Change of Health-Related Quality of Life Over Time and Its Association With Patient Outcomes in Patients With Heart Failure.

abstract：BACKGROUND:MYBPC3 dysfunctions have been proven to induce dilated cardiomyopathy, hypertrophic cardiomyopathy, and/or left ventricular noncompaction; however, the genotype-phenotype correlation between MYBPC3 and restrictive cardiomyopathy (RCM) has not been established. The newly developed next-generation sequencing m...

journal_title：Journal of the American Heart Association

authors： Wu W,Lu CX,Wang YN,Liu F,Chen W,Liu YT,Han YC,Cao J,Zhang SY,Zhang X

更新日期：2015-07-10 00:00:00

abstract：BACKGROUND:NO bioavailability has not been systematically examined in congenital heart disease (CHD). To assess NO in patients with CHD, we measured nasal NO (nNO) generated by the nasal epithelia, given blood NO is difficult to measure (half-life, <2 ms). Given NO's role in hemodynamic regulation and the association o...

journal_title：Journal of the American Heart Association

authors： Adams PS,Zahid M,Khalifa O,Feingold B,Lo CW

更新日期：2017-12-06 00:00:00

abstract：:See Article Ramkumar et al. ...

journal_title：Journal of the American Heart Association

authors： Braun JD,Kougias P

更新日期：2019-09-03 00:00:00

abstract：:Background Low income and short education have been found to be independently associated with inferior survival after coronary artery bypass grafting (CABG), whereas the use of secondary prevention medications is associated with improved survival. We investigated whether underusage of secondary prevention medications ...

journal_title：Journal of the American Heart Association

authors： Nielsen SJ,Karlsson M,Björklund E,Martinsson A,Hansson EC,Malm CJ,Pivodic A,Jeppsson A

更新日期：2020-03-03 00:00:00

abstract：BACKGROUND:The intersection of heart failure (HF) and atrial fibrillation (AF) is common, but the burden of AF among black patients with HF is poorly characterized. We sought to determine the prevalence of AF, characteristics, in-hospital outcomes, and warfarin use associated with AF in patients hospitalized with HF as...

journal_title：Journal of the American Heart Association

authors： Thomas KL,Piccini JP,Liang L,Fonarow GC,Yancy CW,Peterson ED,Hernandez AF,Get With the Guidelines Steering Committee and Hospitals.

更新日期：2013-09-26 00:00:00

abstract：:Background Unruptured intracerebral aneurysm wall enhancement (AWE) on vessel wall magnetic resonance imaging scans may be a promising predictor for rupture-prone intracerebral aneurysms. However, the pathophysiology of AWE remains unclear. To this end, the association between AWE and histopathological changes was ass...

journal_title：Journal of the American Heart Association

authors： Zhong W,Su W,Li T,Tan X,Chen C,Wang Q,Wang D,Su W,Wang Y

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND:Whether the sympathetic nervous system can directly alter central aortic stiffness remains controversial, mainly because of the difficulty in experimentally augmenting peripheral vasoconstrictor activity without changing blood pressure. METHODS AND RESULTS:To address this limitation, we utilized low-level c...

journal_title：Journal of the American Heart Association

authors： Nardone M,Incognito AV,Millar PJ

更新日期：2018-01-29 00:00:00

abstract：:Background There are limited data about cardiac resynchronization therapy (CRT) in adult congenital heart disease. We aimed to assess early and late outcomes of CRT among patients with adult congenital heart disease. Methods and Results We retrospectively studied 54 patients with adult congenital heart disease (median...

journal_title：Journal of the American Heart Association

authors： Yin Y,Dimopoulos K,Shimada E,Lascelles K,Griffiths S,Wong T,Gatzoulis MA,Babu-Narayan SV,Li W

