当前位置： SCI文献检索 > Journal of Clinical Medicine期刊下所有文献 > Association of Primary Sjögren's Syndrome and Vitamin B12 Deficiency: A Cross-Sectional Case-Control Study.

Association of Primary Sjögren's Syndrome and Vitamin B12 Deficiency: A Cross-Sectional Case-Control Study.

Abstract：

:Descriptive and retrospective studies without control groups have suggested a possible association between primary Sjögren's syndrome (pSS) and vitamin B12 (B12) deficiency. This is of importance because several mucosal and neurological features are common to these two conditions and could be prevented or reversed in case of B12 deficiency. We aimed to evaluate the association between pSS and B12 deficiency. We prospectively assessed the B12 status of 490 patients hospitalized in an internal medicine department over a 15-week period. Patients with pernicious anemia were excluded. We extracted patients with pSS and paired them with controls according to age and sex, with a 1:5 ratio. Twenty-one pSS patients were paired with 105 control patients. The median age was 70 years old (51-75) and 95.2% of patients were women. The plasma B12 level was lower in pSS patients (329 (293-521) ng/L vs. 456 (341-587) ng/L, p < 0.0001). B12 deficiency was associated with pSS (42.9% among pSS patients vs. 11.4% among controls), even after adjustment for other causes of B12 deficiency (OR 6.45 (95%CI: 2.08-20.0)). In conclusion, pSS appeared to be associated with B12 deficiency, even after the exclusion of pernicious anemia. This justifies screening and treating B12 deficiency in pSS patients.

journal_name

J Clin Med

journal_title

Journal of clinical medicine

authors

Urbanski G,Chabrun F,Schaepelynck B,May M,Loiseau M,Schlumberger E,Delattre E,Lavigne C,Lacombe V

doi

10.3390/jcm9124063

subject

Has Abstract

pub_date

2020-12-16 00:00:00

issue

12

issn

2077-0383

pii

jcm9124063

journal_volume

9

pub_type

杂志文章

相关文献

Journal of Clinical Medicine文献大全
  • Hemodynamic Profiles of Cardiogenic Shock Depending on Their Etiology.

    abstract：:The pathophysiology of cardiogenic shock (CS) varies depending on its etiology, which may lead to different hemodynamic profiles (HP) and may help tailor therapy. We aimed to assess the HP of CS patients according to their etiologies of acute myocardial infarction (AMI) and acute decompensated chronic heart failure (A...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9113384

    authors： Gaubert M,Laine M,Resseguier N,Aissaoui N,Puymirat E,Lemesle G,Michelet P,Hraiech S,Lévy B,Delmas C,Bonello L

    更新日期：2020-10-22 00:00:00

  • Gut Microbiota: Implications in Alzheimer's Disease.

    abstract：:Alzheimer's disease (AD), the most common cause of dementia, is a neurodegenerative disease that seriously threatens human health and life quality. The main pathological features of AD include the widespread deposition of amyloid-beta and neurofibrillary tangles in the brain. So far, the pathogenesis of AD remains elu...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9072042

    authors： He Y,Li B,Sun D,Chen S

    更新日期：2020-06-29 00:00:00

  • Analysis of Various Subsets of Circulating Mononuclear Cells in Asymptomatic Coronary Artery Disease.

    abstract：UNLABELLED:The objective of this study was to evaluate the correlation between multiple cardiovascular risk factors (MCRFs) and circulating mononuclear cells (CMCs) in asymptomatic coronary artery disease patients. DESIGN AND METHODS:126 subjects (54 male), aged 48 to 62 years, with asymptomatic coronary artery diseas...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm2030032

    authors： Berezin AE,Kremzer AA

    更新日期：2013-07-30 00:00:00

  • Key Strategies to Optimize Outcomes in Mild-to-Moderate Ulcerative Colitis.

