Varenicline and risk of psychiatric conditions, suicidal behaviour, criminal offending, and transport accidents and offences: population based cohort study.

abstract：:Elderly and disabled people have been led to expect great improvements in the quality of community care after April 1993. The choice to live safely at home is to be offered as an alternative to residential care. The financial and organisational relationships are all intended to support this in practice. The Tomlinson ...

journal_title：BMJ (Clinical research ed.)

authors： Jowell T

更新日期：1992-12-05 00:00:00

abstract：OBJECTIVE:To estimate the risk of breast cancer associated with diagnostic radiation in carriers of BRCA1/2 mutations. DESIGN:Retrospective cohort study (GENE-RAD-RISK). SETTING:Three nationwide studies (GENEPSO, EMBRACE, HEBON) in France, United Kingdom, and the Netherlands, PARTICIPANTS:1993 female carriers of BRC...

journal_title：BMJ (Clinical research ed.)

authors： Pijpe A,Andrieu N,Easton DF,Kesminiene A,Cardis E,Noguès C,Gauthier-Villars M,Lasset C,Fricker JP,Peock S,Frost D,Evans DG,Eeles RA,Paterson J,Manders P,van Asperen CJ,Ausems MG,Meijers-Heijboer H,Thierry-Chef I,Hau

更新日期：2012-09-06 00:00:00

abstract：OBJECTIVE:To assess the risk of bias associated with missing outcome data in systematic reviews. DESIGN:Imputation study. SETTING:Systematic reviews. POPULATION:100 systematic reviews that included a group level meta-analysis with a statistically significant effect on a patient important dichotomous efficacy outcome...

journal_title：BMJ (Clinical research ed.)

authors： Kahale LA,Khamis AM,Diab B,Chang Y,Lopes LC,Agarwal A,Li L,Mustafa RA,Koujanian S,Waziry R,Busse JW,Dakik A,Schünemann HJ,Hooft L,Scholten RJ,Guyatt GH,Akl EA

更新日期：2020-08-26 00:00:00

abstract：:Managed care has entered the lexicon of healthcare reform, but confusion and ignorance surround its meaning and purpose. It seeks to cut the costs of health care while maintaining its quality, but the evidence that it is able to achieve these aims is mixed. As well as raising awareness and understanding of the issues ...

journal_title：BMJ (Clinical research ed.)

authors： Fairfield G,Hunter DJ,Mechanic D,Rosleff F

更新日期：1997-06-21 00:00:00

abstract：OBJECTIVE:To determine the relative importance of appropriate prescribing for asthma in explaining high rates of hospital admission for asthma among east London general practices. DESIGN:Poisson regression analysis describing relation of each general practice's admission rates for asthma with prescribing for asthma an...

journal_title：BMJ (Clinical research ed.)

authors： Griffiths C,Sturdy P,Naish J,Omar R,Dolan S,Feder G

更新日期：1997-02-15 00:00:00

abstract：OBJECTIVES:To investigate the effectiveness of non-benzodiazepine hypnotics (Z drugs) and associated placebo responses in adults and to evaluate potential moderators of effectiveness in a dataset used to approve these drugs. DESIGN:Systematic review and meta-analysis. DATA SOURCE:US Food and Drug Administration (FDA)...

journal_title：BMJ (Clinical research ed.)

authors： Huedo-Medina TB,Kirsch I,Middlemass J,Klonizakis M,Siriwardena AN

更新日期：2012-12-17 00:00:00

abstract：:Polls show increasing public interest in advance statements or directives about medical treatment ("living wills") but that few people, apart from Jehovah's Witnesses, carry such documents. Patients' firm, witnessed oral decisions are often sufficient to aid clinical decision making but should still be recorded in med...

journal_title：BMJ (Clinical research ed.)

authors： Sommerville A

更新日期：1995-06-24 00:00:00

abstract：:Preparing a review entails many judgments. The focus of the review must be decided. Studies that are relevant to the focus of the review must be identified, selected for inclusion and critically appraised. Information must be collected and synthesised from the relevant studies, and conclusions must be drawn. Checklist...

journal_title：BMJ (Clinical research ed.)

authors： Oxman AD

更新日期：1994-09-10 00:00:00

abstract：OBJECTIVE:To develop and validate a prognostic model for early death in patients with traumatic bleeding. DESIGN:Multivariable logistic regression of a large international cohort of trauma patients. SETTING:274 hospitals in 40 high, medium, and low income countries PARTICIPANTS:Prognostic model development: 20,127 t...

journal_title：BMJ (Clinical research ed.)

authors： Perel P,Prieto-Merino D,Shakur H,Clayton T,Lecky F,Bouamra O,Russell R,Faulkner M,Steyerberg EW,Roberts I

更新日期：2012-08-15 00:00:00

abstract：OBJECTIVES:To examine whether British South Asian children differ in insulin resistance, adiposity, and cardiovascular risk profile from white children. DESIGN:Cross sectional study. SETTING:Primary schools in 10 British towns. PARTICIPANTS:British children aged 8 to 11 years (227 South Asian and 3415 white); 73 Sou...

