Abstract:
:Continuous positive airway pressure (CPAP) is the most efficient treatment of obstructive sleep apnea (OSA). Little is known about the impact of spousal relationship profiles on CPAP adherence. We aimed to identify clusters of couples of OSA patients, and their association with CPAP adherence 120 days after CPAP initiation. In a multicenter prospective study, OSA patients recently prescribed CPAP were enrolled with their spouses. Data about spousal relationships were collected at inclusion and at day 120. Latent class analysis was performed to determine homogeneous groups of spousal relationships. The 290 participants were predominantly males (77%), median age was 53 years and interquartile range (IQR) 46-62, median body mass index (BMI) was 32 kg/m² (IQR: 28.6-35.9) and median apnea-hypopnea index: 43 events per hour (IQR: 33-58). Three couple clusters were identified: 1) older retired couples, 2) young working couples, and 3) mature active couples. Patients in the older retired couples cluster presented the highest CPAP adherence (p < 0.01) independently of initial complaints, OSA severity, and degree of improvement under CPAP. In a large cohort of OSA patients in whom clusters of couples were determined, there was a significant difference in CPAP adherence at day-120 after CPAP initiation.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Mendelson M,Gentina T,Gentina E,Tamisier R,Pépin JL,Bailly Sdoi
10.3390/jcm9061658subject
Has Abstractpub_date
2020-06-01 00:00:00issue
6issn
2077-0383pii
jcm9061658journal_volume
9pub_type
杂志文章abstract::The aim was to perform a translation, cross-cultural adaptation, and psychometric evaluation of the Spanish version of the Tampa Scale of Kinesiophobia for Temporomandibular Disorders (TSK-TMD-S). The study sample included 110 patients with TMD. We translated and cross-culturally adapted the TSK-TMD-S using standard m...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9092831
更新日期:2020-09-01 00:00:00
abstract::Preterm infants are at higher risk for both symmetrical and asymmetrical head molding. This study involved 3D stereophotogrammetry to assess the cranial growth, molding, and incidence of deformational plagiocephaly (DP) in preterm children compared to term born children. Thirty-four preterm infants and 34 term born co...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8101665
更新日期:2019-10-11 00:00:00
abstract::An increasing number of patients with coronary artery disease are at high operative risk due to advanced age, severe comorbidities, complex coronary anatomy, and reduced ejection fraction. Consequently, these high-risk patients are often offered percutaneous coronary intervention (PCI) as an alternative to coronary ar...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9113414
更新日期:2020-10-25 00:00:00
abstract::Stem cells have been the focus of intense research opening up new possibilities for the treatment of various diseases. Mesenchymal stromal cells (MSCs) are multipotent cells with relevant immunomodulatory properties and are thus considered as a promising new strategy for immune disease management. To enhance their eff...
