Antibiotics for treatment of acute exacerbation of chronic obstructive pulmonary disease: a network meta-analysis.

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities. The main causes of COPD are Gene-environment interactions associated with tobacco smoking (COPD-TS) and biomass smoke (COPD-BS). It is w...

journal_title：BMC pulmonary medicine

authors： Velasco-Torres Y,Ruiz-López V,Pérez-Bautista O,Buendía-Roldan I,Ramírez-Venegas A,Pérez-Ramos J,Falfán-Valencia R,Ramos C,Montaño M

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Late-onset noninfectious pulmonary complications (LONIPCs), which occur more than 3 months after allogeneic hematopoietic stem cell transplantation (HSCT), are major causes of morbidity and mortality after transplantation. Among LONIPCs, we occasionally treat patients with late-onset severe restrictive lung ...

journal_title：BMC pulmonary medicine

authors： Namkoong H,Ishii M,Mori T,Sugiura H,Tasaka S,Sakurai M,Koda Y,Kato J,Hasegawa N,Okamoto S,Betsuyaku T

更新日期：2017-09-07 00:00:00

abstract：BACKGROUND:In Europe, administration of an inhaled corticosteroid (ICS) combined with a long-acting β2 agonist is approved in chronic obstructive pulmonary disease (COPD) patients with a pre-bronchodilator FEV1 < 60% predicted normal, a history of repeated exacerbations, and who have significant symptoms despite regula...

journal_title：BMC pulmonary medicine

authors： Roche N,Pribil C,Van Ganse E,Serrier P,Housset B,Poirier D,Texier N,Schück S,Boucot I

更新日期：2014-04-02 00:00:00

abstract：BACKGROUND:Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machinery and epithelial barrier integrity genes. We used a targeted gene expression arrays to identify cha...

journal_title：BMC pulmonary medicine

authors： Pascoe CD,Obeidat M,Arsenault BA,Nie Y,Warner S,Stefanowicz D,Wadsworth SJ,Hirota JA,Jasemine Yang S,Dorscheid DR,Carlsten C,Hackett TL,Seow CY,Paré PD

更新日期：2017-12-11 00:00:00

abstract：BACKGROUND:The long-term prognosis of chronic cough and its determinants need to be clarified. METHODS:This is a prospective, observational cohort study. Eighty-nine unselected subjects with chronic (> 8 weeks' duration) cough were carefully investigated: Clinical examination, symptom questionnaire, Leicester Cough Qu...

journal_title：BMC pulmonary medicine

authors： Koskela HO,Lätti AM,Purokivi MK

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:Despite advances in asthma treatment, severe asthma (SA) still results in high morbidity and use of health resources. Our hypothesis was that SA patients would achieve adequate control with a systematic protocol, including oral corticosteroids, budesonide/formoterol maintenance and reliever therapy and a mul...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Carvalho-Pinto R,Fernandes FL,Rached S,Rabe K,Cukier A,Stelmach R

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:The effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study was to investigate whether a novel, community-based exercise program (CBE) was feasible and effective for pat...

journal_title：BMC pulmonary medicine

authors： Amin S,Abrazado M,Quinn M,Storer TW,Tseng CH,Cooper CB

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:Zosteriform skin metastasis (ZSM) is rare, and its etiology is not well understood. ZSM is possibly derived from the retrograde movement of cancer cells through the lymphatic vessels during disease development. However, it has been difficult to demonstrate it, as no specific findings have been observed. CAS...

journal_title：BMC pulmonary medicine

authors： Maki Y,Kimizuka Y,Murakami K,Sato K,Sasaki H,Yamamoto T,Watanabe C,Sano T,Miyata J,Fujikura Y,Kawana A

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:The early diagnosis of non-small cell lung cancer is of great significance to the prognosis of patients. However, traditional histopathology and imaging screening have certain limitations. Therefore, new diagnostical methods are urgently needed for the current clinical diagnosis. In this study we evaluated t...

journal_title：BMC pulmonary medicine

authors： Li J,Liao Y,Ran Y,Wang G,Wu W,Qiu Y,Liu J,Wen N,Jing T,Wang H,Zhang S

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:The breakdown of alveolar barrier dysfunction contributes to Lipopolysaccharide stimulated pulmonary edema and acute lung injury. Actin cytoskeleton has been implicated to be critical in regulation of epithelial barrier. Here, we performed in vivo and in vitro study to investigate role of TLR4-p38 MAPK-Hsp27...

journal_title：BMC pulmonary medicine

authors： Wang W,Weng J,Yu L,Huang Q,Jiang Y,Guo X

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Neurohumoral activation is present in COPD and might provide a link between pulmonary and systemic effects, especially cardiovascular disease. Because long acting inhaled β-agonists reduce hyperinflation, they could reduce sympathoexcitation by improving the inflation reflex. We aimed to evaluate if inhaled ...

