Clinical Value of CT for Differentiation between Ascites and Hemorrhage: An Experimental In-Vitro Study.

Abstract:

BACKGROUND:Abdominal trauma, leading to intra-abdominal bleeding, is a life-threatening condition that might need emergency surgical intervention. Sonography and Computed Tomography (CT) are most commonly used to detect free intra-abdominal fluid. This study investigates the accuracy of CT to distinguish between ascites and intra-abdominal hemorrhage. METHODS:Ascites were collected during a clinical routine. Three serial dilutions, mixing ascites with whole blood samples of the patient and with two blood group identical donors, were prepared. Laboratory-chemical analysis and radiological evaluation using CT with measurement of average Hounsfield Units (HU) were performed. RESULTS:Between ascites and whole blood as well as between ascites and the 1:1-ratio-samples, HU values differed significantly (p < 0.001). All further dilutions showed HU values with no significant difference compared to ascites (p ≥ 0.42). Whole blood showed significantly higher HU values than ascites and every step of the serial dilutions (p < 0.001). Measured HU values were also dependent on time and the exact point of measurement in the micro reaction vessels. CONCLUSIONS:In patients suffering from blunt abdominal trauma with preexisting ascites, HU values in CT imaging are not valid enough to exclude an acute hemorrhage.

journal_name

J Clin Med

authors

Kerschbaum M,Schurr LA,Riedl M,Mayr A,Weiß I,Klute L,Popp D,Pfeifer C,Ernstberger A,Alt V,Dendl LM

doi

10.3390/jcm10010076

subject

Has Abstract

pub_date

2020-12-28 00:00:00

issue

1

issn

2077-0383

pii

jcm10010076

journal_volume

10

pub_type

杂志文章
  • Metoclopramide and Levosulpiride Use and Subsequent Levodopa Prescription in the Korean Elderly: The Prescribing Cascade.

    abstract::The aim of this study was to investigate the prescribing cascade phenomenon of dopaminergic drugs such as levodopa in the management of gastroprokinetic drugs induced parkinsonism. Based on the Korea National Health Insurance Service (NHIS)-Senior Cohort Database, we analyzed patients aged ≥65 years, between 2009 and ...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8091496

    authors: Huh Y,Kim DH,Choi M,Park JH,Kwon DY,Jung JH,Han K,Park YG

    更新日期:2019-09-19 00:00:00

  • Outcomes of Inhaled Amikacin and Clofazimine-Containing Regimens for Treatment of Refractory Mycobacterium avium Complex Pulmonary Disease.

    abstract::Limited data are available regarding optimal treatment for refractory Mycobacterium avium complex-pulmonary disease (MAC-PD). We evaluated outcomes of inhaled amikacin (AMK) with clofazimine (CFZ) regimens as an add-on salvage therapy for refractory MAC-PD. We retrospectively analyzed 52 patients with refractory MAC-P...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9092968

    authors: Kim BG,Kim H,Kwon OJ,Huh HJ,Lee NY,Baek SY,Sohn I,Jhun BW

    更新日期:2020-09-14 00:00:00

  • Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?

    abstract::Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan, China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The severe form of the disease is often associated with acute respiratory distress syndrome (ARDS), and most critically ill patients ...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm9092762

    authors: Gardin C,Ferroni L,Chachques JC,Zavan B

    更新日期:2020-08-26 00:00:00

  • The Different Microbial Etiology of Prosthetic Joint Infections according to Route of Acquisition and Time after Prosthesis Implantation, Including the Role of Multidrug-Resistant Organisms.

    abstract::The aim of our study was to characterize the etiology of prosthetic joint infections (PJIs)-including multidrug-resistant organisms (MDRO)-by category of infection. A multicenter study of 2544 patients with PJIs was performed. We analyzed the causative microorganisms according to the Tsukayama's scheme (early postoper...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8050673

    authors: Benito N,Mur I,Ribera A,Soriano A,Rodríguez-Pardo D,Sorlí L,Cobo J,Fernández-Sampedro M,Del Toro MD,Guío L,Praena J,Bahamonde A,Riera M,Esteban J,Baraia-Etxaburu JM,Martínez-Alvarez J,Jover-Sáenz A,Dueñas C,Ramos A,

