Assessment of the iodine nutritional status among Chinese school-aged children.

abstract：:The goal of this study was to explore the relationship of the BRAFV600E mutation with clinicopathologic factors and evaluate the effect of radioactive iodine (RAI) therapy in a large group of intermediate- and high-risk papillary thyroid cancer (PTC) patients with the BRAFV600E mutation and without distant metastases....

journal_title：Endocrine connections

authors： Zhu G,Deng Y,Pan L,Ouyang W,Feng H,Wu J,Chen P,Wang J,Chen Y,Luo J

更新日期：2019-06-01 00:00:00

abstract：:Acromegaly is a rare and insidious disease characterized by the overproduction of growth hormone (GH) and insulin-like growth factor 1 (IGF1) and is most commonly due to a pituitary adenoma. Patients with acromegaly who experience prolonged exposure to elevated levels of GH and IGF1 have an increased mortality risk an...

journal_title：Endocrine connections

authors： Silverstein JM

更新日期：2015-12-01 00:00:00

abstract：:The genetic aetiology of congenital hypopituitarism (CH) is not entirely elucidated. FGFR1 and PROKR2 loss-of-function mutations are classically involved in hypogonadotrophic hypogonadism (HH), however, due to the clinical and genetic overlap of HH and CH; these genes may also be involved in the pathogenesis of CH. Us...

journal_title：Endocrine connections

authors： Correa FA,Trarbach EB,Tusset C,Latronico AC,Montenegro LR,Carvalho LR,Franca MM,Otto AP,Costalonga EF,Brito VN,Abreu AP,Nishi MY,Jorge AA,Arnhold IJ,Sidis Y,Pitteloud N,Mendonca BB

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:Chromogranin A (CgA) and neuron-specific enolase (NSE) are important markers for neuroendocrine tumors; however, the clinical value of combining these markers has not been well studied. In this study, we investigated the utility of each marker individually and in combination for patients with nonfunctional panc...

journal_title：Endocrine connections

authors： Lv Y,Han X,Zhang C,Fang Y,Pu N,Ji Y,Wang D,Xuefeng X,Lou W

更新日期：2018-01-01 00:00:00

abstract：:According to its incidence patterns, colorectal cancer (CRC) tends to occur more frequently in males than in females, and the evidence shows that CRC is a hormone-related tumor. These findings indicate that androgen receptor (AR) gene methylation might be important for the regulation of the CRC risk in the different s...

journal_title：Endocrine connections

authors： Xia T,Sun H,Huang H,Bi H,Pu R,Zhang L,Zhang Y,Liu Y,Xu J,Onwuka JU,Liu Y,Cui B,Zhao Y

更新日期：2019-07-01 00:00:00

abstract：:Macroprolactinomas are the most common functional pituitary tumours. Hypotheses proposed to explain predominance of large tumours in males are: i) diagnostic delay, as hyperprolactinaemia remains under recognised in males and ii) gender-specific difference in tumour proliferation indices. Our study objectives are to c...

journal_title：Endocrine connections

authors： Khare S,Lila AR,Patt H,Yerawar C,Goroshi M,Bandgar T,Shah NS

更新日期：2016-01-01 00:00:00

abstract：:As many as 20-55% of patients with a history of traumatic brain injury (TBI) experience chronic endocrine dysfunction, leading to impaired quality of life, impaired rehabilitation efforts and lowered life expectancy. Endocrine dysfunction after TBI is thought to result from acceleration-deceleration forces to the brai...

journal_title：Endocrine connections

authors： Rowe RK,Rumney BM,May HG,Permana P,Adelson PD,Harman SM,Lifshitz J,Thomas TC

更新日期：2016-07-01 00:00:00

abstract：:Insufficient insulin release plays a crucial role in the development of unhealthy status in patients with obesity; the present study aimed to classify these patients by the indices for insulin resistance and insulin release. After the indices from OGTT were assessed to achieve high differentiability and low redundancy...

