Feline Foamy Virus Infection: Characterization of Experimental Infection and Prevalence of Natural Infection in Domestic Cats with and without Chronic Kidney Disease.

abstract：:The non-structural protein NSs of the Phenuiviridae family members appears to have a role in the host immunity escape. The stability of Toscana virus (TOSV) NSs protein was tested by a cycloheximide (CHX) chase approach on cells transfected with NSs deleted versions fused to a reporter gene. The presence of intrinsica...

journal_title：Viruses

authors： Gori Savellini G,Bini L,Gagliardi A,Anichini G,Gandolfo C,Prathyumnan S,Cusi MG

更新日期：2020-10-12 00:00:00

abstract：:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current COVID-19 pandemic. The 3' untranslated region (UTR) of this β-CoV contains essential cis-acting RNA elements for the viral genome transcription and replication. These elements include an equilibrium between an extended bulged s...

journal_title：Viruses

authors： Zhao J,Qiu J,Aryal S,Hackett JL,Wang J

更新日期：2020-12-21 00:00:00

abstract：:The human cytomegalovirus (HCMV) terminase complex is part of DNA-packaging machinery that delivers a unit-length genome into a procapsid. Sequence comparison of herpesvirus homologs allowed us to identify a potential LATLNDIERFL and zinc finger pattern in N-terminal part of pUL56. Recombinant viruses were generated w...

journal_title：Viruses

authors： Ligat G,Couvreux A,Cazal R,Alain S,Hantz S

更新日期：2019-11-26 00:00:00

abstract：:Recently, Alves-Freitas and colleagues [...]. ...

journal_title：Viruses

authors： Bejerman N,Dietzgen RG

更新日期：2019-03-07 00:00:00

abstract：:Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases, causing significant morbidity and mortality and posing a great threat to human health. Because of the diversity of influenza virus strains and drug resistance to the current direct antiviral agents, there ha...

journal_title：Viruses

authors： Zhang L,Chen J,Ke C,Zhang H,Zhang S,Tang W,Liu C,Liu G,Chen S,Hu A,Sun W,Xiao Y,Liu M,Chen X

更新日期：2020-05-18 00:00:00

abstract：:Simian hemorrhagic fever virus (SHFV) causes a fulminant and typically lethal viral hemorrhagic fever (VHF) in macaques (Cercopithecinae: Macaca spp.) but causes subclinical infections in patas monkeys (Cercopithecinae: Erythrocebus patas). This difference in disease course offers a unique opportunity to compare host ...

journal_title：Viruses

authors： Cornish JP,Moore IN,Perry DL,Lara A,Minai M,Promeneur D,Hagen KR,Virtaneva K,Paneru M,Buechler CR,O'Connor DH,Bailey AL,Cooper K,Mazur S,Bernbaum JG,Pettitt J,Jahrling PB,Kuhn JH,Johnson RF

更新日期：2019-01-15 00:00:00

abstract：:Monkeypox is a smallpox-like illness that can be accompanied by a range of significant medical complications. To date there are no standard or optimized guidelines for the clinical management of monkeypox (MPX) patients, particularly in low-resource settings. Consequently, patients can experience protracted illness an...

journal_title：Viruses

authors： Reynolds MG,McCollum AM,Nguete B,Shongo Lushima R,Petersen BW

更新日期：2017-12-12 00:00:00

abstract：:Streptococcus thermophilus is considered one of the most important species for the dairy industry. Due to their diffusion in dairy environments, bacteriophages can represent a threat to this widely used bacterial species. Despite the presence of a CRISPR-Cas system in the S. thermophilus genome, some lysogenic strains...

journal_title：Viruses

authors： da Silva Duarte V,Giaretta S,Campanaro S,Treu L,Armani A,Tarrah A,Oliveira de Paula S,Giacomini A,Corich V

更新日期：2018-12-22 00:00:00

abstract：:In the midst of the SARS-CoV-2/Covid-19 outbreak the need for research into, and development of, antiviral agents is brought into sharp focus worldwide for scientists, governments and the public alike [...]. ...

journal_title：Viruses

authors： Adamson CS

更新日期：2020-04-07 00:00:00

abstract：:Tospovirus is a tripartite negative stranded RNA virus and is considered as one of the most devastating plant viruses. Successful virus infection in plant requires many host factors. To date, very few host factors have been identified as important in Tospovirus infection in plants. We reported earlier that NSm protein...

journal_title：Viruses

authors： Qian X,Xiang Q,Yang T,Ma H,Ding XS,Tao X

更新日期：2018-11-17 00:00:00

abstract：:Human noroviruses (HuNoVs) are a leading cause of acute gastroenteritis worldwide. HuNoV infections lead to substantial societal and economic burdens. There are currently no licensed vaccines or therapeutics for the prevention or treatment of HuNoVs. A lack of well-characterized in vitro and in vivo infection models h...