journal_title:Journal of clinical medicine
pub_type: 社论
doi:10.3390/jcm8050626
更新日期:2019-05-08 00:00:00
abstract::Periodontal ligament-derived mesenchymal stem cells (hPDLSCs) possess immunomodulatory abilities which are strongly enhanced by various inflammatory cytokines. Vitamin D3 has anti-inflammatory effects on hPDLSCs and immune cells. However, no study to date has directly compared the influence of 1,25(OH)2D3 on the immun...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8122211
更新日期:2019-12-14 00:00:00
abstract::Traumatic brain injury is not a discrete event but an unfolding sequence of damage to the central nervous system. Not only the acute phase but also the subacute and chronic period after injury, i.e., during inpatient rehabilitation, is characterized by multiple neurotransmitter alterations, cellular dysfunction, and m...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm4091815
更新日期:2015-09-22 00:00:00
abstract::α-Klotho is a known anti-aging protein that exerts diverse physiological effects, including phosphate homeostasis. Klotho expression occurs predominantly in the kidney and is significantly decreased in patients with chronic kidney disease. However, changes in serum klotho levels and impacts of klotho on outcomes among...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9061834
更新日期:2020-06-12 00:00:00
abstract::This study aimed to assess the efficacy of canal filling material removal using three different techniques after filling with a Gutta-Percha (GP) cone and calcium silicate-based sealer, by measuring the percentage of volume debris of GP and sealer remaining intracanal with micro computed tomography (micro-CT). The fil...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8070984
更新日期:2019-07-07 00:00:00
abstract::This phase II randomized controlled trial tested whether intracoronary autologous CD34+ cell therapy could further improve left ventricular (LV) systolic function in patients with diffuse coronary artery disease (CAD) with relatively preserved LV ejection fraction (defined as LVEF >40%) unsuitable for coronary interve...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9041043
更新日期:2020-04-07 00:00:00
abstract::(1) Despite many years of research, melanoma still remains a big challenge for modern medicine. The purpose of this article is to review publicly available clinical trials to find trends regarding the number of trials, their location, and interventions including the most frequently studied drugs and their combinations...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm8030368
更新日期:2019-03-15 00:00:00
abstract::Descriptive and retrospective studies without control groups have suggested a possible association between primary Sjögren's syndrome (pSS) and vitamin B12 (B12) deficiency. This is of importance because several mucosal and neurological features are common to these two conditions and could be prevented or reversed in ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9124063
更新日期:2020-12-16 00:00:00
abstract::The outcome of patients with hepatocellular carcinoma (HCC) is still poor. Decorin is a small leucine-rich proteoglycan, which exerts antiproliferative and antiangiogenic properties in vitro. We aimed to investigate the associations of decorin with physical function and prognosis in patients with HCC. We enrolled 65 p...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9040936
更新日期:2020-03-28 00:00:00
abstract::Multidisciplinary interventions have been developed for patients with atopic dermatitis (AD) and their families, with the aim of improving outcomes such as disease control, adherence, and quality of life. We reviewed the content of different multidisciplinary approaches to intervention for AD and evidence for their im...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm4051156
更新日期:2015-05-21 00:00:00
abstract::We aimed to explore the accuracy of physical examination (PE) to detect the synovial and extra-synovial pathologies in psoriatic arthritis (PsA) in comparison to ultrasonography (US). Twenty-nine PsA patients with hand pain were included in the study. A detailed PE of the hands was performed and US scans were performe...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9092929
更新日期:2020-09-10 00:00:00
abstract::The identification of biomarkers predicting disease severity and outcomes is the focus of intense research in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 infection). Ideally, such biomarkers should be easily derivable from routine tests. We conducted a systematic review and meta-analysis ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10020286
更新日期:2021-01-14 00:00:00
abstract::Proteins have been demonstrated to reduce food intake in animals and humans via peripheral and central mechanisms. Supplementation of a dietetic regimen with single or mixed amino acids might represent an approach to improve the effectiveness of any body weight reduction program in obese subjects. The aim of the prese...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9093054
更新日期:2020-09-22 00:00:00
abstract:INTRODUCTION:Cardiovascular risk factors, pre-existing comorbidities, molecular factors, and the direct effects of second- and third-generation BCR-ABL1 tyrosine kinase inhibitors on the vascular endothelium contribute to the progression of cardiovascular (CV) events, especially atherothrombotic conditions. The study o...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9103269
