Clinical Characterization of Host Response to Simian Hemorrhagic Fever Virus Infection in Permissive and Refractory Hosts: A Model for Determining Mechanisms of VHF Pathogenesis.

abstract：:Metagenomics studies have accelerated the discovery of novel or divergent viruses of the honey bee. However, most of these studies predominantly focused on RNA viruses, and many suffer from the relatively low abundance of viral nucleic acids in the samples (i.e., compared to that of the host). Here, we explored the vi...

journal_title：Viruses

authors： Gebremedhn H,Deboutte W,Schoonvaere K,Demaeght P,De Smet L,Amssalu B,Matthijnssens J,de Graaf DC

更新日期：2020-10-27 00:00:00

abstract：:Internal ribosome entry is a key mechanism for viral protein synthesis in a subset of RNA viruses. Cricket paralysis virus (CrPV), a member of Dicistroviridae, has a positive-sense single strand RNA genome that contains two internal ribosome entry sites (IRES), a 5'untranslated region (5'UTR) and intergenic region (IG...

journal_title：Viruses

authors： Khong A,Bonderoff JM,Spriggs RV,Tammpere E,Kerr CH,Jackson TJ,Willis AE,Jan E

更新日期：2016-01-19 00:00:00

abstract：:On average, there are 3-5 million severe cases of influenza virus infections globally each year. Seasonal influenza vaccines provide limited protection against divergent influenza strains. Therefore, the development of a universal influenza vaccine is a top priority for the NIH. Here, we report a comprehensive summary...

journal_title：Viruses

authors： Corder BN,Bullard BL,Poland GA,Weaver EA

更新日期：2020-10-20 00:00:00

abstract：:A field study was undertaken to (i) measure the prevalence of feline leukaemia virus (FeLV) exposure and FeLV infection in a cross-section of healthy Australian pet cats; and (ii) investigate the outcomes following natural FeLV exposure in two Australian rescue facilities. Group 1 (n = 440) consisted of healthy client...

journal_title：Viruses

authors： Westman M,Norris J,Malik R,Hofmann-Lehmann R,Harvey A,McLuckie A,Perkins M,Schofield D,Marcus A,McDonald M,Ward M,Hall E,Sheehy P,Hosie M

更新日期：2019-05-31 00:00:00

abstract：:At the end of 2019, a new disease appeared and spread all over the world, the COVID-19, produced by the coronavirus SARS-CoV-2. As a consequence of this worldwide health crisis, the scientific community began to redirect their knowledge and resources to fight against it. Here we summarize the recent research on viruse...

journal_title：Viruses

authors： Fernandez-Garcia L,Pacios O,González-Bardanca M,Blasco L,Bleriot I,Ambroa A,López M,Bou G,Tomás M

更新日期：2020-10-16 00:00:00

abstract：:The subgroup A through E avian sarcoma and leukosis viruses (ASLV(A) through ASLV(E)) are a group of highly related alpharetroviruses that have evolved their envelope glycoproteins to use different receptors to enable efficient virus entry due to host resistance and/or to expand host range. Previously, we demonstrated...

journal_title：Viruses

authors： Munguia A,Federspiel MJ

更新日期：2019-06-05 00:00:00

abstract：:HIV-1 Gag polyprotein orchestrates the assembly of viral particles. Its C-terminus consists of the nucleocapsid (NC) domain that interacts with nucleic acids, and p1 and p6, two unstructured regions, p6 containing the motifs to bind ALIX, the cellular ESCRT factor TSG101 and the viral protein Vpr. The processing of Ga...

journal_title：Viruses

authors： Mouhand A,Pasi M,Catala M,Zargarian L,Belfetmi A,Barraud P,Mauffret O,Tisné C

更新日期：2020-09-29 00:00:00

abstract：:At the end of my doctoral studies, in 1988, I published a review article on the major steps of transcription and translation during the mammalian reovirus multiplication cycle, a topic that still fascinates me 30 years later. It is in the nature of scientific research to generate further questioning as new knowledge e...

journal_title：Viruses

authors： Lemay G

更新日期：2018-11-27 00:00:00

abstract：:Respiratory viruses cause disease in humans characterized by an abrupt onset of symptoms. Studies in humans and animal models have shown that symptoms are not immediate and appear days or even weeks after infection. Since the initial symptoms are a manifestation of virus recognition by elements of the innate immune re...

journal_title：Viruses

authors： Hermesh T,Moltedo B,López CB,Moran TM

更新日期：2010-11-01 00:00:00

abstract：:P4 is a mobile genetic element (MGE) that can exist as a plasmid or integrated into its Escherichia coli host genome, but becomes packaged into phage particles by a helper bacteriophage, such as P2. P4 is the original example of what we have termed "molecular piracy", the process by which one MGE usurps the life cycle...

