Mendelian randomisation for nutritional psychiatry.

abstract：BACKGROUND:Suicidal ideation due to abortion has been used to justify restrictive US abortion policies. Much research examining abortion and mental health has relied on self-report, has had low participation rates, and did not consider confounding factors. In the present study, we used data that do not rely on self-rep...

journal_title：The lancet. Psychiatry

authors： Steinberg JR,Laursen TM,Adler NE,Gasse C,Agerbo E,Munk-Olsen T

更新日期：2019-12-01 00:00:00

abstract：:The ubiquitin-proteasome system is a master regulator of neural development and the maintenance of brain structure and function. It influences neurogenesis, synaptogenesis, and neurotransmission by determining the localisation, interaction, and turnover of scaffolding, presynaptic, and postsynaptic proteins. Moreover,...

journal_title：The lancet. Psychiatry

authors： Luza S,Opazo CM,Bousman CA,Pantelis C,Bush AI,Everall IP

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Many studies suggest that electroencephalographic (EEG) neurofeedback might be beneficial in the treatment of attention-deficit hyperactivity disorder (ADHD). However, numbers of well controlled studies are low and neurofeedback techniques are regarded as highly controversial. The present trial examined the ...

journal_title：The lancet. Psychiatry

authors： Schönenberg M,Wiedemann E,Schneidt A,Scheeff J,Logemann A,Keune PM,Hautzinger M

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Cognitive behaviour therapy (CBT) added to specialist medical care (SMC), or graded exercise therapy (GET) added to SMC, are more effective in reducing fatigue and improving physical function than both adaptive pacing therapy (APT) plus SMC and SMC alone for chronic fatigue syndrome. We investigate putative ...

journal_title：The lancet. Psychiatry

authors： Chalder T,Goldsmith KA,White PD,Sharpe M,Pickles AR

更新日期：2015-02-01 00:00:00

abstract：:Cannabis use and related problems are on the rise globally alongside an increase in the potency of cannabis sold on both black and legal markets. Additionally, there has been a shift towards abandoning prohibition for a less punitive and more permissive legal stance on cannabis, such as decriminalisation and legalisat...

journal_title：The lancet. Psychiatry

authors： Englund A,Freeman TP,Murray RM,McGuire P

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The conceptualisation of transgender identity as a mental disorder has contributed to precarious legal status, human rights violations, and barriers to appropriate health care among transgender people. The proposed reconceptualisation of categories related to transgender identity in WHO's forthcoming Interna...

journal_title：The lancet. Psychiatry

authors： Robles R,Fresán A,Vega-Ramírez H,Cruz-Islas J,Rodríguez-Pérez V,Domínguez-Martínez T,Reed GM

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Anxiety in children is common, impairs everyday functioning, and increases the risk of severe mental health disorders in adulthood. We investigated the effect of a classroom-based cognitive behaviour therapy prevention programme (FRIENDS) on anxiety symptoms in children. METHODS:Preventing Anxiety in Childr...

journal_title：The lancet. Psychiatry

authors： Stallard P,Skryabina E,Taylor G,Phillips R,Daniels H,Anderson R,Simpson N

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Although clozapine is the treatment of choice for treatment-refractory schizophrenia, 30-40% of patients have an insufficient response, and others are unable to tolerate it. Evidence for any augmentation strategies is scarce. We aimed to determine whether cognitive behavioural therapy (CBT) is an effective t...

journal_title：The lancet. Psychiatry

authors： Morrison AP,Pyle M,Gumley A,Schwannauer M,Turkington D,MacLennan G,Norrie J,Hudson J,Bowe SE,French P,Byrne R,Syrett S,Dudley R,McLeod HJ,Griffiths H,Barnes TRE,Davies L,Kingdon D,FOCUS trial group.

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Exercise is known to be associated with reduced risk of all-cause mortality, cardiovascular disease, stroke, and diabetes, but its association with mental health remains unclear. We aimed to examine the association between exercise and mental health burden in a large sample, and to better understand the infl...

journal_title：The lancet. Psychiatry

authors： Chekroud SR,Gueorguieva R,Zheutlin AB,Paulus M,Krumholz HM,Krystal JH,Chekroud AM

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Housing First is increasingly implemented for homeless adults with mental illness in large urban centres, but little is known about its long-term effectiveness. The At Home/Chez Soi randomised controlled trial done in five cities in Canada showed that Housing First improved housing stability and other select...

