Estimating Myocardial Infarction Size With a Simple Electrocardiographic Marker Score.

abstract：BACKGROUND:Decreased arterial elasticity is a risk factor for several cardiovascular outcomes. Longitudinal data on the effect of physical activity in youth on adult arterial elasticity are limited. The aim of this study was to determine the long-term effects of physical activity in children and young adults on carotid...

journal_title：Journal of the American Heart Association

authors： Pälve KS,Pahkala K,Magnussen CG,Koivistoinen T,Juonala M,Kähönen M,Lehtimäki T,Rönnemaa T,Viikari JS,Raitakari OT

更新日期：2014-04-22 00:00:00

abstract：BACKGROUND:Although clinical trials have proved that statin can be used prophylactically against cardiovascular events, the direct effects of statin on plaque development are not well understood. We generated low-density lipoprotein receptor knockout (LDLR(-/-)) pigs to study the effects of early statin administration ...

journal_title：Journal of the American Heart Association

authors： Li Y,Fuchimoto D,Sudo M,Haruta H,Lin QF,Takayama T,Morita S,Nochi T,Suzuki S,Sembon S,Nakai M,Kojima M,Iwamoto M,Hashimoto M,Yoda S,Kunimoto S,Hiro T,Matsumoto T,Mitsumata M,Sugitani M,Saito S,Hirayama A,Onish

更新日期：2016-04-18 00:00:00

abstract：:Background Pharmacists-led medication reviews (MRs) are claimed to be effective for the control of cardiovascular diseases; however, the evidence in the literature is conflicting. The main objective of this meta-analysis was to analyze the impact of pharmacist-led MRs on cardiovascular disease risk factors overall and...

journal_title：Journal of the American Heart Association

authors： Martínez-Mardones F,Fernandez-Llimos F,Benrimoj SI,Ahumada-Canale A,Plaza-Plaza JC,S Tonin F,Garcia-Cardenas V

更新日期：2019-11-19 00:00:00

abstract：:Background Acute type A aortic dissection presents with abrupt onset of pain that requires emergency surgery. However, minimal research exists on posttraumatic stress disorder (PTSD) in survivors. We aimed to quantify the prevalence and describe characteristics of PTSD in patients following dissection. Methods and Res...

journal_title：Journal of the American Heart Association

authors： Pasadyn SR,Roselli EE,Artis AS,Pasadyn CL,Phelan D,Hurley K,Desai MY,Blackstone EH

更新日期：2020-05-05 00:00:00

abstract：:Background Ischemic heart disease continues to be a leading cause of mortality in patients. Extracellular vesicles (EVs) provide a potential for treatment that may induce collateral vessel growth to increase myocardial perfusion. Methods and Results Nineteen male Yorkshire pigs were given a high-fat diet for 4 weeks, ...

journal_title：Journal of the American Heart Association

authors： Scrimgeour LA,Potz BA,Aboul Gheit A,Shi G,Stanley M,Zhang Z,Sodha NR,Ahsan N,Abid MR,Sellke FW

更新日期：2019-08-06 00:00:00

abstract：:Background Higher fibroblast growth factor-23 ( FGF -23) levels are associated with incident heart failure ( HF ) in MESA (the Multiethnic Study of Atherosclerosis). FGF -23 is also associated with left ventricular hypertrophy. Whether the FGF -23 association with HF is similar for heart failure with reduced ejection ...

journal_title：Journal of the American Heart Association

authors： Almahmoud MF,Soliman EZ,Bertoni AG,Kestenbaum B,Katz R,Lima JAC,Ouyang P,Miller PE,Michos ED,Herrington DM

更新日期：2018-09-18 00:00:00

abstract：:See Editorial by Cenko et al. ...

journal_title：Journal of the American Heart Association

authors： Pande AN,Jacobs AK

更新日期：2019-02-19 00:00:00

abstract：:Background The ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial failed to show a reduction in hard clinical end points with an early invasive strategy in stable ischemic heart disease (SIHD). However, the influence of left main disease and high-risk coronary...

