Wide Complex Tachycardia Differentiation: A Reappraisal of the State-of-the-Art.

abstract：BACKGROUND:Reactive oxygen species (ROS) are associated with development of coronary artery disease (CAD). However, there's no useful biomarker of ROS in CAD. METHODS AND RESULTS:We recruited 395 consecutive CAD patients who were performed coronary angiography (262 male and 133 female, age 70.2±10), and we measured se...

journal_title：Journal of the American Heart Association

authors： Hirata Y,Yamamoto E,Tokitsu T,Kusaka H,Fujisue K,Kurokawa H,Sugamura K,Maeda H,Tsujita K,Kaikita K,Hokimoto S,Sugiyama S,Ogawa H

更新日期：2015-01-28 00:00:00

abstract：BACKGROUND:Although a stroke event often leads to work disability, diagnoses behind work disability before and after stroke are largely unknown. We examined the pre-event and postevent trends in diagnosis-specific work disability among patients of working age. METHODS AND RESULTS:We included all new nonfatal stroke ev...

journal_title：Journal of the American Heart Association

authors： Lallukka T,Ervasti J,Lundström E,Mittendorfer-Rutz E,Friberg E,Virtanen M,Alexanderson K

更新日期：2018-01-04 00:00:00

abstract：:Background Both elemental metals and particulate air pollution have been reported to influence adult blood pressure (BP). The aim of this study is to examine which elemental components of particle mass with diameter ≤2.5 μm (PM2.5) are responsible for previously reported associations between PM2.5 and neonatal BP. Met...

journal_title：Journal of the American Heart Association

authors： Zanobetti A,Coull BA,Luttmann-Gibson H,van Rossem L,Rifas-Shiman SL,Kloog I,Schwartz JD,Oken E,Bobb JF,Koutrakis P,Gold DR

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging of carotid plaque can aid in stroke risk stratification in patients with carotid stenosis. However, the prevalence of complicated carotid plaque in patients with cryptogenic stroke is uncertain, especially as assessed by plaque imaging techniques routinely included in acute stroke ...

journal_title：Journal of the American Heart Association

authors： Gupta A,Gialdini G,Lerario MP,Baradaran H,Giambrone A,Navi BB,Marshall RS,Iadecola C,Kamel H

更新日期：2015-06-15 00:00:00

abstract：:Background Although coffee consumption is often reported as a trigger for atrial fibrillation (AF) among patients with paroxysmal AF, prospective studies on the relation of coffee consumption with AF risk have been inconsistent. Hence, we sought to assess the association between coffee consumption and risk of AF in me...

journal_title：Journal of the American Heart Association

authors： Bodar V,Chen J,Gaziano JM,Albert C,Djoussé L

更新日期：2019-08-06 00:00:00

abstract：BACKGROUND:Metabolic syndrome increases risk for atherosclerotic coronary artery disease, and its prevalence increases with increasing age and body mass index. Adults with congenital heart disease (ACHD) are now living longer and accruing coronary artery disease risk factors. However, the prevalence of metabolic syndro...

journal_title：Journal of the American Heart Association

authors： Deen JF,Krieger EV,Slee AE,Arslan A,Arterburn D,Stout KK,Portman MA

更新日期：2016-02-12 00:00:00

abstract：BACKGROUND:Sepsis may adversely affect bleeding risk in anticoagulated patients with atrial fibrillation (AF), but the impact of warfarin treatment in such patients is poorly described. This registry-based nationwide cohort study examined safety of oral anticoagulant treatment (OAC) in patients with preexisting AF who ...

journal_title：Journal of the American Heart Association

authors： Søgaard M,Skjøth F,Kjældgaard JN,Lip GYH,Larsen TB

更新日期：2017-11-09 00:00:00

abstract：BACKGROUND:Higher circulatory corin in patients with cardiac diseases is associated with improved cardiovascular outcomes, and chronic cardiac dysfunction is a well-known cause of progressive renal dysfunction. This study aimed to determine the role of serum corin in predicting short-term and long-term renal outcomes a...