journal_title：The lancet. Psychiatry

authors： Stergiopoulos V,Mejia-Lancheros C,Nisenbaum R,Wang R,Lachaud J,O'Campo P,Hwang SW

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The definition of post-traumatic stress disorder (PTSD) underwent substantial changes in the 2013 edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). How this will affect estimates of prevalence, whether clinical utility has been improved, and how many individuals who meet symptom c...

journal_title：The lancet. Psychiatry

authors： Hoge CW,Riviere LA,Wilk JE,Herrell RK,Weathers FW

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:In view of the high co-occurrence of depression and insomnia, a novel way to reduce the risk of escalating depression might be to offer an insomnia intervention. We aimed to assess whether an online self-help insomnia program could reduce depression symptoms. METHODS:We did this randomised controlled trial ...

journal_title：The lancet. Psychiatry

authors： Christensen H,Batterham PJ,Gosling JA,Ritterband LM,Griffiths KM,Thorndike FP,Glozier N,O'Dea B,Hickie IB,Mackinnon AJ

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Substantial evidence suggests that cognitive deficits might persist after remission of a major depressive episode. However, results are inconsistent relative to the importance, pattern, severity, and moderating factors of this impairment. We aimed to determine how cognitive function following a major depress...

journal_title：The lancet. Psychiatry

authors： Semkovska M,Quinlivan L,O'Grady T,Johnson R,Collins A,O'Connor J,Knittle H,Ahern E,Gload T

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Many older adults with major depression, particularly veterans, do not have access to evidence-based psychotherapy. Telemedicine could increase access to best-practice care for older adults facing barriers of mobility, stigma, and geographical isolation. We aimed to establish non-inferiority of behavioural a...

journal_title：The lancet. Psychiatry

authors： Egede LE,Acierno R,Knapp RG,Lejuez C,Hernandez-Tejada M,Payne EH,Frueh BC

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Use of involuntary psychiatric hospitalisation varies widely within and between countries. The factors that place individuals and populations at increased risk of involuntary hospitalisation are unclear, and evidence is needed to understand these disparities and inform development of interventions to reduce ...

journal_title：The lancet. Psychiatry

authors： Walker S,Mackay E,Barnett P,Sheridan Rains L,Leverton M,Dalton-Locke C,Trevillion K,Lloyd-Evans B,Johnson S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:People living in group situations or with dementia are more vulnerable to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Older people and those with multimorbidity have higher mortality if they become infected than the general population. However, no systematic study exists of C...

journal_title：The lancet. Psychiatry

authors： Livingston G,Rostamipour H,Gallagher P,Kalafatis C,Shastri A,Huzzey L,Liu K,Sommerlad A,Marston L

更新日期：2020-12-01 00:00:00

abstract：:South Africa witnessed a national tragedy between October, 2015, and June, 2016, when the Department of Health in Gauteng province moved 1711 mental health-care users with severe mental illness or severe and profound intellectual disability out of facilities managed by a private company, Life Esidimeni, mainly into th...

journal_title：The lancet. Psychiatry

authors： Freeman MC

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Statins have shown both protective and adverse associations with neuropsychiatric outcomes. We aimed to examine the possible associations between statins and suicidality, depression, anxiety, and seizures. METHODS:Using Swedish national registers, we linked data on dispensed statin prescriptions with data o...

journal_title：The lancet. Psychiatry

authors： Molero Y,Cipriani A,Larsson H,Lichtenstein P,D'Onofrio BM,Fazel S

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Many people with dementia living in care homes have distressing and costly agitation symptoms. Interventions should be efficacious, scalable, and feasible. METHODS:We did a parallel-group, cluster-randomised controlled trial in 20 care homes across England. Care homes were eligible if they had 17 residents ...

journal_title：The lancet. Psychiatry

authors： Livingston G,Barber J,Marston L,Stringer A,Panca M,Hunter R,Cooper C,Laybourne A,La Frenais F,Reeves S,Manela M,Lambe K,Banerjee S,Rapaport P

更新日期：2019-04-01 00:00:00

abstract：:More than 10 million people are imprisoned worldwide, and the prevalence of all investigated mental disorders is higher in prisoners than in the general population. Although the extent to which prison increases the incidence of mental disorders is uncertain, considerable evidence suggests low rates of identification a...

journal_title：The lancet. Psychiatry

authors： Fazel S,Hayes AJ,Bartellas K,Clerici M,Trestman R

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Self-harm is the strongest risk factor for subsequent suicide, but risk may vary. We compared the risk of suicide following hospital presentation for self-harm according to patient characteristics, method of self-harm, and variations in area-level socioeconomic deprivation, and estimated the incidence of sui...

