Metabolic Syndrome in Adults With Congenital Heart Disease.

abstract：:Background Meta-analyses are expected to follow a standardized process, and thus, they have become highly formulaic, although there is little evidence that such regimentation yields high-quality results. Methods and Results This article describes the results of a critical examination of 14 published meta-analyses of c...

journal_title：Journal of the American Heart Association

authors： Packer M

更新日期：2019-11-05 00:00:00

abstract：:Background We evaluated a community-engaged stroke preparedness intervention that aimed to increase early hospital arrival and emergency medical services (EMS) utilization among patients with stroke in the South Side of Chicago, Illinois. Methods and Results We compared change in early hospital arrival (<3 hours from ...

journal_title：Journal of the American Heart Association

authors： Prabhakaran S,Richards CT,Kwon S,Wymore E,Song S,Eisenstein A,Brown J,Kandula NR,Mason M,Beckstrom H,Washington KV,Aggarwal NT

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Reactive oxygen species (ROS) are associated with development of coronary artery disease (CAD). However, there's no useful biomarker of ROS in CAD. METHODS AND RESULTS:We recruited 395 consecutive CAD patients who were performed coronary angiography (262 male and 133 female, age 70.2±10), and we measured se...

journal_title：Journal of the American Heart Association

authors： Hirata Y,Yamamoto E,Tokitsu T,Kusaka H,Fujisue K,Kurokawa H,Sugamura K,Maeda H,Tsujita K,Kaikita K,Hokimoto S,Sugiyama S,Ogawa H

更新日期：2015-01-28 00:00:00

abstract：BACKGROUND:Pediatric syncope is common. Cardiac causes are rarely found. We describe and assess a pragmatic approach to these patients first seen by a pediatric cardiologist in the New England region, using Standardized Clinical Assessment and Management Plans (SCAMPs). METHODS AND RESULTS:Ambulatory patients aged 7 t...

journal_title：Journal of the American Heart Association

authors： Paris Y,Toro-Salazar OH,Gauthier NS,Rotondo KM,Arnold L,Hamershock R,Saudek DE,Fulton DR,Renaud A,Alexander ME,New England Congenital Cardiology Association (NECCA).

更新日期：2016-02-19 00:00:00

abstract：:See Article Shah et al. ...

journal_title：Journal of the American Heart Association

authors： Winniford MD

更新日期：2019-06-04 00:00:00

abstract：BACKGROUND:Psychosocial characteristics have a strong effect on risk of depression, and their direct treatment with behavioral interventions reduces rates of depression. Because new-onset poststroke depression (NPSD) is frequent, devastating, and often treatment-resistant, novel preventive efforts are needed. As a firs...

journal_title：Journal of the American Heart Association

authors： Salinas J,Ray RM,Nassir R,Lakshminarayan K,Dording C,Smoller J,Wassertheil-Smoller S,Rosand J,Dunn EC

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Identifying the best markers to judge the adequacy of lipid-lowering treatment is increasingly important for coronary heart disease (CHD) prevention given that several novel, potent lipid-lowering therapies are in development. Reductions in LDL-C, non-HDL-C, or apoB can all be used but which most closely rel...

journal_title：Journal of the American Heart Association

authors： Thanassoulis G,Williams K,Ye K,Brook R,Couture P,Lawler PR,de Graaf J,Furberg CD,Sniderman A

更新日期：2014-04-14 00:00:00

abstract：:Background Characterizing associations of sleep characteristics with blood-glucose-level factors among blacks may clarify the underlying mechanisms of impaired glucose metabolism and help identify treatment targets to prevent diabetes mellitus in blacks. Methods and Results Cross-sectional analyses were conducted in 7...

journal_title：Journal of the American Heart Association

authors： Yano Y,Gao Y,Johnson DA,Carnethon M,Correa A,Mittleman MA,Sims M,Mostofsky E,Wilson JG,Redline S

