Reduced forced vital capacity is independently associated with ethnicity, metabolic factors and respiratory symptoms in a Caribbean population: a cross-sectional study.

abstract：BACKGROUND:People with cystic fibrosis (CF) may work in healthcare settings risking nosocomial pathogen acquisition. The aim of this study was to determine the incidence of methicillin-resistant Staphylococcus aureus (MRSA) infection in adult healthcare workers with CF (HCWcf). METHODS:Data was collected in this obser...

journal_title：BMC pulmonary medicine

authors： Wood ME,Sherrard LJ,Ramsay KA,Yerkovich ST,Reid DW,Kidd TJ,Bell SC

更新日期：2016-05-11 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a disease with poor prognosis mainly affecting males. Differences in clinical presentation between genders may be important both for the diagnostic work-up and for follow-up. In the present study, we therefore explored potential gender differences at presentation in a S...

journal_title：BMC pulmonary medicine

authors： Kalafatis D,Gao J,Pesonen I,Carlson L,Sköld CM,Ferrara G

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:To evaluate the diagnostic accuracy of the integrated Practical Approach to Lung Health in South Africa (PALSA) guideline in identifying patients requiring bacteriological screening for tuberculosis (TB), and to determine which clinical features best predict suspected and bacteriologically-confirmed tubercul...

journal_title：BMC pulmonary medicine

authors： English RG,Bachmann MO,Bateman ED,Zwarenstein MF,Fairall LR,Bheekie A,Majara BP,Lombard C,Scherpbier R,Ottomani SE

更新日期：2006-08-25 00:00:00

abstract：BACKGROUND:Reduced lung function in patients with chronic obstructive pulmonary disease (COPD) is likely due to both environmental and genetic factors. We report here a targeted high-throughput DNA sequencing approach to identify new and previously known genetic variants in a set of candidate genes for COPD. METHODS:E...

journal_title：BMC pulmonary medicine

authors： Matsson H,Söderhäll C,Einarsdottir E,Lamontagne M,Gudmundsson S,Backman H,Lindberg A,Rönmark E,Kere J,Sin D,Postma DS,Bossé Y,Lundbäck B,Klar J

更新日期：2016-11-11 00:00:00

abstract：BACKGROUND:Eotaxin proteins are a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases. Since inflammation is often associated with an increased generation of reactive oxygen species (ROS), oxidative stress is a mechanistically imperative factor in asthma. Ast...

journal_title：BMC pulmonary medicine

authors： Cho IH,Gong JH,Kang MK,Lee EJ,Park JH,Park SJ,Kang YH

更新日期：2014-07-29 00:00:00

abstract：BACKGROUND:Vascular air embolism (VAE) is a rare but important complication that has not been paid enough attention to in the medical process such as surgery and anesthesia. CASE PRESENTATION:We report for the first time that a 54-year-old male patient with central lung cancer developed severe complications of CAE aft...

journal_title：BMC pulmonary medicine

authors： Mo Y,Lin L,Yan J,Zhong C,Kuang J,Guo Q,Li D,Wu M,Sui Z,Zhang J

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:The lung-protective ventilation bundle has been shown to reduce mortality in adult acute respiratory distress syndrome (ARDS). This concept has expanded to other areas of acute adult ventilation and is recommended for pediatric ventilation. A component of lung-protective ventilation relies on a prediction of...

journal_title：BMC pulmonary medicine

authors： Martin DC,Richards GN

更新日期：2017-05-23 00:00:00

abstract：BACKGROUND:Little is known about whether or how supplemental oxygen affects patients with pulmonary fibrosis. METHODS/DESIGN:A mixed-methods study is described. Patients with pulmonary fibrosis, informal caregivers of pulmonary fibrosis patients and practitioners who prescribe supplemental oxygen will be interviewed t...

journal_title：BMC pulmonary medicine

authors： Belkin A,Fier K,Albright K,Baird S,Crowe B,Eres L,Korn M,Maginn L,McCormick M,Root ED,Vierzba T,Wamboldt FS,Swigris JJ

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Although cigarette smoking may have a negative impact on the clinical outcome of pulmonary tuberculosis (PTB), few studies have investigated the impact of smoking-associated lung diseases. Emphysema is a major pathological finding of smoking-related lung damage. We aimed to clarify the effect of emphysema on...

journal_title：BMC pulmonary medicine

authors： Takasaka N,Seki Y,Fujisaki I,Uchiyama S,Matsubayashi S,Sato A,Yamanaka Y,Odashima K,Kazuyori T,Seki A,Takeda H,Ishikawa T,Kuwano K

更新日期：2020-11-07 00:00:00

abstract：BACKGROUND:ALK-rearrangement is observed in < 5% non-small cell lung cancer (NSCLC) cases and prior to the advent of oral tyrosine kinase inhibitors, the natural history of oncogenic NSCLC was typically poor. Literature relating to regression of treatment-naïve NSCLC is limited, and regression without treatment has not...

journal_title：BMC pulmonary medicine

authors： Walls M,Walls GM,James JA,Crawford KT,Abdulkhalek H,Lynch TB,Peace AJ,McManus TE,Evans OR