更新日期:2020-10-12 00:00:00
abstract::To bridge the translational gap between recent discoveries of distinct molecular phenotypes of pancreatic cancer and tangible improvements in patient outcome, there is an urgent need to develop strategies and tools informing and improving the clinical decision process. Radiomics and machine learning approaches can off...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9030724
更新日期:2020-03-07 00:00:00
abstract::This report describes the trends of chorionic villus sampling (CVS) referred for prenatal genetic diagnosis in the past two and a half decades in a Portuguese Center. Our cohort of 491 CVS was mostly performed by the transcervical method at the 12th gestational week. Data collected within the framework of this study r...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm3030838
更新日期:2014-07-24 00:00:00
abstract::The ultrasound (US) pattern of intrathyroidal ectopic thymus (IET) can resemble papillary thyroid carcinoma (PTC) while the extrathyroidal ectopic thymus (EET) can mimic pathological lymph nodes. Recently, the usefulness of strain elastography (SE) was demonstrated in the differential diagnosis, however this method ha...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9123816
更新日期:2020-11-25 00:00:00
abstract::Fetal exposure to particulate matter (PM) is associated with infant developmental delay likely via neuroinflammation and prefrontal cortex lesions; however, whether air-purifier usage, which can reduce indoor PM levels, is related to infant developmental delay remains unknown. We therefore examined the prospective rel...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9061924
更新日期:2020-06-19 00:00:00
abstract:UNLABELLED:The objective of this study was to evaluate the correlation between multiple cardiovascular risk factors (MCRFs) and circulating mononuclear cells (CMCs) in asymptomatic coronary artery disease patients. DESIGN AND METHODS:126 subjects (54 male), aged 48 to 62 years, with asymptomatic coronary artery diseas...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm2030032
更新日期:2013-07-30 00:00:00
abstract::Brain-derived neurotrophic factor (BDNF) facilitates neuronal growth and plasticity, and is crucial for learning and memory. Contactin-1 (CNTN1) is a member of the subfamily of neural immunoglobulin and is involved in the formation of axon connections in the developing nervous system. This cross-sectional study invest...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8091366
更新日期:2019-09-02 00:00:00
abstract:BACKGROUND AND AIM:Although head and/or neck pain attributed to orthostatic hypotension is included in international guidelines, its mechanisms and relevance remain unknown. This study examined the term's relevance and aimed to elucidate the associated clinical features. METHODS:An active stand test was performed to e...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9124125
更新日期:2020-12-21 00:00:00
abstract::Permanent hypoparathyroidism, a feared thyroidectomy complication, leads to significant patient morbidity, medical treatment, and monitoring. This study explores whether preoperative high-dose vitamin D loading decreases the incidence of permanent hypoparathyroidism. In a subgroup analysis, the study examines the pred...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10030442
更新日期:2021-01-24 00:00:00
abstract::Thyroid hormones (THs) exert pleiotropic effects in different mammalian organs, including gonads. Genetic and non-genetic factors, such as ageing and environmental stressors (e.g., low-iodine intake, exposure to endocrine disruptors, etc.), can alter T4/T3 synthesis by the thyroid. In any case, peripheral T3, controll...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9061679
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Cesarean deliveries represent a large percentage of deliveries worldwide. Patients undergoing repeat cesarean deliveries are known to have increased risks for surgical complications. However, little is known regarding potential differences in pain. We sought to compare postoperative opioid consumption and pa...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8122221
更新日期:2019-12-16 00:00:00
abstract:BACKGROUND:We investigated the associations between v-Raf murine sarcoma viral oncogene homolog B1 (BRAFV600E, henceforth BRAF) and v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations and colorectal cancer (CRC) prognosis, using The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GSE39582)...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8010111
更新日期:2019-01-17 00:00:00
abstract:BACKGROUND:Neoadjuvant therapy (NAT) represents a paradigm shift in the management of patients with pancreatic ductal adenocarcinoma (PDAC) with perceived benefits including a higher R0 rate. However, it is unclear whether NAT affects the sites and patterns of recurrence after surgery. This review seeks to compare site...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9072132
更新日期:2020-07-06 00:00:00
abstract::Paraneoplastic neurological syndromes (PNSs) are a heterogeneous group of rare immune-mediated diseases associated with cancer. The aim of this study was to investigate the prevalence of PNSs in the province of Brescia. PNS prevalence was calculated using the Lombardy regional hospital admission records from 1998 to 2...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9103105
更新日期:2020-09-25 00:00:00