Abstract:
:High-quality data on funding for mental health research are essential to mapping funding levels, identifying gaps in the funding landscape, and tracking the impact of research funding. To date, quantitative analyses of research funding in mental health have been restricted in scope. In this Health Policy paper, we present a comprehensive analysis of grant funding for mental health research as a starting point for discussion among stakeholders globally. We drew on a major international research database and used existing definitions and automated classification tools for mental health research. Our analysis shows a flat and stable trend over the years 2015-19 and highly unequal geographical distribution of funding, and reveals patterns of funding across different conditions and across the research spectrum. Improvements in data availability and quality, in the definitions delineating mental health research from other areas, and in automated classification tools are needed to ensure funders and policy makers can fully rely on the data and generate bespoke analyses as needed. We argue that collaborative reporting of funding for mental health research globally could help to inform and evaluate efforts to increase investments, to improve strategic dialogue, and to achieve the best possible allocation of finite resources.
journal_name
Lancet Psychiatryjournal_title
The lancet. Psychiatryauthors
Woelbert E,Lundell-Smith K,White R,Kemmer Ddoi
10.1016/S2215-0366(20)30469-7subject
Has Abstractpub_date
2020-11-23 00:00:00eissn
2215-0366issn
2215-0374pii
S2215-0366(20)30469-7pub_type
杂志文章,评审abstract:BACKGROUND:Social anxiety disorder-a chronic and naturally unremitting disease that causes substantial impairment-can be treated with pharmacological, psychological, and self-help interventions. We aimed to compare these interventions and to identify which are most effective for the acute treatment of social anxiety di...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(14)70329-3
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Exercise is known to be associated with reduced risk of all-cause mortality, cardiovascular disease, stroke, and diabetes, but its association with mental health remains unclear. We aimed to examine the association between exercise and mental health burden in a large sample, and to better understand the infl...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(18)30227-X
更新日期:2018-09-01 00:00:00
abstract::Contemporary psychiatry faces major challenges. Its syndrome-based disease classification is not based on mechanisms and does not guide treatment, which largely depends on trial and error. The development of therapies is hindered by ignorance of potential beneficiary patient subgroups. Neuroscientific and genetics res...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(15)00361-2
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Self-harm is the strongest risk factor for subsequent suicide, but risk may vary. We compared the risk of suicide following hospital presentation for self-harm according to patient characteristics, method of self-harm, and variations in area-level socioeconomic deprivation, and estimated the incidence of sui...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1016/S2215-0366(19)30402-X
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Housing First is increasingly implemented for homeless adults with mental illness in large urban centres, but little is known about its long-term effectiveness. The At Home/Chez Soi randomised controlled trial done in five cities in Canada showed that Housing First improved housing stability and other select...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/S2215-0366(19)30371-2
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Suicidal ideation due to abortion has been used to justify restrictive US abortion policies. Much research examining abortion and mental health has relied on self-report, has had low participation rates, and did not consider confounding factors. In the present study, we used data that do not rely on self-rep...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(19)30400-6
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:The conceptualisation of transgender identity as a mental disorder has contributed to precarious legal status, human rights violations, and barriers to appropriate health care among transgender people. The proposed reconceptualisation of categories related to transgender identity in WHO's forthcoming Interna...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(16)30165-1
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:In high-income countries, maternal postnatal depression is associated with adverse outcomes in the child. However, few studies have investigated this relation in countries of low and middle income. Furthermore, to our knowledge, no studies have followed up cohorts into later childhood. We aimed to investigat...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(14)70361-X
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Self-harm in adolescents is common and repetition occurs in a high proportion of these cases. Scarce evidence exists for effectiveness of interventions to reduce self-harm. METHODS:This pragmatic, multicentre, randomised, controlled trial of family therapy versus treatment as usual was done at 40 UK Child a...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/S2215-0366(18)30058-0
更新日期:2018-03-01 00:00:00
abstract::Nutritional psychiatry is a growing area of research, with several nutritional factors implicated in the cause of psychiatric ill-health. However, nutritional research is highly complex, with multiple potential factors involved, highly confounded exposures and small effect sizes for individual nutrients. This Personal...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(19)30293-7
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Compulsory community treatment (CCT) aims to reduce hospital readmissions among people with mental illness. However, research examining the usefulness of CCT is inconclusive. We aimed to assess the effectiveness of CCT in reducing readmission and length of stay in hospital and increasing community service us...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,meta分析
doi:10.1016/S2215-0366(18)30382-1
更新日期:2018-12-01 00:00:00
abstract::Neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder, although most commonly considered in childhood, can be lifelong conditions. In this Personal View that is shaped by clinical experience and research, we adopt a conceptual approach. First, we discuss what...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(16)30376-5
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Statins have shown both protective and adverse associations with neuropsychiatric outcomes. We aimed to examine the possible associations between statins and suicidality, depression, anxiety, and seizures. METHODS:Using Swedish national registers, we linked data on dispensed statin prescriptions with data o...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(20)30311-4
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Many clinical trials have assessed treatments for depressive disorders and bipolar depression. However, whether, and which, assessed outcome domains really matter to patients, informal caregivers, and health-care professionals remains unclear. METHODS:We did an international online survey in French, German,...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(20)30191-7
更新日期:2020-08-01 00:00:00
abstract::Autism spectrum conditions comprise a set of early-onset neurodevelopmental syndromes with a prevalence of 1% across all ages. First diagnosis in adulthood has finally become recognised as an important clinical issue due to the increasing awareness of autism, broadening of diagnostic criteria, and the introduction of ...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(15)00277-1
更新日期:2015-11-01 00:00:00
abstract::Cannabis use and related problems are on the rise globally alongside an increase in the potency of cannabis sold on both black and legal markets. Additionally, there has been a shift towards abandoning prohibition for a less punitive and more permissive legal stance on cannabis, such as decriminalisation and legalisat...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(17)30075-5
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Several small studies suggest that the adjunctive use of anti-inflammatory agents might improve depressive symptoms in bipolar disorder. However, there are few well designed, appropriately powered clinical trials assessing the efficacy of these novel treatment strategies. We aimed to assess the efficacy of a...