journal_title：Endocrine connections

authors： Li L,Song Q,Yang X

更新日期：2020-02-01 00:00:00

abstract：Background:The effect of isolated maternal hypothyroxinaemia (IMH) on pregnancy complications and neonatal outcomes in human beings is still controversial. Methods:This was a retrospective cohort study based on the electronic medical register system. The records of women with a singleton pregnancy who sought antenatal...

journal_title：Endocrine connections

authors： Su X,Zhao Y,Cao Z,Yang Y,Duan T,Hua J

更新日期：2019-04-01 00:00:00

abstract：:Hypothyroidism is associated with increased risk of atherosclerosis. We assessed carotid intima-media thickness (CIMT), as a marker of atherosclerosis, and endothelial function in patients with hypothyroidism. We included 70 female patients with hypothyroidism in the study, 40 patients with overt and 30 patients with ...

journal_title：Endocrine connections

authors： Saif A,Mousa S,Assem M,Tharwat N,Abdelhamid A

更新日期：2018-10-01 00:00:00

abstract：Objectives:The aims of this paper were to evaluate the levels of Vitamin D (VitD) in patients with heart failure (HF), compared to a control group, to assess the effects of VitD on HF outcome and to compare VitD measurement between LIAISON immunoassay and HPLC-MS-MS methods in this population. Design and Methods:We co...

journal_title：Endocrine connections

authors： Saponaro F,Saba A,Frascarelli S,Frontera C,Clerico A,Scalese M,Sessa MR,Cetani F,Borsari S,Pardi E,Marvelli A,Marcocci C,Passino C,Zucchi R

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:Metyrapone has been approved for the treatment of patients with Cushing's syndrome (CS), but only few retrospective clinical studies are available. The aim of our study was the prospective assessment of metyrapone as pre-operative treatment. DESIGN AND METHODS:Before adrenalectomy, 7 patients with ACTH-indep...

journal_title：Endocrine connections

authors： Puglisi S,Perotti P,Barbot M,Cosio P,Scaroni C,Stigliano A,Lardo P,Morelli V,Polledri E,Chiodini I,Reimondo G,Pia A,Terzolo M

更新日期：2018-09-01 00:00:00

abstract：:Phaeochromocytomas and paragangliomas (PPGLs) are tumours of the adrenal medulla and extra-adrenal sympathetic nervous system which often secrete catecholamines. Variants of the SDHX (SDHA, -AF2, -B, -C, -D) genes are a frequent cause of familial PPGLs. In this study from a single tertiary centre, we aimed to characte...

journal_title：Endocrine connections

authors： Main AM,Rossing M,Borgwardt L,Grønkær Toft B,Rasmussen ÅK,Feldt-Rasmussen U

更新日期：2020-08-01 00:00:00

abstract：:This study aims to summarize and analyze the clinical manifestations, genetic characteristics, treatment modalities and long-term prognosis of congenital hyperinsulinemia (CHI) in Chinese children. Sixty children with CHI, who were treated at Beijing Children's Hospital from January 2014 to August 2017, and their fami...

journal_title：Endocrine connections

authors： Xu ZD,Zhang W,Liu M,Wang HM,Hui PP,Liang XJ,Yan J,Wu YJ,Sang YM,Zhu C,Ni GC

更新日期：2018-11-12 00:00:00

abstract：AIMS:Gestational diabetes mellitus (GDM)-induced macrosomia is predominantly characterized by fat accumulation, which is closely related to adipocyte differentiation. An unknown long noncoding RNA RP11-290L1.3, referred to as RP11, was identified to be dramatically upregulated in the umbilical cord blood of women with ...

