Enigmatic ectopic fat: prevalence of nonalcoholic fatty pancreas disease and its associated factors in a Chinese population.

abstract：BACKGROUND:Medication adherence improves outcomes for patients with heart failure, but adherence rates remain low. We examined the association between earlier postdischarge follow-up and medication adherence. METHODS AND RESULTS:We performed a retrospective cohort study of patients ≥65 years who were hospitalized for ...

journal_title：Journal of the American Heart Association

authors： Chang LL,Xu H,DeVore AD,Matsouaka RA,Yancy CW,Fonarow GC,Allen LA,Hernandez AF

更新日期：2018-04-01 00:00:00

abstract：:Background We systematically reviewed trials comparing different reperfusion strategies for ST-segment-elevation myocardial infarction and used multivariate network meta-analysis to compare outcomes across these strategies. Methods and Results We identified 31 contemporary trials in which patients with ST-segment-elev...

journal_title：Journal of the American Heart Association

authors： Fazel R,Joseph TI,Sankardas MA,Pinto DS,Yeh RW,Kumbhani DJ,Nallamothu BK

更新日期：2020-06-16 00:00:00

abstract：:Background Atrial fibrillation (AF) has been shown to be associated with an increased risk of dementia as well as Alzheimer disease in observational studies. Whether this association reflects causal association is still unclear. The purpose of this study was to examine the causal association of AF with Alzheimer disea...

journal_title：Journal of the American Heart Association

authors： Pan Y,Wang Y,Wang Y

更新日期：2020-01-21 00:00:00

abstract：:Background This study was performed to characterize the metabolic, functional, and structural cardiac changes in a canine model of radiation-induced heart disease by serial in vivo imaging and ex vivo analyses. Methods and Results Thirty-six dogs were randomly assigned to control or irradiated groups at 3 time points ...

journal_title：Journal of the American Heart Association

authors： Yan R,Li X,Song J,Guo M,Cai H,Wu Z,Wu P,Li L,Yang M,Wang Y,Li S

更新日期：2020-09-15 00:00:00

abstract：:Background For patients with ST-segment-elevation myocardial infarction (STEMI) and multivessel coronary artery disease, the optimal treatment of the non-infarct-related artery has been controversial. This up-to-date meta-analysis focusing on individual clinical end points was performed to further evaluate the benefit...

journal_title：Journal of the American Heart Association

authors： Ahmad Y,Howard JP,Arnold A,Prasad M,Seligman H,Cook CM,Warisawa T,Shun-Shun M,Ali Z,Parikh MA,Al-Lamee R,Sen S,Francis D,Moses JW,Leon MB,Stone GW,Karmpaliotis D

更新日期：2020-06-16 00:00:00

abstract：BACKGROUND:Oxidative stress is implicated in the etiology of coronary heart disease (CHD). New measures to capture oxidative stress are warranted. Fluorescent oxidation products (FlOPs) can be measured in plasma and have been shown to reflect levels of oxidative stress and to predict risk of CHD in men over 6 years of ...

journal_title：Journal of the American Heart Association

authors： Jensen MK,Wang Y,Rimm EB,Townsend MK,Willett W,Wu T

更新日期：2013-10-08 00:00:00

abstract：:Background Norwood surgery provides a palliative surgical option for hypoplastic left heart syndrome and has been available in Sweden since 1993. The practice of prenatal ultrasound screening was gradually implemented in the same era, resulting in an increased prenatal detection rate. Our primary aims were to study ch...

journal_title：Journal of the American Heart Association

authors： Öhman A,El-Segaier M,Bergman G,Hanséus K,Malm T,Nilsson B,Pivodic A,Rydberg A,Sonesson SE,Mellander M

更新日期：2019-01-22 00:00:00

abstract：BACKGROUND:Currently, acute ischemic stroke is still a leading cause of mortality and morbidity. Approximately 2 years ago, mechanical thrombectomy was proven beneficial as a revolutionary new therapy for stroke in the MR-CLEAN trial (A Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic ...

journal_title：Journal of the American Heart Association

authors： Autar ASA,Hund HM,Ramlal SA,Hansen D,Lycklama À Nijeholt GJ,Emmer BJ,de Maat MPM,Dippel DWJ,van der Lugt A,van Es ACGM,van Beusekom HMM,MR CLEAN Registry Investigators.

