Cardiovascular Outcomes Associated With Clinical Use of Citalopram and Omeprazole: A Nationwide Population-Based Cohort Study.

abstract：BACKGROUND:Sex-based differences in clinical presentation, pathophysiology, and outcomes of patients with acute chest pain are increasingly being recognized, but are not implemented in guidelines and clinical prediction tools. We evaluated the performance of the HEART score in women versus men, because sex-based differ...

journal_title：Journal of the American Heart Association

authors： Bank IEM,de Hoog VC,de Kleijn DPV,Pasterkamp G,Doevendans PA,den Ruijter HM,Dalmeijer G,Wildbergh TX,Mosterd A,Timmers L

更新日期：2017-06-21 00:00:00

abstract：:Background The management of the cardiorenal syndrome in advanced heart failure is challenging, and the role of inotropic drugs has not been fully defined. Our aim was to compare the renal effects of levosimendan versus dobutamine in patients with heart failure and renal impairment. Methods and Results In a randomized...

journal_title：Journal of the American Heart Association

authors： Lannemyr L,Ricksten SE,Rundqvist B,Andersson B,Bartfay SE,Ljungman C,Dahlberg P,Bergh N,Hjalmarsson C,Gilljam T,Bollano E,Karason K

更新日期：2018-08-21 00:00:00

abstract：:Background Some, but not all, studies report associations between shift work and hypertension, suggesting that particular subgroups may be at risk. We examined moderating effects of sleep duration and circadian preference on the relationship between shift work and new blood pressure (BP) medicine use at follow-up. Met...

journal_title：Journal of the American Heart Association

authors： Riegel B,Daus M,Lozano AJ,Malone SK,Patterson F,Hanlon AL

更新日期：2019-10-15 00:00:00

abstract：:Background Angiotensin II type 1 receptor ( AT 1R) autoantibody ( AT 1- AA ) was first identified as a causative factor in preeclampsia. Unlike physiological ligand angiotensin II (Ang II ), AT 1- AA can induce vasoconstriction in a sustained manner, causing a series of adverse effects, such as vascular injury and poo...

journal_title：Journal of the American Heart Association

authors： Bian J,Lei J,Yin X,Wang P,Wu Y,Yang X,Wang L,Zhang S,Liu H,Fu MLX

更新日期：2019-03-19 00:00:00

abstract：BACKGROUND:There is increasing evidence implicating atrial mitochondrial dysfunction in the pathogenesis of atrial fibrillation. In this study, we explored whether alogliptin, a dipeptidyl peptidase-4 inhibitor, can prevent mitochondrial dysfunction and atrial remodeling in a diabetic rabbit model. METHODS AND RESULTS...

journal_title：Journal of the American Heart Association

authors： Zhang X,Zhang Z,Zhao Y,Jiang N,Qiu J,Yang Y,Li J,Liang X,Wang X,Tse G,Li G,Liu T

更新日期：2017-05-15 00:00:00

abstract：:Background Short-term variability of the QT interval (STVQT) has been proposed as a novel electrophysiological marker for the prediction of imminent ventricular arrhythmias in animal models. Our aim is to study whether STVQT can predict imminent ventricular arrhythmias in patients. Methods and Results In 2331 patients...

journal_title：Journal of the American Heart Association

authors： Smoczyńska A,Loen V,Sprenkeler DJ,Tuinenburg AE,Ritsema van Eck HJ,Malik M,Schmidt G,Meine M,Vos MA

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Bromocriptine-QR (a quick-release formulation of bromocriptine mesylate), a dopamine D2 receptor agonist, is a US Food and Drug Administrration-approved treatment for type 2 diabetes mellitus (T2DM). A 3070-subject randomized trial demonstrated a significant, 40% reduction in relative risk among bromocriptin...