journal_title：Endocrine connections

authors： Lin Y,Zhang Y,Xu L,Long W,Shan C,Ding H,You L,Zhao C,Shi Z

更新日期：2021-01-01 00:00:00

abstract：:Failure to suppress testosterone below 0.7 nM in castrated prostate cancer patients is associated with poor clinical outcomes. Testosterone levels in castrated patients are therefore routinely measured. Although mass spectrometry is the gold standard used to measure testosterone, most hospitals use an immunoassay meth...

journal_title：Endocrine connections

authors： Rouleau M,Lemire F,Déry M,Thériault B,Dubois G,Fradet Y,Toren P,Guillemette C,Lacombe L,Klotz L,Saad F,Guérette D,Pouliot F

更新日期：2019-02-01 00:00:00

abstract：:Growth hormone (GH) is used to treat short stature and growth failure associated with growth disorders. Birth size and GH status variably modulate response to GH therapy. The aim of this study was to determine the effect of birth size on response to GH therapy, and to determine the impact of GH status in patients born...

journal_title：Endocrine connections

authors： Rapaport R,Lee P,Ross J,Saenger P,Ostrow V,Piccoli G

更新日期：2018-08-23 00:00:00

abstract：:Few data are available on the association between serum lipids and insulin secretion (ISEC) in children. We evaluated the association of triglycerides (TG), HDL cholesterol (HDL-C) and LDL cholesterol (LDL-C) with ISEC in 1150 non-diabetic obese children and adolescents using multivariable robust median regression. Th...

journal_title：Endocrine connections

authors： Bedogni G,Mari A,De Col A,Tamini S,Gastaldelli A,Sartorio A

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively studied. Cardiac magnetic resonance imaging (CMR) contrast enhancement and novel sensitive T1 mapping to...

journal_title：Endocrine connections

authors： Grytaas MA,Sellevåg K,Thordarson HB,Husebye ES,Løvås K,Larsen TH

更新日期：2018-03-01 00:00:00

abstract：:Many biomarkers are associated with type 2 diabetes (T2D) risk in epidemiological observations. The aim of this study was to identify and summarize current evidence for causal effects of biomarkers on T2D. A systematic literature search in PubMed and EMBASE (until April 2015) was done to identify Mendelian randomizati...

journal_title：Endocrine connections

authors： Abbasi A

更新日期：2015-12-01 00:00:00

abstract：Purpose:Gallbladder neuroendocrine neoplasm (GB-NEN) is a relatively rare neoplasm, accounting for 0.5% of all neuroendocrine neoplasm cases and 2.1% of gallbladder cancers. Because of the limited understanding of GB-NEN, the aim of this study was to explore the clinicopathology and survival of GB-NEN patients selected...

journal_title：Endocrine connections

authors： Cen D,Liu H,Wan Z,Lin Z,Wang Y,Xu J,Liang Y

更新日期：2019-09-01 00:00:00

abstract：:Estradiol has been used to prevent metabolic diseases, bone loss and menopausal symptoms, even though it might raise the risk of cancer. Metformin is usually prescribed for type 2 diabetes mellitus and lowers food intake and body mass while improving insulin resistance and the lipid profile. Ovariectomized rats show i...

journal_title：Endocrine connections

authors： Barthem CS,Rossetti CL,Carvalho DP,da-Silva WS

更新日期：2019-12-01 00:00:00

abstract：Objectives:Walking and postural balance are extremely important to obtain food and to work. Both are critical for quality of life and ability to survive. While walking reflects musculoskeletal and cardiopulmonary systems, postural balance depends on body size, muscle tone, visual, vestibular and nervous systems. Since ...

journal_title：Endocrine connections

authors： Santana-Ribeiro AA,Moreira-Brasileiro GA,Aguiar-Oliveira MH,Salvatori R,Carvalho VO,Alvim-Pereira CK,Araújo-Daniel CR,Reis-Costa JG,Andrade-Guimarães AL,Oliveira-Santos AA,Vieira ER,Gois-Junior MB