更新日期：2019-11-05 00:00:00

abstract：:Background Catheter ablation is an effective treatment for atrial fibrillation (AF), but high levels of post-procedure inflammation predict adverse clinical events. Ascorbic acid (AA) has shown promise in reducing inflammation but is untested in this population. We sought to test the feasibility, safety, and prelimina...

journal_title：Journal of the American Heart Association

authors： Trankle CR,Puckett L,Swift-Scanlan T,DeWilde C,Priday A,Sculthorpe R,Ellenbogen KA,Fowler A,Koneru JN

更新日期：2020-02-04 00:00:00

abstract：BACKGROUND:Diabetes is associated with coronary arteriolar endothelial dysfunction. We investigated the role of the small/intermediate (SK(Ca)/IK(Ca)) conductance of calcium-activated potassium channels in diabetes-related endothelial dysfunction. METHODS AND RESULTS:Coronary arterioles (80 to 150 μm in diameter) were...

journal_title：Journal of the American Heart Association

authors： Liu Y,Xie A,Singh AK,Ehsan A,Choudhary G,Dudley S,Sellke FW,Feng J

更新日期：2015-08-24 00:00:00

abstract：:Background Because systemic inflammation and endothelial dysfunction lead to heart failure with preserved ejection fraction, we characterized plasma levels of inflammatory and cardiac remodeling biomarkers in patients with Fabry disease ( FD ). Methods and Results Plasma biomarkers were studied in multicenter cohorts ...

journal_title：Journal of the American Heart Association

authors： Yogasundaram H,Nikhanj A,Putko BN,Boutin M,Jain-Ghai S,Khan A,Auray-Blais C,West ML,Oudit GY

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:Depression is known to increase the risk of coronary artery disease, but few studies have evaluated the association between depression and peripheral artery disease (PAD). We examined the association of depression with PAD and evaluated potential mediators of this association. METHODS AND RESULTS:We used da...

journal_title：Journal of the American Heart Association

authors： Grenon SM,Hiramoto J,Smolderen KG,Vittinghoff E,Whooley MA,Cohen BE

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Obesity is closely associated with various cardiovascular diseases (CVDs). Adipose tissue inflammation and perturbation of adipokine secretion may contribute to the pathogenesis of CVD. This study aimed to evaluate whether the 2 most abundant adipokines, adipocyte-fatty acid binding protein (A-FABP) and adip...

journal_title：Journal of the American Heart Association

authors： Chow WS,Tso AW,Xu A,Yuen MM,Fong CH,Lam TH,Lo SV,Tse HF,Woo YC,Yeung CY,Cheung BM,Lam KS

更新日期：2013-01-15 00:00:00

abstract：:Background Myocardial infarction (MI) size is a key predictor of prognosis in post-MI patients. Cardiovascular magnetic resonance (CMR) is the gold standard test for MI quantification, but the ECG is less expensive and more widely available. We sought to quantify the relationship between ECG markers and cardiovascular...

journal_title：Journal of the American Heart Association

authors： Lee DC,Albert CM,Narula D,Kadish AH,Panicker GK,Wu E,Schaechter A,Pester J,Chatterjee NA,Cook NR,Goldberger JJ

更新日期：2020-02-04 00:00:00

abstract：BACKGROUND:Metabolic syndrome increases risk for atherosclerotic coronary artery disease, and its prevalence increases with increasing age and body mass index. Adults with congenital heart disease (ACHD) are now living longer and accruing coronary artery disease risk factors. However, the prevalence of metabolic syndro...

journal_title：Journal of the American Heart Association

authors： Deen JF,Krieger EV,Slee AE,Arslan A,Arterburn D,Stout KK,Portman MA

更新日期：2016-02-12 00:00:00

abstract：:[This corrects the article DOI: 10.1161/JAHA.117.005967.]. ...

journal_title：Journal of the American Heart Association

authors：

更新日期：2017-12-23 00:00:00

abstract：BACKGROUND:Conflicting findings of the association between serum uric acid (UA) and stroke have been reported in both men and women, and it is unclear whether this association was different between men and women. We preformed this meta-analysis to assess the sex-specific effect of serum UA on the risk of stroke and its...

