Kinlen LJ,John SM

更新日期：1994-11-05 00:00:00

abstract：OBJECTIVE:To determine if any excess of childhood leukaemia was associated with the large and increasing numbers of national military servicemen in 1949 and 1950, particularly in rural districts. This would be a further test of the hypothesis that childhood leukaemia can originate in an infection, the transmission of w...

journal_title：BMJ (Clinical research ed.)

authors： Kinlen LJ,Hudson C

更新日期：1991-11-30 00:00:00

abstract：:Chronic insomnia is a common condition that affects people worldwide and has negative effects on patients' health and wellbeing. The treatment of insomnia can be complex and time consuming for patients and providers. Although behavioral interventions are the first line therapy, there are barriers to access for these t...

journal_title：BMJ (Clinical research ed.)

authors： Kay-Stacey M,Attarian H

更新日期：2016-07-06 00:00:00

abstract：OBJECTIVES:To determine the prevalence and associations of symptoms of fatigue. DESIGN:Questionnaire survey. SETTING:London general practice. PARTICIPANTS:611 General practice attenders. MAIN OUTCOME MEASURES:Scores on a fatigue questionnaire and reasons given for fatigue. RESULTS:10.2% Of men (17/167) and 10.6% o...

journal_title：BMJ (Clinical research ed.)

authors： David A,Pelosi A,McDonald E,Stephens D,Ledger D,Rathbone R,Mann A

更新日期：1990-11-24 00:00:00

abstract：OBJECTIVE:To identify modifiable factors that influence relatives' decision to allow organ donation. DESIGN:Systematic review. DATA SOURCES:Medline, Embase, and CINAHL, without language restriction, searched to April 2008. Review methods Three authors independently assessed the eligibility of the identified studies. ...

journal_title：BMJ (Clinical research ed.)

authors： Simpkin AL,Robertson LC,Barber VS,Young JD

更新日期：2009-04-21 00:00:00

abstract：OBJECTIVE:To determine whether a decision aid designed for adults with low education and literacy can support informed choice and involvement in decisions about screening for bowel cancer. DESIGN:Randomised controlled trial. SETTING:Areas in New South Wales, Australia identified as socioeconomically disadvantaged (lo...

journal_title：BMJ (Clinical research ed.)

authors： Smith SK,Trevena L,Simpson JM,Barratt A,Nutbeam D,McCaffery KJ

更新日期：2010-10-26 00:00:00

abstract：OBJECTIVE:To examine changes in representation of women among first authors of original research published in high impact general medical journals from 1994 to 2014 and investigate differences between journals. DESIGN:Observational study. STUDY SAMPLE:All original research articles published in Annals of Internal Med...

journal_title：BMJ (Clinical research ed.)

authors： Filardo G,da Graca B,Sass DM,Pollock BD,Smith EB,Martinez MA

更新日期：2016-03-02 00:00:00

abstract：OBJECTIVES:To examine the prospective associations between consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice with type 2 diabetes before and after adjustment for adiposity, and to estimate the population attributable fraction for type 2 diabetes from consumption of sugar sweete...

journal_title：BMJ (Clinical research ed.)

authors： Imamura F,O'Connor L,Ye Z,Mursu J,Hayashino Y,Bhupathiraju SN,Forouhi NG

更新日期：2015-07-21 00:00:00

abstract：OBJECTIVE:To compare the mortality of patients in a palliative care unit on working days with that on weekends and public holidays. DESIGN:Retrospective database study. SETTING:Palliative care unit in Germany. POPULATION:All admissions to palliative care unit between 1 January 1997 and 31 December 2008. MAIN OUTCOM...

journal_title：BMJ (Clinical research ed.)

authors： Voltz R,Kamps R,Greinwald R,Hellmich M,Hamacher S,Becker G,Kuhr K,Gaertner J

更新日期：2014-12-16 00:00:00

abstract：OBJECTIVE:To determine the global capacity (availability, accessibility, quality, and affordability) to deliver kidney replacement therapy (dialysis and transplantation) and conservative kidney management. DESIGN:International cross sectional survey. SETTING:International Society of Nephrology (ISN) survey of 182 cou...

journal_title：BMJ (Clinical research ed.)

authors： Bello AK,Levin A,Lunney M,Osman MA,Ye F,Ashuntantang GE,Bellorin-Font E,Benghanem Gharbi M,Davison SN,Ghnaimat M,Harden P,Htay H,Jha V,Kalantar-Zadeh K,Kerr PG,Klarenbach S,Kovesdy CP,Luyckx VA,Neuen BL,O'Donoghue D