journal_title：Journal of the American Heart Association

authors： Yang SF,Chou RH,Li SY,Huang SS,Huang PH

更新日期：2018-05-04 00:00:00

abstract：BACKGROUND:The volume-outcome relationship associated with intensive care unit (ICU) experience with managing acute myocardial infarction (AMI) remains inadequately understood. METHODS AND RESULTS:Within a multicenter clinical ICU database, we identified patients with a primary ICU admission diagnosis of AMI between 2...

journal_title：Journal of the American Heart Association

authors： Stolker JM,Badawi O,Spertus JA,Nasir A,Kennedy KF,Harris IH,Franey CS,Hsu VD,Ripple GR,Howell GH,Lem VM,Chan PS

更新日期：2015-06-11 00:00:00

abstract：BACKGROUND:Obesity may increase heart failure risk through cardiac remodeling. Cross-sectional associations between adiposity and cardiac structure and function have been elucidated, but the impact of longitudinal changes in adiposity on cardiac remodeling is less well understood. METHODS AND RESULTS:Participants in t...

journal_title：Journal of the American Heart Association

authors： Wilner B,Garg S,Ayers CR,Maroules CD,McColl R,Matulevicius SA,de Lemos JA,Drazner MH,Peshock R,Neeland IJ

更新日期：2017-07-19 00:00:00

abstract：:Background Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy. Current guidelines endorse management in expert centers, but patient socioeconomic status can affect access to specialty care. The effect of socioeconomic status and specialty care access on HCM outcomes has not been examined. Me...

journal_title：Journal of the American Heart Association

authors： Thomas A,Papoutsidakis N,Spatz E,Testani J,Soucier R,Chou J,Ahmad T,Darr U,Hu X,Li F,Chen ME,Bellumkonda L,Sumathipala A,Jacoby D

更新日期：2020-02-04 00:00:00

abstract：BACKGROUND:Carotid atherosclerosis (CA) is a reflector of generalized atherosclerosis that is associated with systemic vascular disease. Data are limited on the epidemiology of carotid lesions in a large, nationally representative population sample. We aimed to evaluate the prevalence of CA detected by carotid ultrason...

journal_title：Journal of the American Heart Association

authors： Wang X,Li W,Song F,Wang L,Fu Q,Cao S,Gan Y,Zhang W,Yue W,Yan F,Shi W,Wang X,Zhang H,Zhang H,Wang Z,Lu Z

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:Contemporary rates of oral anticoagulant (OAC) therapy and associated outcomes among patients undergoing percutaneous coronary intervention (PCI) have been poorly described. METHODS AND RESULTS:Using data from an integrated health care system from 2009 to 2014, we identified patients on OACs within 30 days ...

journal_title：Journal of the American Heart Association

authors： Secemsky EA,Butala NM,Kartoun U,Mahmood S,Wasfy JH,Kennedy KF,Shaw SY,Yeh RW

更新日期：2016-10-17 00:00:00

abstract：BACKGROUND:Perioperative antiplatelet agents potentially increase bleeding after non-ST-segment elevation (NSTE) acute coronary syndromes (ACS). The protease-activated receptor 1 antagonist vorapaxar reduced cardiovascular events and was associated with increased bleeding versus placebo in NSTE ACS, but its efficacy an...

journal_title：Journal of the American Heart Association

authors： van Diepen S,Tricoci P,Podder M,Westerhout CM,Aylward PE,Held C,Van de Werf F,Strony J,Wallentin L,Moliterno DJ,White HD,Mahaffey KW,Harrington RA,Armstrong PW

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Levels of LDL (low-density lipoprotein) cholesterol in the population are declining, and increasing attention is being focused on residual lipid-related pathways of atherosclerotic cardiovascular disease risk beyond LDL cholesterol. Among individuals with low (<130 mg/dL) LDL cholesterol, we undertook detail...

