Worsening pulmonary outcomes during sex reassignment therapy in a transgender female with cystic fibrosis (CF) and asthma/allergic bronchopulmonary aspergillosis: a case report.

abstract：BACKGROUND:The tracheobronchomalacia is a life-threatening complication of mucopolysaccharidosis (MPS) without known effective, optimal treatment. The severe expiratory collapse of the trachea and bronchi is one of causes of the high rate of deaths in the course of airway impairment in MPSII patients. CASE PRESENTATIO...

journal_title：BMC pulmonary medicine

authors： Gocyk W,Warmus J,Olechnowicz H,Bik-Multanowski M,Pawlinski L,Kiec-Wilk B

更新日期：2020-04-20 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：BMC pulmonary medicine

authors： Pakhale S,Armstrong M,Holly C,Edjoc R,Gaudet E,Aaron S,Tasca G,Cameron W,Balfour L

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a rare disease characterized by proliferation and occlusion of small pulmonary arterioles, which has been associated with a high mortality rate. The pathogenesis of PH is complex and incompletely understood, which includes both genetic and environmental factors that alter vascu...

journal_title：BMC pulmonary medicine

authors： Yin C,Li K,Yu Y,Huang H,Yu Y,Wang Z,Yan J,Pu Y,Li Z,Li D,Chen P,Chen F

更新日期：2018-10-05 00:00:00

abstract：BACKGROUND:During the pathological destruction of lung tissue, neutrophil elastase (NE) degrades elastin, one of the major constituents of lung parenchyma. However there are no non-invasive methods to quantify NE degradation of elastin. We selected specific elastin fragments generated by NE for antibody generation and ...

journal_title：BMC pulmonary medicine

authors： Kristensen JH,Karsdal MA,Sand JM,Willumsen N,Diefenbach C,Svensson B,Hägglund P,Oersnes-Leeming DJ

更新日期：2015-05-03 00:00:00

abstract：BACKGROUND:Appropriate sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitore...

journal_title：BMC pulmonary medicine

authors： Hsu CW,Sun SF,Chu KA,Lee DL,Wong KF

更新日期：2014-02-06 00:00:00

abstract：BACKGROUND:The FACED score is an easy-to-use multidimensional grading system that has demonstrated an excellent prognostic value for mortality in patients with bronchiectasis. A Spanish group developed the score but no multicenter international validation has yet been published. METHODS:Retrospective and multicenter s...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Pereira MC,Gramblicka G,Cavalcanti-Lundgren F,de Figueiredo MF,Arancibia F,Rached S,de la Rosa D,Máiz-Carro L,Girón R,Olveira C,Prados C,Martinez-Garcia MA

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:Anti-tuberculosis therapy requires at least six-month treatment with continuous administration of combined antibiotics, including isoniazid, rifampicin, pyrazinamide, and ethambutol. The long-term exposure to antibiotics could cause consequent changes in gut microbiota, which may alter the gastrointestinal f...

journal_title：BMC pulmonary medicine

authors： Shi W,Hu Y,Zheng X,Ning Z,Wu M,Xia F,Prast-Nielsen S,Hu YOO,Xu B

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and the Medical Outcomes Study Short Form 36 (SF-36) are widely used to assess patient-reported outcome in individuals with pulmonary hypertension (PH). The aim of the study was to compare the psychometric properties of the two measures. METHODS:...

journal_title：BMC pulmonary medicine

authors： Twiss J,McKenna S,Ganderton L,Jenkins S,Ben-L'amri M,Gain K,Fowler R,Gabbay E

更新日期：2013-07-12 00:00:00

abstract：BACKGROUND:We have previously shown that diabetic rats are more susceptible to sepsis, but that the Acute lung injury (ALI) secondary to sepsis is less intense than in non-diabetics. In the present study, we further investigated the ALI-secondary to sepsis in diabetic rats and the effect of insulin treatment. METHODS:...

journal_title：BMC pulmonary medicine

authors： Filgueiras LR,Capelozzi VL,Martins JO,Jancar S

更新日期：2014-11-15 00:00:00

abstract：BACKGROUND:As supra-physiological intake of corticosteroids is a well known risk factor for the development of adrenal insufficiency, we investigated the function of the hypothalamic-pituitary-adrenal (HPA) axis during a 14-day course of systemic corticosteroids in patients with acute exacerbation of chronic obstructiv...

