Delayed Time to Peak Velocity Is Useful for Detecting Severe Aortic Stenosis.

abstract：:Background We systematically reviewed trials comparing different reperfusion strategies for ST-segment-elevation myocardial infarction and used multivariate network meta-analysis to compare outcomes across these strategies. Methods and Results We identified 31 contemporary trials in which patients with ST-segment-elev...

journal_title：Journal of the American Heart Association

authors： Fazel R,Joseph TI,Sankardas MA,Pinto DS,Yeh RW,Kumbhani DJ,Nallamothu BK

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:Chest pain is a common reason for referral to pediatric cardiologists. Although pediatric chest pain is rarely attributable to serious cardiac pathology, extensive and costly evaluation is often performed. We have implemented a standardized approach to pediatric chest pain in our pediatric cardiology clinics...

journal_title：Journal of the American Heart Association

authors： Verghese GR,Friedman KG,Rathod RH,Meiri A,Saleeb SF,Graham DA,Geggel RL,Fulton DR

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Women are more likely than men to develop resistant hypertension, which is associated with excess risk of major adverse outcomes; however, the impact of resistant hypertension in women with ischemia has not been explicitly studied. In this Women's Ischemia Syndrome Evaluation (WISE) analysis, we assessed lon...

journal_title：Journal of the American Heart Association

authors： Smith SM,Huo T,Delia Johnson B,Bittner V,Kelsey SF,Vido Thompson D,Noel Bairey Merz C,Pepine CJ,Cooper-Dehoff RM

更新日期：2014-02-28 00:00:00

abstract：:Background Hyperkalemia can be harmful, but the effect of correcting hyperkalemia is sparsely studied. We used nationwide data to examine hyperkalemia follow-up in patients with hypertension. Methods and Results We identified 7620 patients with hypertension, who had the first plasma potassium measurement ≥4.7 mmol/L (...

journal_title：Journal of the American Heart Association

authors： Krogager ML,Søgaard P,Torp-Pedersen C,Bøggild H,Gislason G,Kragholm K

更新日期：2020-12-15 00:00:00

abstract：:Background It has been suggested that endocardial and epicardial ablation of ventricular tachycardia ( VT ) improves outcome in arrhythmogenic right ventricular cardiomyopathy/dysplasia. We investigated our sequential approach for VT ablation in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia i...

journal_title：Journal of the American Heart Association

authors： Mathew S,Saguner AM,Schenker N,Kaiser L,Zhang P,Yashuiro Y,Lemes C,Fink T,Maurer T,Santoro F,Wohlmuth P,Reißmann B,Heeger CH,Tilz R,Wissner E,Rillig A,Metzner A,Kuck KH,Ouyang F

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:Participation in cardiac rehabilitation (CR) is an essential component of care for patients with coronary artery disease. However, little is known about its benefit on cardiovascular outcomes in patients with diabetes mellitus (DM) who have undergone percutaneous coronary intervention. The aim of our study w...

journal_title：Journal of the American Heart Association

authors： Jiménez-Navarro MF,Lopez-Jimenez F,Pérez-Belmonte LM,Lennon RJ,Diaz-Melean C,Rodriguez-Escudero JP,Goel K,Crusan D,Prasad A,Squires RW,Thomas RJ

更新日期：2017-10-11 00:00:00

abstract：:Background Stroke is a leading cause of death and disability in the Middle East. Data on the uptake of evidence-based practices are limited in the region. We aimed to examine patterns of stroke presentation, management, and outcomes at public Palestinian hospitals. Methods and Results Comprehensive data from all patie...

journal_title：Journal of the American Heart Association

authors： Khatib R,Jawaadah AM,Khammash U,Babiker A,Huffman MD,Prabhakaran S

更新日期：2018-11-20 00:00:00

abstract：:Background Current approaches fail to separate patients at high versus low risk for ventricular arrhythmias owing to overreliance on a snapshot left ventricular ejection fraction measure. We used statistical machine learning to identify important cardiac imaging and time-varying risk predictors. Methods and Results Th...

journal_title：Journal of the American Heart Association

authors： Wu KC,Wongvibulsin S,Tao S,Ashikaga H,Stillabower M,Dickfeld TM,Marine JE,Weiss RG,Tomaselli GF,Zeger SL

