Androgen receptor gene methylation related to colorectal cancer risk.

abstract：Objective:Accurate measurement of steroid hormones remains challenging. Mass spectrometry affords a reliable means for quantitating steroid profiles accurately. Our objective was to establish and define (1) the extent of diurnal fluctuations in steroid concentrations that potentially necessitate strict adherence to tim...

journal_title：Endocrine connections

authors： Parikh TP,Stolze B,Ozarda Y,Jonklaas J,Welsh K,Masika L,Hill M,DeCherney A,Soldin SJ

更新日期：2018-12-01 00:00:00

abstract：:The experience in the field of islet transplantation shows that it is possible to replace β cells in a patient with type 1 diabetes (T1D), but this cell therapy is limited by the scarcity of organ donors and by the danger associated to the immunosuppressive drugs. Stem cell therapy is becoming a concrete opportunity t...

journal_title：Endocrine connections

authors： Cito M,Pellegrini S,Piemonti L,Sordi V

更新日期：2018-03-01 00:00:00

abstract：:The goal of this study was to explore the relationship of the BRAFV600E mutation with clinicopathologic factors and evaluate the effect of radioactive iodine (RAI) therapy in a large group of intermediate- and high-risk papillary thyroid cancer (PTC) patients with the BRAFV600E mutation and without distant metastases....

journal_title：Endocrine connections

authors： Zhu G,Deng Y,Pan L,Ouyang W,Feng H,Wu J,Chen P,Wang J,Chen Y,Luo J

更新日期：2019-06-01 00:00:00

abstract：:Chemerin is a recently discovered adipokine with inflammatory and metabolic actions relevant for chronic disease development. However, evidence from human research on the role of chemerin in chronic disease risk is still lacking. We assessed the reliability of plasma chemerin concentrations measured on two occasions o...

journal_title：Endocrine connections

authors： Eichelmann F,Weikert C,di Giuseppe R,Biemann R,Isermann B,Schulze MB,Boeing H,Aleksandrova K

更新日期：2017-07-01 00:00:00

abstract：AIMS:The cumulative effect of gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy (HDP) on postpartum cardio-metabolic diseases is equivocal. We aimed to assess the associations of GDM and HDP's individual and synergic contribution to risks of postpartum cardio-metabolic diseases (metabolic synd...

journal_title：Endocrine connections

authors： Li LJ,Aris IM,Su LL,Chong YS,Wong TY,Tan KH,Wang JJ

更新日期：2018-03-01 00:00:00

abstract：:The vasoactive intestinal peptide receptor 2 (VPAC2) is widely distributed throughout the body and is also overexpressed in a variety of human neoplastic tissues. However, little is known about its precise tissue distribution, regulation and function, which is in part be due to the lack of specific monoclonal anti-VPA...

journal_title：Endocrine connections

authors： Schulz S,Mann A,Novakhov B,Piggins HD,Lupp A

更新日期：2015-03-01 00:00:00

abstract：:To date, the value of fasting plasma acylated ghrelin (AG) and unacylated ghrelin (UAG) as potential novel biomarkers in patients with neuroendocrine tumors (NETs) is unknown. The aims of this study are to (i) compare fasting AG and UAG levels between nonobese, nondiabetic NET patients (N=28) and age- (±3 years) and s...

journal_title：Endocrine connections

authors： van Adrichem RC,van der Lely AJ,Huisman M,Kramer P,Feelders RA,Delhanty PJ,de Herder WW

更新日期：2016-07-01 00:00:00

abstract：:Classic galactosemia is a rare inborn error of galactose metabolism with a birth prevalence of about 1/30 000-60 000. Long-term complications occurring despite dietary treatment consist of premature ovarian insufficiency (POI) and neurodevelopmental impairments. We performed with the French Reference Centers for Rare ...

journal_title：Endocrine connections

authors： Flechtner I,Viaud M,Kariyawasam D,Perrissin-Fabert M,Bidet M,Bachelot A,Touraine P,Labrune P,De Lonlay P,Polak M,Galactosemia Study Group GSG

更新日期：2021-01-01 00:00:00

abstract：Objectives:The aims of this paper were to evaluate the levels of Vitamin D (VitD) in patients with heart failure (HF), compared to a control group, to assess the effects of VitD on HF outcome and to compare VitD measurement between LIAISON immunoassay and HPLC-MS-MS methods in this population. Design and Methods:We co...

journal_title：Endocrine connections

authors： Saponaro F,Saba A,Frascarelli S,Frontera C,Clerico A,Scalese M,Sessa MR,Cetani F,Borsari S,Pardi E,Marvelli A,Marcocci C,Passino C,Zucchi R

更新日期：2018-09-01 00:00:00

abstract：AIMS:Gestational diabetes mellitus (GDM)-induced macrosomia is predominantly characterized by fat accumulation, which is closely related to adipocyte differentiation. An unknown long noncoding RNA RP11-290L1.3, referred to as RP11, was identified to be dramatically upregulated in the umbilical cord blood of women with ...