journal_title：BMC pulmonary medicine

authors： Schuetz P,Christ-Crain M,Schild U,Süess E,Facompre M,Baty F,Nusbaumer C,Brutsche M,Müller B

更新日期：2008-01-26 00:00:00

abstract：BACKGROUND:The tissue factor (TF)-dependent extrinsic pathway has been suggested to be a central mechanism by which the coagulation cascade is locally activated in the lungs of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) and thus represents an attractive target for therapeutic int...

journal_title：BMC pulmonary medicine

authors： Morris PE,Steingrub JS,Huang BY,Tang S,Liu PM,Rhode PR,Wong HC

更新日期：2012-02-16 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is hallmarked by inflammatory processes and a progressive decline of lung function. YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown. ...

journal_title：BMC pulmonary medicine

authors： Holmgaard DB,Mygind LH,Titlestad IL,Madsen H,Pedersen SS,Johansen JS,Pedersen C

更新日期：2013-12-30 00:00:00

abstract：BACKGROUND:Very few data exist on the management of community-acquired pneumonia (CAP) in patients admitted to hospitals in the Gulf region. The objectives of this study were to describe treatment patterns for CAP in 38 hospitals in five Gulf countries (United Arab Emirates, Kuwait, Bahrain, Oman, and Qatar) and to com...

journal_title：BMC pulmonary medicine

authors： Mahboub B,Al Zaabi A,Al Ali OM,Ahmed R,Niederman MS,El-Bishbishi R

更新日期：2015-09-30 00:00:00

abstract：BACKGROUND:Scleromyxedema is a progressive, systemic connective tissue disorder characterized by fibro-mucous skin lesions and increased serum monoclonal immunoglobulin levels. Pulmonary involvement occurs in a subset of patients, though the overall prevalence of pulmonary lesions in scleromyxedema is unknown. Since pu...

journal_title：BMC pulmonary medicine

authors： Kreidy M,Al-Hilli A,Yachoui R,Resnick J

更新日期：2020-01-09 00:00:00

abstract：BACKGROUND:During the past decades, numerous efforts have been made to decrease the death rate among lung cancer patients. Nonetheless, the improvement in long-term survival has been limited and lung cancer is still a devastating disease. DISCUSSION:With this article we would like to point out that survival of lung ca...

journal_title：BMC pulmonary medicine

authors： Heuvers ME,Hegmans JP,Stricker BH,Aerts JG

更新日期：2012-12-13 00:00:00

abstract：BACKGROUND:US mentholated cigarette sales have increased considerably over 50 years. Preference for mentholated cigarettes is markedly higher in Black people. While menthol itself is not genotoxic or carcinogenic, its acute respiratory effects might affect inhalation of cigarette smoke. This possibility seems consisten...

journal_title：BMC pulmonary medicine

authors： Lee PN

更新日期：2011-04-18 00:00:00

abstract：BACKGROUND:Late-onset noninfectious pulmonary complications (LONIPCs), which occur more than 3 months after allogeneic hematopoietic stem cell transplantation (HSCT), are major causes of morbidity and mortality after transplantation. Among LONIPCs, we occasionally treat patients with late-onset severe restrictive lung ...

journal_title：BMC pulmonary medicine

authors： Namkoong H,Ishii M,Mori T,Sugiura H,Tasaka S,Sakurai M,Koda Y,Kato J,Hasegawa N,Okamoto S,Betsuyaku T

更新日期：2017-09-07 00:00:00

abstract：BACKGROUND:The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management. Our aim was to compare real life operational characteristics for three EGFR mutation assays - two targeted approaches ...

journal_title：BMC pulmonary medicine

authors： Cernomaz AT,Macovei II,Pavel I,Grigoriu C,Marinca M,Baty F,Peter S,Zonda R,Brutsche M,Grigoriu B

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:The importance of the lung parenchyma in the pathophysiology of asthma has previously been demonstrated. Considering that nitric oxide synthases (NOS) and arginases compete for the same substrate, it is worthwhile to elucidate the effects of complex NOS-arginase dysfunction in the pathophysiology of asthma, ...