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Idiopathic Pulmonary Fibrosis (IPF) is a fatal fibrotic lung disease occurring predominantly in middle-aged and older adults. The traditional diagnostic classification of IPF is based on clinical, radiological, and histopathological features. However, the considerable heterogeneity in IPF presentation sugges...

journal_title：BMC pulmonary medicine

authors： Wang Y,Yella J,Chen J,McCormack FX,Madala SK,Jegga AG

更新日期：2017-10-20 00:00:00

abstract：BACKGROUND:Onset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in relation to allergy. The purpose of the study was to assess age-specific incidence of allergic and non-allergic asthma. METHODS:Questionnaires were se...

journal_title：BMC pulmonary medicine

authors： Pakkasela J,Ilmarinen P,Honkamäki J,Tuomisto LE,Andersén H,Piirilä P,Hisinger-Mölkänen H,Sovijärvi A,Backman H,Lundbäck B,Rönmark E,Kankaanranta H,Lehtimäki L

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:Convenient approaches for accurate biopsy are extremely important to the diagnosis of lung cancer. We aimed to systematically review the clinical updates and development trends of approaches for biopsy, i.e., CT-guided PTNB (Percutaneous Transthoracic Needle Biopsy), ENB (Electromagnetic Navigation Bronchosc...

journal_title：BMC pulmonary medicine

authors： Deng CJ,Dai FQ,Qian K,Tan QY,Wang RW,Deng B,Zhou JH

更新日期：2018-09-03 00:00:00

abstract：BACKGROUND:The FACED score is an easy-to-use multidimensional grading system that has demonstrated an excellent prognostic value for mortality in patients with bronchiectasis. A Spanish group developed the score but no multicenter international validation has yet been published. METHODS:Retrospective and multicenter s...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Pereira MC,Gramblicka G,Cavalcanti-Lundgren F,de Figueiredo MF,Arancibia F,Rached S,de la Rosa D,Máiz-Carro L,Girón R,Olveira C,Prados C,Martinez-Garcia MA

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) have increased cardiovascular risk. Natriuretic peptides (NP) in other populations are useful in identifying cardiovascular disease, stratifying risk, and guiding therapy. METHODS:We performed a systematic literature review to examine NP in COPD, ut...

journal_title：BMC pulmonary medicine

authors： Hawkins NM,Khosla A,Virani SA,McMurray JJ,FitzGerald JM

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae is one of the most common pathogens causing community acquired pneumonia in children. Although the rate of macrolide-refractory Mycoplasma pneumoniae (MRMP) has increased, systemic glucocorticoids as a treatment option has not been validated yet. The purpose of this study was to assess ...

journal_title：BMC pulmonary medicine

authors： Kim HS,Sol IS,Li D,Choi M,Choi YJ,Lee KS,Seo JH,Lee YJ,Yang HJ,Kim HH

更新日期：2019-12-18 00:00:00

abstract：BACKGROUND:Systemic inflammation plays an important role in the initiation, promotion, and progression of lung carcinogenesis. In patients with non-small cell lung cancer (NSCLC), fibrinogen levels correlate with neoplasia. Here we compared the effects of pulmonary rehabilitation (PR) with chest physical therapy (CPT) ...

journal_title：BMC pulmonary medicine

authors： Morano MT,Mesquita R,Da Silva GP,Araújo AS,Pinto JM,Neto AG,Viana CM,De Moraes Filho MO,Pereira ED

更新日期：2014-07-28 00:00:00

abstract：BACKGROUND:Asthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized control trial (RCT) is to evaluate short-term (end of rehabilitation) and intermediate-term effectiveness ...

journal_title：BMC pulmonary medicine

authors： Schultz K,Seidl H,Jelusic D,Wagner R,Wittmann M,Faller H,Nowak D,Schuler M

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:The accuracy of currently available same-day diagnostic tools (smear microscopy and conventional nucleic acid amplification tests) for pleural tuberculosis (TB) is sub-optimal. Newer technologies may offer improved detection. METHODS:Smear-microscopy, adenosine deaminase (ADA), interferon gamma (IFN-γ), and...

journal_title：BMC pulmonary medicine

authors： Meldau R,Peter J,Theron G,Calligaro G,Allwood B,Symons G,Khalfey H,Ntombenhle G,Govender U,Binder A,van Zyl-Smit R,Dheda K

更新日期：2014-04-08 00:00:00

abstract：BACKGROUND:Community-acquired pneumonia (CAP) requires urgent and specific antimicrobial therapy. However, the causal pathogen is typically unknown at the point when anti-infective therapeutics must be initiated. Physicians synthesize information from diverse data streams to make appropriate decisions. Artificial intel...

journal_title：BMC pulmonary medicine

authors： Lhommet C,Garot D,Grammatico-Guillon L,Jourdannaud C,Asfar P,Faisy C,Muller G,Barker KA,Mercier E,Robert S,Lanotte P,Goudeau A,Blasco H,Guillon A