journal_title：Journal of the American Heart Association

authors： Gaziano JM,Cincotta AH,Vinik A,Blonde L,Bohannon N,Scranton R

更新日期：2012-10-01 00:00:00

abstract：:Background The regulation of sodium excretion is important in the pathogenesis of hypertension and salt sensitivity is predictive of cardiovascular events and mortality. C57Bl/6 and BALB/c mice have different blood pressure sensitivities to salt intake. High salt intake increases blood pressure in some C57Bl/6J mouse ...

journal_title：Journal of the American Heart Association

authors： Cuevas S,Asico LD,Jose PA,Konkalmatt P

更新日期：2020-01-07 00:00:00

abstract：BACKGROUND:The MMP (matrix metalloproteinase) family plays diverse and critical roles in directing vascular wall remodeling in atherosclerosis. Unlike secreted-type MMPs, a member of the membrane-type MMP family, MT1-MMP (membrane-type 1 MMP; MMP14), mediates pericellular extracellular matrix degradation that is indisp...

journal_title：Journal of the American Heart Association

authors： Barnes RH 2nd,Akama T,Öhman MK,Woo MS,Bahr J,Weiss SJ,Eitzman DT,Chun TH

更新日期：2017-07-22 00:00:00

abstract：BACKGROUND:Adults with repaired coarctation of the aorta (CoA) have reduced long-term survival compared with the general population. This study aimed to determine whether CoA is independently associated with premature ischemic and hemorrhagic stroke in the contemporary era. METHODS AND RESULTS:This was a cross-section...

journal_title：Journal of the American Heart Association

authors： Pickard SS,Gauvreau K,Gurvitz M,Gagne JJ,Opotowsky AR,Jenkins KJ,Prakash A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:All clinical and biological manifestations related to postcardiac arrest (CA) syndrome are attributed to ischemia-reperfusion injury in various organs including brain and heart. Molecular hydrogen (H(2)) has potential as a novel antioxidant. This study tested the hypothesis that inhalation of H(2) gas starti...

journal_title：Journal of the American Heart Association

authors： Hayashida K,Sano M,Kamimura N,Yokota T,Suzuki M,Maekawa Y,Kawamura A,Abe T,Ohta S,Fukuda K,Hori S

更新日期：2012-10-01 00:00:00

abstract：:Background Meta-analyses are expected to follow a standardized process, and thus, they have become highly formulaic, although there is little evidence that such regimentation yields high-quality results. Methods and Results This article describes the results of a critical examination of 14 published meta-analyses of c...

journal_title：Journal of the American Heart Association

authors： Packer M

更新日期：2019-11-05 00:00:00

abstract：:Background Endovascular repair has become a viable alternative for aortic pathological features, including those located within the aortic arch. We investigated the anatomic suitability for branched thoracic endovascular repair in patients previously treated with conventional open surgery for aortic arch pathological ...

journal_title：Journal of the American Heart Association

authors： Smorenburg SPM,Montesano M,Hoogteijling TJ,Truijers M,Symersky P,Jansen EK,Zandbergen HR,Wisselink W,van Schaik TG,Yeung KK

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Mitochondrial aldehyde dehydrogenase 2 (ALDH2) plays a key role in removing toxic aldehydes. Deficient variant ALDH2*2 genotype is prevalent in up to 40% of the East Asians and reported to be associated with acute myocardial infarction (AMI). To elucidate the mechanisms underlying the association of ALDH2*2 ...

journal_title：Journal of the American Heart Association

authors： Mizuno Y,Hokimoto S,Harada E,Kinoshita K,Nakagawa K,Yoshimura M,Ogawa H,Yasue H

更新日期：2016-05-06 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether reducing plasma homocysteine concentrations with long-term, combined treatment with folic acid, vitamin B6, and vitamin B12 alters plasma biomarkers of inflammation and endothelial dysfunction in women at increased risk of cardiovascular disease. METHODS AND RE...

