Association Between Prevalence of Peripheral Artery Disease and Radiation Exposure in the Atomic Bomb Survivors.

abstract：:Background Cardiac hypertrophy has been recognized as an important independent risk factor for the development of heart failure and increases the risk of cardiac morbidity and mortality. A disintegrin and metalloprotease 23 (ADAM23), a member of ADAM family, is involved in cancer and neuronal differentiation. Although...

journal_title：Journal of the American Heart Association

authors： Xiang M,Luo H,Wu J,Ren L,Ding X,Wu C,Chen J,Chen S,Zhang H,Yu L,Zou Y,Xu H,Ye P,Chen M,Xia J

更新日期：2018-09-18 00:00:00

abstract：BACKGROUND:Natriuretic peptides promote natriuresis, diuresis, and vasodilation. Experimental deficiency of natriuretic peptides leads to hypertension (HTN) and cardiac hypertrophy, conditions more common among African Americans. Hospital-based studies suggest that African Americans may have reduced circulating natriur...

journal_title：Journal of the American Heart Association

authors： Gupta DK,Claggett B,Wells Q,Cheng S,Li M,Maruthur N,Selvin E,Coresh J,Konety S,Butler KR,Mosley T,Boerwinkle E,Hoogeveen R,Ballantyne CM,Solomon SD

更新日期：2015-05-21 00:00:00

abstract：BACKGROUND:Participation in cardiac rehabilitation (CR) is an essential component of care for patients with coronary artery disease. However, little is known about its benefit on cardiovascular outcomes in patients with diabetes mellitus (DM) who have undergone percutaneous coronary intervention. The aim of our study w...

journal_title：Journal of the American Heart Association

authors： Jiménez-Navarro MF,Lopez-Jimenez F,Pérez-Belmonte LM,Lennon RJ,Diaz-Melean C,Rodriguez-Escudero JP,Goel K,Crusan D,Prasad A,Squires RW,Thomas RJ

更新日期：2017-10-11 00:00:00

abstract：BACKGROUND:Single-electrode ablation of the main renal artery for renal sympathetic denervation showed mixed blood pressure (BP)-lowering effects. Further improvement of the technique seems crucial to optimize effectiveness of the procedure. Because sympathetic nerve fibers are closer to the lumen in the distal part of...

journal_title：Journal of the American Heart Association

authors： Fengler K,Ewen S,Höllriegel R,Rommel KP,Kulenthiran S,Lauder L,Cremers B,Schuler G,Linke A,Böhm M,Mahfoud F,Lurz P

更新日期：2017-08-10 00:00:00

abstract：BACKGROUND:Sleep disordered breathing in children is associated with increased blood flow velocity and sympathetic overactivity. Sympathetic overactivity results in peripheral vasoconstriction and reduced systemic vascular compliance, which increases blood flow velocity during systole. Augmented blood flow velocity is ...

journal_title：Journal of the American Heart Association

authors： Kontos A,Lushington K,Martin J,Schwarz Q,Green R,Wabnitz D,Xu X,M Sokoya E,Willoughby S,Baumert M,Ferrante A,La Forgia M,Kennedy D

更新日期：2017-07-17 00:00:00

abstract：:Background Improving health-related quality of life is an important goal in the management of patients with heart failure (HF). Defining health-related quality of life changes over time in patients with HF with preserved (HFpEF) or reduced ejection fraction and showing their association with other important clinical e...

journal_title：Journal of the American Heart Association

authors： Sepehrvand N,Savu A,Spertus JA,Dyck JRB,Anderson T,Howlett J,Paterson I,Oudit GY,Kaul P,McAlister FA,Ezekowitz JA,Alberta HEART Investigators*.