    abstract：:Mesalamine (5-ASA) is the mainstay therapy in patients with mild-to-moderate active ulcerative colitis (UC). However, non-adherence to therapy and practice variability among gastroenterologists represent long-standing barriers, leading to poor outcomes. Additionally, targets to treat in UC are increasingly evolving fr...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9092905

    authors： Solitano V,D'Amico F,Fiorino G,Paridaens K,Peyrin-Biroulet L,Danese S

    更新日期：2020-09-08 00:00:00

  • Fetal and Placental Weight in Pre-Gestational Maternal Obesity (PGMO) vs. Excessive Gestational Weight Gain (EGWG)-A Preliminary Approach to the Perinatal Outcomes in Diet-Controlled Gestational Diabetes Mellitus.

    abstract：:Both pre-gestational maternal obesity (PGMO) and excessive gestational weight gain (EGWG) increase the risk of gestational diabetes mellitus (GDM). Here, we conducted a retrospective study to comparatively examine the relation between fetal birth weight (FW) and placental weight (PW) in PGMO (n = 100) compared to EGWG...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9113530

    authors： Gujski M,Szukiewicz D,Chołuj M,Sawicki W,Bojar I

    更新日期：2020-10-31 00:00:00

  • New Markers of Renal Failure in Multiple Myeloma and Monoclonal Gammopathies.

    abstract：:* Correspondence: kasiajanda@op [...]. ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9061652

    authors： Woziwodzka K,Vesole DH,Małyszko J,Batko K,Jurczyszyn A,Koc-Żórawska E,Krzanowski M,Małyszko J,Żórawski M,Waszczuk-Gajda A,Kuźniewski M,Krzanowska K

    更新日期：2020-05-31 00:00:00

  • Rituximab and Fibrillary Glomerulonephritis: Interest of B Cell Reconstitution Monitoring.

    abstract：:Fibrillary glomerulonephritis (FGN) is a rare glomerular disease characterized by glomerular deposition of randomly arranged non-amyloid fibrils. FGN has a poor renal prognosis and its optimal treatment is a medical challenge. Rituximab therapy has recently emerged as a promising approach even though its mechanism of ...

    journal_title：Journal of clinical medicine

    pub_type：

    doi：10.3390/jcm7110430

    authors： Leibler C,Moktefi A,Matignon M,Debiais-Delpech C,Oniszczuk J,Sahali D,Cohen JL,Grimbert P,Audard V

    更新日期：2018-11-09 00:00:00

  • Image-Based Molecular Phenotyping of Pancreatic Ductal Adenocarcinoma.

    abstract：:To bridge the translational gap between recent discoveries of distinct molecular phenotypes of pancreatic cancer and tangible improvements in patient outcome, there is an urgent need to develop strategies and tools informing and improving the clinical decision process. Radiomics and machine learning approaches can off...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9030724

    authors： Kaissis GA,Ziegelmayer S,Lohöfer FK,Harder FN,Jungmann F,Sasse D,Muckenhuber A,Yen HY,Steiger K,Siveke J,Friess H,Schmid R,Weichert W,Makowski MR,Braren RF

    更新日期：2020-03-07 00:00:00

  • Use of DIAGNOdent and VistaProof in diagnostic of Pre-Cavitated Caries Lesions-A Systematic Review and Meta-Analysis.

    abstract：OBJECTIVE:To analyse the published evidence of the validity of DIAGNDOdent and VistaProof in diagnosing carious depths in pre-cavitated lesions. Material and methods: A systematic review was carried out after identifying a total of 184 articles, including 27 concerning the qualitative review and a subsequent meta-analy...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9010020

    authors： Iranzo-Cortés JE,Montiel-Company JM,Almerich-Torres T,Bellot-Arcís C,Almerich-Silla JM

    更新日期：2019-12-19 00:00:00

  • Treatment of Anaemia in Patients with Acute Burn Injury: A Study of Blood Transfusion Practices.

    abstract：:Objective: To determine blood transfusion practices, risk factors, and outcomes associated with the use of blood products in the setting of the acute management of burn patients at the Victorian Adult Burn Service. Background: Patients with burn injuries have variable transfusion requirements, based on a multitude of ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm10030476

    authors： Tichil I,Rosenblum S,Paul E,Cleland H

    更新日期：2021-01-27 00:00:00

  • Quantitative Analysis of the Seminal Plasma Proteome in Secondary Hypogonadism.