journal_title：Journal of the American Heart Association

authors： Christen WG,Cook NR,Van Denburgh M,Zaharris E,Albert CM,Manson JE

更新日期：2018-05-18 00:00:00

abstract：BACKGROUND:Transcatheter pulmonary valve implantation is approved for the treatment of dysfunctional right ventricle to pulmonary artery conduits. However, the literature is limited because of a small patient population, and it does not reflect changing procedural practice patterns over the last decade. METHODS AND RE...

journal_title：Journal of the American Heart Association

authors： Chatterjee A,Bajaj NS,McMahon WS,Cribbs MG,White JS,Mukherjee A,Law MA

更新日期：2017-08-04 00:00:00

abstract：BACKGROUND:Short-term exposures to fine (<2.5 μm aerodynamic diameter) ambient particulate-matter (PM) have been related with increased blood pressure (BP) in controlled-human exposure and community-based studies. However, whether coarse (2.5 to 10 μm) PM exposure increases BP is uncertain. Recent observational studies...

journal_title：Journal of the American Heart Association

authors： Bellavia A,Urch B,Speck M,Brook RD,Scott JA,Albetti B,Behbod B,North M,Valeri L,Bertazzi PA,Silverman F,Gold D,Baccarelli AA

更新日期：2013-06-19 00:00:00

abstract：:Background Left ventricular assist devices (LVADs) generate electromagnetic interference that causes high-frequency noise artifacts on 12-lead ECGs. We describe the causes of this interference and potential solutions to aid ECG interpretation in patients with LVAD. Methods and Results Waveform data from ECGs performed...

journal_title：Journal of the American Heart Association

authors： Loring Z,Sen S,Black-Maier E,Atwater BD,Russell SD,DeVore AD,Piccini JP

更新日期：2020-08-18 00:00:00

abstract：BACKGROUND:Periaortic fat, because of its contiguity with the aorta, may promote vascular remodeling and aortic dilatation. However, the relations between perioartic fat depots and aortic dimensions have not been previously described. METHODS AND RESULTS:A total of 3001 individuals (mean age 50 ± 10 years, 49% women) ...

journal_title：Journal of the American Heart Association

authors： Thanassoulis G,Massaro JM,Corsini E,Rogers I,Schlett CL,Meigs JB,Hoffmann U,O'Donnell CJ,Fox CS

更新日期：2012-12-01 00:00:00

abstract：:Background Dietary micronutrient deficiencies have been shown to predict event-free survival in other countries but have not been examined in patients with heart failure living in the United States. The purpose of this study was to determine whether number of dietary micronutrient deficiencies in patients with heart f...

journal_title：Journal of the American Heart Association

authors： Lennie TA,Andreae C,Rayens MK,Song EK,Dunbar SB,Pressler SJ,Heo S,Kim J,Moser DK

更新日期：2018-09-04 00:00:00

abstract：:Background Limited data are available on the prospective relationship between beverage consumption and plasma lipid and lipoprotein concentrations. Two major sources of sugar in the US diet are sugar-sweetened beverages (SSBs) and 100% fruit juices. Low-calorie sweetened beverages are common replacements. Methods and ...

journal_title：Journal of the American Heart Association

authors： Haslam DE,Peloso GM,Herman MA,Dupuis J,Lichtenstein AH,Smith CE,McKeown NM

更新日期：2020-03-03 00:00:00

abstract：:Despite numerous advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains a leading cause of morbidity and mortality. Novel and inexpensive interventions that can contribute to the primary and secondary prevention of cardiovascular disease are of interest. Numerous studies have repor...

journal_title：Journal of the American Heart Association

authors： Levine GN,Lange RA,Bairey-Merz CN,Davidson RJ,Jamerson K,Mehta PK,Michos ED,Norris K,Ray IB,Saban KL,Shah T,Stein R,Smith SC Jr,American Heart Association Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nur

更新日期：2017-09-28 00:00:00

abstract：BACKGROUND:The liver X receptors (LXRs; α/β) are nuclear receptors known to regulate cholesterol homeostasis and the production of select hematopoietic populations. The objective of this study was to determine the importance of LXRs and a high-fat high-cholesterol diet on global hematopoiesis, with special emphasis on ...

