High-Resolution Imaging of Interaction Between Thrombus and Stent-Retriever in Patients With Acute Ischemic Stroke.

abstract：:Background In complex congenital heart disease patients such as those with tetralogy of Fallot, the right ventricle (RV) is subject to pressure overload, leading to RV hypertrophy and eventually RV failure. The mechanisms that promote the transition from stable RV hypertrophy to RV failure are unknown. We evaluated th...

journal_title：Journal of the American Heart Association

authors： Hwang HV,Sandeep N,Nair RV,Hu DQ,Zhao M,Lan IS,Fajardo G,Matkovich SJ,Bernstein D,Reddy S

更新日期：2021-01-30 00:00:00

abstract：BACKGROUND:Galectin-3 may play a role in cardiac and noncardiac fibrosis, and elevated circulating levels of this protein predict adverse outcomes in patients with heart failure who do not have congenital heart disease. We investigated galectin-3 in adults with single-ventricle Fontan circulation, patients who are pron...

journal_title：Journal of the American Heart Association

authors： Opotowsky AR,Baraona F,Owumi J,Loukas B,Singh MN,Valente AM,Wu F,Cheng S,Veldtman G,Rimm EB,Landzberg MJ

更新日期：2016-01-11 00:00:00

abstract：BACKGROUND:We examined the role of menopause on cardiac dimensions and function and assessed the efficacy of exercise training before and after menopause. METHODS AND RESULTS:Two groups of healthy premenopausal (n=36, 49.4±0.3 years) and postmenopausal (n=37, 53.5±0.5 years) women with no history of cardiovascular dis...

journal_title：Journal of the American Heart Association

authors： Egelund J,Jørgensen PG,Mandrup CM,Fritz-Hansen T,Stallknecht B,Bangsbo J,Nyberg M,Hellsten Y

更新日期：2017-08-18 00:00:00

abstract：:Background Malnutrition is one of the most important comorbidities in patients with heart failure with preserved ejection fraction. We recently reported the prognostic significance of serum cholinesterase level and superior predictive power of cholinesterase level to other objective nutritional indices such as the con...

journal_title：Journal of the American Heart Association

authors： Seo M,Yamada T,Tamaki S,Hikoso S,Yasumura Y,Higuchi Y,Nakagawa Y,Uematsu M,Abe H,Fuji H,Mano T,Nakatani D,Fukunami M,Sakata Y

更新日期：2020-01-07 00:00:00

abstract：:Background The objectives of the present study were (1) to evaluate the echocardiographic prognostic factors associated with improved left ventricular (LV) systolic function after aortic valve replacement, and (2) to compare the long-term outcomes after aortic valve replacement in chronic aortic regurgitation (AR) pat...

journal_title：Journal of the American Heart Association

authors： Kim MS,Kim JH,Joo HC,Lee S,Youn YN,Lee SH

更新日期：2020-12-15 00:00:00

abstract：BACKGROUND:Obesity is causally associated with atherosclerosis, and adipose tissue (AT)-derived exosomes may be implicated in the metabolic complications of obesity. However, the precise role of AT-exosomes in atherogenesis remains unclear. We herein aimed to assess the effect of AT-exosomes on macrophage foam cell for...

journal_title：Journal of the American Heart Association

authors： Xie Z,Wang X,Liu X,Du H,Sun C,Shao X,Tian J,Gu X,Wang H,Tian J,Yu B

更新日期：2018-03-03 00:00:00

abstract：:Background The purpose of this study was to determine whether the presence of antegrade blood flow was related to stroke subtype in patients with acute intracranial large artery occlusion. Methods and Results The prospectively collected data for consecutive patients who had occlusion of the unilateral M1 segment of th...

journal_title：Journal of the American Heart Association

authors： Zhang M,Chen Z,Xu J,Gong X,Shi F,Lou M

更新日期：2020-10-20 00:00:00

abstract：:Background Limited data are available on the prospective relationship between beverage consumption and plasma lipid and lipoprotein concentrations. Two major sources of sugar in the US diet are sugar-sweetened beverages (SSBs) and 100% fruit juices. Low-calorie sweetened beverages are common replacements. Methods and ...