journal_title：Endocrine connections

authors： Lin Y,Zhang Y,Xu L,Long W,Shan C,Ding H,You L,Zhao C,Shi Z

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Patients with acromegaly can be treated with surgery, medical therapy and/or radiation therapy. For the patients not being cured with surgery, treatment with somatostatin analogues (SSAs) is the primary therapy. SSA can be taken by self- or partner-administered injections in addition to being given by a nu...

journal_title：Endocrine connections

authors： Follin C,Karlsson S

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:Little is known about how women with isolated GnRH deficiency cope with their condition. This study aimed to examine the health and informational needs of women with congenital hypogonadotropic hypogonadism (CHH) and evaluate if their experiences differ from women with more common forms of infertility. DESIG...

journal_title：Endocrine connections

authors： Dzemaili S,Tiemensma J,Quinton R,Pitteloud N,Morin D,Dwyer AA

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION AND AIM:Ectopic ACTH secretion (EAS) is mostly secondary to thoracic/abdominal neuroendocrine tumours (NETs), or small cell-lung carcinoma (SCLC). We studied the diagnostic accuracy of computed tomography (CT) with 68Ga-Dota derivatives (68Ga-SSTR) positron emission tomography (PET) in localizing ACTH-secr...

journal_title：Endocrine connections

authors： Ceccato F,Cecchin D,Gregianin M,Ricci G,Campi C,Crimì F,Bergamo M,Versari A,Lacognata C,Rea F,Barbot M,Scaroni C

更新日期：2020-03-01 00:00:00

abstract：:The aim of this study was to test i) whether patients having diabetes and ischemic heart disease (IHD), i.e., patients suffering from two chronic diseases, demonstrate a higher degree of chronic stress when compared with patients suffering from IHD alone, and ii) whether suffering from the two chronic diseases results...

journal_title：Endocrine connections

authors： Bergmann N,Ballegaard S,Holmager P,Bech P,Hjalmarson A,Gyntelberg F,Faber J

更新日期：2014-12-01 00:00:00

abstract：:Thyroid hormones stimulate bone turnover in adults by increasing osteoclastic bone resorption. TSH suppressive therapy is usually applied in patients with differentiated thyroid cancer (DTC) to improve the disease outcome. Over the last decades several authors have closely monitored the potential harm suffered by the ...

journal_title：Endocrine connections

authors： Brancatella A,Marcocci C

更新日期：2020-07-01 00:00:00

abstract：:This study aims to summarize and analyze the clinical manifestations, genetic characteristics, treatment modalities and long-term prognosis of congenital hyperinsulinemia (CHI) in Chinese children. Sixty children with CHI, who were treated at Beijing Children's Hospital from January 2014 to August 2017, and their fami...

journal_title：Endocrine connections

authors： Xu ZD,Zhang W,Liu M,Wang HM,Hui PP,Liang XJ,Yan J,Wu YJ,Sang YM,Zhu C,Ni GC

更新日期：2018-11-12 00:00:00

abstract：OBJECTIVE:Metyrapone has been approved for the treatment of patients with Cushing's syndrome (CS), but only few retrospective clinical studies are available. The aim of our study was the prospective assessment of metyrapone as pre-operative treatment. DESIGN AND METHODS:Before adrenalectomy, 7 patients with ACTH-indep...

journal_title：Endocrine connections

authors： Puglisi S,Perotti P,Barbot M,Cosio P,Scaroni C,Stigliano A,Lardo P,Morelli V,Polledri E,Chiodini I,Reimondo G,Pia A,Terzolo M

更新日期：2018-09-01 00:00:00

abstract：:Few data are available on the association between serum lipids and insulin secretion (ISEC) in children. We evaluated the association of triglycerides (TG), HDL cholesterol (HDL-C) and LDL cholesterol (LDL-C) with ISEC in 1150 non-diabetic obese children and adolescents using multivariable robust median regression. Th...

journal_title：Endocrine connections

authors： Bedogni G,Mari A,De Col A,Tamini S,Gastaldelli A,Sartorio A

更新日期：2019-10-01 00:00:00

abstract：:Insufficient insulin release plays a crucial role in the development of unhealthy status in patients with obesity; the present study aimed to classify these patients by the indices for insulin resistance and insulin release. After the indices from OGTT were assessed to achieve high differentiability and low redundancy...

journal_title：Endocrine connections

authors： Li L,Song Q,Yang X

更新日期：2020-02-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is known to be associated with insulin resistance, atherosclerosis, and low serum IGF1 levels. We have described a large cohort of patients with isolated GH deficiency (IGHD) due to the c.57+1G→A mutation in the GHRH receptor gene. These subjects have increased insulin sensitiv...