journal_title：Viruses

authors： Kizziah JL,Rodenburg CM,Dokland T

更新日期：2020-08-27 00:00:00

abstract：:Bluetongue (BT) is an arthropod-borne viral disease of ruminants with serious trade and socio-economic implications. Although the disease has been reported in a number of countries in sub-Saharan Africa, there is currently no information on circulating serotypes and disease distribution in Zambia. Following surveillan...

journal_title：Viruses

authors： Chambaro HM,Sasaki M,Simulundu E,Silwamba I,Sinkala Y,Gonzalez G,Squarre D,Fandamu P,Lubaba CH,Munyeme M,Maseko A,Chimvwele C,Mataa L,Mooya LE,Mukubesa AN,Harima H,Samui KL,Munang'andu HM,Simuunza M,Nalubamba KS,Q

更新日期：2020-08-31 00:00:00

abstract：:Tailoring public health responses to growing HIV transmission clusters depends on accurately mapping the risk network through which it spreads and identifying acute infections that represent the leading edge of cluster growth. HIV transmission links, especially those involving persons with acute HIV infection (AHI), c...

journal_title：Viruses

authors： Campbell EM,Patala A,Shankar A,Li JF,Johnson JA,Westheimer E,Gay CL,Cohen SE,Switzer WM,Peters PJ

更新日期：2020-01-27 00:00:00

abstract：:The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS)...

journal_title：Viruses

authors： Jin Y,Yang H,Ji W,Wu W,Chen S,Zhang W,Duan G

更新日期：2020-03-27 00:00:00

abstract：:Human coronaviruses cause both upper and lower respiratory tract infections in humans. In 2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe respiratory illness. The 60-year-old man died as a result of renal and respiratory failure after admission to a hospital in Jeddah, Saudi A...

journal_title：Viruses

authors： Chafekar A,Fielding BC

更新日期：2018-02-24 00:00:00

abstract：:Thermobifida fusca is of biotechnological interest due to its ability to produce an array of plant cell wall hydrolytic enzymes. Nonetheless, only one T. fusca bacteriophage with genome information has been reported to date. This study was aimed at discovering more relevant bacteriophages to expand the existing knowle...

journal_title：Viruses

authors： Cheepudom J,Lin TL,Lee CC,Meng M

更新日期：2019-11-08 00:00:00

abstract：:We use a Species Distribution Modeling (SDM) approach along with Geographic Information Systems (GIS) techniques to examine the potential distribution of hantavirus pulmonary syndrome (HPS) caused by Andes virus (ANDV) in southern Argentina and, more precisely, define and estimate the area with the highest infection p...

journal_title：Viruses

authors： Andreo V,Neteler M,Rocchini D,Provensal C,Levis S,Porcasi X,Rizzoli A,Lanfri M,Scavuzzo M,Pini N,Enria D,Polop J

更新日期：2014-01-14 00:00:00

abstract：UNLABELLED:Cytomegalovirus (CMV) is a prevalent pathogen in the immunocompromised host and invasive pneumonia is a feared complication of the virus in this population. In this pediatric case series we characterized CMV lung infection in 15 non-HIV infected children (median age 3 years; IQR 0.2-4.9 years), using current...

journal_title：Viruses

authors： Restrepo-Gualteros SM,Jaramillo-Barberi LE,Gonzalez-Santos M,Rodriguez-Martinez CE,Perez GF,Gutierrez MJ,Nino G

更新日期：2014-05-07 00:00:00

abstract：:The Iridoviridae family are large viruses (∼120-200 nm) that contain a linear double-stranded DNA genome. The genomic size of Iridoviridae family members range from 105,903 bases encoding 97 open reading frames (ORFs) for frog virus 3 to 212,482 bases encoding 211 ORFs for Chilo iridescent virus. The family Iridovirid...

journal_title：Viruses

authors： Eaton HE,Ring BA,Brunetti CR

更新日期：2010-07-01 00:00:00

abstract：:Coronaviruses are enveloped RNA viruses capable of causing respiratory, enteric, or systemic diseases in a variety of mammalian hosts that vary in clinical severity from subclinical to fatal. The host range and tissue tropism are largely determined by the coronaviral spike protein, which initiates cellular infection b...

journal_title：Viruses

authors： Haake C,Cook S,Pusterla N,Murphy B

更新日期：2020-09-13 00:00:00

abstract：:Tospovirus is a tripartite negative stranded RNA virus and is considered as one of the most devastating plant viruses. Successful virus infection in plant requires many host factors. To date, very few host factors have been identified as important in Tospovirus infection in plants. We reported earlier that NSm protein...

journal_title：Viruses

authors： Qian X,Xiang Q,Yang T,Ma H,Ding XS,Tao X

更新日期：2018-11-17 00:00:00

abstract：:The RNA3 species of the beet necrotic yellow vein virus (BNYVV), a multipartite positive-stranded RNA phytovirus, contains the 'core' nucleotide sequence required for its systemic movement in Beta macrocarpa. Within this 'core' sequence resides a conserved "coremin" motif of 20 nucleotides that is absolutely essential...