journal_title：The lancet. Psychiatry

authors： Geulayov G,Casey D,Bale L,Brand F,Clements C,Farooq B,Kapur N,Ness J,Waters K,Tsiachristas A,Hawton K

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:There is major concern about the impact of the global COVID-19 outbreak on mental health. Several studies suggest that mental health deteriorated in many countries before and during enforced isolation (ie, lockdown), but it remains unknown how mental health has changed week by week over the course of the COV...

journal_title：The lancet. Psychiatry

authors： Fancourt D,Steptoe A,Bu F

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Compulsory community treatment (CCT) aims to reduce hospital readmissions among people with mental illness. However, research examining the usefulness of CCT is inconclusive. We aimed to assess the effectiveness of CCT in reducing readmission and length of stay in hospital and increasing community service us...

journal_title：The lancet. Psychiatry

authors： Barnett P,Matthews H,Lloyd-Evans B,Mackay E,Pilling S,Johnson S

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Long-standing concerns exist about reverse causation and residual confounding in the prospective association between job strain and risk of future common mental disorders. We aimed to address these concerns through analysis of data collected in the UK National Child Development Study, a large British cohort ...

journal_title：The lancet. Psychiatry

authors： Harvey SB,Sellahewa DA,Wang MJ,Milligan-Saville J,Bryan BT,Henderson M,Hatch SL,Mykletun A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Self-harm in adolescents is common and repetition occurs in a high proportion of these cases. Scarce evidence exists for effectiveness of interventions to reduce self-harm. METHODS:This pragmatic, multicentre, randomised, controlled trial of family therapy versus treatment as usual was done at 40 UK Child a...

journal_title：The lancet. Psychiatry

authors： Cottrell DJ,Wright-Hughes A,Collinson M,Boston P,Eisler I,Fortune S,Graham EH,Green J,House AO,Kerfoot M,Owens DW,Saloniki EC,Simic M,Lambert F,Rothwell J,Tubeuf S,Farrin AJ

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:In high-income countries, maternal postnatal depression is associated with adverse outcomes in the child. However, few studies have investigated this relation in countries of low and middle income. Furthermore, to our knowledge, no studies have followed up cohorts into later childhood. We aimed to investigat...

journal_title：The lancet. Psychiatry

authors： Verkuijl NE,Richter L,Norris SA,Stein A,Avan B,Ramchandani PG

更新日期：2014-11-01 00:00:00

abstract：:Autism spectrum conditions comprise a set of early-onset neurodevelopmental syndromes with a prevalence of 1% across all ages. First diagnosis in adulthood has finally become recognised as an important clinical issue due to the increasing awareness of autism, broadening of diagnostic criteria, and the introduction of ...

journal_title：The lancet. Psychiatry

authors： Lai MC,Baron-Cohen S

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Several small studies suggest that the adjunctive use of anti-inflammatory agents might improve depressive symptoms in bipolar disorder. However, there are few well designed, appropriately powered clinical trials assessing the efficacy of these novel treatment strategies. We aimed to assess the efficacy of a...

journal_title：The lancet. Psychiatry

authors： Husain MI,Chaudhry IB,Khoso AB,Husain MO,Hodsoll J,Ansari MA,Naqvi HA,Minhas FA,Carvalho AF,Meyer JH,Deakin B,Mulsant BH,Husain N,Young AH

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Late-life depressive symptoms have been extensively studied for their relationship with incident dementia, but have been typically assessed at a single timepoint. Such an approach neglects the course of depression, which, given its remitting and relapsing nature, might provide further insights into the compl...

journal_title：The lancet. Psychiatry

authors： Mirza SS,Wolters FJ,Swanson SA,Koudstaal PJ,Hofman A,Tiemeier H,Ikram MA

更新日期：2016-07-01 00:00:00

abstract：:Suicide is the 15th leading cause of death worldwide, with over 75% of suicides occurring in low-income and middle-income countries. Nonetheless, evidence on the association between suicide and poverty in low-income and middle-income countries is scarce. We did a systematic review to understand the association between...

journal_title：The lancet. Psychiatry

authors： Iemmi V,Bantjes J,Coast E,Channer K,Leone T,McDaid D,Palfreyman A,Stephens B,Lund C

更新日期：2016-08-01 00:00:00