The role of 68Ga-DOTA derivatives PET-CT in patients with ectopic ACTH syndrome.

abstract：:The role of G protein-coupled estrogen receptor 1 (GPER) signaling, including promotion of Ezrin phosphorylation (which could be activated by estrogen), has not yet been clearly identified in triple-negative breast cancer (TNBC). This study aimed to evaluate the prognostic value of GPER and Ezrin in TNBC patients. Cli...

journal_title：Endocrine connections

authors： Ye S,Xu Y,Li J,Zheng S,Sun P,Wang T

更新日期：2019-06-01 00:00:00

abstract：Objective:First-line chemotherapy in metastatic neuroendocrine carcinomas (NECs) is based on etoposide and platinum. However, there is no standard concerning second-line treatment. The objective of this study was to evaluate efficacy and tolerance of dacarbazine or temozolomide in metastatic digestive NEC as post first...

journal_title：Endocrine connections

authors： Couronne T,Girot P,Hadoux J,Lecomte T,Durand A,Fine C,Vandevoorde K,Lombard-Bohas C,Walter T

更新日期：2020-06-01 00:00:00

abstract：:Tumor cells require large amounts of energy to sustain growth. Through the mediated transport of glucose transporters, the uptake and utilization of glucose by tumor cells are significantly enhanced in the hypoxic microenvironment. Pituitary adenomas are benign tumors with high-energy metabolisms. We aimed to investig...

journal_title：Endocrine connections

authors： Mei T,Zhang J,Wei L,Qi X,Ma Y,Liu X,Chen S,Li S,Wu J,Wang S

更新日期：2018-12-01 00:00:00

abstract：:Islet transplantation is currently the only minimally invasive therapy available for patients with type 1 diabetes that can lead to insulin independence; however, it is limited to only a small number of patients. Although clinical procedures have improved in the isolation and culture of islets, a large number of islet...

journal_title：Endocrine connections

authors： Rojas-Canales DM,Waibel M,Forget A,Penko D,Nitschke J,Harding FJ,Delalat B,Blencowe A,Loudovaris T,Grey ST,Thomas HE,Kay TWH,Drogemuller CJ,Voelcker NH,Coates PT

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Chromogranin A (CgA) and neuron-specific enolase (NSE) are important markers for neuroendocrine tumors; however, the clinical value of combining these markers has not been well studied. In this study, we investigated the utility of each marker individually and in combination for patients with nonfunctional panc...

journal_title：Endocrine connections

authors： Lv Y,Han X,Zhang C,Fang Y,Pu N,Ji Y,Wang D,Xuefeng X,Lou W

更新日期：2018-01-01 00:00:00

abstract：:The experience in the field of islet transplantation shows that it is possible to replace β cells in a patient with type 1 diabetes (T1D), but this cell therapy is limited by the scarcity of organ donors and by the danger associated to the immunosuppressive drugs. Stem cell therapy is becoming a concrete opportunity t...

journal_title：Endocrine connections

authors： Cito M,Pellegrini S,Piemonti L,Sordi V

更新日期：2018-03-01 00:00:00

abstract：:Hypothyroidism is associated with increased risk of atherosclerosis. We assessed carotid intima-media thickness (CIMT), as a marker of atherosclerosis, and endothelial function in patients with hypothyroidism. We included 70 female patients with hypothyroidism in the study, 40 patients with overt and 30 patients with ...

journal_title：Endocrine connections

authors： Saif A,Mousa S,Assem M,Tharwat N,Abdelhamid A

更新日期：2018-10-01 00:00:00

abstract：:Hypercalcemic crisis is a severe but rare complication of primary hyperparathyroidism (PHPT), and data on denosumab treatment of patients with this disease is still very limited. The aim of this paper is to investigate the hypocalcemic effect of denosumab in PHPT patients with severe hypercalcemia when surgery should ...

journal_title：Endocrine connections

authors： Eremkina A,Krupinova J,Dobreva E,Gorbacheva A,Bibik E,Samsonova M,Ajnetdinova A,Mokrysheva N

更新日期：2020-10-01 00:00:00

abstract：CONTEXT:The aim of this study was to assess the plasma leptin, adiponectin, resistin, visfatin/NAMPT, omentin-1, vaspin, apelin, TNF-α, IL-6 and RBP4 levels in relation to hormonal changes during the menstrual cycle in young, healthy, normal-weight women. METHODS:The study involved 52 young, healthy, normal-weight wom...

journal_title：Endocrine connections

authors： Wyskida K,Franik G,Wikarek T,Owczarek A,Delroba A,Chudek J,Sikora J,Olszanecka-Glinianowicz M

更新日期：2017-11-01 00:00:00

abstract：Background:The effect of isolated maternal hypothyroxinaemia (IMH) on pregnancy complications and neonatal outcomes in human beings is still controversial. Methods:This was a retrospective cohort study based on the electronic medical register system. The records of women with a singleton pregnancy who sought antenatal...