journal_title：Journal of the American Heart Association

authors： Bainey KR,Alemayehu W,Welsh RC,Kumar A,King SB 3rd,Kirtane AJ

更新日期：2021-01-05 00:00:00

abstract：:Background Previous studies have reported an association between the timing of menarche and cardiovascular disease ( CVD ). However, emerging studies have not examined the timing of menarche in relation to role of estrogen over a lifetime and major adverse cardiac events ( MACE ). Methods and Results A total of 648 wo...

journal_title：Journal of the American Heart Association

authors： Lee JJ,Cook-Wiens G,Johnson BD,Braunstein GD,Berga SL,Stanczyk FZ,Pepine CJ,Bairey Merz CN,Shufelt CL

更新日期：2019-06-18 00:00:00

abstract：:Background The role of platelets in the development of vascular inflammation and endothelial dysfunction in the pathogenesis of hypertension is well established at this time. Aspirin is known to relieve pain, decrease fever, reduce inflammation, impair platelet aggregation, and prevent clotting, yet its effect in the ...

journal_title：Journal of the American Heart Association

authors： Jiang X,Liu X,Liu X,Wu X,Jose PA,Liu M,Yang Z

更新日期：2020-01-07 00:00:00

abstract：:Background Aging is associated with a modest decline in ankle-brachial index (ABI); however, the underpinnings of this decline are not fully understood. The greater systolic ankle than brachial blood pressure, a normal ABI implies, is partially attributed to lower central than peripheral arterial stiffness. Hence, we ...

journal_title：Journal of the American Heart Association

authors： Oberdier MT,Morrell CH,Lakatta EG,Ferrucci L,AlGhatrif M

更新日期：2019-08-06 00:00:00

abstract：BACKGROUND:The p.Gln554X mutation in desmocollin-2 (DSC2) is prevalent in ≈10% of the Hutterite population. While the homozygous mutation causes severe biventricular arrhythmogenic right ventricular cardiomyopathy, the phenotypic features and prognosis of heterozygotes remain incompletely understood. METHODS AND RESUL...

journal_title：Journal of the American Heart Association

authors： Wong JA,Duff HJ,Yuen T,Kolman L,Exner DV,Weeks SG,Gerull B

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:Besides hypertension, obesity and the metabolic syndrome have recently emerged as risk factors for atrial fibrillation. This study sought to delineate the development of an arrhythmogenic substrate for atrial fibrillation in hypertension with and without concomitant obesity and metabolic syndrome. METHODS A...

journal_title：Journal of the American Heart Association

authors： Hohl M,Lau DH,Müller A,Elliott AD,Linz B,Mahajan R,Hendriks JML,Böhm M,Schotten U,Sanders P,Linz D

更新日期：2017-09-17 00:00:00

abstract：:Background Obesity is a precursor to heart failure with preserved ejection fraction. Biomarkers that identify preclinical metabolic heart disease ( MHD ) in young obese patients would help identify high-risk individuals for heart failure prevention strategies. We assessed the predictive value of GAL3 (galectin-3), FST...

journal_title：Journal of the American Heart Association

authors： Gopal DM,Ayalon N,Wang YC,Siwik D,Sverdlov A,Donohue C,Perez A,Downing J,Apovian C,Silva V,Panagia M,Kolachalama V,Ho JE,Liang CS,Gokce N,Colucci WS

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:Though left ventricular mass (LVM) predicts cardiovascular events (CVD) and mortality in African Americans, limited data exists on factors contributing to change in LVM and its prognostic significance. We hypothesized that baseline blood pressure (BP) and body mass index (BMI) and change in these variables o...

journal_title：Journal of the American Heart Association

authors： Fox ER,Musani SK,Samdarshi TE,Taylor JK,Beard WL,Sarpong DF,Xanthakis V,McClendon EE,Liebson PR,Skelton TN,Butler KR,Mosley TH,Taylor H,Vasan RS

更新日期：2015-02-05 00:00:00

abstract：:Background Application of 18F-sodium fluoride (18F-NaF) positron emission tomography ( PET ) to coronary artery disease has attracted interest. We investigated the utility of 18F-NaF uptake for predicting coronary events and evaluated the combined use of coronary computed tomography (CT) angiography ( CCTA ) and 18F-N...