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Workforce experts predict a future shortage of cardiologists that is expected to impact rural areas more severely than urban areas. However, there is little research on how rural patients are currently served through clinical outreach. This study examines the impact of cardiology outreach in Iowa, a state wi...

journal_title：Journal of the American Heart Association

authors： Gruca TS,Pyo TH,Nelson GC

更新日期：2016-06-30 00:00:00

abstract：BACKGROUND:Cardiovascular clinical trials depend on patient enrollment. Enrollment rates appear inadequate, but little is known about how frequently patients accept or decline offers of enrollment. The objective of this study was to assess trends and predictors of patient acceptance of offers to enroll in clinical tria...

journal_title：Journal of the American Heart Association

authors： Kerkhoff LA,Butler J,Kelkar AA,Shore S,Speight CD,Wall LK,Dickert NW

更新日期：2016-06-17 00:00:00

abstract：BACKGROUND:Heart failure is a highly prevalent cardiovascular complication among patients receiving long-term hemodialysis, but the benefits of carvedilol, bisoprolol, and metoprolol controlled release/extended release on the outcomes of these patients remain unclear. In this study, we address the use of these 3 β-bloc...

journal_title：Journal of the American Heart Association

authors： Tang CH,Wang CC,Chen TH,Hong CY,Sue YM

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Although circumferential pulmonary vein isolation (CPVI) catheter ablation may not be sufficient for long-standing persistent atrial fibrillation (L-PeAF), it is not clear which ablation strategy is beneficial in addition to CPVI. We sought to investigate whether additional complex fractionated atrial electr...

journal_title：Journal of the American Heart Association

authors： Kim TH,Uhm JS,Kim JY,Joung B,Lee MH,Pak HN

更新日期：2017-02-07 00:00:00

abstract：BACKGROUND:Our laboratory has previously demonstrated the importance of a cytoskeletal-based survival signaling pathway using in vitro models of ischemia/reperfusion (IR). However, the importance of this pathway in mediating stress-elicited survival signaling in vivo is unknown. METHODS AND RESULTS:The essential cytos...

journal_title：Journal of the American Heart Association

authors： Perricone AJ,Bivona BJ,Jackson FR,Vander Heide RS

更新日期：2013-09-30 00:00:00

abstract：:BACKGROUND The development of congenital heart disease (CHD) is multifactorial with genetic and environmental influences. We sought to determine the relationship between socioeconomic and environmental factors with the incidence of CHD among live-born infants in California and to determine whether maternal comorbiditi...

journal_title：Journal of the American Heart Association

authors： Peyvandi S,Baer RJ,Chambers CD,Norton ME,Rajagopal S,Ryckman KK,Moon-Grady A,Jelliffe-Pawlowski LL,Steurer MA

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Thoracic endovascular aortic repair is characterized by a substantial need for reintervention. Secondary open aortic procedure becomes necessary when further endoluminal options are exhausted. This synopsis and quantitative analysis of available evidence aims to overcome the limitations of institutional coho...

journal_title：Journal of the American Heart Association

authors： Gambardella I,Antoniou GA,Torella F,Spadaccio C,Oo AY,Gaudino M,Nappi F,Shaw MA,Girardi LN

更新日期：2017-09-13 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate whether the association between baseline cardiovascular health (CVH) and incident cardiovascular disease differs according to coronary heart disease (CHD) and stroke subtypes, and to assess the mediating effect of inflammatory and hemostatic blood biomarkers. METHODS...

journal_title：Journal of the American Heart Association

authors： Gaye B,Tafflet M,Arveiler D,Montaye M,Wagner A,Ruidavets JB,Kee F,Evans A,Amouyel P,Ferrieres J,Empana JP

更新日期：2017-10-17 00:00:00

abstract：:Background Little attention has been paid to the importance of sex in the long-term prognosis of patients undergoing cardiac surgery. Methods and Results We conducted a retrospective cohort study of Ontario residents, aged ≥40 years, who underwent coronary artery bypass grafting (CABG) and/or aortic, mitral, or tricus...