journal_title：Viruses

authors： Flobinus A,Chevigny N,Charley PA,Seissler T,Klein E,Bleykasten-Grosshans C,Ratti C,Bouzoubaa S,Wilusz J,Gilmer D

更新日期：2018-03-19 00:00:00

abstract：:Severe fever with thrombocytopenia syndrome (SFTS) is a novel tick-borne infectious disease, therefore, the information on the whole genome of the SFTS virus (SFTSV) is still limited. This study demonstrates a nearly whole genome of the SFTSV identified in Osaka in 2017 and 2018 by next-generation sequencing (NGS). Th...

journal_title：Viruses

authors： Ikemori R,Aoyama I,Sasaki T,Takabayashi H,Morisada K,Kinoshita M,Ikuta K,Yumisashi T,Motomura K

更新日期：2021-01-25 00:00:00

abstract：:West Nile virus (WNV) is an important emerging neurotropic virus, responsible for increasingly severe encephalitis outbreaks in humans and horses worldwide. However, the mechanism by which the virus gains entry to the brain (neuroinvasion) remains poorly understood. Hypotheses of hematogenous and transneural entry hav...

journal_title：Viruses

authors： Suen WW,Prow NA,Hall RA,Bielefeldt-Ohmann H

更新日期：2014-07-18 00:00:00

abstract：:Heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar) was first diagnosed in Norway in 1999. The disease is caused by Piscine orthoreovirus-1 (PRV-1). The virus is prevalent in farmed Atlantic salmon, but not always associated with disease. Phylogeny and sequence analyses of 31 PRV-1 ge...

journal_title：Viruses

authors： Dhamotharan K,Tengs T,Wessel Ø,Braaen S,Nyman IB,Hansen EF,Christiansen DH,Dahle MK,Rimstad E,Markussen T

更新日期：2019-05-22 00:00:00

abstract：:RNA viruses are extraordinary evolution machines that efficiently ensure their replication by taking advantage of the association with viral and cellular components to form ribonucleic complexes (vRNPs) [...]. ...

journal_title：Viruses

authors： Bernacchi S

更新日期：2020-11-26 00:00:00

abstract：:One of the major obstacles that must be overcome in the design of effective lentiviral vaccines is the ability of lentiviruses to evolve in order to escape from neutralizing antibodies. The primary target for neutralizing antibodies is the highly variable viral envelope glycoprotein (Env), a glycoprotein that is essen...

journal_title：Viruses

authors： Hosie MJ,Pajek D,Samman A,Willett BJ

更新日期：2011-10-01 00:00:00

abstract：:An outbreak of winter dysentery, complicated by severe respiratory syndrome, occurred in January 2020 in a high production dairy cow herd located in a hilly area of the Calabria region. Of the 52 animals belonging to the farm, 5 (9.6%) died with severe respiratory distress, death occurring 3-4 days after the appearanc...

journal_title：Viruses

authors： Amoroso MG,Lucifora G,Degli Uberti B,Serra F,De Luca G,Borriello G,De Domenico A,Brandi S,Cuomo MC,Bove F,Riccardi MG,Galiero G,Fusco G

更新日期：2020-11-19 00:00:00

abstract：:Eukaryotic translation is a complex process composed of three main steps: initiation, elongation, and termination. During infections by RNA- and DNA-viruses, the eukaryotic translation machinery is used to assure optimal viral protein synthesis. Human immunodeficiency virus type I (HIV-1) uses several non-canonical pa...

journal_title：Viruses

authors： Guerrero S,Batisse J,Libre C,Bernacchi S,Marquet R,Paillart JC

更新日期：2015-01-19 00:00:00

abstract：:Despite worldwide efforts to understand the transmission dynamics of Zika virus (ZIKV), scanty evaluation has been made on the vector competence of Aedes aegypti fed directly on viremic human and non-human primates (NHPs). We blood-fed Ae. aegypti from two districts in Rio de Janeiro on six ZIKV infected pregnant rhes...

journal_title：Viruses

authors： Fernandes RS,David MR,De Abreu FVS,Ferreira-de-Brito A,Gardinali NR,Lima SMB,Andrade MCR,Kugelmeier T,Oliveira JM,Pinto MA,Lourenço-de-Oliveira R

更新日期：2020-11-24 00:00:00

abstract：:Pectobacterium atrosepticum is a phytopathogen of economic importance as it is the causative agent of potato blackleg and soft rot. Here we describe the Pectobacterium phage vB_PatP_CB5 (abbreviated as CB5), which specifically infects the bacterium. The bacteriophage is characterized in detail and TEM micrographs indi...

journal_title：Viruses

authors： Buttimer C,Lucid A,Neve H,Franz CMAP,O'Mahony J,Turner D,Lavigne R,Coffey A

更新日期：2018-07-26 00:00:00