    abstract：:In the grey zone of testosterone levels between 8 and 12 nmol/L, the usefulness of therapy is controversial; as such, markers of tissue action of androgens may be helpful in adjusting clinical decisions. To better understand the effect of the hypothalamic-pituitary-testicular axis on male accessory secretion, we perfo...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8122128

    authors： Grande G,Vincenzoni F,Mancini F,Barrachina F,Giampietro A,Castagnola M,Urbani A,Oliva R,Milardi D,Pontecorvi A

    更新日期：2019-12-03 00:00:00

  • Partial Achilles Tendon Rupture-A Neglected Entity: A Narrative Literature Review on Diagnostics and Treatment Options.

    abstract：:Partial ruptures in the Achilles tendon are rather uncommon and are often misinterpreted as aggravated Achilles tendinopathy, and not always considered as a differential diagnosis. The aim of this literature review was to characterize typical symptoms, to provide an overview of available diagnosis and treatment option...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9103380

    authors： Gatz M,Spang C,Alfredson H

    更新日期：2020-10-21 00:00:00

  • Visual and Topographic Improvement with Epithelium-On, Oxygen-Supplemented, Customized Corneal Cross-Linking for Progressive Keratoconus.

    abstract：:Customized cross-linking has been proposed as an alternative to conventional cross-linking in patients with progressive keratoconus, targeting greater flattening of the cone region and improved visual function. Epithelium-on cross-linking aims to reduce complications associated with epithelial removal, while the addit...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9103222

    authors： Kamiya K,Kanayama S,Takahashi M,Shoji N

    更新日期：2020-10-08 00:00:00

  • Adult Patient Risk Stratification Using a Risk Score for Periodontitis.

    abstract：BACKGROUND:There is a need for analytical tools predicting the risk of periodontitis. The purpose of this study was to estimate and evaluate a risk score for prediction of periodontitis. MATERIALS AND METHODS:This case-cohort study included a random sample of 155 cases (with periodontitis) and 175 controls (randomly s...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8030307

    authors： de Araújo Nobre M,Ferro A,Maló P

    更新日期：2019-03-05 00:00:00

  • Distinct Expression Patterns of VEGFR 1-3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Supporting Clinical Relevance, but not a Prognostic Factor.

    abstract：INTRODUCTION:Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are an increasing tumor entity. Since many patients are diagnosed at an advanced stage, treatment is still challenging and dependent on many tumor and patient specific factors. Therefore, the aim of the present study was to elucidate the expression...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9103368

    authors： Bösch F,Altendorf-Hofmann A,Jacob S,Auernhammer CJ,Spitzweg C,Boeck S,Schubert-Fritschle G,Werner J,Kirchner T,Angele MK,Knösel T

    更新日期：2020-10-21 00:00:00

  • Photodynamic Therapy Using a New Folate Receptor-Targeted Photosensitizer on Peritoneal Ovarian Cancer Cells Induces the Release of Extracellular Vesicles with Immunoactivating Properties.

    abstract：:Often discovered at an advanced stage, ovarian cancer progresses to peritoneal carcinoma, which corresponds to the invasion of the serosa by multiple tumor implants. The current treatment is based on the combination of chemotherapy and tumor cytoreduction surgery. Despite the progress and standardization of surgical t...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9041185

    authors： Baydoun M,Moralès O,Frochot C,Ludovic C,Leroux B,Thecua E,Ziane L,Grabarz A,Kumar A,de Schutter C,Collinet P,Azais H,Mordon S,Delhem N

    更新日期：2020-04-21 00:00:00

  • Low Levels of Low-Density Lipoprotein Cholesterol and Endothelial Function in Subjects without Lipid-Lowering Therapy.

    abstract：:An elevation of serum low-density lipoprotein cholesterol (LDL-C) levels has been associated with endothelial dysfunction in statin naïve subjects. However, there is no information on endothelial function in subjects with extremely low levels of LDL-C. The purpose of the present study was to determine the relationship...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9123796

    authors： Takaeko Y,Kajikawa M,Kishimoto S,Yamaji T,Harada T,Han Y,Kihara Y,Hida E,Chayama K,Goto C,Aibara Y,Yusoff FM,Maruhashi T,Nakashima A,Higashi Y