journal_title：BMC pulmonary medicine

authors： Haarmann H,Mohrlang C,Tschiesner U,Rubin DB,Bornemann T,Rüter K,Bonev S,Raupach T,Hasenfuß G,Andreas S

更新日期：2015-04-30 00:00:00

abstract：BACKGROUND:Omega-3 fatty acids, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and derivatives, play a key role in the resolution of inflammation. Higher intake has been linked to decreased morbidity in several diseases, though effects on respiratory diseases like COPD are...

journal_title：BMC pulmonary medicine

authors： Lemoine S CM,Brigham EP,Woo H,Hanson CK,McCormack MC,Koch A,Putcha N,Hansel NN

更新日期：2019-05-21 00:00:00

abstract：BACKGROUND:The ability to objectively differentiate exacerbations of chronic obstructive pulmonary disease (COPD) from day-to-day symptom variations would be an important development in clinical practice and research. We assessed the ability of domiciliary pulse oximetry to achieve this. METHODS:40 patients with moder...

journal_title：BMC pulmonary medicine

authors： Hurst JR,Donaldson GC,Quint JK,Goldring JJ,Patel AR,Wedzicha JA

更新日期：2010-10-20 00:00:00

abstract：BACKGROUND:Cystic Fibrosis (CF) is a hereditary pulmonary and extra-pulmonary disease that occurs equally in men and women. However, a difference in morbidity and mortality rates between the sexes has been long documented. Similarly, a sex-disparity in disease severity has been reported in asthma as well. Studies done ...

journal_title：BMC pulmonary medicine

authors： Lam GY,Goodwin J,Wilcox P,Quon BS

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:People with cystic fibrosis (CF) may work in healthcare settings risking nosocomial pathogen acquisition. The aim of this study was to determine the incidence of methicillin-resistant Staphylococcus aureus (MRSA) infection in adult healthcare workers with CF (HCWcf). METHODS:Data was collected in this obser...

journal_title：BMC pulmonary medicine

authors： Wood ME,Sherrard LJ,Ramsay KA,Yerkovich ST,Reid DW,Kidd TJ,Bell SC

更新日期：2016-05-11 00:00:00

abstract：BACKGROUND:Pulmonary surfactant D (SP-D) has important regulatory functions for innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary disease (COPD). We hypothesized that COPD patients would have reduced bronchoalveolar lavage (BAL) fluid SP-D levels compared to healthy smoking and no...

journal_title：BMC pulmonary medicine

authors： Moré JM,Voelker DR,Silveira LJ,Edwards MG,Chan ED,Bowler RP

更新日期：2010-10-25 00:00:00

abstract：BACKGROUND:Despite optimal pharmacological therapy and pulmonary rehabilitation, patients with COPD continue to be breathless. There is a need to develop additional strategies to alleviate symptoms. Learning to sing requires control of breathing and posture and might have benefits that translate into daily life. METHO...

journal_title：BMC pulmonary medicine

authors： Lord VM,Cave P,Hume VJ,Flude EJ,Evans A,Kelly JL,Polkey MI,Hopkinson NS

更新日期：2010-08-03 00:00:00

abstract：BACKGROUND:Physical training has been shown to improve exercise capabilities in patients with asthma. Most studies focused on children and younger adults. Previously, the maximum program duration was six months. It is not known whether the same results may be obtained with lower intensity programs and sustained for tim...

journal_title：BMC pulmonary medicine

authors： Meyer A,Günther S,Volmer T,Taube K,Baumann HJ

更新日期：2015-05-07 00:00:00

abstract：BACKGROUND:CHCHD2 was identified a novel cell migration-promoting gene, which could promote cell migration and altered cell adhesion when ectopically overexpressed in NIH3T3 fibroblasts, and it was identified as a protein necessary for OxPhos function as well. However, the clinic relevance of CHCHD2 expression in NSCLC...

journal_title：BMC pulmonary medicine

authors： Yin X,Xia J,Sun Y,Zhang Z

更新日期：2020-02-13 00:00:00

abstract：BACKGROUND:A variety of large randomized controlled trials (RCT's) evaluating pharmacotherapy in chronic obstructive pulmonary disease (COPD) patients does exist. One of the drugs that has been tested is the new long-acting anticholinergic glycopyrronium bromide. METHODS:As the generalizability of results from RCT's i...

journal_title：BMC pulmonary medicine

authors： Kardos P,Vogelmeier C,Buhl R,Criée CP,Worth H

更新日期：2015-01-12 00:00:00

abstract：BACKGROUND:Malignant pleural mesothelioma (MPM) is marked by its difficult diagnosis and poor prognosis. Medical thoracoscopy (MT) is an effective and safe procedure for the diagnosis of exudative pleural effusions and many factors associated with poor prognosis of MPM. We conducted this study to investigate the value ...

journal_title：BMC pulmonary medicine

authors： Xu LL,Yang Y,Wang Z,Wang XJ,Tong ZH,Shi HZ

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:Although cigarette smoking may have a negative impact on the clinical outcome of pulmonary tuberculosis (PTB), few studies have investigated the impact of smoking-associated lung diseases. Emphysema is a major pathological finding of smoking-related lung damage. We aimed to clarify the effect of emphysema on...