journal_title：Journal of the American Heart Association

authors： Haslam DE,Peloso GM,Herman MA,Dupuis J,Lichtenstein AH,Smith CE,McKeown NM

更新日期：2020-03-03 00:00:00

abstract：BACKGROUND:Excess accumulation of abdominal subcutaneous (SAT) and visceral adipose tissue (VAT) is associated with adverse levels of adipokines and cardiovascular disease risk. Whether fat quality is associated with adipokines has not been firmly established. This study examined the association between abdominal SAT a...

journal_title：Journal of the American Heart Association

authors： Lee JJ,Pedley A,Hoffmann U,Massaro JM,Keaney JF Jr,Vasan RS,Fox CS

更新日期：2016-02-29 00:00:00

abstract：:Background Cardiovascular disease incidence, prevalence, morbidity, and mortality have declined in the past several decades; however, disparities persist among subsets of the population. Notably, blacks have not experienced the same improvements on the whole as whites. Furthermore, frequent reports of relatively poore...

journal_title：Journal of the American Heart Association

authors： Islam SJ,Kim JH,Topel M,Liu C,Ko YA,Mujahid MS,Sims M,Mubasher M,Ejaz K,Morgan-Billingslea J,Jones K,Waller EK,Jones D,Uppal K,Dunbar SB,Pemu P,Vaccarino V,Searles CD,Baltrus P,Lewis TT,Quyyumi AA,Taylor H

更新日期：2020-05-05 00:00:00

abstract：:The primary goal of the initial ECG evaluation of every wide complex tachycardia is to determine whether the tachyarrhythmia has a ventricular or supraventricular origin. The answer to this question drives immediate patient care decisions, ensuing clinical workup, and long-term management strategies. Thus, the importa...

journal_title：Journal of the American Heart Association

authors： Kashou AH,Noseworthy PA,DeSimone CV,Deshmukh AJ,Asirvatham SJ,May AM

更新日期：2020-06-02 00:00:00

abstract：:Background We evaluated a community-engaged stroke preparedness intervention that aimed to increase early hospital arrival and emergency medical services (EMS) utilization among patients with stroke in the South Side of Chicago, Illinois. Methods and Results We compared change in early hospital arrival (<3 hours from ...

journal_title：Journal of the American Heart Association

authors： Prabhakaran S,Richards CT,Kwon S,Wymore E,Song S,Eisenstein A,Brown J,Kandula NR,Mason M,Beckstrom H,Washington KV,Aggarwal NT

更新日期：2020-09-15 00:00:00

abstract：:Background To determine if accelerometer measured sedentary behavior (SED), light-intensity physical activity (LPA), and moderate-to-vigorous-intensity physical activity (MVPA) in midlife is prospectively associated with cognitive function. Methods and Results Participants were 1970 adults enrolled in the CARDIA (Coro...

journal_title：Journal of the American Heart Association

authors： Whitaker KM,Zhang D,Pettee Gabriel K,Ahrens M,Sternfeld B,Sidney S,Jacobs DR Jr,Palta P,Yaffe K

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:Orthostatic hypotension causes ≈80 000 hospitalizations per year in the United States. Treatments for orthostatic hypotension include fludrocortisone, a mineralocorticoid analog that promotes sodium reabsorption; and midodrine, an α-1 adrenergic agonist that is a direct vasoconstrictor. Although both medicat...

journal_title：Journal of the American Heart Association

authors： Grijalva CG,Biaggioni I,Griffin MR,Shibao CA

更新日期：2017-10-12 00:00:00

abstract：BACKGROUND:Vascular proliferative diseases such as atherosclerosis are inflammatory disorders involving multiple cell types including macrophages, lymphocytes, endothelial cells, and smooth muscle cells (SMCs). Although activation of the nuclear factor-κB (NF-κB) pathway in vessels has been shown to be critical for the...