journal_title：Viruses

authors： Todd KV,Tripp RA

更新日期：2019-02-12 00:00:00

abstract：:Circoviruses infect a variety of animal species and have small (~1.8-2.2 kb) circular single-stranded DNA genomes. Recently a penguin circovirus (PenCV) was identified associated with an Adélie Penguin (Pygoscelis adeliae) with feather disorder and in the cloacal swabs of three asymptomatic Adélie Penguins at Cape Cro...

journal_title：Viruses

authors： Levy H,Fiddaman SR,Djurhuus A,Black CE,Kraberger S,Smith AL,Hart T,Varsani A

更新日期：2020-08-06 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the etiological agent for a serious lower respiratory tract disease responsible for close to 200,000 annual deaths worldwide. The first infection is generally most severe, while re-infections usually associate with a milder disease. This observation and the finding that re-infecti...

journal_title：Viruses

authors： Rudraraju R,Jones BG,Sealy R,Surman SL,Hurwitz JL

更新日期：2013-02-05 00:00:00

abstract：:In July 2018, a novel avian influenza virus (A/Mandarin duck/South Korea/KNU18-12/2018(H11N9)) was isolated from Mandarin ducks in South Korea. Phylogenetic and molecular analyses were conducted to characterize the genetic origins of the H11N9 strain. Phylogenetic analysis indicated that eight gene segments of strain ...

journal_title：Viruses

authors： Tuong HT,Nguyen NM,Sung HW,Park H,Yeo SJ

更新日期：2020-02-12 00:00:00

abstract：:Exosomes are extracellular vesicles released upon fusion of multivesicular bodies(MVBs) with the cellular plasma membrane. They originate as intraluminal vesicles (ILVs) during the process of MVB formation. Exosomes were shown to contain selectively sorted functional proteins, lipids, and RNAs, mediating cell-to-cell ...

journal_title：Viruses

authors： Alenquer M,Amorim MJ

更新日期：2015-09-17 00:00:00

abstract：:Samples of two Ageratum conyzoides, one Sonchus oleraceus and one turnip (Brassica rapa var. rapa) exhibiting virus-like symptoms were collected from Pakistan and Nepal. Full-length begomovirus clones were obtained from the four plant samples and betasatellite clones from three of these. The begomovirus sequences were...

journal_title：Viruses

authors： Tahir M,Amin I,Haider MS,Mansoor S,Briddon RW

更新日期：2015-02-10 00:00:00

abstract：:The hepatitis B virus (HBV) infects hepatocytes, which are the main cell type composing a human liver. However, the liver is enriched with immune cells, particularly innate cells (e.g., myeloid cells, natural killer and natural killer T-cells (NK/NKT), dendritic cells (DCs)), in resting condition. Hence, the study of ...

journal_title：Viruses

authors： Faure-Dupuy S,Lucifora J,Durantel D

更新日期：2017-04-28 00:00:00

abstract：:Porcine circovirus type 2 (PCV2) is the etiological agent of porcine circovirus diseases and porcine circovirus-associated diseases (PCVDs/PCVADs). However, the pathogenesis of PCV2 is not fully understood. We previously found that 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is negatively associated with P...

journal_title：Viruses

authors： Ouyang T,Niu G,Zhang Y,Liu X,Zhang X,Zhang S,Geng Y,Pang D,Ouyang H,Ren L

更新日期：2019-06-11 00:00:00

abstract：:Hepatitis B virus (HBV) persistence is at the basis of HBV reactivation as a consequence of chemotherapy and immunosuppressive treatments. The identification of early viral replication indicators and markers of effective HBV immunological control would be useful in monitoring patients who are at risk of potential vira...

journal_title：Viruses

authors： Svicher V,Salpini R,Malagnino V,Piermatteo L,Alkhatib M,Cerva C,Sarmati L

更新日期：2019-08-25 00:00:00

abstract：:The chikungunya virus (CHIKV) is an emerging pathogen with widespread distribution in regions of Africa, India, and Asia that threatens to spread into temperate climates with the introduction of its major vector, Aedes albopictus. CHIKV causes a disease frequently misdiagnosed as dengue fever, with potentially life-th...

journal_title：Viruses

authors： Mishra P,Furey C,Balaraman V,Fraser MJ

更新日期：2016-06-10 00:00:00

abstract：:The assembly of a hexameric lattice of retroviral immature particles requires the involvement of cell factors such as proteins and small molecules. A small, negatively charged polyanionic molecule, myo-inositol hexaphosphate (IP6), was identified to stimulate the assembly of immature particles of HIV-1 and other lenti...