更新日期：2018-06-22 00:00:00

abstract：BACKGROUND:Multiple studies have shown that an NO-induced activation of vascular smooth muscle BK channels contributes to the NO-evoked dilation in many blood vessels. In vivo, NO is released continuously. NO attenuates vessel constrictions and, therefore, exerts an anticontractile effect. It is unknown whether the ant...

journal_title：Journal of the American Heart Association

authors： Schmid J,Müller B,Heppeler D,Gaynullina D,Kassmann M,Gagov H,Mladenov M,Gollasch M,Schubert R

更新日期：2018-03-24 00:00:00

abstract：:Background Hypertensive myocardial fibrosis (MF) is characterized by excessive deposition of extracellular matrix and cardiac fibroblast proliferation, which can lead to heart failure, malignant arrhythmia, and sudden death. In recent years, with the deepening of research, microRNAs have been found to have an importan...

journal_title：Journal of the American Heart Association

authors： Zhang W,Wang Q,Feng Y,Chen X,Yang L,Xu M,Wang X,Li W,Niu X,Gao D

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Conflicting findings of the association between serum uric acid (UA) and stroke have been reported in both men and women, and it is unclear whether this association was different between men and women. We preformed this meta-analysis to assess the sex-specific effect of serum UA on the risk of stroke and its...

journal_title：Journal of the American Heart Association

authors： Zhong C,Zhong X,Xu T,Xu T,Zhang Y

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether reducing plasma homocysteine concentrations with long-term, combined treatment with folic acid, vitamin B6, and vitamin B12 alters plasma biomarkers of inflammation and endothelial dysfunction in women at increased risk of cardiovascular disease. METHODS AND RE...

journal_title：Journal of the American Heart Association

authors： Christen WG,Cook NR,Van Denburgh M,Zaharris E,Albert CM,Manson JE

更新日期：2018-05-18 00:00:00

abstract：BACKGROUND:Ischemic stroke is a major cause of death and disability in the world. A major ischemic stroke subtype, large-vessel ischemic stroke (large artery atherosclerosis; LAA), has been shown to have some genetic components in individuals of European ancestry. However, it is not clear whether the genetic predisposi...

journal_title：Journal of the American Heart Association

authors： Lee TH,Ko TM,Chen CH,Lee MT,Chang YJ,Chang CH,Huang KL,Chang TY,Lee JD,Chang KC,Yang JT,Wen MS,Wang CY,Chen YT,Hsieh CS,Chou SY,Liu YM,Chen HW,Liao HT,Wang CW,Chen SP,Lu LS,Chen YT,Wu JY

更新日期：2016-03-29 00:00:00

abstract：:Background Expression of receptor for advanced glycation end products (RAGE) plays an important role in diabetic peripheral artery disease. We proposed to show that treatment with an antibody blocking RAGE would improve hind limb perfusion and muscle viability in diabetic pig with femoral artery (FA) ligation. Methods...

journal_title：Journal of the American Heart Association

authors： Johnson LL,Johnson J,Ober R,Holland A,Zhang G,Backer M,Backer J,Ali Z,Tekabe Y

更新日期：2021-01-05 00:00:00

abstract：BACKGROUND:Extracorporeal cardiopulmonary resuscitation (ECPR) is widely proposed for the treatment of refractory cardiac arrest. It should be associated with coronary angiography if coronary artery disease is suspected. However, the prioritization of care remains unclear in this situation. Our goal was to determine wh...

journal_title：Journal of the American Heart Association

authors： Hutin A,Lamhaut L,Lidouren F,Kohlhauer M,Mongardon N,Carli P,Berdeaux A,Ghaleh B,Tissier R