    更新日期:2019-05-13 00:00:00

  • Meta-Analysis: Urinary Calprotectin for Discrimination of Intrinsic and Prerenal Acute Kidney Injury.

    abstract::Background: Urinary calprotectin is a novel biomarker that distinguishes between intrinsic or prerenal acute kidney injury (AKI) in different studies. However, these studies were based on different populations and different AKI criteria. We evaluated the diagnostic accuracy of urinary calprotectin and compared its dia...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm8010074

    authors: Chen JJ,Fan PC,Kou G,Chang SW,Chen YT,Lee CC,Chang CH

    更新日期:2019-01-10 00:00:00

  • On Cancer, COVID-19, and CT Scans: A Monocentric Retrospective Study.

    abstract::Background The use of computed tomography (CT) for coronavirus disease 2019 (COVID-19) diagnosis in an area of northern Italy with a high incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may have identified more patients with this disease than RT-PCR in the very early onset of the CO...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9123935

    authors: Martini F,D'Alessio A,Bracchi F,Di Mauro D,Fargnoli A,Motta M,Giussani C,Meazza Prina M,Gobbin G,Taverna M

    更新日期:2020-12-04 00:00:00

  • Hypovitaminosis D Influences the Clinical Presentation of Immune Thrombocytopenia in Children with Newly Diagnosed Disease.

    abstract::Immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by isolated thrombocytopenia defined as platelet count in peripheral blood <100 × 109/L. Hypovitaminosis D is very common in children with autoimmune diseases. To analyze whether hypovitaminosis D is associated with the clinical presentatio...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8111861

    authors: Petrovic D,Benzon B,Batinic M,Culic S,Roganovic J,Markic J

    更新日期:2019-11-03 00:00:00

  • Cardiovascular Events throughout the Disease Course in Chronic Myeloid Leukaemia Patients Treated with Tyrosine Kinase Inhibitors-A Single-Centre Retrospective Study.

    abstract:INTRODUCTION:Cardiovascular risk factors, pre-existing comorbidities, molecular factors, and the direct effects of second- and third-generation BCR-ABL1 tyrosine kinase inhibitors on the vascular endothelium contribute to the progression of cardiovascular (CV) events, especially atherothrombotic conditions. The study o...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9103269

    authors: Varga A,Tilea I,Petra DN,Tilinca MC,Gliga ML,Demian S

    更新日期:2020-10-12 00:00:00

  • Repurposing Immunomodulatory Therapies against Coronavirus Disease 2019 (COVID-19) in the Era of Cardiac Vigilance: A Systematic Review.

    abstract::The ongoing coronavirus disease 2019 (COVID-19) pandemic has resulted in efforts to identify therapies to ameliorate adverse clinical outcomes. The recognition of the key role for increased inflammation in COVID-19 has led to a proliferation of clinical trials targeting inflammation. The purpose of this review is to c...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm9092935

    authors: Campbell CM,Guha A,Haque T,Neilan TG,Addison D

    更新日期:2020-09-11 00:00:00

  • The Diagnostic Accuracy of Magnetic Resonance Imaging for Maternal Acute Adnexal Torsion during Pregnancy: Single-Institution Clinical Performance Review.

    abstract:BACKGROUND:For acute adnexal torsion of pregnant women, appropriate treatment based on an accurate diagnosis is especially important for fertility preservation and timely treatment. The 2017 American College of Obstetricians and Gynecologists (ACOG) Committee Opinion No. 723 announced its practice-changing guidelines t...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9072209

    authors: Lee JH,Roh HJ,Ahn JW,Kim JS,Choi JY,Lee SJ,Lee SH

    更新日期:2020-07-13 00:00:00

  • Factors Associated with Decisions for Initial Dosing, Up-Titration of Propiverine and Treatment Outcomes in Overactive Bladder Syndrome Patients in a Non-Interventional Setting.

