Abstract:
:Pediatric cancer survivors are at increased risk for psychological distress. We sought to understand the severity and symptoms' co-occurrence among pediatric survivors compared to controls by rating both self- and parent-reported symptomatology. Forty survivors (22 males; mean age at study time: 12.9 years) participated in the study. Most survivors (85%) had a diagnosis of acute lymphoblastic leukemia. Seventy-nine healthy controls with the same age and gender distribution as the patients were included. A standardized assessment of psychological functioning was conducted by self- and parent-reported symptoms evaluations. The self-reported anxious symptom severity was significantly higher in survivors. A significantly higher proportion of survivors compared to controls had clinically significant anxiety, depression, and combined anxiety symptoms (i.e., social anxiety, separation anxiety, or physical symptoms). In both study groups, the self-reported emotional and somatic symptoms were significantly associated. The multi-informant assessments of the psychological symptoms revealed distinct associations between the child- and parent-reported symptoms in the survivors' group: the survivors' self-reports of depressive symptoms, somatic symptoms, and functional impairment were significantly correlated with the parent reports of child behavioral concerns, somatic complaints, and functional impairment, respectively. Conclusion: Self-reported symptoms showed similar comorbidity profiles in survivors and control peers. The multi-informant assessments detected differences in the association of self- and parent-reported symptoms between the survivor and control groups. The present study showed that multi-informant assessment is critical to understanding symptom profiles and to informing intervention with particular regard to parental participation and support.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Barone R,Gulisano M,Cannata E,Padalino S,Saia F,Maugeri N,Pettinato F,Lo Nigro L,Casabona A,Russo G,Di Cataldo A,Rizzo Rdoi
10.3390/jcm9113444subject
Has Abstractpub_date
2020-10-27 00:00:00issue
11issn
2077-0383pii
jcm9113444journal_volume
9pub_type
杂志文章abstract:BACKGROUND:Research findings regarding the association between tricyclic antidepressant (TCA) treatment and the risk of fracture are not consistent; we aimed to assess whether people who take TCAs are at an increased fracture risk. METHODS:Relevant studies published through June 2020 were identified through database s...
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pub_type: 杂志文章,评审
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更新日期:2020-08-10 00:00:00
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abstract::Since the discovery of the causal association between human papillomavirus (HPV) and cervical cancer, efforts to develop an effective prophylactic vaccine to prevent high-risk HPV infections have been at the forefront of modern medical research. HPV causes 530,000 cervical cancer cases worldwide, which is the second m...
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abstract::Current therapy of Clostridium difficile diarrhea (CDD) is problematic. Optimal treatment for CDD remains oral vancomycin, but there is little data on oral vancomycin dosing regimens. The objective of this C. difficile diarrhea study was to compare the efficacy of "high dose" vancomycin, 500 mg (PO) q6h, as sole treat...
journal_title:Journal of clinical medicine
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更新日期:2018-04-10 00:00:00
abstract::Liquid fibrinogen is an injectable platelet concentrate rich in platelets, leukocytes, and fibrinogen obtained by blood centrifugation. The aim of this study was to analyze the release of different growth factors in the liquid fibrinogen at different times and to assess possible correlations between growth factors and...
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abstract::Osteogenesis imperfecta (OI) is a connective tissue disorder that is characterized by low bone density leading to recurrent fractures. The efficacy of the anti-resorption drug denosumab for OI with osteoporosis is still largely unknown. We herein describe the clinical outcomes of eight osteoporotic cases of OI to exam...
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abstract::Acute kidney injury and renal failure are common after heart transplantation. We retrospectively reviewed a national cohort and identified 1129 heart transplant patients. Patients receiving renal replacement therapy after heart transplantation were grouped into the dialysis cohort. The long-term survival and risk fact...
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abstract::Patient-reported outcome measures (PROMs) are used to assess satisfaction after total hip arthroplasty (THA); however, the factors that determine these PROMs remain unclear. This study aimed to identify the patient- and surgery-related factors that affect patient satisfaction after THA as indicated by the Oxford Hip S...
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journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2020-09-14 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9030830
更新日期:2020-03-18 00:00:00
abstract::Postoperative complications after pancreatic surgery are still a significant problem in clinical practice. The aim of this study was to characterize and compare the microbiomes of different body compartments (bile duct, duodenal mucosa, pancreatic tumor lesion, postoperative drainage fluid, and stool samples; preopera...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2020-08-28 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm7020012
更新日期:2018-01-26 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2019-05-14 00:00:00
abstract::Fertility preservation in trans women is a crucial but thus far neglected component in the gender confirming treatment in Germany. It is difficult for trans women to access reproductive health care because centers offering treatment, psychological guidance, gender confirming surgery, as well as reproductive health ser...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm8050730
更新日期:2019-05-22 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9123796
更新日期:2020-11-24 00:00:00
abstract::Systemic sclerosis (SSc; scleroderma) is characterized by life-threatening progressive multiorgan fibrosis orchestrated by profibrotic myofibroblasts originating from different sources. Because recent data demonstrated that the majority of myofibroblasts in a murine scleroderma model arise from adipocytic progenitors ...
journal_title:Journal of clinical medicine
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doi:10.3390/jcm8081256
更新日期:2019-08-19 00:00:00
abstract::While satisfactory results have been reported during short-to mid-term follow-up assessments of hemophilic patients who have undergone total knee arthroplasty (TKA), limited literature focusing on long-term survival following TKA exists to date. As part of this investigation, a consecutive series of 78 TKAs in 56 pati...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2020-10-11 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2020-11-23 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2018-08-28 00:00:00
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journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2020-12-13 00:00:00
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更新日期:2019-12-29 00:00:00
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journal_title:Journal of clinical medicine
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更新日期:2021-01-09 00:00:00
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更新日期:2020-02-14 00:00:00
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journal_title:Journal of clinical medicine
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更新日期:2019-06-04 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2019-04-25 00:00:00