更新日期：2016-12-22 00:00:00

abstract：:Background Data on race- and ethnicity-based disparities in the utilization and outcomes of structural heart disease interventions in the United States are scarce. Methods and Results We used the National Inpatient Sample (2011-2016) to examine racial and ethnic differences in the utilization, in-hospital outcomes, an...

journal_title：Journal of the American Heart Association

authors： Alkhouli M,Alqahtani F,Holmes DR,Berzingi C

更新日期：2019-08-06 00:00:00

abstract：:Background Coronary artery disease remains a major cause of death despite better outcomes of ST-segment-elevation myocardial infarction (STEMI). We aimed to analyze data from the Ruti-STEMI registry of in-hospital, 28-day, and 1-year events in patients with STEMI over the past 3 decades in Catalonia, Spain, to assess ...

journal_title：Journal of the American Heart Association

authors： García-García C,Oliveras T,Serra J,Vila J,Rueda F,Cediel G,Labata C,Ferrer M,Carrillo X,Dégano IR,De Diego O,El Ouaddi N,Montero S,Mauri J,Elosua R,Lupón J,Bayes-Genis A,Ruti‐STEMI Investigators †.

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Epidemiology of myocarditis in childhood is largely unknown. Men are known to have a higher incidence of myocarditis than women in adults aged <50 years, but whether this is true by sex in pediatric age groups is unknown. We set out to study the occurrence and potential sex differences of myocarditis in a ge...

journal_title：Journal of the American Heart Association

authors： Arola A,Pikkarainen E,Sipilä JO,Pykäri J,Rautava P,Kytö V

更新日期：2017-11-18 00:00:00

abstract：:Background Although many patients with coronary artery disease are using statins before off-pump coronary artery bypass grafting ( OPCAB ) following current guidelines, recent studies have raised concerns regarding adverse effects of preoperative statins on postoperative kidney function. We evaluated the effects of pr...

journal_title：Journal of the American Heart Association

authors： Park J,Lee JH,Kim KA,Lee SH,Lee YT,Kim WS,Min JJ

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:Perioperative antiplatelet agents potentially increase bleeding after non-ST-segment elevation (NSTE) acute coronary syndromes (ACS). The protease-activated receptor 1 antagonist vorapaxar reduced cardiovascular events and was associated with increased bleeding versus placebo in NSTE ACS, but its efficacy an...

journal_title：Journal of the American Heart Association

authors： van Diepen S,Tricoci P,Podder M,Westerhout CM,Aylward PE,Held C,Van de Werf F,Strony J,Wallentin L,Moliterno DJ,White HD,Mahaffey KW,Harrington RA,Armstrong PW

更新日期：2015-12-15 00:00:00

abstract：:Background Duchenne muscular dystrophy (DMD) is a neuromuscular disorder caused by mutations within the dystrophin gene. DMD is characterized by progressive skeletal muscle degeneration and atrophy and progressive cardiomyopathy. It has been observed the severity of cardiomyopathy varies in patients with DMD. Methods ...

journal_title：Journal of the American Heart Association

authors： Jiang X,Shao Y,Araj FG,Amin AA,Greenberg BM,Drazner MH,Xing C,Mammen PPA

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:In 2009, the Get With The Guidelines-Stroke (GWTG-Stroke) program offered additional recognition if hospitals performed well on certain stroke quality measures. We sought to determine whether quality of care for all hospitals participating in GWTG-Stroke improved with this expanded recognition program. METH...

journal_title：Journal of the American Heart Association

authors： Heidenreich PA,Zhao X,Hernandez AF,Schwamm LH,Smith E,Reeves M,Peterson ED,Fonarow GC

更新日期：2017-01-21 00:00:00

abstract：BACKGROUND:Quercetin, the most abundant dietary flavonol, has antioxidant effects in cardiovascular disease, but the evidence regarding its effects on blood pressure (BP) has not been conclusive. We assessed the impact of quercetin on BP through a systematic review and meta-analysis of available randomized controlled t...

journal_title：Journal of the American Heart Association

authors： Serban MC,Sahebkar A,Zanchetti A,Mikhailidis DP,Howard G,Antal D,Andrica F,Ahmed A,Aronow WS,Muntner P,Lip GY,Graham I,Wong N,Rysz J,Banach M,Lipid and Blood Pressure Meta‐analysis Collaboration (LBPMC) Group.