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Few studies have examined the impact of lifecourse socioeconomic position (SEP) on cardiovascular disease (CVD) risk among African Americans. METHODS AND RESULTS:We used data from the Jackson Heart Study (JHS) to examine the associations of multiple measures of lifecourse SEP with CVD events in a large coho...

journal_title：Journal of the American Heart Association

authors： Gebreab SY,Diez Roux AV,Brenner AB,Hickson DA,Sims M,Subramanyam M,Griswold ME,Wyatt SB,James SA

更新日期：2015-05-27 00:00:00

abstract：BACKGROUND:Carotid atherosclerosis (CA) is a reflector of generalized atherosclerosis that is associated with systemic vascular disease. Data are limited on the epidemiology of carotid lesions in a large, nationally representative population sample. We aimed to evaluate the prevalence of CA detected by carotid ultrason...

journal_title：Journal of the American Heart Association

authors： Wang X,Li W,Song F,Wang L,Fu Q,Cao S,Gan Y,Zhang W,Yue W,Yan F,Shi W,Wang X,Zhang H,Zhang H,Wang Z,Lu Z

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:Epidemiology of myocarditis in childhood is largely unknown. Men are known to have a higher incidence of myocarditis than women in adults aged <50 years, but whether this is true by sex in pediatric age groups is unknown. We set out to study the occurrence and potential sex differences of myocarditis in a ge...

journal_title：Journal of the American Heart Association

authors： Arola A,Pikkarainen E,Sipilä JO,Pykäri J,Rautava P,Kytö V

更新日期：2017-11-18 00:00:00

abstract：BACKGROUND:Time-limited acute stroke treatments are underused, primarily due to prehospital delay. One approach to decreasing prehospital delay is to increase stroke preparedness, the ability to recognize stroke, and the intention to immediately call emergency medical services, through community engagement with high-ri...

journal_title：Journal of the American Heart Association

authors： Skolarus LE,Zimmerman MA,Bailey S,Dome M,Murphy JB,Kobrossi C,Dombrowski SU,Burke JF,Morgenstern LB

更新日期：2016-05-20 00:00:00

abstract：:Background Systemic innate immune priming is a recognized sequela of post-ischemic neuroinflammation and contributor to delayed neurodegeneration. Given mounting evidence linking acute stroke with reactive lung inflammation, we asked whether enhanced expression of the endogenous antioxidant extracellular superoxide di...

journal_title：Journal of the American Heart Association

authors： Mai N,Miller-Rhodes K,Prifti V,Kim M,O'Reilly MA,Halterman MW

更新日期：2019-05-07 00:00:00

abstract：:Background Sepsis is the overwhelming host response to infection leading to shock and multiple organ dysfunction. Cardiovascular complications greatly increase sepsis-associated mortality. Although murine models are routinely used for preclinical studies, the benefit of using genetically engineered mice in sepsis is c...

journal_title：Journal of the American Heart Association

authors： Hoffman M,Kyriazis ID,Lucchese AM,de Lucia C,Piedepalumbo M,Bauer M,Schulze PC,Bonios MJ,Koch WJ,Drosatos K

更新日期：2019-05-21 00:00:00

abstract：BACKGROUND:Increasing evidence has suggested that major depression (MD) is associated with an increased risk of ischemic heart disease (IHD). We examined this association in Chinese adults using data from the China Kadoorie Biobank study. METHODS AND RESULTS:Over 0.5 million adults aged 30 to 79 years were followed fr...

journal_title：Journal of the American Heart Association

authors： Liu N,Pan XF,Yu C,Lv J,Guo Y,Bian Z,Yang L,Chen Y,Wu T,Chen Z,Pan A,Li L,China Kadoorie Biobank Collaborative Group.