journal_title：Journal of the American Heart Association

authors： Rasheed A,Tsai R,Cummins CL

更新日期：2018-05-08 00:00:00

abstract：:Background Type 2 diabetes mellitus (T2 DM ) is considered a cardiovascular disease ( CVD ) risk equivalent, thereby linking assessment of cardiometabolic risk with that of CVD risk over time. Our goal was to determine how commonly used CVD risk scores and metabolic syndrome (MetS) severity performed in predicting T2 ...

journal_title：Journal of the American Heart Association

authors： Gurka MJ,Filipp SL,Pearson TA,DeBoer MD

更新日期：2018-08-21 00:00:00

abstract：:The primary goal of the initial ECG evaluation of every wide complex tachycardia is to determine whether the tachyarrhythmia has a ventricular or supraventricular origin. The answer to this question drives immediate patient care decisions, ensuing clinical workup, and long-term management strategies. Thus, the importa...

journal_title：Journal of the American Heart Association

authors： Kashou AH,Noseworthy PA,DeSimone CV,Deshmukh AJ,Asirvatham SJ,May AM

更新日期：2020-06-02 00:00:00

abstract：BACKGROUND:Sleep disordered breathing in children is associated with increased blood flow velocity and sympathetic overactivity. Sympathetic overactivity results in peripheral vasoconstriction and reduced systemic vascular compliance, which increases blood flow velocity during systole. Augmented blood flow velocity is ...

journal_title：Journal of the American Heart Association

authors： Kontos A,Lushington K,Martin J,Schwarz Q,Green R,Wabnitz D,Xu X,M Sokoya E,Willoughby S,Baumert M,Ferrante A,La Forgia M,Kennedy D

更新日期：2017-07-17 00:00:00

abstract：:Background Unruptured intracerebral aneurysm wall enhancement (AWE) on vessel wall magnetic resonance imaging scans may be a promising predictor for rupture-prone intracerebral aneurysms. However, the pathophysiology of AWE remains unclear. To this end, the association between AWE and histopathological changes was ass...

journal_title：Journal of the American Heart Association

authors： Zhong W,Su W,Li T,Tan X,Chen C,Wang Q,Wang D,Su W,Wang Y

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND:Besides hypertension, obesity and the metabolic syndrome have recently emerged as risk factors for atrial fibrillation. This study sought to delineate the development of an arrhythmogenic substrate for atrial fibrillation in hypertension with and without concomitant obesity and metabolic syndrome. METHODS A...

journal_title：Journal of the American Heart Association

authors： Hohl M,Lau DH,Müller A,Elliott AD,Linz B,Mahajan R,Hendriks JML,Böhm M,Schotten U,Sanders P,Linz D

更新日期：2017-09-17 00:00:00

abstract：BACKGROUND:Treatment decisions for aortic valve replacement (AVR) should be sensitive to patient preferences. However, we lack knowledge of patient preferences and how to obtain them. METHODS AND RESULTS:We assessed the mortality risk patients were willing to accept when undergoing AVR by using the Standard Gamble met...

journal_title：Journal of the American Heart Association

authors： Hussain AI,Garratt AM,Brunborg C,Aakhus S,Gullestad L,Pettersen KI

更新日期：2016-03-18 00:00:00

abstract：:Background Atrial fibrillation (AF) is associated with cognitive decline. Whether left atrial enlargement (LAE), a critical substrate for AF, is also associated is less well established. Therefore, we assessed the association of LAE and AF with cognitive decline in the ARIC-NCS (Atherosclerosis Risk in Communities Neu...

journal_title：Journal of the American Heart Association

authors： Zhang MJ,Norby FL,Lutsey PL,Mosley TH,Cogswell RJ,Konety SH,Chao TF,Shah AM,Solomon SD,Alonso A,Chen LY

更新日期：2019-12-03 00:00:00