journal_title：BMC pulmonary medicine

authors： Takasaka N,Seki Y,Fujisaki I,Uchiyama S,Matsubayashi S,Sato A,Yamanaka Y,Odashima K,Kazuyori T,Seki A,Takeda H,Ishikawa T,Kuwano K

更新日期：2020-11-07 00:00:00

abstract：BACKGROUND:Mechanical ventilation (MV), compared to spontaneous breathing (SB), has been found to increase abdominal edema and inflammation in experimental sepsis. Our hypothesis was that in primary acute respiratory distress syndrome (ARDS) MV would enhance inflammation and edema in the abdomen. METHODS:Thirteen pigl...

journal_title：BMC pulmonary medicine

authors： Marchesi S,Hedenstierna G,Hata A,Feinstein R,Larsson A,Larsson AO,Lipcsey M

更新日期：2020-04-25 00:00:00

abstract：BACKGROUND:Hypoxemia is a major complication of COPD and is a strong predictor of mortality. We previously identified independent risk factors for the presence of resting hypoxemia in the COPDGene cohort. However, little is known about characteristics that predict onset of resting hypoxemia in patients who are normoxic...

journal_title：BMC pulmonary medicine

authors： Wells JM,Estepar RS,McDonald MN,Bhatt SP,Diaz AA,Bailey WC,Jacobson FL,Dransfield MT,Washko GR,Make BJ,Casaburi R,van Beek EJ,Hoffman EA,Sciurba FC,Crapo JD,Silverman EK,Hersh CP,COPDGene Investigators.

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The dysfunction of airway epithelial barrier is closely related to the pathogenesis of asthma. Secreted Hsp90α participates in inflammation and Hsp90 inhibitor protects endothelial dysfunction. In the current study, we aimed to explore the role of secreted Hsp90α in asthmatic airway epithelial barrier functi...

journal_title：BMC pulmonary medicine

authors： Ye C,Huang C,Zou M,Hu Y,Luo L,Wei Y,Wan X,Zhao H,Li W,Cai S,Dong H

更新日期：2019-11-20 00:00:00

abstract：BACKGROUND:ALK-rearrangement is observed in < 5% non-small cell lung cancer (NSCLC) cases and prior to the advent of oral tyrosine kinase inhibitors, the natural history of oncogenic NSCLC was typically poor. Literature relating to regression of treatment-naïve NSCLC is limited, and regression without treatment has not...

journal_title：BMC pulmonary medicine

authors： Walls M,Walls GM,James JA,Crawford KT,Abdulkhalek H,Lynch TB,Peace AJ,McManus TE,Evans OR

更新日期：2020-08-06 00:00:00

abstract：BACKGROUND:Irisin, a recently discovered myokine, is assumed to be secreted by muscle cells in response to exercise and is involved in the regulation of energy metabolism by browning white adipose tissue cells. However, due to the fact that previous studies revealed conflicting results concerning the association betwee...

journal_title：BMC pulmonary medicine

authors： Kerstholt N,Ewert R,Nauck M,Spielhagen T,Bollmann T,Stubbe B,Felix SB,Wallaschofski H,Gläser S,Friedrich N

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:To compare the microbiological culture within endotracheal aspirate specimens (ETAs) and endotracheal tube specimens (ETTs) in patients undergoing mechanical ventilation (MV) by statistical tools. METHOD:ETAs and ETTs from a total number of 81 patients, who were undergoing MV at the intensive care unit (ICU...

journal_title：BMC pulmonary medicine

authors： Shen L,Wang F,Shi J,Xu W,Jiang T,Tang H,Yu X,Yin H,Hu S,Wu X,Chan SK,Sun J,Chang Q

更新日期：2019-08-27 00:00:00

abstract：BACKGROUND:Physical and psychological symptoms are the hallmark of patients' subjective perception of their illness. The purpose of this analysis was to determine if patients with COPD have distinctive symptom profiles and to examine the association of symptom profiles with systemic biomarkers of inflammation. METHODS...

journal_title：BMC pulmonary medicine

authors： Nguyen HQ,Herting JR,Pike KC,Gharib SA,Matute-Bello G,Borson S,Kohen R,Adams SG,Fan VS

更新日期：2016-12-03 00:00:00

abstract：BACKGROUND:Interleukin (IL)-3 amplifies inflammation. However, the effect of IL-3 in acute lung injury (ALI), an acute inflammatory disease, is unclear. The aim of this study was to test the hypothesis that IL-3 plays an important role in hyperoxia-induced ALI. METHODS:Hyperoxic ALI was induced in wild-type (WT) and I...

journal_title：BMC pulmonary medicine

authors： Huang Z,Zhang W,Yang J,Sun F,Zhou H

更新日期：2018-10-30 00:00:00