journal_title：BMJ (Clinical research ed.)

authors： Whincup PH,Gilg JA,Papacosta O,Seymour C,Miller GJ,Alberti KG,Cook DG

更新日期：2002-03-16 00:00:00

abstract：OBJECTIVES:To compare patterns of admission to hospital and prognosis in white and South Asian patients newly admitted with heart failure, and to evaluate the effect of personal characteristics and comorbidity on outcome. DESIGN:Historical cohort study. SETTING:UK district health authority (population 960,000). PART...

journal_title：BMJ (Clinical research ed.)

authors： Blackledge HM,Newton J,Squire IB

更新日期：2003-09-06 00:00:00

abstract：OBJECTIVES:To investigate patients' and family members' perceptions and experiences of disclosure of healthcare incidents and to derive principles of effective disclosure. DESIGN:Retrospective qualitative study based on 100 semi-structured, in depth interviews with patients and family members. SETTING:Nationwide mult...

journal_title：BMJ (Clinical research ed.)

authors： Iedema R,Allen S,Britton K,Piper D,Baker A,Grbich C,Allan A,Jones L,Tuckett A,Williams A,Manias E,Gallagher TH

更新日期：2011-07-25 00:00:00

abstract：OBJECTIVES:To provide insight into factors that contribute to the anxiety reported in a quantitative study of the psychological effect of screening for type 2 diabetes. To explore expectations of and reactions to the screening experience of patients with positive, negative, and intermediate results. DESIGN:Prospective...

journal_title：BMJ (Clinical research ed.)

authors： Eborall H,Davies R,Kinmonth AL,Griffin S,Lawton J

更新日期：2007-09-08 00:00:00

abstract：OBJECTIVE:To determine whether rates of suicide changed in Toronto after a barrier was erected at Bloor Street Viaduct, the bridge with the world's second highest annual rate of suicide by jumping after Golden Gate Bridge in San Francisco. DESIGN:Natural experiment. SETTING:City of Toronto and province of Ontario, Ca...

journal_title：BMJ (Clinical research ed.)

authors： Sinyor M,Levitt AJ

更新日期：2010-07-06 00:00:00

abstract：:A committee of French bishops has contradicted the Vatican's condemnation of all methods of contraception by acknowledging that condom use may be necessary in order to prevent the spread of HIV and protect against AIDS. The Social Commission of the French Episcopate made this statement in a book entitled AIDS: Societ...

journal_title：BMJ (Clinical research ed.)

authors： Dorozynski A

更新日期：1996-02-24 00:00:00

abstract：OBJECTIVE:To evaluate the effects of a multifaceted empowerment strategy on the actual use of single embryo transfer after in vitro fertilisation. DESIGN:Randomised controlled trial. SETTING:Five in vitro fertilisation clinics in the Netherlands. PARTICIPANTS:308 couples (women aged <40) on the waiting list for a fi...

journal_title：BMJ (Clinical research ed.)

authors： van Peperstraten A,Nelen W,Grol R,Zielhuis G,Adang E,Stalmeier P,Hermens R,Kremer J

更新日期：2010-09-30 00:00:00

abstract：:A brief note on the status of the AIDS pandemic, from the Amsterdam VIIIth International Conference on AIDS, warns that the course of the epidemic is not being altered by prevention efforts. AIDS occurs in every country, usually spread by heterosexual contact, so that women are equally affected with men. WHO estimat...

journal_title：BMJ (Clinical research ed.)

authors： Tanne JH

更新日期：1992-07-25 00:00:00

abstract：OBJECTIVES:(a) To investigate defensive medical practices among general practitioners; (b) to compare any such practices with general practitioners' understanding of certain aspects of the terms of service and medical negligence and practitioners' concerns about the risk of being sued or having a complaint lodged. DES...

journal_title：BMJ (Clinical research ed.)

authors： Summerton N

更新日期：1995-01-07 00:00:00

abstract：OBJECTIVE: To identify and characterise non-specific immunological effects after routine childhood vaccines against BCG, measles, diphtheria, pertussis, and tetanus. DESIGN: Systematic review of randomised controlled trials, cohort studies, and case-control studies. DATA SOURCES: Embase, PubMed, Cochrane library, and...

journal_title：BMJ (Clinical research ed.)

authors： Kandasamy R,Voysey M,McQuaid F,de Nie K,Ryan R,Orr O,Uhlig U,Sande C,O'Connor D,Pollard AJ

更新日期：2016-10-13 00:00:00

abstract：OBJECTIVES:To measure the prevalence of domestic violence among women attending general practice; test the association between experience of domestic violence and demographic factors; evaluate the extent of recording of domestic violence in records held by general practices; and assess acceptability to women of screeni...

journal_title：BMJ (Clinical research ed.)