    abstract::Two doses of propiverine ER (30 and 45 mg/d) are available for the treatment of overactive bladder (OAB) syndrome. We have explored factors associated with the initial dosing choice (allocation bias), the decision to adapt dosing (escalation bias) and how dosing relative to other factors affects treatment outcomes. Da...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm10020311

    authors: Amiri M,Schneider T,Oelke M,Murgas S,Michel MC

    更新日期:2021-01-15 00:00:00

  • The Lipid Status in Patients with Ulcerative Colitis: Sphingolipids are Disease-Dependent Regulated.

    abstract::The factors that contribute to the development of ulcerative colitis (UC), are still not fully identified. Disruption of the colon barrier is one of the first events leading to invasion of bacteria and activation of the immune system. The colon barrier is strongly influenced by sphingolipids. Sphingolipids impact cell...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8070971

    authors: Bazarganipour S,Hausmann J,Oertel S,El-Hindi K,Brachtendorf S,Blumenstein I,Kubesch A,Sprinzl K,Birod K,Hahnefeld L,Trautmann S,Thomas D,Herrmann E,Geisslinger G,Schiffmann S,Grösch S

    更新日期:2019-07-04 00:00:00

  • Metabolomic Profiles Predict Diabetes Remission after Bariatric Surgery.

    abstract:BACKGROUND:Amino acid metabolites (AAMs) have been linked to glucose homeostasis and type 2 diabetes (T2D). We investigated whether (1) baseline AAMs predict T2D remission 12 months after bariatric surgery and (2) whether AAMs are superior for predicting T2D remission postoperatively compared with existing prediction m...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9123897

    authors: Ha J,Jang M,Kwon Y,Park YS,Park DJ,Lee JH,Lee HJ,Ha TK,Kim YJ,Han SM,Han SU,Heo Y,Park S

    更新日期:2020-12-01 00:00:00

  • The Emperor Has No Clothes? Searching for Dysregulation in Sepsis.

    abstract::The core conception of sepsis-that it is a dysregulated state-is a powerful and durable idea that has inspired decades of research. But is it true that the body's response to sepsis is dysregulated? To answer that question, this review surveyed the history of trials of experimental sepsis treatments targeting the host...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm7090247

    authors: Alcock J

    更新日期:2018-08-29 00:00:00

  • Usefulness of P Wave Duration in Embolic Stroke of Undetermined Source.

    abstract::The investigation of the potential association between ischemic stroke and subclinical atrial fibrillation (SCAF) is important for secondary prevention. We aimed to determine whether SCAF can be predicted by atrial substrate measurement with P wave signal-averaged electrocardiography (SAECG). We recruited 125 consecut...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9041134

    authors: Jung M,Kim JS,Song JH,Kim JM,Park KY,Lee WS,Kim SW,Lip GY,Shin SY

    更新日期:2020-04-15 00:00:00

  • Brace Treatment for Adolescent Idiopathic Scoliosis.

    abstract::In the past, numerous non-operative treatments for adolescent idiopathic scoliosis (AIS), including exercise, physical therapy, electrical stimulation, and brace treatment, have been tried to delay or prevent the curve progression. Of these, brace treatment is the only option that is widely accepted and has demonstrat...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm7060136

    authors: Kuroki H

    更新日期:2018-06-04 00:00:00

  • Clinical Response and Changes of Cytokines and Zonulin Levels in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Treated with Bifidobacterium Longum ES1 for 8 or 12 Weeks: A Preliminary Report.

    abstract::Bifidobacterium longum (B. longum) ES1 is a probiotic strain capable of modulating microbiome composition, anti-inflammatory activity and intestinal barrier function. We investigated the use of B. Longum ES1 in the treatment of patients with diarrhoea-predominant irritable bowel syndrome (IBS-D). Sixteen patients were...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9082353

    authors: Caviglia GP,Tucci A,Pellicano R,Fagoonee S,Rosso C,Abate ML,Olivero A,Armandi A,Vanni E,Saracco GM,Bugianesi E,Astegiano M,Ribaldone DG