journal_title：Journal of the American Heart Association

authors： Johnston A,Mesana TG,Lee DS,Eddeen AB,Sun LY

更新日期：2019-09-03 00:00:00

abstract：:Background Circulating proteins are exposed to vascular endothelial layer and influence their functions. Among them, adipsin is a member of the trypsin family of peptidases and is mainly secreted from adipocytes, monocytes, and macrophages, catalyzing the rate-limiting step of the alternative complement pathway. Howev...

journal_title：Journal of the American Heart Association

authors： Ohtsuki T,Satoh K,Shimizu T,Ikeda S,Kikuchi N,Satoh T,Kurosawa R,Nogi M,Sunamura S,Yaoita N,Omura J,Aoki T,Tatebe S,Sugimura K,Takahashi J,Miyata S,Shimokawa H

更新日期：2019-12-03 00:00:00

abstract：BACKGROUND:Middle-aged adults with ideal blood pressure, cholesterol, and glucose levels exhibit substantially lower cardiovascular mortality than those with unfavorable levels. Four healthy lifestyle components-optimal body weight, diet, physical activity, and not smoking-are recommended for cardiovascular health (CVH...

journal_title：Journal of the American Heart Association

authors： Gooding HC,Shay CM,Ning H,Gillman MW,Chiuve SE,Reis JP,Allen NB,Lloyd-Jones DM

更新日期：2015-10-29 00:00:00

abstract：BACKGROUND:All clinical and biological manifestations related to postcardiac arrest (CA) syndrome are attributed to ischemia-reperfusion injury in various organs including brain and heart. Molecular hydrogen (H(2)) has potential as a novel antioxidant. This study tested the hypothesis that inhalation of H(2) gas starti...

journal_title：Journal of the American Heart Association

authors： Hayashida K,Sano M,Kamimura N,Yokota T,Suzuki M,Maekawa Y,Kawamura A,Abe T,Ohta S,Fukuda K,Hori S

更新日期：2012-10-01 00:00:00

abstract：:Background There are no risk scores designed specifically for mortality risk prediction in unselected cardiac intensive care unit (CICU) patients. We sought to develop a novel CICU-specific risk score for prediction of hospital mortality using variables available at the time of CICU admission. Methods and Results A da...

journal_title：Journal of the American Heart Association

authors： Jentzer JC,Anavekar NS,Bennett C,Murphree DH,Keegan MT,Wiley B,Morrow DA,Murphy JG,Bell MR,Barsness GW

更新日期：2019-09-03 00:00:00

abstract：:Background Low income and short education have been found to be independently associated with inferior survival after coronary artery bypass grafting (CABG), whereas the use of secondary prevention medications is associated with improved survival. We investigated whether underusage of secondary prevention medications ...

journal_title：Journal of the American Heart Association

authors： Nielsen SJ,Karlsson M,Björklund E,Martinsson A,Hansson EC,Malm CJ,Pivodic A,Jeppsson A

更新日期：2020-03-03 00:00:00

abstract：:Background Coronary flow capacity (CFC), which is a categorical assessment based on the combination of hyperemic coronary flow and coronary flow reserve (CFR), has been introduced as a comprehensive assessment of the coronary circulation to overcome the limitations of CFR alone. The aim of this study was to quantify c...

journal_title：Journal of the American Heart Association

authors： Murai T,Stegehuis VE,van de Hoef TP,Wijntjens GWM,Hoshino M,Kanaji Y,Sugiyama T,Hamaya R,Nijjer SS,de Waard GA,Echavarria-Pinto M,Knaapen P,Meuwissen M,Davies JE,van Royen N,Escaned J,Siebes M,Kirkeeide RL,Gould KL,