更新日期：2020-09-01 00:00:00

abstract：:Background Recent studies suggest that mavacamten (Myk461), a small myosin-binding molecule, decreases hypercontractility in myocardium expressing hypertrophic cardiomyopathy-causing missense mutations in myosin heavy chain. However, the predominant feature of most mutations in cardiac myosin binding protein-C ( cMyBP...

journal_title：Journal of the American Heart Association

authors： Mamidi R,Li J,Doh CY,Verma S,Stelzer JE

更新日期：2018-09-04 00:00:00

abstract：:The primary goal of the initial ECG evaluation of every wide complex tachycardia is to determine whether the tachyarrhythmia has a ventricular or supraventricular origin. The answer to this question drives immediate patient care decisions, ensuing clinical workup, and long-term management strategies. Thus, the importa...

journal_title：Journal of the American Heart Association

authors： Kashou AH,Noseworthy PA,DeSimone CV,Deshmukh AJ,Asirvatham SJ,May AM

更新日期：2020-06-02 00:00:00

abstract：BACKGROUND:We studied (1) the rates of stroke or systemic embolism and bleeding in patients with atrial fibrillation and peripheral artery disease (PAD) and (2) the efficacy and safety of apixaban versus warfarin in patients with atrial fibrillation with and without PAD. METHODS AND RESULTS:The Apixaban for Reduction ...

journal_title：Journal of the American Heart Association

authors： Hu PT,Lopes RD,Stevens SR,Wallentin L,Thomas L,Alexander JH,Hanna M,Lewis BS,Verheugt FW,Granger CB,Jones WS

更新日期：2017-01-17 00:00:00

abstract：BACKGROUND:We previously identified peritoneal B1a cells that secrete natural IgM as a key atheroprotective B cell subset. However, the molecules that activate atheroprotective B1a cells are unknown. Here, we investigated whether Toll-like receptors (TLRs) TLR2, TLR4, and TLR9 expressed by B1a cells are required for Ig...

journal_title：Journal of the American Heart Association

authors： Hosseini H,Li Y,Kanellakis P,Tay C,Cao A,Liu E,Peter K,Tipping P,Toh BH,Bobik A,Kyaw T

更新日期：2016-11-14 00:00:00

abstract：BACKGROUND:Intravascular imaging can facilitate chronic total occlusion (CTO) percutaneous coronary intervention. METHODS AND RESULTS:We examined the frequency of use and outcomes of intravascular imaging among 619 CTO percutaneous coronary interventions performed between 2012 and 2015 at 7 US centers. Mean age was 65...

journal_title：Journal of the American Heart Association

authors： Karacsonyi J,Alaswad K,Jaffer FA,Yeh RW,Patel M,Bahadorani J,Karatasakis A,Danek BA,Doing A,Grantham JA,Karmpaliotis D,Moses JW,Kirtane A,Parikh M,Ali Z,Lombardi WL,Kandzari DE,Lembo N,Garcia S,Wyman MR,Alame A,

更新日期：2016-08-20 00:00:00

abstract：:Background Recent studies have raised concerns about the reduced efficacy of citalopram when used concurrently with proton pump inhibitors. The aim of this study was to evaluate the associations between clinical use of citalopram and omeprazole and the risk of sudden cardiac arrest (SCA) in an Asian population. Method...

journal_title：Journal of the American Heart Association

authors： Wu WT,Tsai CT,Chou YC,Ku PM,Chen YC,You SL,Hung CF,Sun CA

更新日期：2019-10-15 00:00:00

abstract：:See Article Ramkumar et al. ...

journal_title：Journal of the American Heart Association

authors： Braun JD,Kougias P

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Cardiovascular clinical trials depend on patient enrollment. Enrollment rates appear inadequate, but little is known about how frequently patients accept or decline offers of enrollment. The objective of this study was to assess trends and predictors of patient acceptance of offers to enroll in clinical tria...

journal_title：Journal of the American Heart Association

authors： Kerkhoff LA,Butler J,Kelkar AA,Shore S,Speight CD,Wall LK,Dickert NW

更新日期：2016-06-17 00:00:00

abstract：BACKGROUND:Our previous randomized controlled trial demonstrated cardiorespiratory protection by remote ischemic preconditioning (RIPC) in children before cardiac surgery. However, the impact of RIPC on myocardial prosurvival intracellular signaling remains unknown in cyanosis. RIPC may augment phosphorylated protein s...