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Little is known about how women with isolated GnRH deficiency cope with their condition. This study aimed to examine the health and informational needs of women with congenital hypogonadotropic hypogonadism (CHH) and evaluate if their experiences differ from women with more common forms of infertility. DESIG...

journal_title：Endocrine connections

authors： Dzemaili S,Tiemensma J,Quinton R,Pitteloud N,Morin D,Dwyer AA

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Worldwide there is a high prevalence of 25-hydroxyvitamin D (25OHD) deficiency and has been associated with adverse outcomes during pregnancy. OBJECTIVE:This is a nested, case-control study in a longitudinal cohort to compare the serum 25OHD levels and other biomarkers throughout pregnancy in a group of 20 ...

journal_title：Endocrine connections

authors： Agudelo-Zapata Y,Maldonado-Acosta LM,Sandoval-Alzate HF,Poveda NE,Garcés MF,Cortés-Vásquez JA,Linares-Vaca AF,Mancera-Rodríguez CA,Perea-Ariza SA,Ramírez-Iriarte KY,Castro-Saldarriaga CA,Arteaga-Diaz JM,Franco-Vega R,Ángel-Müll

更新日期：2018-05-01 00:00:00

abstract：:Background and objectives Glucocorticoids are used to manage adrenal insufficiency (AI). We describe treatments used in the United Kingdom and real-world clinical outcomes for each treatment. Methods We used 2010-2016 primary care data from The Health Improvement Network (THIN). Descriptive analyses were conducted, an...

journal_title：Endocrine connections

authors： Iqbal K,Halsby K,Murray RD,Carroll PV,Petermann R

更新日期：2019-01-01 00:00:00

abstract：:This study aimed to evaluate the evolving trends in clinicopathological features of pancreatic neuroendocrine tumors and to analyze the predictors of recurrence after curative resection. Data collected retrospectively from a single center between January 1990 and December 2017 were analyzed. Patients were categorized ...

journal_title：Endocrine connections

authors： Kim H,Song KB,Hwang DW,Lee JH,Alshammary S,Kim SC

更新日期：2019-07-01 00:00:00

abstract：Aims:Neprilysin degrades natriuretic peptides in circulation and is also suggested to degrade the gut hormones gastrin and cholecystokinin. Neprilysin inhibition has become a therapeutic strategy and thus a regimen in need of further testing in terms of other hormonal axes besides natriuretic peptides. The aim of this ...

journal_title：Endocrine connections

authors： Andersen UØ,Terzic D,Wewer Albrechtsen NJ,Dall Mark P,Plomgaard P,Rehfeld JF,Gustafsson F,Goetze JP

更新日期：2020-05-01 00:00:00

abstract：CONTEXT:The aim of this study was to assess the plasma leptin, adiponectin, resistin, visfatin/NAMPT, omentin-1, vaspin, apelin, TNF-α, IL-6 and RBP4 levels in relation to hormonal changes during the menstrual cycle in young, healthy, normal-weight women. METHODS:The study involved 52 young, healthy, normal-weight wom...

journal_title：Endocrine connections

authors： Wyskida K,Franik G,Wikarek T,Owczarek A,Delroba A,Chudek J,Sikora J,Olszanecka-Glinianowicz M

更新日期：2017-11-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is known to be associated with insulin resistance, atherosclerosis, and low serum IGF1 levels. We have described a large cohort of patients with isolated GH deficiency (IGHD) due to the c.57+1G→A mutation in the GHRH receptor gene. These subjects have increased insulin sensitiv...

journal_title：Endocrine connections

authors： Diniz RD,Souza RM,Salvatori R,Franca A,Gomes-Santos E,Ferrão TO,Oliveira CR,Santana JA,Pereira FA,Barbosa RA,Souza AH,Pereira RM,Oliveira-Santos AA,Silva AM,Santana-Júnior FJ,Valença EH,Campos VC,Aguiar-Oliveira MH

更新日期：2014-09-01 00:00:00