journal_title：Journal of the American Heart Association

authors： Kitagawa T,Yamamoto H,Nakamoto Y,Sasaki K,Toshimitsu S,Tatsugami F,Awai K,Hirokawa Y,Kihara Y

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:A higher milk consumption may be associated with a lower stroke risk. We conducted a comprehensive systematic review and dose-response meta-analysis of milk and other dairy products in relation to stroke risk. METHODS AND RESULTS:Through a systematic literature search, prospective cohort studies of dairy fo...

journal_title：Journal of the American Heart Association

authors： de Goede J,Soedamah-Muthu SS,Pan A,Gijsbers L,Geleijnse JM

更新日期：2016-05-20 00:00:00

abstract：BACKGROUND:Obesity is causally associated with atherosclerosis, and adipose tissue (AT)-derived exosomes may be implicated in the metabolic complications of obesity. However, the precise role of AT-exosomes in atherogenesis remains unclear. We herein aimed to assess the effect of AT-exosomes on macrophage foam cell for...

journal_title：Journal of the American Heart Association

authors： Xie Z,Wang X,Liu X,Du H,Sun C,Shao X,Tian J,Gu X,Wang H,Tian J,Yu B

更新日期：2018-03-03 00:00:00

abstract：BACKGROUND:Intestinal microbiota have been found to be linked to cardiovascular disease via conversion of the dietary compounds choline and carnitine to the atherogenic metabolite TMAO (trimethylamine-N-oxide). Specifically, a vegan diet was associated with decreased plasma TMAO levels and nearly absent TMAO production...

journal_title：Journal of the American Heart Association

authors： Smits LP,Kootte RS,Levin E,Prodan A,Fuentes S,Zoetendal EG,Wang Z,Levison BS,Cleophas MCP,Kemper EM,Dallinga-Thie GM,Groen AK,Joosten LAB,Netea MG,Stroes ESG,de Vos WM,Hazen SL,Nieuwdorp M

更新日期：2018-03-26 00:00:00

abstract：BACKGROUND:Although several risk factors for acute kidney injury (AKI) have been identified, early detection of AKI in acute decompensated heart failure patients remains a challenge. The aim of this study was to develop and validate a risk score for early prediction of AKI in acute decompensated heart failure patients....

journal_title：Journal of the American Heart Association

authors： Zhou LZ,Yang XB,Guan Y,Xu X,Tan MT,Hou FF,Chen PY

更新日期：2016-11-16 00:00:00

abstract：:The primary goal of the initial ECG evaluation of every wide complex tachycardia is to determine whether the tachyarrhythmia has a ventricular or supraventricular origin. The answer to this question drives immediate patient care decisions, ensuing clinical workup, and long-term management strategies. Thus, the importa...

journal_title：Journal of the American Heart Association

authors： Kashou AH,Noseworthy PA,DeSimone CV,Deshmukh AJ,Asirvatham SJ,May AM

更新日期：2020-06-02 00:00:00

abstract：BACKGROUND:Galectin-3 (Gal-3) participates in different mechanisms involved in atherothrombosis, such as inflammation, proliferation, or macrophage chemotaxis. Thus, there have been committed intensive efforts to elucidate the function of Gal-3 in cardiovascular (CV) diseases. The role of Gal-3 as a circulating biomark...

journal_title：Journal of the American Heart Association

authors： Madrigal-Matute J,Lindholt JS,Fernandez-Garcia CE,Benito-Martin A,Burillo E,Zalba G,Beloqui O,Llamas-Granda P,Ortiz A,Egido J,Blanco-Colio LM,Martin-Ventura JL

更新日期：2014-08-05 00:00:00

abstract：BACKGROUND:Sepsis may adversely affect bleeding risk in anticoagulated patients with atrial fibrillation (AF), but the impact of warfarin treatment in such patients is poorly described. This registry-based nationwide cohort study examined safety of oral anticoagulant treatment (OAC) in patients with preexisting AF who ...