journal_title：Journal of the American Heart Association

authors： Pepe S,Liaw NY,Hepponstall M,Sheeran FL,Yong MS,d'Udekem Y,Cheung MM,Konstantinov IE

更新日期：2013-05-10 00:00:00

abstract：:Background Chronic kidney disease is a recognized independent risk factor for cardiovascular disease, but whether the risks of ST-segment-elevation myocardial infarction ( STEMI ) and non-ST-segment-elevation myocardial infarction ( NSTEMI ) differ in the chronic kidney disease population is unknown. Methods and Resul...

journal_title：Journal of the American Heart Association

authors： de Chickera SN,Bota SE,Kuwornu JP,Wijeysundera HC,Molnar AO,Lam NN,Silver SA,Clark EG,Sood MM

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:Cardiac mesenchymal cell (CMC) administration improves cardiac function in animal models of heart failure. Although the precise mechanisms remain unclear, transdifferentiation and paracrine signaling are suggested to underlie their cardiac reparative effects. We have shown that histone deacetylase 1 (HDAC1) ...

journal_title：Journal of the American Heart Association

authors： Moore JB 4th,Zhao J,Fischer AG,Keith MCL,Hagan D,Wysoczynski M,Bolli R

更新日期：2017-07-05 00:00:00

abstract：:Background Cardiology has advanced guideline development and quality measurement. Recognizing the substantial benefits of guideline-directed medical therapy, this study aims to measure and explain apparent deviations in heart failure ( HF ) guideline adherence by clinicians at hospital discharge and describe any impac...

journal_title：Journal of the American Heart Association

authors： Gilstrap LG,Stevenson LW,Small R,Parambi R,Hamershock R,Greenberg J,Carr C,Ghazinouri R,Rathman L,Han E,Mehra MR,Desai AS

更新日期：2018-08-07 00:00:00

abstract：BACKGROUND:Sex-based differences in clinical presentation, pathophysiology, and outcomes of patients with acute chest pain are increasingly being recognized, but are not implemented in guidelines and clinical prediction tools. We evaluated the performance of the HEART score in women versus men, because sex-based differ...

journal_title：Journal of the American Heart Association

authors： Bank IEM,de Hoog VC,de Kleijn DPV,Pasterkamp G,Doevendans PA,den Ruijter HM,Dalmeijer G,Wildbergh TX,Mosterd A,Timmers L

更新日期：2017-06-21 00:00:00

abstract：BACKGROUND:The structure of the aorta is considered to influence exercise systolic blood pressure (SBP) response, which, in turn, might impact upon adverse outcomes. The current study sought to investigate the relationship of aortic calcification and exercise SBP with adverse outcomes among elderly individuals. METHOD...

journal_title：Journal of the American Heart Association

authors： Cho IJ,Chang HJ,Cho I,Heo R,Lee SE,Shim CY,Hong GR,Chung N

更新日期：2016-04-22 00:00:00

abstract：:Background Acute type A aortic dissection presents with abrupt onset of pain that requires emergency surgery. However, minimal research exists on posttraumatic stress disorder (PTSD) in survivors. We aimed to quantify the prevalence and describe characteristics of PTSD in patients following dissection. Methods and Res...

journal_title：Journal of the American Heart Association

authors： Pasadyn SR,Roselli EE,Artis AS,Pasadyn CL,Phelan D,Hurley K,Desai MY,Blackstone EH

更新日期：2020-05-05 00:00:00

abstract：:Background Patients presenting to hospitals during non-weekday hours experience worse outcomes, often attributed to reduced staffing. The American Heart Association International Stroke Conference ( ISC ) is well attended by stroke clinicians. We sought to determine whether patients with acute ischemic stroke ( AIS ) ...

journal_title：Journal of the American Heart Association

authors： Messé SR,Mullen MT,Cox M,Fonarow GC,Smith EE,Saver JL,Reeves MJ,Bhatt DL,Matsouaka R,Schwamm LH

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:Diabetes is associated with coronary arteriolar endothelial dysfunction. We investigated the role of the small/intermediate (SK(Ca)/IK(Ca)) conductance of calcium-activated potassium channels in diabetes-related endothelial dysfunction. METHODS AND RESULTS:Coronary arterioles (80 to 150 μm in diameter) were...