更新日期：2016-12-21 00:00:00

abstract：BACKGROUND:Postural tachycardia syndrome (POTS) is a disorder of chronic orthostatic intolerance accompanied by excessive orthostatic tachycardia. Patients with POTS commonly have comorbid conditions such as attention deficit hyperactivity disorder, depression, or fibromyalgia that are treated with medications that inh...

journal_title：Journal of the American Heart Association

authors： Green EA,Raj V,Shibao CA,Biaggioni I,Black BK,Dupont WD,Robertson D,Raj SR

更新日期：2013-09-03 00:00:00

abstract：BACKGROUND:Quercetin, the most abundant dietary flavonol, has antioxidant effects in cardiovascular disease, but the evidence regarding its effects on blood pressure (BP) has not been conclusive. We assessed the impact of quercetin on BP through a systematic review and meta-analysis of available randomized controlled t...

journal_title：Journal of the American Heart Association

authors： Serban MC,Sahebkar A,Zanchetti A,Mikhailidis DP,Howard G,Antal D,Andrica F,Ahmed A,Aronow WS,Muntner P,Lip GY,Graham I,Wong N,Rysz J,Banach M,Lipid and Blood Pressure Meta‐analysis Collaboration (LBPMC) Group.

更新日期：2016-07-12 00:00:00

abstract：BACKGROUND:Fatty infiltration of the pancreas is an enigmatic manifestation of ectopic fat deposition in obesity. Studies have shown that pancreatic lipid accumulation interferes with insulin secretion in humans. However, the prevalence of fatty pancreas and its associated factors in the general population remain uncle...

journal_title：Journal of the American Heart Association

authors： Wang CY,Ou HY,Chen MF,Chang TC,Chang CJ

更新日期：2014-02-26 00:00:00

abstract：BACKGROUND:Cryoballoon pulmonary vein isolation (PVI) has emerged as an alternative to radiofrequency PVI for atrial fibrillation (AF). Data are lacking to define the rates and predictors of complications, particularly phrenic nerve injury (PNI). METHODS AND RESULTS:We evaluated a single-center prospective registry of...

journal_title：Journal of the American Heart Association

authors： Guhl EN,Siddoway D,Adelstein E,Bazaz R,Mendenhall GS,Nemec J,Saba S,Schwartzman D,Voigt A,Wang NC,Jain SK

更新日期：2016-07-21 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) is a common condition associated with cardiovascular disease. Its potential effect on progression of subclinical atherosclerosis is not well understood. We tested the hypothesis that self-reported OSA is associated with progression of coronary artery calcium (CAC). We also evalu...

journal_title：Journal of the American Heart Association

authors： Kwon Y,Duprez DA,Jacobs DR,Nagayoshi M,McClelland RL,Shahar E,Budoff M,Redline S,Shea S,Carr JJ,Lutsey PL

更新日期：2014-09-26 00:00:00

abstract：BACKGROUND:Cardiac sodium channel (NaV1.5) dysfunction contributes to arrhythmogenesis during pathophysiological conditions. Nav1.5 localizes to distinct subcellular microdomains within the cardiomyocyte, where it associates with region-specific proteins, yielding complexes whose function is location specific. We herei...

journal_title：Journal of the American Heart Association

authors： Rivaud MR,Agullo-Pascual E,Lin X,Leo-Macias A,Zhang M,Rothenberg E,Bezzina CR,Delmar M,Remme CA

更新日期：2017-12-08 00:00:00

abstract：:Background Recent literature reports a strong thrombotic tendency in patients hospitalized for a coronavirus disease 2019 (COVID-19) infection. This characteristic is unusual and seems specific to COVID-19 infections, especially in their severe form. Viral infections can trigger acquired thrombophilia, which can then ...

journal_title：Journal of the American Heart Association

authors： Ferrari E,Sartre B,Squara F,Contenti J,Occelli C,Lemoel F,Levraut J,Doyen D,Dellamonica J,Mondain V,Chirio D,Risso K,Cua E,Orban JC,Ichai C,Labbaoui M,Mossaz B,Moceri P,Appert-Flory A,Fischer F,Toulon P

更新日期：2020-11-03 00:00:00

abstract：:Background Cardiovascular disease incidence, prevalence, morbidity, and mortality have declined in the past several decades; however, disparities persist among subsets of the population. Notably, blacks have not experienced the same improvements on the whole as whites. Furthermore, frequent reports of relatively poore...