    更新日期：2020-11-24 00:00:00

  • Systemic Disease and Ocular Comorbidity Analysis of Geographically Isolated Federally Recognized American Indian Tribes of the Intermountain West.

    abstract：BACKGROUND:The American Indian Navajo and Goshute peoples are underserved patient populations residing in the Four Corners area of the United States and Ibupah, Utah, respectively. METHODS:We conducted a cross-sectional study of epidemiological factors and lipid biomarkers that may be associated with type II diabetes,...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9113590

    authors： Hicks PM,Haaland B,Feehan M,Crandall AS,Pettey JH,Nuttall E,Self W,Hartnett ME,Bernstein P,Vitale A,Shakoor A,Shulman JP,Sieminski SF,Kim I,Owen LA,Murtaugh MA,Noyes A,DeAngelis MM

    更新日期：2020-11-07 00:00:00

  • Macular Ganglion Cell Layer Thickness after Macula-Off Rhegmatogenous Retinal Detachment Repair: Scleral Buckling versus Pars Plana Vitrectomy.

    abstract：:(1) Background: We evaluated macular ganglion cell layer-inner plexiform layer (GCL-IPL) thickness in patients with primary macula-off rhegmatogenous retinal detachment (RRD) treated with scleral buckling (SB) or pars plana vitrectomy (PPV) using spectral domain optical coherence tomography (SD-OCT). (2) Methods: In t...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9051411

    authors： Gharbiya M,Albanese GM,Plateroti AM,Marcelli M,Marenco M,Lambiase A

    更新日期：2020-05-10 00:00:00

  • Genes and Variants Underlying Human Congenital Lactic Acidosis-From Genetics to Personalized Treatment.

    abstract：:Congenital lactic acidosis (CLA) is a rare condition in most instances due to a range of inborn errors of metabolism that result in defective mitochondrial function. Even though the implementation of next generation sequencing has been rapid, the diagnosis rate for this highly heterogeneous allelic condition remains l...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8111811

    authors： Bravo-Alonso I,Navarrete R,Vega AI,Ruíz-Sala P,García Silva MT,Martín-Hernández E,Quijada-Fraile P,Belanger-Quintana A,Stanescu S,Bueno M,Vitoria I,Toledo L,Couce ML,García-Jiménez I,Ramos-Ruiz R,Martín MÁ,Desviat LR,Ug

    更新日期：2019-11-01 00:00:00

  • Relationship of Success Rate for Balloon Adhesiolysis with Clinical Outcomes in Chronic Intractable Lumbar Radicular Pain: A Multicenter Prospective Study.

    abstract：:Combined balloon decompression and epidural adhesiolysis has been reported to be effective in refractory lumbar spinal stenosis. Many cases of intractable stenosis have symptom-related multiple target sites for interventional treatment. In this situation it may not be possible to perform balloon adhesiolysis, or even ...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8050606

    authors： Park JY,Ji GY,Lee SW,Park JK,Ha D,Park Y,Cho SS,Moon SH,Shin JW,Kim DJ,Shin DA,Choi SS

    更新日期：2019-05-03 00:00:00

  • Retinoic Acids in the Treatment of Most Lethal Solid Cancers.

    abstract：:Although the use of oral administration of pharmacological all-trans retinoic acid (ATRA) concentration in acute promyelocytic leukaemia (APL) patients was approved for over 20 years and used as standard therapy still to date, the same use in solid cancers is still controversial. In the present review the literature a...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9020360

    authors： Costantini L,Molinari R,Farinon B,Merendino N

    更新日期：2020-01-28 00:00:00

  • N-Glycosylation Alteration of Serum and Salivary Immunoglobulin a Is a Possible Biomarker in Oral Mucositis.

    abstract：BACKGROUND:Oral and enteral mucositis due to high-dose cytostatic treatment administered during autologous and allogeneic stem-cell transplantation increases mortality. Salivary secretory immunoglobulin A (sIgA) is a basic pillar of local immunity in the first line of defense. Altered salivary sialoglycoprotein carbohy...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9061747

    authors： Gebri E,Kovács Z,Mészáros B,Tóth F,Simon Á,Jankovics H,Vonderviszt F,Kiss A,Guttman A,Hortobágyi T