    更新日期:2020-07-23 00:00:00

  • Pulmonary Vein Enlargement as an Independent Predictor for New-Onset Atrial Fibrillation.

    abstract::Pulmonary vein (PV) enlargement is associated with atrial fibrillation (AF). However, the predictive value of PV volume for new-onset AF has not been determined. We retrospectively assessed and enrolled non-AF subjects who underwent echocardiography and cardiac CT angiography (CCTA) around the same time and evaluated ...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9020401

    authors: Kim S,Kim YH,Lee SH,Kim JS

    更新日期:2020-02-02 00:00:00

  • DJ-1 in Parkinson's Disease: Clinical Insights and Therapeutic Perspectives.

    abstract::Mutations in the protein DJ-1 cause autosomal recessive forms of Parkinson's disease (PD) and oxidized DJ-1 is found in the brains of idiopathic PD individuals. While several functions have been ascribed to DJ-1 (most notably protection from oxidative stress), its contribution to PD pathogenesis is not yet clear. Here...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm8091377

    authors: Repici M,Giorgini F

    更新日期:2019-09-03 00:00:00

  • Couple Relationship and Parent-Child Relationship Quality: Factors Relevant to Parent-Child Communication on Sexuality in Romania.

    abstract::This study of parents in Romania explores how perceptions of their couple relationship quality and of factors associated with it (such as sexual communication anxiety and sexual perfectionism) were related to their perception of aspects describing parenting dimensions relevant to the sexual education and sexual health...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8030386

    authors: Pop MV,Rusu AS

    更新日期:2019-03-19 00:00:00

  • Why Have Detection, Understanding and Management of Kidney Hypoxic Injury Lagged Behind those for the Heart?

    abstract::The outcome of patients with acute myocardial infarction (AMI) has dramatically improved over recent decades, thanks to early detection and prompt interventions to restore coronary blood flow. In contrast, the prognosis of patients with hypoxic acute kidney injury (AKI) remained unchanged over the years. Delayed diagn...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8020267

    authors: Abassi Z,Rosen S,Lamothe S,Heyman SN

    更新日期:2019-02-21 00:00:00

  • The Power and the Promise of Cell Reprogramming: Personalized Autologous Body Organ and Cell Transplantation.

    abstract::Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) or direct reprogramming to desired cell types are powerful and new in vitro methods for the study of human disease, cell replacement therapy, and drug development. Both methods to reprogram cells are unconstrained by the ethical and social questions...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm3020373

    authors: Palomo AB,Lucas M,Dilley RJ,McLenachan S,Chen FK,Requena J,Sal MF,Lucas A,Alvarez I,Jaraquemada D,Edel MJ

    更新日期:2014-04-04 00:00:00

  • The New ELN Recommendations for Treating CML.

    abstract::After normal survival has been achieved in most patients with chronic myeloid leukemia (CML), a new goal for treating CML is survival at good quality of life, with treatment discontinuation in sustained deep molecular response (DMR; MR4 or deeper) and treatment-free remission (TFR). Four tyrosine kinase inhibitors (TK...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm9113671

    authors: Hehlmann R

    更新日期:2020-11-16 00:00:00

  • Simplified Diagnosis of Critical Illness Polyneuropathy in Patients with Prolonged Mechanical Ventilation: A Prospective Observational Cohort Study.

    abstract:BACKGROUND:Although early identification of critical illness polyneuropathy (CIP) is necessary, the established diagnostic criteria have several limitations in the intensive care unit (ICU) setting. The purpose of this study was to define simplified diagnostic criteria of CIP that best predict clinical outcomes. METHO...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9124029

    authors: Jung C,Choi NJ,Kim WJ,Chun YM,Lee HJ,Kim TH,Pak SR,Lee JH,Hong SK,Kim W

    更新日期:2020-12-13 00:00:00

  • Ovarian Cancer in the Elderly: Time to Move towards a More Logical Approach to Improve Prognosis-A Study from the FRANCOGYN Group.