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:Fine needle aspiration is an important tool for diagnosis and preoperative evaluation of solitary nodules of the lung. It provides a definitive diagnosis in most patients at low cost with minimal trauma. However, because of the nature of the study and the presentation of the cells in a more distorted and inc...

journal_title：BMC pulmonary medicine

authors： Torkian B,Kanthan R,Burbridge B

更新日期：2003-09-08 00:00:00

abstract：BACKGROUND:A variety of large randomized controlled trials (RCT's) evaluating pharmacotherapy in chronic obstructive pulmonary disease (COPD) patients does exist. One of the drugs that has been tested is the new long-acting anticholinergic glycopyrronium bromide. METHODS:As the generalizability of results from RCT's i...

journal_title：BMC pulmonary medicine

authors： Kardos P,Vogelmeier C,Buhl R,Criée CP,Worth H

更新日期：2015-01-12 00:00:00

abstract：BACKGROUND:Mechanical ventilation (MV), compared to spontaneous breathing (SB), has been found to increase abdominal edema and inflammation in experimental sepsis. Our hypothesis was that in primary acute respiratory distress syndrome (ARDS) MV would enhance inflammation and edema in the abdomen. METHODS:Thirteen pigl...

journal_title：BMC pulmonary medicine

authors： Marchesi S,Hedenstierna G,Hata A,Feinstein R,Larsson A,Larsson AO,Lipcsey M

更新日期：2020-04-25 00:00:00

abstract：BACKGROUND:Breathlessness is a common and distressing symptom affecting many patients with advanced disease both from malignant and non-malignant origin. A combination of pharmacological and non-pharmacological measures is necessary to treat this symptom successfully. Breathlessness services in various compositions aim...

journal_title：BMC pulmonary medicine

authors： Bausewein C,Jolley C,Reilly C,Lobo P,Kelly J,Bellas H,Madan P,Panell C,Brink E,De Biase C,Gao W,Murphy C,McCrone P,Moxham J,Higginson IJ

更新日期：2012-09-19 00:00:00

abstract：BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR) is a biomarker of inflammation in chronic obstructive pulmonary disease (COPD) patients. But, a meaningful threshold and the longitudinal changes are unknown. We aimed to investigate the association between NLR and the clinical characteristics of COPD patients and to dete...

journal_title：BMC pulmonary medicine

authors： Sakurai K,Chubachi S,Irie H,Tsutsumi A,Kameyama N,Kamatani T,Koh H,Terashima T,Nakamura H,Asano K,Betsuyaku T

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:The dysfunction of airway epithelial barrier is closely related to the pathogenesis of asthma. Secreted Hsp90α participates in inflammation and Hsp90 inhibitor protects endothelial dysfunction. In the current study, we aimed to explore the role of secreted Hsp90α in asthmatic airway epithelial barrier functi...

journal_title：BMC pulmonary medicine

authors： Ye C,Huang C,Zou M,Hu Y,Luo L,Wei Y,Wan X,Zhao H,Li W,Cai S,Dong H

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:This study aims to investigate the effects of CCAAT/enhancer binding protein alpha (C/EBPα) overexpression on cell proliferation, apoptosis and surfactant protein-C(SP-C) in alveolar epithelial type II (AEC II) cells after exposure to hyperoxia. METHODS:pcDNA3.1(+)-C/EBPα plasmid or air-empty vector were tr...

journal_title：BMC pulmonary medicine

authors： Lu H,Chen X,Lu Y,Zhu H,Tang W,Wang Q

更新日期：2019-08-06 00:00:00

abstract：:Following publication of the original article [1], the author flagged aspects of the article that affected readability of some of the article's scientific content. ...

journal_title：BMC pulmonary medicine

authors： Fuchs O,Bahmer T,Weckmann M,Dittrich AM,Schaub B,Rösler B,Happle C,Brinkmann F,Ricklefs I,König IR,Watz H,Rabe KF,Kopp MV,Hansen G,von Mutius E,ALLIANCE Study Group as part of the German Centre for Lung Research (DZL).

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:Plasma levels of cell-free DNA (cf-DNA) are known to be elevated in sepsis and high levels are associated with a poor prognosis. Mechanical ventilation affects systemic inflammation in which lung-protective ventilation attenuates the inflammatory response. The aim was to study the effect of a lung protective...

journal_title：BMC pulmonary medicine

authors： Nyberg A,Larsson A,Jylhävä J,Hurme M,Sperber J,Lipcsey M,Castegren M

更新日期：2020-07-31 00:00:00

abstract：BACKGROUND:Inhaled bronchodilators including long-acting beta-agonist (LABA) and long-acting muscarinic antagonist (LAMA) play a central role in the treatment of stable chronic obstructive pulmonary disease (COPD). However, it is still unclear whether LABA or LAMA should be used for the initial treatment. Therefore, we...

journal_title：BMC pulmonary medicine

authors： Koarai A,Sugiura H,Yamada M,Ichikawa T,Fujino N,Kawayama T,Ichinose M

更新日期：2020-04-29 00:00:00