journal_title：Endocrine connections

authors： Su X,Zhao Y,Cao Z,Yang Y,Duan T,Hua J

更新日期：2019-04-01 00:00:00

abstract：:This study aimed to evaluate the evolving trends in clinicopathological features of pancreatic neuroendocrine tumors and to analyze the predictors of recurrence after curative resection. Data collected retrospectively from a single center between January 1990 and December 2017 were analyzed. Patients were categorized ...

journal_title：Endocrine connections

authors： Kim H,Song KB,Hwang DW,Lee JH,Alshammary S,Kim SC

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Worldwide there is a high prevalence of 25-hydroxyvitamin D (25OHD) deficiency and has been associated with adverse outcomes during pregnancy. OBJECTIVE:This is a nested, case-control study in a longitudinal cohort to compare the serum 25OHD levels and other biomarkers throughout pregnancy in a group of 20 ...

journal_title：Endocrine connections

authors： Agudelo-Zapata Y,Maldonado-Acosta LM,Sandoval-Alzate HF,Poveda NE,Garcés MF,Cortés-Vásquez JA,Linares-Vaca AF,Mancera-Rodríguez CA,Perea-Ariza SA,Ramírez-Iriarte KY,Castro-Saldarriaga CA,Arteaga-Diaz JM,Franco-Vega R,Ángel-Müll

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Patients with non-functioning pituitary adenomas exhibit high morbidity and mortality rates. Growth hormone deficiency and high doses of glucocorticoid substitution therapy have been identified as corresponding risk factors. Interestingly, high levels of endogenous cortisol in, e.g., patients with post-trauma...

journal_title：Endocrine connections

authors： Athanasoulia-Kaspar AP,Auer MK,Stalla GK,Jakovcevski M

更新日期：2018-08-01 00:00:00

abstract：:Few data are available on the association between serum lipids and insulin secretion (ISEC) in children. We evaluated the association of triglycerides (TG), HDL cholesterol (HDL-C) and LDL cholesterol (LDL-C) with ISEC in 1150 non-diabetic obese children and adolescents using multivariable robust median regression. Th...

journal_title：Endocrine connections

authors： Bedogni G,Mari A,De Col A,Tamini S,Gastaldelli A,Sartorio A

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND/AIMS:Growth failure is a difficult but key aspect of care in children with anorexia nervosa (AN). The effects of hGH therapy have not been studied. The aim was to investigate the effect of hGH treatment on height velocity (HV) in children with AN. METHODS:We carried out a retrospective observational study. ...

journal_title：Endocrine connections

authors： Léger J,Fjellestad-Paulsen A,Bargiacchi A,Doyen C,Ecosse E,Carel JC,Le Heuzey MF

更新日期：2017-11-01 00:00:00

abstract：:This study aims to summarize and analyze the clinical manifestations, genetic characteristics, treatment modalities and long-term prognosis of congenital hyperinsulinemia (CHI) in Chinese children. Sixty children with CHI, who were treated at Beijing Children's Hospital from January 2014 to August 2017, and their fami...

journal_title：Endocrine connections

authors： Xu ZD,Zhang W,Liu M,Wang HM,Hui PP,Liang XJ,Yan J,Wu YJ,Sang YM,Zhu C,Ni GC

更新日期：2018-11-12 00:00:00

abstract：OBJECTIVE:Insulin-like growth factors are implicated in the development of diabetic nephropathy. IGF-binding protein 2 (IGFBP2) and IGF2 are expressed in the kidney, but their associations with diabetic nephropathy are unclear. We therefore tested the hypothesis that circulating levels of IGF2 and IGFBP2 predict longit...

journal_title：Endocrine connections

authors： Narayanan RP,Fu B,Heald AH,Siddals KW,Oliver RL,Hudson JE,Payton A,Anderson SG,White A,Ollier WE,Gibson JM

更新日期：2012-10-24 00:00:00

abstract：:The purpose of this study was to assess the relationship between vitamin D receptor gene (VDR) expression and prognostic factors in papillary thyroid cancer (PTC). mRNA sequencing and somatic mutation data from The Cancer Genome Atlas (TCGA) were analyzed. VDR mRNA expression was compared to clinicopathologic variable...

journal_title：Endocrine connections

authors： Choi JY,Yi JW,Lee JH,Song RY,Yu H,Kwon H,Chai YJ,Kim SJ,Lee KE

更新日期：2017-04-01 00:00:00

abstract：:The current investigation examined the association between the aging-related biomarkers dehydroepiandrosterone (DHEA) and telomere length (TL) in community-recruited African-American youth. The examination of DHEA included stress reactive, basal and diurnal sampling, in order to elucidate the underlying physiological ...

journal_title：Endocrine connections

authors： Dismukes AR,Meyer VJ,Shirtcliff EA,Theall KP,Esteves KC,Drury SS

更新日期：2016-05-01 00:00:00

abstract：:N/A. ...