journal_title：Journal of the American Heart Association

authors： Islam SJ,Kim JH,Topel M,Liu C,Ko YA,Mujahid MS,Sims M,Mubasher M,Ejaz K,Morgan-Billingslea J,Jones K,Waller EK,Jones D,Uppal K,Dunbar SB,Pemu P,Vaccarino V,Searles CD,Baltrus P,Lewis TT,Quyyumi AA,Taylor H

更新日期：2020-05-05 00:00:00

abstract：:Background The 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines lowered the threshold of blood pressure (BP) for hypertension to 130/80 mm Hg. However, the clinical significance of isolated diastolic hypertension (IDH) according to the cutoff value of the 2017 ACC/AHA guidelines wa...

journal_title：Journal of the American Heart Association

authors： Kaneko H,Itoh H,Yotsumoto H,Kiriyama H,Kamon T,Fujiu K,Morita K,Michihata N,Jo T,Takeda N,Morita H,Yasunaga H,Komuro I

更新日期：2020-10-20 00:00:00

abstract：:Background Myocardial infarction (MI) size is a key predictor of prognosis in post-MI patients. Cardiovascular magnetic resonance (CMR) is the gold standard test for MI quantification, but the ECG is less expensive and more widely available. We sought to quantify the relationship between ECG markers and cardiovascular...

journal_title：Journal of the American Heart Association

authors： Lee DC,Albert CM,Narula D,Kadish AH,Panicker GK,Wu E,Schaechter A,Pester J,Chatterjee NA,Cook NR,Goldberger JJ

更新日期：2020-02-04 00:00:00

abstract：BACKGROUND:Bromocriptine-QR (a quick-release formulation of bromocriptine mesylate), a dopamine D2 receptor agonist, is a US Food and Drug Administrration-approved treatment for type 2 diabetes mellitus (T2DM). A 3070-subject randomized trial demonstrated a significant, 40% reduction in relative risk among bromocriptin...

journal_title：Journal of the American Heart Association

authors： Gaziano JM,Cincotta AH,Vinik A,Blonde L,Bohannon N,Scranton R

更新日期：2012-10-01 00:00:00

abstract：:Background Although coffee consumption is often reported as a trigger for atrial fibrillation (AF) among patients with paroxysmal AF, prospective studies on the relation of coffee consumption with AF risk have been inconsistent. Hence, we sought to assess the association between coffee consumption and risk of AF in me...

journal_title：Journal of the American Heart Association

authors： Bodar V,Chen J,Gaziano JM,Albert C,Djoussé L

更新日期：2019-08-06 00:00:00

abstract：:Background Atrial fibrillation (AF) is associated with cognitive decline. Whether left atrial enlargement (LAE), a critical substrate for AF, is also associated is less well established. Therefore, we assessed the association of LAE and AF with cognitive decline in the ARIC-NCS (Atherosclerosis Risk in Communities Neu...

journal_title：Journal of the American Heart Association

authors： Zhang MJ,Norby FL,Lutsey PL,Mosley TH,Cogswell RJ,Konety SH,Chao TF,Shah AM,Solomon SD,Alonso A,Chen LY

更新日期：2019-12-03 00:00:00

abstract：:Background Young women with coronary artery disease ( CAD ), a group with high psychosocial burden, were previously shown to have higher levels of interleukin-6 ( IL -6) compared with men of similar age. We sought to examine IL -6 response to acute stress in CAD patients across sex and age, and contrast results to hea...

journal_title：Journal of the American Heart Association

authors： Sullivan S,Hammadah M,Wilmot K,Ramadan R,Pearce BD,Shah A,Kaseer B,Gafeer MM,Lima BB,Kim JH,Ward L,Ko YA,Lewis TT,Hankus A,Elon L,Li L,Bremner JD,Raggi P,Quyyumi A,Vaccarino V

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:Elevated serum phosphorus might aggravate the effect of hypertension on mortality. The objective of this study was to examine the joint effect of hypertension and serum phosphorus on the risk of mortality. METHODS AND RESULTS:A large prospective (n=15 833), population-based cohort of participants from the N...

journal_title：Journal of the American Heart Association

authors： Vart P,Nigatu YT,Jaglan A,van Zon SK,Shafique K

更新日期：2015-05-20 00:00:00