journal_title：Viruses

authors： Dostálková A,Vokatá B,Kaufman F,Ulbrich P,Ruml T,Rumlová M

更新日期：2021-01-18 00:00:00

abstract：:Nasopharyngeal cancer (NPC) is associated with Epstein Barr virus (EBV) infection. However different viral strains have been implicated in NPC worldwide. This study aimed to detect and characterize EBV in patients diagnosed with NPC in Ghana. A total of 55 patients diagnosed with NPC by CT scan and endoscopy were age-...

journal_title：Viruses

authors： Ayee R,Ofori MEO,Tagoe EA,Languon S,Searyoh K,Armooh L,Bilson-Amoah E,Baidoo K,Kitcher E,Wright E,Quaye O

更新日期：2020-07-16 00:00:00

abstract：:Human cytomegalovirus (HCMV), the largest human herpesvirus, infects a majority of the world's population. Like all herpesviruses, following primary productive infection, HCMV establishes a life-long latent infection, from which it can reactivate years later to produce new, infectious virus. Despite the presence of a ...

journal_title：Viruses

authors： McSharry BP,Avdic S,Slobedman B

更新日期：2012-10-25 00:00:00

abstract：:The bacteriophage lambda replication initiation protein P exhibits a toxic effect on its Escherichia coli (E. coli) host, likely due to the formation of a dead-end P-DnaB complex, sequestering the replicative DnaB helicase from further activity. Intracellular expression of P triggers SOS-independent cellular filamenta...

journal_title：Viruses

authors： Hayes S,Wang W,Rajamanickam K,Chu A,Banerjee A,Hayes C

更新日期：2016-06-22 00:00:00

abstract：:Via virome sequencing, six viruses were detected from Magnaporthe oryzae strains YC81-2, including one virus in the family Tombusviridae, one virus in the family Narnaviridae and four viruses in the family Botourmiaviridae. Since the RNA-dependent RNA polymerase (RdRp) of one botourmiavirus show the highest identity (...

journal_title：Viruses

authors： Liu Y,Zhang L,Esmael A,Duan J,Bian X,Jia J,Xie J,Cheng J,Fu Y,Jiang D,Lin Y

更新日期：2020-12-03 00:00:00

abstract：:Influenza A viruses (IAV) have been a major public health threat worldwide, and options for antiviral therapy become increasingly limited with the emergence of drug-resisting virus strains. New and effective anti-IAV drugs, especially for highly pathogenic influenza, with different modes of action, are urgently needed...

journal_title：Viruses

authors： Ye M,Liao Y,Wu L,Qi W,Choudhry N,Liu Y,Chen W,Song G,Chen J

更新日期：2020-02-18 00:00:00

abstract：:Respiratory viruses cause disease in humans characterized by an abrupt onset of symptoms. Studies in humans and animal models have shown that symptoms are not immediate and appear days or even weeks after infection. Since the initial symptoms are a manifestation of virus recognition by elements of the innate immune re...

journal_title：Viruses

authors： Hermesh T,Moltedo B,López CB,Moran TM

更新日期：2010-11-01 00:00:00

abstract：:Influenza A viruses (IAV) carrying reporter genes provide a powerful tool to study viral infection and pathogenesis in vivo, however, incorporating a non-essential gene into the IAV genome often results in virus attenuation and genetic instability. Very few studies have systematically compared different reporter IAVs,...

journal_title：Viruses

authors： Zhao X,Wang L,Cui Q,Li P,Wang Y,Zhang Y,Yang Y,Rong L,Du R

更新日期：2018-11-30 00:00:00

abstract：:The Pneumoviridae family includes human metapneumovirus (HMPV) and human orthopneumovirus, which is also known as a respiratory syncytial virus (HRSV). These are large enveloped, negative single-strand RNA viruses. HMPV and HRSV are the human members, which commonly infect children. HMPV, which was discovered in 2001,...

journal_title：Viruses

authors： Diab M,Schmiedel D,Seidel E,Bacharach E,Mandelboim O

更新日期：2020-07-20 00:00:00

abstract：:Enteric viral co-infections, infections involving more than one virus, have been reported for a diverse group of etiological agents, including rotavirus, norovirus, astrovirus, adenovirus, and enteroviruses. These pathogens are causative agents for acute gastroenteritis and diarrheal disease in immunocompetent and imm...

journal_title：Viruses

authors： Makimaa H,Ingle H,Baldridge MT

更新日期：2020-08-18 00:00:00