journal_title：Endocrine connections

authors： Koehrle J

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively studied. Cardiac magnetic resonance imaging (CMR) contrast enhancement and novel sensitive T1 mapping to...

journal_title：Endocrine connections

authors： Grytaas MA,Sellevåg K,Thordarson HB,Husebye ES,Løvås K,Larsen TH

更新日期：2018-03-01 00:00:00

abstract：:Many biomarkers are associated with type 2 diabetes (T2D) risk in epidemiological observations. The aim of this study was to identify and summarize current evidence for causal effects of biomarkers on T2D. A systematic literature search in PubMed and EMBASE (until April 2015) was done to identify Mendelian randomizati...

journal_title：Endocrine connections

authors： Abbasi A

更新日期：2015-12-01 00:00:00

abstract：:Failure to suppress testosterone below 0.7 nM in castrated prostate cancer patients is associated with poor clinical outcomes. Testosterone levels in castrated patients are therefore routinely measured. Although mass spectrometry is the gold standard used to measure testosterone, most hospitals use an immunoassay meth...

journal_title：Endocrine connections

authors： Rouleau M,Lemire F,Déry M,Thériault B,Dubois G,Fradet Y,Toren P,Guillemette C,Lacombe L,Klotz L,Saad F,Guérette D,Pouliot F

更新日期：2019-02-01 00:00:00

abstract：AIMS:The cumulative effect of gestational diabetes mellitus (GDM) and hypertensive disorders of pregnancy (HDP) on postpartum cardio-metabolic diseases is equivocal. We aimed to assess the associations of GDM and HDP's individual and synergic contribution to risks of postpartum cardio-metabolic diseases (metabolic synd...

journal_title：Endocrine connections

authors： Li LJ,Aris IM,Su LL,Chong YS,Wong TY,Tan KH,Wang JJ

更新日期：2018-03-01 00:00:00

abstract：:Primary hyperparathyroidism (PHPT) is a common endocrinopathy, frequently caused by a parathyroid adenoma, rarely by a parathyroid carcinoma that lacks effective oncological treatment. As the majority of cases are present in postmenopausal women, oestrogen signalling has been implicated in the tumourigenesis. Oestroge...

journal_title：Endocrine connections

authors： Haglund F,Rosin G,Nilsson IL,Juhlin CC,Pernow Y,Norenstedt S,Dinets A,Larsson C,Hartman J,Höög A

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The value of postoperative radiotherapy in the treatment of medullary thyroid carcinoma (MTC) has not been unequivocally demonstrated. Therefore our study aimed to answer the question of whether adjuvant radiotherapy showed any impact on the risk of local recurrence and whether there were any differences in ...

journal_title：Endocrine connections

authors： Kukulska A,Krajewska J,Kolosza Z,Paliczka-Cieslik E,Kropinska A,Pawlaczek A,Puch Z,Ficek K,Lisik T,Sygula D,Wygoda Z,Roskosz J,Wydmanski J,Jarzab B

更新日期：2019-11-01 00:00:00

abstract：CONTEXT:Women with polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease (CVD), and biomarkers can be used to detect early subclinical CVD. Midregional-pro-adrenomedullin (MR-proADM), midregional-pro-atrial natriuretic peptide (MR-proANP) and copeptin are all associated with CVD and part of ...

journal_title：Endocrine connections

authors： Frøssing S,Nylander M,Kistorp C,Skouby SO,Faber J

更新日期：2018-01-01 00:00:00

abstract：Purpose:Gallbladder neuroendocrine neoplasm (GB-NEN) is a relatively rare neoplasm, accounting for 0.5% of all neuroendocrine neoplasm cases and 2.1% of gallbladder cancers. Because of the limited understanding of GB-NEN, the aim of this study was to explore the clinicopathology and survival of GB-NEN patients selected...

journal_title：Endocrine connections

authors： Cen D,Liu H,Wan Z,Lin Z,Wang Y,Xu J,Liang Y

更新日期：2019-09-01 00:00:00

abstract：:Hormonal cancers affect over 400,000 men and women and contribute collectively to over 100,000 deaths in the United States alone. Thanks to advances in the understanding of these cancers at the molecular level and to the discovery of several disease-modifying therapeutics, the last decade has seen a plateauing or even...

journal_title：Endocrine connections

authors： Ulm M,Ramesh AV,McNamara KM,Ponnusamy S,Sasano H,Narayanan R

更新日期：2019-02-01 00:00:00

abstract：:According to its incidence patterns, colorectal cancer (CRC) tends to occur more frequently in males than in females, and the evidence shows that CRC is a hormone-related tumor. These findings indicate that androgen receptor (AR) gene methylation might be important for the regulation of the CRC risk in the different s...

journal_title：Endocrine connections

authors： Xia T,Sun H,Huang H,Bi H,Pu R,Zhang L,Zhang Y,Liu Y,Xu J,Onwuka JU,Liu Y,Cui B,Zhao Y

更新日期：2019-07-01 00:00:00