journal_title：Journal of the American Heart Association

authors： Lawler PR,Akinkuolie AO,Chu AY,Shah SH,Kraus WE,Craig D,Padmanabhan L,Glynn RJ,Ridker PM,Chasman DI,Mora S

更新日期：2017-07-21 00:00:00

abstract：BACKGROUND:A higher milk consumption may be associated with a lower stroke risk. We conducted a comprehensive systematic review and dose-response meta-analysis of milk and other dairy products in relation to stroke risk. METHODS AND RESULTS:Through a systematic literature search, prospective cohort studies of dairy fo...

journal_title：Journal of the American Heart Association

authors： de Goede J,Soedamah-Muthu SS,Pan A,Gijsbers L,Geleijnse JM

更新日期：2016-05-20 00:00:00

abstract：:Background The 2013 American College of Cardiology/American Heart Association cholesterol guidelines recognize cardiovascular disease and diabetes mellitus but not chronic kidney disease ( CKD ) as high-risk conditions warranting statin therapy. Statin use may be lower for adults with CKD compared with adults with con...

journal_title：Journal of the American Heart Association

authors： Mefford MT,Rosenson RS,Deng L,Tanner RM,Bittner V,Safford MM,Coll B,Mues KE,Monda KL,Muntner P

更新日期：2019-01-22 00:00:00

abstract：BACKGROUND:Vascular calcification is a common feature in patients with chronic kidney disease (CKD). CKD increases serum levels of tumor necrosis factor-α (TNFα), a critical mediator of vascular calcification. However, the molecular mechanism by which TNFα promotes CKD-dependent vascular calcification remains obscure. ...

journal_title：Journal of the American Heart Association

authors： Masuda M,Miyazaki-Anzai S,Levi M,Ting TC,Miyazaki M

更新日期：2013-09-05 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is a common, growing, and costly medical condition. We aimed to evaluate the impact of a management algorithm for symptomatic AF that used an emergency department observation unit on hospital admission rates and patient outcomes. METHODS AND RESULTS:This retrospective cohort study c...

journal_title：Journal of the American Heart Association

authors： Bellew SD,Bremer ML,Kopecky SL,Lohse CM,Munger TM,Robelia PM,Smars PA

更新日期：2016-02-08 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) is a major risk factor for cardiovascular events. We aimed to investigate the coronary plaque phenotype of diabetic patients who presented with acute coronary syndromes by optical coherence tomography. METHODS AND RESULTS:A total of 322 patients with acute coronary syndromes who under...

journal_title：Journal of the American Heart Association

authors： Sugiyama T,Yamamoto E,Bryniarski K,Xing L,Fracassi F,Lee H,Jang IK

更新日期：2018-07-13 00:00:00

abstract：BACKGROUND:Periaortic fat, because of its contiguity with the aorta, may promote vascular remodeling and aortic dilatation. However, the relations between perioartic fat depots and aortic dimensions have not been previously described. METHODS AND RESULTS:A total of 3001 individuals (mean age 50 ± 10 years, 49% women) ...

journal_title：Journal of the American Heart Association

authors： Thanassoulis G,Massaro JM,Corsini E,Rogers I,Schlett CL,Meigs JB,Hoffmann U,O'Donnell CJ,Fox CS

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Time to peak velocity (TPV) is an echocardiographic variable that can be easily measured and reflects a late peaking murmur, a classic physical finding suggesting severe aortic stenosis (AS). The aim of this study was to investigate the usefulness of TPV to evaluate AS severity. METHODS AND RESULTS:This stu...

journal_title：Journal of the American Heart Association

authors： Kamimura D,Hans S,Suzuki T,Fox ER,Hall ME,Musani SK,McMullan MR,Little WC

更新日期：2016-10-22 00:00:00

abstract：:Background To determine if accelerometer measured sedentary behavior (SED), light-intensity physical activity (LPA), and moderate-to-vigorous-intensity physical activity (MVPA) in midlife is prospectively associated with cognitive function. Methods and Results Participants were 1970 adults enrolled in the CARDIA (Coro...