更新日期：2019-10-31 00:00:00

abstract：OBJECTIVE:To study the impact of skin surgery in general practice on the workload of a pathology laboratory and to identify what further training might be helpful. DESIGN:Analysis of skin biopsy specimens from general practitioners before and after their new contract to determine numbers of specimens, changes in diagn...

journal_title：BMJ (Clinical research ed.)

authors： Cox NH,Wagstaff R,Popple AW

更新日期：1992-01-11 00:00:00

abstract：:Telephone helplines are an effective way of dealing with health related incidents in which large numbers of people need personal counselling or information for reassurance or case finding. Helplines often have to be set up at short notice, which is labour intensive and makes recruitment of appropriate staff difficult....

journal_title：BMJ (Clinical research ed.)

authors： Stark C,Christie P,Marr AC

更新日期：1994-07-02 00:00:00

abstract：OBJECTIVES:To describe utilisation of general practitioners by elderly people resident in communal establishments; to examine variations in general practitioner utilisation and estimate the likely impact of the "downsizing" of long stay provision in NHS hospitals. DESIGN:Secondary analyses of the survey of disability ...

journal_title：BMJ (Clinical research ed.)

authors： Kavanagh S,Knapp M

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of day hospital attendance in prolonging independent living for elderly people. DESIGN:Systematic review of 12 controlled clinical trials (available by January 1997) comparing day hospital care with comprehensive care (five trials), domiciliary care (four trials), or no comprehen...

journal_title：BMJ (Clinical research ed.)

authors： Forster A,Young J,Langhorne P

更新日期：1999-03-27 00:00:00

abstract：OBJECTIVES:To investigate the cost effectiveness of cyclo-oxygenase-2 (COX 2) selective inhibitors and traditional non-steroidal anti-inflammatory drugs (NSAIDs), and the addition of proton pump inhibitors to these treatments, for people with osteoarthritis. DESIGN:An economic evaluation using a Markov model and data ...

journal_title：BMJ (Clinical research ed.)

authors： Latimer N,Lord J,Grant RL,O'Mahony R,Dickson J,Conaghan PG,National Institute for Health and Clinical Excellence Osteoarthritis Guideline Development Group.

更新日期：2009-07-14 00:00:00

abstract：OBJECTIVE:To identify and explore parents' concerns when young children become acutely ill. DESIGN:Qualitative study making use of semi-structured one to one and group interviews with parents of preschool children. SETTING:Disadvantaged inner city community. SUBJECTS:95 parents of preschool children. RESULTS:Fever,...

journal_title：BMJ (Clinical research ed.)

authors： Kai J

更新日期：1996-10-19 00:00:00

abstract：OBJECTIVES:To evaluate the effect of daily zinc supplementation in children on the incidence of acute lower respiratory tract infections and pneumonia. DESIGN:Double masked, randomised placebo controlled trial. SETTING:A slum community in New Delhi, India. PARTICIPANTS:2482 children aged 6 to 30 months. INTERVENTIO...

journal_title：BMJ (Clinical research ed.)

authors： Bhandari N,Bahl R,Taneja S,Strand T,Mølbak K,Ulvik RJ,Sommerfelt H,Bhan MK

更新日期：2002-06-08 00:00:00

abstract：OBJECTIVES:To investigate the association between environmental tobacco smoke, plasma cotinine concentration, and respiratory cancer or death. DESIGN:Nested case-control study within the European prospective investigation into cancer and nutrition (EPIC). PARTICIPANTS:303,020 people from the EPIC cohort (total 500,00...

journal_title：BMJ (Clinical research ed.)

authors： Vineis P,Airoldi L,Veglia F,Olgiati L,Pastorelli R,Autrup H,Dunning A,Garte S,Gormally E,Hainaut P,Malaveille C,Matullo G,Peluso M,Overvad K,Tjonneland A,Clavel-Chapelon F,Boeing H,Krogh V,Palli D,Panico S,Tumino

更新日期：2005-02-05 00:00:00

abstract：OBJECTIVES:To investigate current practice of screening children from abroad for infections after coming to the United Kingdom, and to make recommendations for future practice. DESIGN:A review of literature and a questionnaire sent to all health authorities and boards in the United Kingdom. SETTING:All health authori...

journal_title：BMJ (Clinical research ed.)

authors： Shabde N,Waterston T

更新日期：1990-10-06 00:00:00

abstract：OBJECTIVE:To study the circumstances of dog bites and identify risk factors. DESIGN:Postal questionnaire survey and case note review of victims of dog bites referred between 1982 and 1989. SETTING:One referral based regional plastic surgery unit. PATIENTS:146 consecutive patients referred for primary treatment of do...

journal_title：BMJ (Clinical research ed.)

authors： Shewell PC,Nancarrow JD

更新日期：1991-12-14 00:00:00