journal_title：Journal of the American Heart Association

authors： Yoshida T,Yamashita M,Horimai C,Hayashi M

更新日期：2013-05-23 00:00:00

abstract：BACKGROUND:Experimental studies demonstrate that high aortic pressure in late systole relative to early systole causes greater myocardial remodeling and dysfunction, for any given absolute peak systolic pressure. METHODS AND RESULTS:We tested the hypothesis that late systolic hypertension, defined as the ratio of late...

journal_title：Journal of the American Heart Association

authors： Chirinos JA,Segers P,Duprez DA,Brumback L,Bluemke DA,Zamani P,Kronmal R,Vaidya D,Ouyang P,Townsend RR,Jacobs DR Jr

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:Microvascular injury (MVI) after primary percutaneous coronary intervention for ST-elevation myocardial infarction (STEMI) is a major determinant of adverse clinical outcome. Experimental data indicate an impact of hypercholesterolemia on MVI; however, there is a lack of clinical studies confirming this rela...

journal_title：Journal of the American Heart Association

authors： Reindl M,Reinstadler SJ,Feistritzer HJ,Theurl M,Basic D,Eigler C,Holzknecht M,Mair J,Mayr A,Klug G,Metzler B

更新日期：2017-10-10 00:00:00

abstract：BACKGROUND:Many patients requiring a pacemaker have persistent hypertension with systolic blood pressures above recommended levels. We evaluated a pacemaker-based Programmable Hypertension Control (PHC) therapy that uses a sequence of variably timed shorter and longer atrioventricular intervals. METHODS AND RESULTS:Pa...

journal_title：Journal of the American Heart Association

authors： Neuzil P,Merkely B,Erglis A,Marinskis G,de Groot JR,Schmidinger H,Rodriguez Venegas M,Voskuil M,Sturmberger T,Petru J,Jongejan N,Aichinger J,Kamzola G,Aidietis A,Gellér L,Mraz T,Osztheimer I,Mika Y,Evans S,Burkhoff

更新日期：2017-12-23 00:00:00

abstract：:Background Arterial stiffness is an independent risk factor for cardiovascular disease and can be beneficially influenced by physical activity. However, it is not clear how an individual's physical activity pattern over a week is associated with arterial stiffness. Therefore, we examined the associations of the amount...

journal_title：Journal of the American Heart Association

authors： Vandercappellen EJ,Henry RMA,Savelberg HHCM,van der Berg JD,Reesink KD,Schaper NC,Eussen SJPM,van Dongen MCJM,Dagnelie PC,Schram MT,van Greevenbroek MMJ,Wesselius A,van der Kallen CJH,Köhler S,Stehouwer CDA,Koster A

更新日期：2020-10-20 00:00:00

abstract：:Background Unruptured intracerebral aneurysm wall enhancement (AWE) on vessel wall magnetic resonance imaging scans may be a promising predictor for rupture-prone intracerebral aneurysms. However, the pathophysiology of AWE remains unclear. To this end, the association between AWE and histopathological changes was ass...

journal_title：Journal of the American Heart Association

authors： Zhong W,Su W,Li T,Tan X,Chen C,Wang Q,Wang D,Su W,Wang Y

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND:Weight loss is associated with improvements in cardiometabolic risk factors, including serum glucose, insulin, C-reactive protein, and blood lipids. Few studies have evaluated the long-term (>18 months) effect of weight loss on these risk factors or sought to identify factors associated with sustained improv...

journal_title：Journal of the American Heart Association

authors： Dow CA,Thomson CA,Flatt SW,Sherwood NE,Pakiz B,Rock CL

更新日期：2013-12-18 00:00:00

abstract：BACKGROUND:Contemporary rates of oral anticoagulant (OAC) therapy and associated outcomes among patients undergoing percutaneous coronary intervention (PCI) have been poorly described. METHODS AND RESULTS:Using data from an integrated health care system from 2009 to 2014, we identified patients on OACs within 30 days ...

journal_title：Journal of the American Heart Association

authors： Secemsky EA,Butala NM,Kartoun U,Mahmood S,Wasfy JH,Kennedy KF,Shaw SY,Yeh RW