journal_title：Journal of the American Heart Association

authors： Søgaard M,Skjøth F,Kjældgaard JN,Lip GYH,Larsen TB

更新日期：2017-11-09 00:00:00

abstract：BACKGROUND:Early reperfusion in the setting of an ST-elevation myocardial infarction (STEMI) is of utmost importance. However, the effects of early versus late reperfusion in this patient group undergoing primary percutaneous coronary intervention (PCI) have so far been inconsistent in previous studies. The purpose of ...

journal_title：Journal of the American Heart Association

authors： Koul S,Andell P,Martinsson A,Gustav Smith J,van der Pals J,Scherstén F,Jernberg T,Lagerqvist B,Erlinge D

更新日期：2014-03-04 00:00:00

abstract：BACKGROUND:Perioperative antiplatelet agents potentially increase bleeding after non-ST-segment elevation (NSTE) acute coronary syndromes (ACS). The protease-activated receptor 1 antagonist vorapaxar reduced cardiovascular events and was associated with increased bleeding versus placebo in NSTE ACS, but its efficacy an...

journal_title：Journal of the American Heart Association

authors： van Diepen S,Tricoci P,Podder M,Westerhout CM,Aylward PE,Held C,Van de Werf F,Strony J,Wallentin L,Moliterno DJ,White HD,Mahaffey KW,Harrington RA,Armstrong PW

更新日期：2015-12-15 00:00:00

abstract：:Background Some, but not all, studies report associations between shift work and hypertension, suggesting that particular subgroups may be at risk. We examined moderating effects of sleep duration and circadian preference on the relationship between shift work and new blood pressure (BP) medicine use at follow-up. Met...

journal_title：Journal of the American Heart Association

authors： Riegel B,Daus M,Lozano AJ,Malone SK,Patterson F,Hanlon AL

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Accumulated research has shown that the older adult brain is significantly more vulnerable to stroke than the young adult brain. Although recent evidence in young adult rats demonstrates that single-whisker stimulation can result in complete protection from ischemic damage after permanent middle cerebral art...

journal_title：Journal of the American Heart Association

authors： Lay CC,Davis MF,Chen-Bee CH,Frostig RD

更新日期：2012-08-01 00:00:00

abstract：:Background Arterial stiffness is an independent risk factor for cardiovascular disease and can be beneficially influenced by physical activity. However, it is not clear how an individual's physical activity pattern over a week is associated with arterial stiffness. Therefore, we examined the associations of the amount...

journal_title：Journal of the American Heart Association

authors： Vandercappellen EJ,Henry RMA,Savelberg HHCM,van der Berg JD,Reesink KD,Schaper NC,Eussen SJPM,van Dongen MCJM,Dagnelie PC,Schram MT,van Greevenbroek MMJ,Wesselius A,van der Kallen CJH,Köhler S,Stehouwer CDA,Koster A

更新日期：2020-10-20 00:00:00

abstract：:Background Programs targeting the standard modifiable cardiovascular risk factors (SMuRFs: hypertension, diabetes mellitus, hypercholesterolemia, smoking) are critical to tackling coronary heart disease at a community level. However, myocardial infarction in SMuRF-less individuals is not uncommon. This study uses 2 se...

journal_title：Journal of the American Heart Association

authors： Vernon ST,Coffey S,D'Souza M,Chow CK,Kilian J,Hyun K,Shaw JA,Adams M,Roberts-Thomson P,Brieger D,Figtree GA

更新日期：2019-11-05 00:00:00

abstract：BACKGROUND:Healthcare resources vary geographically, but associations between hospital-based resources and acute stroke quality and outcomes remain unclear. METHODS AND RESULTS:Using Get With The Guidelines-Stroke and Dartmouth Atlas of Health Care data, we examined associations between healthcare resource availabilit...

journal_title：Journal of the American Heart Association

authors： O'Brien EC,Wu J,Zhao X,Schulte PJ,Fonarow GC,Hernandez AF,Schwamm LH,Peterson ED,Bhatt DL,Smith EE

更新日期：2017-02-03 00:00:00