Abstract:
BACKGROUND:People with cystic fibrosis (CF) may work in healthcare settings risking nosocomial pathogen acquisition. The aim of this study was to determine the incidence of methicillin-resistant Staphylococcus aureus (MRSA) infection in adult healthcare workers with CF (HCWcf). METHODS:Data was collected in this observational study on MRSA acquisition from 405 CF patients attending an adult CF centre in Australia between 2001-2012. Demographic and clinical characteristics were compared between HCWcf and non-HCWcf. A sub-analysis was subsequently performed to compare demographic and clinical characteristics between those patients (HCWcf versus non-HCWcf) that acquired MRSA. We also investigated rates of chronic MRSA infection and the outcome of eradication treatment in HCWcf. RESULTS:A higher proportion of HCWcf acquired MRSA [n = 10/21] compared to non-HCWcf [n = 40/255] (P <0.001). The odds of MRSA acquisition were 8.4 (95 % CI, 3.0 - 23.4) times greater in HCWcf than non-HCWcf. HCWcf with MRSA were older (P = 0.02) and had better lung function (P = 0.009), yet hospitalisation rates were similar compared to non-HCWcf with MRSA. Chronic MRSA infection developed in 36/50 CF patients (HCWcf, n = 6; non-HCWcf, n = 30), with eradication therapy achieved in 5/6 (83 %) HCWcf. CONCLUSIONS:The rate of MRSA incidence was highest in HCWcf and the workplace is a possible source of acquisition. Vocational guidance should include the potential for MRSA acquisition for CF patients considering healthcare professions.
journal_name
BMC Pulm Medjournal_title
BMC pulmonary medicineauthors
Wood ME,Sherrard LJ,Ramsay KA,Yerkovich ST,Reid DW,Kidd TJ,Bell SCdoi
10.1186/s12890-016-0243-zsubject
Has Abstractpub_date
2016-05-11 00:00:00pages
78issue
1issn
1471-2466pii
10.1186/s12890-016-0243-zjournal_volume
16pub_type
杂志文章abstract:BACKGROUND:Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of phospholipoproteinaceous material in the alveoli. The presentation is nonspecific but typically includes dyspnea; the spectrum of disease includes rapidly progressive hypoxic respiratory failure. Whole lung lavage (W...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-019-0822-x
更新日期:2019-03-12 00:00:00
abstract:BACKGROUND:Scleromyxedema is a progressive, systemic connective tissue disorder characterized by fibro-mucous skin lesions and increased serum monoclonal immunoglobulin levels. Pulmonary involvement occurs in a subset of patients, though the overall prevalence of pulmonary lesions in scleromyxedema is unknown. Since pu...
journal_title:BMC pulmonary medicine
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abstract:BACKGROUND:Compared to other pulmonary function tests, there is a lack of standardization regarding how a maximum voluntary ventilation (MVV) maneuver is performed. Specifically, little is known about the variation in breathing frequency (fR) and its potential impact on the accuracy of test results. This study examines...
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doi:10.1186/s12890-018-0650-4
更新日期:2018-05-24 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-12-27
更新日期:2012-06-22 00:00:00
abstract::Following publication of the original article [1], the author flagged aspects of the article that affected readability of some of the article's scientific content. ...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,已发布勘误
doi:10.1186/s12890-018-0717-2
更新日期:2018-11-07 00:00:00
abstract:BACKGROUND:Asthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized control trial (RCT) is to evaluate short-term (end of rehabilitation) and intermediate-term effectiveness ...
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pub_type: 杂志文章,随机对照试验
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更新日期:2017-03-09 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12890-015-0022-2
更新日期:2015-03-25 00:00:00
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pub_type: 杂志文章
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更新日期:2020-04-20 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,多中心研究
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更新日期:2017-12-02 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-14-130
更新日期:2014-08-07 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-018-0725-2
更新日期:2018-10-30 00:00:00
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doi:10.1186/s12890-015-0066-3
更新日期:2015-07-10 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12890-015-0144-6
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:The use of extracorporeal membrane oxygenation (ECMO) in awake, spontaneously breathing and non-intubated patients (awake ECMO) may be a novel therapeutic strategy for severe acute respiratory distress syndrome (ARDS) patients. The purpose of this study is to assess the feasibility and safety of awake ECMO i...
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pub_type: 杂志文章
doi:10.1186/s12890-019-1016-2
更新日期:2019-12-09 00:00:00
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pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12890-016-0315-0
更新日期:2016-11-24 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2466-14-73
更新日期:2014-04-29 00:00:00
abstract:BACKGROUND:Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, however, is still a matter of debate. METHODS:In this study, we searched the PubMed, EmBase, and Coch...
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pub_type: 杂志文章,meta分析
doi:10.1186/s12890-017-0541-0
更新日期:2017-12-12 00:00:00
abstract::Following publication of the original article [1], the authors flagged that the article had published with an error in 'Table 1'. ...
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pub_type: 杂志文章,已发布勘误
doi:10.1186/s12890-020-1051-z
更新日期:2020-01-21 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12890-017-0526-z
更新日期:2017-12-04 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1186/s12890-019-0852-4
更新日期:2019-05-21 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2466-8-5
更新日期:2008-02-28 00:00:00
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pub_type: 杂志文章
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更新日期:2018-03-27 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-12-75
更新日期:2012-12-11 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12890-018-0666-9
更新日期:2018-08-13 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12890-019-1039-8
更新日期:2019-12-30 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2466-13-49
更新日期:2013-08-05 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2013-06-10 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2015-04-30 00:00:00
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pub_type: 杂志文章,评审
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