authors： Richardson J,Coid J,Petruckevitch A,Chung WS,Moorey S,Feder G

更新日期：2002-02-02 00:00:00

abstract：OBJECTIVES:To investigate the effect of milk supplementation on total body bone mineral acquisition in adolescent girls. DESIGN:18 month, open randomised intervention trial. SUBJECTS:82 white girls aged 12.2 (SD 0.3) years, recruited from four secondary schools in Sheffield. INTERVENTION:568 ml (one pint) of whole o...

journal_title：BMJ (Clinical research ed.)

authors： Cadogan J,Eastell R,Jones N,Barker ME

更新日期：1997-11-15 00:00:00

abstract：:Chronic insomnia is a common condition that affects people worldwide and has negative effects on patients' health and wellbeing. The treatment of insomnia can be complex and time consuming for patients and providers. Although behavioral interventions are the first line therapy, there are barriers to access for these t...

journal_title：BMJ (Clinical research ed.)

authors： Kay-Stacey M,Attarian H

更新日期：2016-07-06 00:00:00

abstract：:Objective To estimate the cumulative radiation exposure and lifetime attributable risk of cancer incidence associated with lung cancer screening using annual low dose computed tomography (CT).Design Secondary analysis of data from a lung cancer screening trial and risk-benefit analysis.Setting 10 year, non-randomised,...

journal_title：BMJ (Clinical research ed.)

authors： Rampinelli C,De Marco P,Origgi D,Maisonneuve P,Casiraghi M,Veronesi G,Spaggiari L,Bellomi M

更新日期：2017-02-08 00:00:00

abstract：OBJECTIVE:To examine the association between obstetric epidural anaesthesia and subsequent long term problems. DESIGN:Postal questionnaire on health problems after childbirth linked to maternity case note data. SETTING:Maternity hospital in Birmingham. SUBJECTS:11701 women who delivered their most recent child durin...

journal_title：BMJ (Clinical research ed.)

authors： MacArthur C,Lewis M,Knox EG

更新日期：1992-05-16 00:00:00

abstract：OBJECTIVE:To assess the impact on birth size and risk of low birth weight of alternative combinations of micronutrients given to pregnant women. DESIGN:Double blind cluster randomised controlled trial. SETTING:Rural community in south eastern Nepal. PARTICIPANTS:4926 pregnant women and 4130 live born infants. INTER...

journal_title：BMJ (Clinical research ed.)

authors： Christian P,Khatry SK,Katz J,Pradhan EK,LeClerq SC,Shrestha SR,Adhikari RK,Sommer A,West KP Jr

更新日期：2003-03-15 00:00:00

abstract：OBJECTIVE:To determine whether prophylactic treatment with low molecular weight heparin reduces the incidence of thrombosis in patients who have had general or orthopaedic surgery. DESIGN:Meta-analysis of results from 52 randomised, controlled clinical studies (29 in general surgery and 23 in orthopaedic surgery) in w...

journal_title：BMJ (Clinical research ed.)

authors： Leizorovicz A,Haugh MC,Chapuis FR,Samama MM,Boissel JP

更新日期：1992-10-17 00:00:00

abstract：OBJECTIVE:To investigate the clinical effects of regulating umbilical cord clamping in preterm infants. DESIGN:A prospective randomised study. SETTING:The Queen Mother's Hospital, Glasgow. SUBJECTS:36 vaginally delivered infants over 27 and under 33 weeks' gestation. INTERVENTION:Holding the infant 20 cm below the ...

journal_title：BMJ (Clinical research ed.)

authors： Kinmond S,Aitchison TC,Holland BM,Jones JG,Turner TL,Wardrop CA

更新日期：1993-01-16 00:00:00

abstract：OBJECTIVE:To investigate explanations for social inequalities in health with respect to health related social mobility and cumulative socioeconomic circumstances over the first three decades of life. DESIGN:Longitudinal follow up. SETTING:Great Britain. SUBJECTS:Data from the 1958 birth cohort study (all children bo...

journal_title：BMJ (Clinical research ed.)

authors： Power C,Matthews S,Manor O

更新日期：1996-08-24 00:00:00

abstract：OBJECTIVE:To determine the contribution of inheritance to the incidence of squamous cell carcinoma of the head and neck. DESIGN:Historical cohort study. First degree relatives of cases with squamous cell carcinoma of the head and neck made up the exposed cohort and first degree relatives of spouses of cases made up th...

journal_title：BMJ (Clinical research ed.)

authors： Foulkes WD,Brunet JS,Sieh W,Black MJ,Shenouda G,Narod SA

更新日期：1996-09-21 00:00:00

abstract：OBJECTIVE:To investigate the association between several types of soy products and all cause and cause specific mortality. DESIGN:Population based cohort study. SETTING:Japan Public Health Centre-based Prospective Study, which includes 11 public health centre areas in Japan. PARTICIPANTS:92 915 participants (42 750 ...

journal_title：BMJ (Clinical research ed.)

authors： Katagiri R,Sawada N,Goto A,Yamaji T,Iwasaki M,Noda M,Iso H,Tsugane S,Japan Public Health Center-based Prospective Study Group.

更新日期：2020-01-29 00:00:00