journal_title：Journal of the American Heart Association

authors： Zhong C,Zhong X,Xu T,Xu T,Zhang Y

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Right ventricular (RV) diastolic function is impaired in patients with pulmonary arterial hypertension (PAH). Our previous study showed that elevated cardiomyocyte stiffness and myofilament Ca(2+) sensitivity underlie diastolic dysfunction in PAH. This study investigates protein modifications contributing to...

journal_title：Journal of the American Heart Association

authors： Rain S,Bos Dda S,Handoko ML,Westerhof N,Stienen G,Ottenheijm C,Goebel M,Dorfmüller P,Guignabert C,Humbert M,Bogaard HJ,Remedios CD,Saripalli C,Hidalgo CG,Granzier HL,Vonk-Noordegraaf A,van der Velden J,de Man FS

更新日期：2014-06-03 00:00:00

abstract：:Background Both elemental metals and particulate air pollution have been reported to influence adult blood pressure (BP). The aim of this study is to examine which elemental components of particle mass with diameter ≤2.5 μm (PM2.5) are responsible for previously reported associations between PM2.5 and neonatal BP. Met...

journal_title：Journal of the American Heart Association

authors： Zanobetti A,Coull BA,Luttmann-Gibson H,van Rossem L,Rifas-Shiman SL,Kloog I,Schwartz JD,Oken E,Bobb JF,Koutrakis P,Gold DR

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:There is paucity of knowledge concerning the specific age in youth when the associations of metabolic syndrome (MetS) begin to be operative. Thus, we investigated the relation of age to the associations of childhood MetS with adult MetS, type 2 diabetes mellitus and high carotid intima-media thickness. METH...

journal_title：Journal of the American Heart Association

authors： Koskinen J,Magnussen CG,Sinaiko A,Woo J,Urbina E,Jacobs DR Jr,Steinberger J,Prineas R,Sabin MA,Burns T,Berenson G,Bazzano L,Venn A,Viikari JSA,Hutri-Kähönen N,Raitakari O,Dwyer T,Juonala M

更新日期：2017-08-16 00:00:00

abstract：:Background Past reports suggested that total-body irradiation at 0.5 to 1.0 Gy could be responsible for atherosclerosis. Peripheral artery disease ( PAD ) is a manifestation of systematic atherosclerosis. Whether the consequences of a low-to-moderate dose of radiation include increased risk of PAD remains to be determ...

journal_title：Journal of the American Heart Association

authors： Takahashi I,Cologne J,Haruta D,Yamada M,Takahashi T,Misumi M,Fujiwara S,Matsumoto M,Kihara Y,Hida A,Ohishi W

更新日期：2018-12-04 00:00:00

abstract：:Background Coronary flow capacity (CFC), which is a categorical assessment based on the combination of hyperemic coronary flow and coronary flow reserve (CFR), has been introduced as a comprehensive assessment of the coronary circulation to overcome the limitations of CFR alone. The aim of this study was to quantify c...

journal_title：Journal of the American Heart Association

authors： Murai T,Stegehuis VE,van de Hoef TP,Wijntjens GWM,Hoshino M,Kanaji Y,Sugiyama T,Hamaya R,Nijjer SS,de Waard GA,Echavarria-Pinto M,Knaapen P,Meuwissen M,Davies JE,van Royen N,Escaned J,Siebes M,Kirkeeide RL,Gould KL,

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:Epinephrine administered during cardiopulmonary resuscitation (CPR) is associated with severe post-resuscitation myocardial dysfunction. We previously demonstrated that therapeutic hypothermia reduced the severity of post-resuscitation myocardial dysfunction caused by epinephrine; however, the relationship b...