journal_title：Journal of the American Heart Association

authors： Liu Y,Xie A,Singh AK,Ehsan A,Choudhary G,Dudley S,Sellke FW,Feng J

更新日期：2015-08-24 00:00:00

abstract：:Background Global fractional flow reserve (FFR) (ie, the sum of the FFR values in the 3 major coronary arteries) is a physiologic correlate of global atherosclerotic burden. The objective of the present study was to investigate the value of global FFR in predicting long-term clinical outcome of patients with stable co...

journal_title：Journal of the American Heart Association

authors： Fournier S,Collet C,Xaplanteris P,Zimmermann FM,Toth GG,Tonino PAL,Pijls NHJ,Colaiori I,Di Gioia G,Barbato E,Jüni P,Fearon WF,De Bruyne B

更新日期：2020-12-15 00:00:00

abstract：:Background Genetic testing in pediatric primary dilated cardiomyopathy (DCM) patients has identified numerous disease-causing variants, but few studies have evaluated genetic testing outcomes in this population in the context of patient and familial clinical data or assessed the clinical implications of temporal chang...

journal_title：Journal of the American Heart Association

authors： Quiat D,Witkowski L,Zouk H,Daly KP,Roberts AE

更新日期：2020-06-02 00:00:00

abstract：:Background Mobile health (mHealth) technologies can deliver interventions to prevent and manage cardiovascular disease (CVD), but mHealth uptake among those with or at risk for CVD remains incompletely explored. Therefore, in this group, we assessed the prevalence of mHealth access and usage, and the association betwe...

journal_title：Journal of the American Heart Association

authors： Shan R,Ding J,Plante TB,Martin SS

更新日期：2019-12-17 00:00:00

abstract：:Background Cardiovascular disease is the leading cause of morbidity and mortality in patients with end-stage renal disease. Heart rhythm complexity analysis has been shown to be useful in predicting outcomes in various diseases; however, data on patients with end-stage renal disease are limited. In this study, we anal...

journal_title：Journal of the American Heart Association

authors： Tsai CH,Huang JW,Lin C,Ma HP,Lo MT,Liu LD,Lin LY,Lin CT,Hung CS,Peng CK,Lin YH

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:The 2013 American College of Cardiology/American Heart Association cholesterol guidelines recommend high-intensity statins for patients after myocardial infarction (MI) rather than treating to a low-density lipoprotein cholesterol goal, as the previous ATP III (Adult Treatment Panel third report) guidelines ...

journal_title：Journal of the American Heart Association

authors： Wang WT,Hellkamp A,Doll JA,Thomas L,Navar AM,Fonarow GC,Julien HM,Peterson ED,Wang TY

更新日期：2018-01-25 00:00:00

abstract：:Background Atrial fibrillation (AF) is associated with cognitive decline. Whether left atrial enlargement (LAE), a critical substrate for AF, is also associated is less well established. Therefore, we assessed the association of LAE and AF with cognitive decline in the ARIC-NCS (Atherosclerosis Risk in Communities Neu...

journal_title：Journal of the American Heart Association

authors： Zhang MJ,Norby FL,Lutsey PL,Mosley TH,Cogswell RJ,Konety SH,Chao TF,Shah AM,Solomon SD,Alonso A,Chen LY

更新日期：2019-12-03 00:00:00

abstract：:Background Muscular dystrophy (MD) causes a progressive cardiomyopathy characterized by diffuse fibrosis, arrhythmia, heart failure, and early death. Activation of the thromboxane-prostanoid receptor (TPr) increases calcium transients in cardiomyocytes and is proarrhythmic and profibrotic. We hypothesized that TPr act...

journal_title：Journal of the American Heart Association

authors： West JD,Galindo CL,Kim K,Shin JJ,Atkinson JB,Macias-Perez I,Pavliv L,Knollmann BC,Soslow JH,Markham LW,Carrier EJ

更新日期：2019-11-05 00:00:00