journal_title：Journal of the American Heart Association

authors： Whitaker KM,Zhang D,Pettee Gabriel K,Ahrens M,Sternfeld B,Sidney S,Jacobs DR Jr,Palta P,Yaffe K

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:We previously identified peritoneal B1a cells that secrete natural IgM as a key atheroprotective B cell subset. However, the molecules that activate atheroprotective B1a cells are unknown. Here, we investigated whether Toll-like receptors (TLRs) TLR2, TLR4, and TLR9 expressed by B1a cells are required for Ig...

journal_title：Journal of the American Heart Association

authors： Hosseini H,Li Y,Kanellakis P,Tay C,Cao A,Liu E,Peter K,Tipping P,Toh BH,Bobik A,Kyaw T

更新日期：2016-11-14 00:00:00

abstract：BACKGROUND:Impaired generation and signaling of nitric oxide (NO) contribute substantially to cardiovascular (CV) risk (CVR) associated with hypertension, hyperlipidemia, and diabetes mellitus. In our rapidly aging society, advanced age is, in itself, a consistent and independent CVR factor. Many processes involved in ...

journal_title：Journal of the American Heart Association

authors： Sverdlov AL,Ngo DT,Chan WP,Chirkov YY,Horowitz JD

更新日期：2014-08-18 00:00:00

abstract：:Background Although many patients with coronary artery disease are using statins before off-pump coronary artery bypass grafting ( OPCAB ) following current guidelines, recent studies have raised concerns regarding adverse effects of preoperative statins on postoperative kidney function. We evaluated the effects of pr...

journal_title：Journal of the American Heart Association

authors： Park J,Lee JH,Kim KA,Lee SH,Lee YT,Kim WS,Min JJ

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:Although guidelines for antiarrhythmic drug therapy in atrial fibrillation (AF) were published in 2006, it remains uncertain whether adherence to these guidelines affects patient outcomes. METHODS AND RESULTS:We retrospectively evaluated the records of 5976 consecutive AF patients who were prescribed at lea...

journal_title：Journal of the American Heart Association

authors： Qin D,Leef G,Alam MB,Rattan R,Munir MB,Patel D,Khattak F,Vaghasia N,Adelstein E,Jain SK,Saba S

更新日期：2015-04-06 00:00:00

abstract：BACKGROUND:Obesity is causally associated with atherosclerosis, and adipose tissue (AT)-derived exosomes may be implicated in the metabolic complications of obesity. However, the precise role of AT-exosomes in atherogenesis remains unclear. We herein aimed to assess the effect of AT-exosomes on macrophage foam cell for...

journal_title：Journal of the American Heart Association

authors： Xie Z,Wang X,Liu X,Du H,Sun C,Shao X,Tian J,Gu X,Wang H,Tian J,Yu B

更新日期：2018-03-03 00:00:00

abstract：:Background Unruptured intracerebral aneurysm wall enhancement (AWE) on vessel wall magnetic resonance imaging scans may be a promising predictor for rupture-prone intracerebral aneurysms. However, the pathophysiology of AWE remains unclear. To this end, the association between AWE and histopathological changes was ass...

journal_title：Journal of the American Heart Association

authors： Zhong W,Su W,Li T,Tan X,Chen C,Wang Q,Wang D,Su W,Wang Y

更新日期：2021-01-19 00:00:00

abstract：:Compared with the extensive data on left-sided infective endocarditis (IE), there is much less published information on the features and management of right-sided IE. Right-sided IE accounts for 5% to 10% of all IE cases, and compared with left-sided IE, it is more often associated with intravenous drug use, intracard...

journal_title：Journal of the American Heart Association

authors： Shmueli H,Thomas F,Flint N,Setia G,Janjic A,Siegel RJ

更新日期：2020-08-04 00:00:00