journal_title:The lancet. Psychiatry
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/S2215-0366(20)30138-3
更新日期:2020-06-01 00:00:00
abstract::The ubiquitin-proteasome system is a master regulator of neural development and the maintenance of brain structure and function. It influences neurogenesis, synaptogenesis, and neurotransmission by determining the localisation, interaction, and turnover of scaffolding, presynaptic, and postsynaptic proteins. Moreover,...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(19)30520-6
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Adults with intellectual disabilities have substantial health inequalities and poor access to health care. We assessed whether practice nurse-delivered health checks could improve the health of adults with intellectual disabilities compared with standard care. METHODS:In this cluster-design, single-blind, r...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(14)00078-9
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Many people with dementia living in care homes have distressing and costly agitation symptoms. Interventions should be efficacious, scalable, and feasible. METHODS:We did a parallel-group, cluster-randomised controlled trial in 20 care homes across England. Care homes were eligible if they had 17 residents ...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/S2215-0366(19)30045-8
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Although clozapine is the treatment of choice for treatment-refractory schizophrenia, 30-40% of patients have an insufficient response, and others are unable to tolerate it. Evidence for any augmentation strategies is scarce. We aimed to determine whether cognitive behavioural therapy (CBT) is an effective t...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/S2215-0366(18)30184-6
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Use of involuntary psychiatric hospitalisation varies widely within and between countries. The factors that place individuals and populations at increased risk of involuntary hospitalisation are unclear, and evidence is needed to understand these disparities and inform development of interventions to reduce ...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,meta分析
doi:10.1016/S2215-0366(19)30406-7
更新日期:2019-12-01 00:00:00
abstract::The unpredictability and uncertainty of the COVID-19 pandemic; the associated lockdowns, physical distancing, and other containment strategies; and the resulting economic breakdown could increase the risk of mental health problems and exacerbate health inequalities. Preliminary findings suggest adverse mental health e...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(20)30307-2
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Late-life depressive symptoms have been extensively studied for their relationship with incident dementia, but have been typically assessed at a single timepoint. Such an approach neglects the course of depression, which, given its remitting and relapsing nature, might provide further insights into the compl...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章
doi:10.1016/S2215-0366(16)00097-3
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Substantial evidence suggests that cognitive deficits might persist after remission of a major depressive episode. However, results are inconsistent relative to the importance, pattern, severity, and moderating factors of this impairment. We aimed to determine how cognitive function following a major depress...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,meta分析
doi:10.1016/S2215-0366(19)30291-3
更新日期:2019-10-01 00:00:00
abstract::A spectrum of severity of paranoia (unfounded thoughts that others are deliberately intending to cause harm) exists within the general population. This is unsurprising: deciding whether to trust or mistrust is a vital aspect of human cognition, but accurate judgment of others' intentions is challenging. The severest f...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(16)00066-3
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Early social deprivation can negatively affect domains of functioning. We examined psychopathology at age 12 years in a cohort of Romanian children who had been abandoned at birth and placed into institutional care, then assigned either to be placed in foster care or to care as usual. METHODS:We used follow...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1016/S2215-0366(15)00095-4
更新日期:2015-07-01 00:00:00
abstract::The aim of this Review is to identify effective interventions and treatment guidelines to manage common types of psychiatric emergencies in non-specialist settings in low-income and middle-income countries. Mental health specialist services in low-income and middle-income countries are scarce. We did a systematic revi...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(15)00094-2
更新日期:2015-06-01 00:00:00
abstract::Over the past decade, concussion has become the most widely discussed injury in contact sports. However, concussions also occur in several other settings, such as non-contact sports, elderly individuals, young children, military personnel, and victims of domestic violence. Concussion is frequently undiagnosed as a cau...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(16)30266-8
更新日期:2016-12-01 00:00:00
abstract::Substance use in young people (aged 10-24 years) might disrupt key periods of transition that occur as the adolescent brain undergoes cognitive and emotional development, and key psychosocial transitions are made. Adolescence is the peak time for initiation of substance use, with tobacco and alcohol usually preceding ...
journal_title:The lancet. Psychiatry
pub_type: 杂志文章,评审
doi:10.1016/S2215-0366(15)00508-8
更新日期:2016-03-01 00:00:00