更新日期：2016-10-17 00:00:00

abstract：BACKGROUND:Few studies have examined the impact of lifecourse socioeconomic position (SEP) on cardiovascular disease (CVD) risk among African Americans. METHODS AND RESULTS:We used data from the Jackson Heart Study (JHS) to examine the associations of multiple measures of lifecourse SEP with CVD events in a large coho...

journal_title：Journal of the American Heart Association

authors： Gebreab SY,Diez Roux AV,Brenner AB,Hickson DA,Sims M,Subramanyam M,Griswold ME,Wyatt SB,James SA

更新日期：2015-05-27 00:00:00

abstract：BACKGROUND:Whether the sympathetic nervous system can directly alter central aortic stiffness remains controversial, mainly because of the difficulty in experimentally augmenting peripheral vasoconstrictor activity without changing blood pressure. METHODS AND RESULTS:To address this limitation, we utilized low-level c...

journal_title：Journal of the American Heart Association

authors： Nardone M,Incognito AV,Millar PJ

更新日期：2018-01-29 00:00:00

abstract：:Background Limited data are available on mid-range ejection fraction (mrEF) patients with dilated cardiomyopathy. We sought to define the characteristics, evolution, and long-term prognosis of dilated cardiomyopathy patients with mrEF at diagnosis. Methods and Results We analyzed all dilated cardiomyopathy patients co...

journal_title：Journal of the American Heart Association

authors： Gentile P,Merlo M,Cannatà A,Gobbo M,Artico J,Stolfo D,Gigli M,Ramani F,Barbati G,Pinamonti B,Sinagra G

更新日期：2019-09-03 00:00:00

abstract：:Background Mobile health (mHealth) technologies can deliver interventions to prevent and manage cardiovascular disease (CVD), but mHealth uptake among those with or at risk for CVD remains incompletely explored. Therefore, in this group, we assessed the prevalence of mHealth access and usage, and the association betwe...

journal_title：Journal of the American Heart Association

authors： Shan R,Ding J,Plante TB,Martin SS

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:The intersection of heart failure (HF) and atrial fibrillation (AF) is common, but the burden of AF among black patients with HF is poorly characterized. We sought to determine the prevalence of AF, characteristics, in-hospital outcomes, and warfarin use associated with AF in patients hospitalized with HF as...

journal_title：Journal of the American Heart Association

authors： Thomas KL,Piccini JP,Liang L,Fonarow GC,Yancy CW,Peterson ED,Hernandez AF,Get With the Guidelines Steering Committee and Hospitals.

更新日期：2013-09-26 00:00:00

abstract：:Background Tetrahydrobiopterin is a cofactor of endothelial NO synthase ( eNOS ), which is critical to embryonic heart development. We aimed to study the effects of sapropterin (Kuvan), an orally active synthetic form of tetrahydrobiopterin on eNOS uncoupling and congenital heart defects ( CHD s) induced by pregestati...

journal_title：Journal of the American Heart Association

authors： Engineer A,Saiyin T,Lu X,Kucey AS,Urquhart BL,Drysdale TA,Norozi K,Feng Q

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:Despite guideline recommendations, a significant number of patients with non-ST elevation myocardial infarction (NSTEMI) do not receive dual antiplatelet therapy (DAPT) before angiography "pretreatment." While there may be valid clinical reasons to not pretreat, such as concern for bleeding or multivessel di...

journal_title：Journal of the American Heart Association

authors： Shafiq A,Valle J,Jang JS,Qintar M,Gosch K,Cohen DJ,Singh M,Bach R,Spertus JA

更新日期：2016-06-10 00:00:00

abstract：:Background A previous study reported histologic abnormalities in the pulmonary artery ( PA ) of patients with tetralogy of Fallot ( TOF ). However, the potential effect of these anatomical findings on PA vascular function has not been studied. We hypothesized that TOF patients had abnormal PA vascular function, and th...

journal_title：Journal of the American Heart Association

authors： Egbe AC,Anavekar NS,Connolly HM

更新日期：2019-06-18 00:00:00