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:Statin therapy reduces the risk of cardiovascular events in patients with obstructive coronary artery disease. The aim of the present study was to determine the effects of statins on the prognosis of patients with coronary vasospastic angina (VSA) free of significant atherosclerotic stenosis. METHODS AND RE...

journal_title：Journal of the American Heart Association

authors： Ishii M,Kaikita K,Sato K,Yamanaga K,Miyazaki T,Akasaka T,Tabata N,Arima Y,Sueta D,Sakamoto K,Yamamoto E,Tsujita K,Yamamuro M,Kojima S,Soejima H,Hokimoto S,Matsui K,Ogawa H

更新日期：2016-05-20 00:00:00

abstract：BACKGROUND:Perioperative antiplatelet agents potentially increase bleeding after non-ST-segment elevation (NSTE) acute coronary syndromes (ACS). The protease-activated receptor 1 antagonist vorapaxar reduced cardiovascular events and was associated with increased bleeding versus placebo in NSTE ACS, but its efficacy an...

journal_title：Journal of the American Heart Association

authors： van Diepen S,Tricoci P,Podder M,Westerhout CM,Aylward PE,Held C,Van de Werf F,Strony J,Wallentin L,Moliterno DJ,White HD,Mahaffey KW,Harrington RA,Armstrong PW

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:A higher milk consumption may be associated with a lower stroke risk. We conducted a comprehensive systematic review and dose-response meta-analysis of milk and other dairy products in relation to stroke risk. METHODS AND RESULTS:Through a systematic literature search, prospective cohort studies of dairy fo...

journal_title：Journal of the American Heart Association

authors： de Goede J,Soedamah-Muthu SS,Pan A,Gijsbers L,Geleijnse JM

更新日期：2016-05-20 00:00:00

abstract：:Background The blood-brain barrier (BBB) is critical for cerebrovascular health. Although aging impairs the integrity of the BBB, the mechanisms behind this phenomenon are not clear. As mitochondrial components activate inflammation as mitochondria become dysfunctional, we examined how aging impacts cerebrovascular mi...

journal_title：Journal of the American Heart Association

authors： Tyrrell DJ,Blin MG,Song J,Wood SC,Goldstein DR

更新日期：2020-12-01 00:00:00

abstract：:Background To assess differences in platelet inhibition during ticagrelor monotherapy (TIC) or dual therapy with ticagrelor and aspirin (TIC+ASP) in patients after percutaneous coronary intervention using a comprehensive panel of functional tests. Methods and Results In a single-center parallel group, open label, rand...

journal_title：Journal of the American Heart Association

authors： Johnson TW,Baos S,Collett L,Hutchinson JL,Nkau M,Molina M,Aungraheeta R,Reilly-Stitt C,Bowles R,Reeves BC,Rogers CA,Mundell SJ,Baumbach A,Mumford AD

更新日期：2020-12-15 00:00:00

abstract：:Background Acute type A aortic dissection presents with abrupt onset of pain that requires emergency surgery. However, minimal research exists on posttraumatic stress disorder (PTSD) in survivors. We aimed to quantify the prevalence and describe characteristics of PTSD in patients following dissection. Methods and Res...

journal_title：Journal of the American Heart Association

authors： Pasadyn SR,Roselli EE,Artis AS,Pasadyn CL,Phelan D,Hurley K,Desai MY,Blackstone EH

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:Vascular smooth muscle cell proliferation, migration, and dedifferentiation are critical for vascular diseases. Recently, it was demonstrated that Notch receptors have opposing effects on intima formation after vessel injury. Therefore, it is important to investigate the specific regulatory pathways that act...

journal_title：Journal of the American Heart Association

authors： Jiang D,Zhuang J,Peng W,Lu Y,Liu H,Zhao Q,Chi C,Li X,Zhu G,Xu X,Yan C,Xu Y,Ge J,Pang J

更新日期：2017-07-11 00:00:00