更新日期：2016-07-12 00:00:00

abstract：BACKGROUND:Studies have suggested that complete revascularization is superior to culprit-only revascularization for the treatment of enzyme-positive acute coronary syndrome. However, the optimal timing of complete revascularization remains unclear. We conducted a systematic review and meta-analysis of randomized contro...

journal_title：Journal of the American Heart Association

authors： Gaffar R,Habib B,Filion KB,Reynier P,Eisenberg MJ

更新日期：2017-04-10 00:00:00

abstract：:Background Recent evidence suggests that racial/ethnic differences in circulating levels of free or bioavailable 25-hydroxy vitamin D (25[ OH ]D) rather than total 25( OH )D may explain apparent racial disparities in cardiovascular disease ( CVD ). We prospectively examined black-white differences in the associations ...

journal_title：Journal of the American Heart Association

authors： Zhang X,Tu W,Manson JE,Tinker L,Liu S,Cauley JA,Qi L,Mouton C,Martin LW,Hou L,Song Y

更新日期：2019-02-19 00:00:00

abstract：:Background Among people with lower extremity peripheral artery disease, obesity is associated with faster functional decline than normal weight. The association of weight loss with functional decline in peripheral artery disease is unknown. Methods and Results Adults with an ankle-brachial index <0.90 were identified ...

journal_title：Journal of the American Heart Association

authors： Polonsky TS,Tian L,Zhang D,Bazzano LA,Criqui MH,Ferrucci L,Guralnik JM,Kibbe MR,Leeuwenburgh C,Sufit RL,McDermott MM

更新日期：2019-07-02 00:00:00

abstract：BACKGROUND:Cardiac mesenchymal cell (CMC) administration improves cardiac function in animal models of heart failure. Although the precise mechanisms remain unclear, transdifferentiation and paracrine signaling are suggested to underlie their cardiac reparative effects. We have shown that histone deacetylase 1 (HDAC1) ...

journal_title：Journal of the American Heart Association

authors： Moore JB 4th,Zhao J,Fischer AG,Keith MCL,Hagan D,Wysoczynski M,Bolli R

更新日期：2017-07-05 00:00:00

abstract：BACKGROUND:Pulse pressure (PP) is related to cardiac function, arterial stiffness, fluid status, and vascular events. This study aimed to explore the prognostic role of PP upon admission in patients with acute ischemic stroke (AIS) based on a nation-wide stroke registry. METHODS AND RESULTS:We evaluated the associatio...

journal_title：Journal of the American Heart Association

authors： Tang SC,Yin JH,Liu CH,Sun MH,Lee JT,Sun Y,Hsu CS,Sun MC,Lin CH,Chen CH,Lien LM,Muo CH,Jeng JS,Hsu CY,Taiwan Stroke Registry Investigators.

更新日期：2017-06-22 00:00:00

abstract：BACKGROUND:Our previous randomized controlled trial demonstrated cardiorespiratory protection by remote ischemic preconditioning (RIPC) in children before cardiac surgery. However, the impact of RIPC on myocardial prosurvival intracellular signaling remains unknown in cyanosis. RIPC may augment phosphorylated protein s...

journal_title：Journal of the American Heart Association

authors： Pepe S,Liaw NY,Hepponstall M,Sheeran FL,Yong MS,d'Udekem Y,Cheung MM,Konstantinov IE

更新日期：2013-05-10 00:00:00

abstract：BACKGROUND:Despite guideline recommendations, a significant number of patients with non-ST elevation myocardial infarction (NSTEMI) do not receive dual antiplatelet therapy (DAPT) before angiography "pretreatment." While there may be valid clinical reasons to not pretreat, such as concern for bleeding or multivessel di...

journal_title：Journal of the American Heart Association

authors： Shafiq A,Valle J,Jang JS,Qintar M,Gosch K,Cohen DJ,Singh M,Bach R,Spertus JA

更新日期：2016-06-10 00:00:00