    更新日期：2020-06-05 00:00:00

  • Temporal Trends of Severe Hypoglycemia and Subsequent Mortality in Patients with Advanced Diabetic Kidney Diseases Transitioning to Dialysis.

    abstract：BACKGROUND:Patients with diabetic kidney disease (DKD) are at higher risk of hypoglycemia than diabetic patients without DKD. We aimed to investigate the temporal trends of severe hypoglycemia in advanced DKD patients transitioning to dialysis and examine risk factors associated with severe hypoglycemia. We also invest...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm8040420

    authors： Hsiao CC,Tu HT,Lin CH,Chen KH,Yeh YH,See LC

    更新日期：2019-03-27 00:00:00

  • Background Frequency Patterns in Standard Electroencephalography as an Early Prognostic Tool in Out-of-Hospital Cardiac Arrest Survivors Treated with Targeted Temperature Management.

    abstract：:We investigated the prognostic value of standard electroencephalography, a 30-min recording using 21 electrodes on the scalp, during the early post-cardiac arrest period, and evaluated the performance of electroencephalography findings combined with other clinical features for predicting favourable outcomes in comatos...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm9041113

    authors： Kim YJ,Kim MJ,Koo YS,Kim WY

    更新日期：2020-04-13 00:00:00

  • Clinical Value of CT for Differentiation between Ascites and Hemorrhage: An Experimental In-Vitro Study.

    abstract：BACKGROUND:Abdominal trauma, leading to intra-abdominal bleeding, is a life-threatening condition that might need emergency surgical intervention. Sonography and Computed Tomography (CT) are most commonly used to detect free intra-abdominal fluid. This study investigates the accuracy of CT to distinguish between ascite...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm10010076

    authors： Kerschbaum M,Schurr LA,Riedl M,Mayr A,Weiß I,Klute L,Popp D,Pfeifer C,Ernstberger A,Alt V,Dendl LM

    更新日期：2020-12-28 00:00:00

  • Pharmacotherapy for Irritable Bowel Syndrome.

    abstract：:Irritable bowel syndrome (IBS) is a disorder of the brain-gut axis; the pathophysiological mechanisms include altered colonic motility, bile acid metabolism, neurohormonal regulation, immune dysfunction, alterations in the epithelial barrier and secretory properties of the gut. This article reviews the mechanisms, eff...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm6110101

    authors： Camilleri M,Ford AC

    更新日期：2017-10-27 00:00:00

  • Immunomodulatory Strategies Targeting Dendritic Cells to Improve Corneal Graft Survival.

    abstract：:Even though the cornea is regarded as an immune-privileged tissue, transplantation always comes with the risk of rejection due to mismatches between donor and recipient. It is common sense that an alternative to corticosteroids as the current gold standard for treatment of corneal transplantation is needed. Since bloo...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm9051280

    authors： Schönberg A,Hamdorf M,Bock F

    更新日期：2020-04-28 00:00:00

  • Positive and Negative Affect Changes during Gender-Affirming Hormonal Treatment: Results from the European Network for the Investigation of Gender Incongruence (ENIGI).

    abstract：:Improving transgender people's quality of life (QoL) is the most important goal of gender-affirming care. Prospective changes in affect can influence QoL. We aim to assess the impact of initiating gender-affirming hormonal treatment (HT) on affect. In the European Network for the Investigation of Gender Incongruence (...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章

    doi：10.3390/jcm10020296

    authors： Matthys I,Defreyne J,Elaut E,Fisher AD,Kreukels BPC,Staphorsius A,Den Heijer M,T'Sjoen G

    更新日期：2021-01-14 00:00:00

  • Potential and Challenges of Induced Pluripotent Stem Cells in Liver Diseases Treatment.

    abstract：:Tens of millions of patients are affected by liver disease worldwide. Many of these patients can benefit from cell therapy involving living metabolically active cells, either by treatment of their liver disease, or by prevention of their disease phenotype. Cell therapies, including hepatocyte transplantation and bioar...

    journal_title：Journal of clinical medicine

    pub_type： 杂志文章,评审

    doi：10.3390/jcm3030997

    authors： Yu Y,Wang X,Nyberg SL

    更新日期：2014-09-05 00:00:00