journal_title：Journal of the American Heart Association

authors： Wang W,Hua T,Li H,Wu X,Bradley J,Peberdy MA,Ornato JP,Tang W

更新日期：2018-03-23 00:00:00

abstract：:Background Congenital heart disease is common in patients with Trisomy 13 (T13) and Trisomy 18 (T18), but offering cardiac surgery to these patients has been controversial. We describe the landscape of surgical management across the United States, perioperative risk factors, and surgical outcomes in patients with T13 ...

journal_title：Journal of the American Heart Association

authors： Cooper DS,Riggs KW,Zafar F,Jacobs JP,Hill KD,Pasquali SK,Swanson SK,Gelehrter SK,Wallace A,Jacobs ML,Morales DLS,Bryant R 3rd

更新日期：2019-07-02 00:00:00

abstract：:Background Atherosclerotic vertebrobasilar disease is a significant etiology of posterior circulation stroke. The prospective observational VERiTAS (Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke) study demonstrated that distal hemodynamic status is a robust predictor of subsequent ve...

journal_title：Journal of the American Heart Association

authors： See AP,Pandey DK,Du X,Rose-Finnell L,Charbel FT,Derdeyn CP,Amin-Hanjani S,VERiTAS Study Group* †.

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:Fatty acids constitute the critical components of cell structure and function, and dysregulation of fatty acid composition may exert diverging vascular effects including proliferation, migration, and differentiation of vascular smooth muscle cells (VSMCs). However, direct evidence for this hypothesis has bee...

journal_title：Journal of the American Heart Association

authors： Sunaga H,Matsui H,Anjo S,Syamsunarno MR,Koitabashi N,Iso T,Matsuzaka T,Shimano H,Yokoyama T,Kurabayashi M

更新日期：2016-11-23 00:00:00

abstract：BACKGROUND:Few studies have examined the impact of lifecourse socioeconomic position (SEP) on cardiovascular disease (CVD) risk among African Americans. METHODS AND RESULTS:We used data from the Jackson Heart Study (JHS) to examine the associations of multiple measures of lifecourse SEP with CVD events in a large coho...

journal_title：Journal of the American Heart Association

authors： Gebreab SY,Diez Roux AV,Brenner AB,Hickson DA,Sims M,Subramanyam M,Griswold ME,Wyatt SB,James SA

更新日期：2015-05-27 00:00:00

abstract：:Background Apolipoprotein CIII (apo CIII ) is a crucial player in triglyceride-rich lipoprotein metabolism, but may also act pleiotropically, provoking inflammatory responses and stimulating coagulation. Elevated apo CIII plasma levels have been associated with increased activity of coagulation factors. Since these fe...

journal_title：Journal of the American Heart Association

authors： Olivieri O,Turcato G,Moruzzi S,Castagna A,Girelli D,Pizzolo F,Friso S,Sandri M,Bassi A,Martinelli N

更新日期：2019-01-22 00:00:00

abstract：:Background Exposure to fine airborne particulate matter ( PM 2.5) induces quantitative and qualitative defects in bone marrow-derived endothelial progenitor cells of mice, and similar outcomes in humans may contribute to vascular dysfunction and the cardiovascular morbidity and mortality associated with PM 2.5 exposur...

journal_title：Journal of the American Heart Association

authors： Abplanalp W,Haberzettl P,Bhatnagar A,Conklin DJ,O'Toole TE

更新日期：2019-07-02 00:00:00

abstract：BACKGROUND:Troponin-T elevation is seen commonly in sepsis and septic shock patients admitted to the intensive care unit. We sought to evaluate the role of admission and serial troponin-T testing in the prognostication of these patients. METHODS AND RESULTS:This was a retrospective cohort study from 2007 to 2014 on pa...

journal_title：Journal of the American Heart Association

authors： Vallabhajosyula S,Sakhuja A,Geske JB,Kumar M,Poterucha JT,Kashyap R,Kashani K,Jaffe AS,Jentzer JC

更新日期：2017-09-09 00:00:00