journal_title：Endocrine connections

authors： Diniz RD,Souza RM,Salvatori R,Franca A,Gomes-Santos E,Ferrão TO,Oliveira CR,Santana JA,Pereira FA,Barbosa RA,Souza AH,Pereira RM,Oliveira-Santos AA,Silva AM,Santana-Júnior FJ,Valença EH,Campos VC,Aguiar-Oliveira MH

更新日期：2014-09-01 00:00:00

abstract：:B lymphocytes are the source of autoantibodies against the thyroid-stimulating hormone receptor (TSHR) in Graves' disease (GD). Characterization of autoimmune B-cell expression profiles might enable a better understanding of GD pathogenesis. To reveal this, the expression levels of long noncoding RNAs (lncRNAs) and mR...

journal_title：Endocrine connections

authors： Jiang X,Wang Y,Li X,He L,Yang Q,Wang W,Liu J,Zha B

更新日期：2020-05-01 00:00:00

abstract：:Failure to suppress testosterone below 0.7 nM in castrated prostate cancer patients is associated with poor clinical outcomes. Testosterone levels in castrated patients are therefore routinely measured. Although mass spectrometry is the gold standard used to measure testosterone, most hospitals use an immunoassay meth...

journal_title：Endocrine connections

authors： Rouleau M,Lemire F,Déry M,Thériault B,Dubois G,Fradet Y,Toren P,Guillemette C,Lacombe L,Klotz L,Saad F,Guérette D,Pouliot F

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:The Institute of Medicine 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D specified higher intakes for all age groups compared to the 1997 report, but also cautioned against spurious claims about an epidemic of vitamin D deficiency and against advocates of higher intake requirements. Over ...

journal_title：Endocrine connections

authors： McKenna MJ,Murray BF,O'Keane M,Kilbane MT

更新日期：2015-09-01 00:00:00

abstract：:Acromegaly is a rare and insidious disease characterized by the overproduction of growth hormone (GH) and insulin-like growth factor 1 (IGF1) and is most commonly due to a pituitary adenoma. Patients with acromegaly who experience prolonged exposure to elevated levels of GH and IGF1 have an increased mortality risk an...

journal_title：Endocrine connections

authors： Silverstein JM

更新日期：2015-12-01 00:00:00

abstract：Aims:Neprilysin degrades natriuretic peptides in circulation and is also suggested to degrade the gut hormones gastrin and cholecystokinin. Neprilysin inhibition has become a therapeutic strategy and thus a regimen in need of further testing in terms of other hormonal axes besides natriuretic peptides. The aim of this ...

journal_title：Endocrine connections

authors： Andersen UØ,Terzic D,Wewer Albrechtsen NJ,Dall Mark P,Plomgaard P,Rehfeld JF,Gustafsson F,Goetze JP

更新日期：2020-05-01 00:00:00

abstract：:The rapid increase of obesity during the last decades and its future prospects are alarming. Besides the general discussed causes of obesity, the 'Developmental Origins of Health and Disease' (DOHaD) hypothesis received more attention in recent years. This hypothesis postulates an adverse influence during early develo...

journal_title：Endocrine connections

authors： Ernst J,Gert K,Kraus FB,Rolle-Kampczyk UE,Wabitsch M,Dehghani F,Schaedlich K

更新日期：2020-07-01 00:00:00

abstract：:N/A. ...

journal_title：Endocrine connections

authors： Koehrle J

更新日期：2021-01-01 00:00:00

abstract：:Tumor cells require large amounts of energy to sustain growth. Through the mediated transport of glucose transporters, the uptake and utilization of glucose by tumor cells are significantly enhanced in the hypoxic microenvironment. Pituitary adenomas are benign tumors with high-energy metabolisms. We aimed to investig...

journal_title：Endocrine connections

authors： Mei T,Zhang J,Wei L,Qi X,Ma Y,Liu X,Chen S,Li S,Wu J,Wang S

更新日期：2018-12-01 00:00:00

abstract：:Sex development is a process under genetic control directing both the bi-potential gonads to become either a testis or an ovary, and the consequent differentiation of internal ducts and external genitalia. This complex series of events can be altered by a large number of genetic and non-genetic factors. Disorders of s...

journal_title：Endocrine connections

authors： Laino L,Majore S,Preziosi N,Grammatico B,De Bernardo C,Scommegna S,Rapone AM,Marrocco G,Bottillo I,Grammatico P

更新日期：2014-12-01 00:00:00

abstract：:Hormonal changes during pregnancy can trigger gestational diabetes (GDM), which is constantly increasing. Its main characteristic is pronounced insulin resistance, but it appears to be a multifactorial process involving several metabolic factors; taken together, the latter leads to silent or clinically evident cardiov...

journal_title：Endocrine connections

authors： Patti AM,Pafili K,Papanas N,Rizzo M

更新日期：2018-05-01 00:00:00