    abstract:BACKGROUND AND OBJECTIVE:Elderly and/or frail women with ovarian cancer are often undertreated. The aim of the study is to compare the effects of age and frailty on surgical approaches, postoperative complications, and prognosis in elderly women with ovarian cancer. METHODS:A retrospective multicenter study of women ≥...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9051339

    authors: Dion L,Mimoun C,Nyangoh Timoh K,Bendifallah S,Bricou A,Collinet P,Touboul C,Ouldamer L,Azaïs H,Dabi Y,Akladios C,Canlorbe G,Bolze PA,Costaz H,Mezzadri M,Gauthier T,Kridelka F,Chauvet P,Bourdel N,Koskas M,Carcopino

    更新日期:2020-05-04 00:00:00

  • Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy.

    abstract::Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare autosomal recessive disorder of nucleoside metabolism that is caused by mutations in the nuclear thymidine phosphorylase gene (TYMP) gene, encoding for the enzyme thymidine phosphorylase. There are currently no approved treatments for MNGIE...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm8040457

    authors: Levene M,Bain MD,Moran NF,Nirmalananthan N,Poulton J,Scarpelli M,Filosto M,Mandel H,MacKinnon AD,Fairbanks L,Pacitti D,Bax BE

    更新日期:2019-04-05 00:00:00

  • New Molecular Technologies for Minimal Residual Disease Evaluation in B-Cell Lymphoid Malignancies.

    abstract::The clearance of malignant clonal cells significantly correlates with clinical outcomes in many hematologic malignancies. Accurate and high throughput tools for minimal residual disease (MRD) detection are needed to overcome some drawbacks of standard molecular techniques; such novel tools have allowed for higher sens...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm7090288

    authors: Dogliotti I,Drandi D,Genuardi E,Ferrero S

    更新日期:2018-09-18 00:00:00

  • Diabetic Nephropathy and CKD-Analysis of Individual Patient Serum Creatinine Trajectories: A Forgotten Diagnostic Methodology for Diabetic CKD Prognostication and Prediction.

    abstract::Creatinine is produced in muscle metabolism as the end-product of creatine phosphate and is subsequently excreted principally by way of the kidneys, predominantly by glomerular filtration. Blood creatinine assays constitute the most common clinically relevant measure of renal function. The use of individual patient-le...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章,评审

    doi:10.3390/jcm4071348

    authors: Onuigbo MA,Agbasi N

    更新日期:2015-06-26 00:00:00

  • Surgical Treatment on Subungual Osteochondromas in Paediatric Feet: A Case Series Study.

    abstract::Subungual osteochondroma (SO) is an infrequent and non-malignant bone tumour of the distal phalanx, especially prominent in paediatric populations. The aim of this research was to describe a case series of paediatric feet with SO which received surgical treatments. The secondary purpose was to compare these descriptiv...

    journal_title:Journal of clinical medicine

    pub_type: 杂志文章

    doi:10.3390/jcm9041122

    authors: Navarro-Flores E,López-López D,Becerro-de-Bengoa-Vallejo R,Losa-Iglesias ME,Romero-Morales C,San-Antolín-Gil M,Calvo-Lobo C,Bautista-Casasnovas AL

    更新日期:2020-04-14 00:00:00

  • Oxidative Stress in COPD.

    abstract::Numerous studies over the years have shown that oxidative stress plays a major role in the development of the disease. Oxidative stress involvement in COPD opens up the possibility of using antioxidant therapies in the treatment of the disease. However, so far, these therapies have shown no clinical benefit indicating...

    journal_title:Journal of clinical medicine

    pub_type: 社论

    doi:10.3390/jcm8111953

    authors: Magallón M,Navarro-García MM,Dasí F

    更新日期:2019-11-13 00:00:00