journal_title：BMC pulmonary medicine

authors： Aristoteles LR,Righetti RF,Pinheiro NM,Franco RB,Starling CM,da Silva JC,Pigati PA,Caperuto LC,Prado CM,Dolhnikoff M,Martins MA,Leick EA,Tibério IF

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a distinct form of interstitial pneumonia with unknown origin and poor prognosis. Current pharmacologic treatments are limited and lung transplantation is a viable option for appropriate patients. The aim of this review was to summarize lung transplantation survival in ...

journal_title：BMC pulmonary medicine

authors： Kistler KD,Nalysnyk L,Rotella P,Esser D

更新日期：2014-08-16 00:00:00

abstract：BACKGROUND:Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, however, is still a matter of debate. METHODS:In this study, we searched the PubMed, EmBase, and Coch...

journal_title：BMC pulmonary medicine

authors： Zhang HL,Tan M,Qiu AM,Tao Z,Wang CH

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:Asthma is a chronic inflammatory airway disease characterized by reversible obstruction, inflammation and hyperresponsiveness to different stimulus. Aerobic and breathing exercises have been demonstrated to benefit asthmatic patients; however, there is no evidence comparing the effectiveness of these treatme...

journal_title：BMC pulmonary medicine

authors： Evaristo KB,Saccomani MG,Martins MA,Cukier A,Stelmach R,Rodrigues MR,Santaella DF,Carvalho CR

更新日期：2014-10-17 00:00:00

abstract：BACKGROUND:Clinical guidelines specify that diagnosis of interstitial pulmonary fibrosis (IPF) requires identification of usual interstitial pneumonia (UIP) pattern. While UIP can be identified by high resolution CT of the chest, the results are often inconclusive, making surgical lung biopsy necessary to reach a defin...

journal_title：BMC pulmonary medicine

authors： Choi Y,Lu J,Hu Z,Pankratz DG,Jiang H,Cao M,Marchisano C,Huiras J,Fedorowicz G,Wong MG,Anderson JR,Tom EY,Babiarz J,Imtiaz U,Barth NM,Walsh PS,Kennedy GC,Huang J

更新日期：2017-11-17 00:00:00

abstract：BACKGROUND:Although many studies on people with Chronic Obstructive Pulmonary Disease (COPD) have examined the mutual impact of physical status and emotional experience, there is limited knowledge about the way COPD people first-hand perceive their condition. This study was designed to investigate the illness perceptio...

journal_title：BMC pulmonary medicine

authors： Pozzar M,Volpato E,Valota C,Pagnini F,Banfi PI

更新日期：2020-05-04 00:00:00

abstract：BACKGROUND:Community-acquired pneumonia (CAP) requires urgent and specific antimicrobial therapy. However, the causal pathogen is typically unknown at the point when anti-infective therapeutics must be initiated. Physicians synthesize information from diverse data streams to make appropriate decisions. Artificial intel...

journal_title：BMC pulmonary medicine

authors： Lhommet C,Garot D,Grammatico-Guillon L,Jourdannaud C,Asfar P,Faisy C,Muller G,Barker KA,Mercier E,Robert S,Lanotte P,Goudeau A,Blasco H,Guillon A

更新日期：2020-03-06 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic reached Europe in early 2020. Convalescent plasma is used without a consistent evidence of efficacy. Our hypothesis is that passive immunization with plasma collected from patients having contracted COVID-19 and developed specific neutralizing antibodies may alleviate symptoms and reduc...

journal_title：BMC pulmonary medicine

authors： Misset B,Hoste E,Donneau AF,Grimaldi D,Meyfroidt G,Moutschen M,Compernolle V,Gothot A,Desmecht D,Garigliany M,Najdovski T,Laterre PF

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:There are not enough data on the epidemiology of asthma in the Kingdom of Saudi Arabia (KSA). We analyzed data from a national household survey conducted in KSA in 2013 to estimate prevalence, associated risk factors and control measurements of asthma. METHODS:The Saudi Health Interview Survey was a cross-s...

journal_title：BMC pulmonary medicine

authors： Moradi-Lakeh M,El Bcheraoui C,Daoud F,Tuffaha M,Kravitz H,Al Saeedi M,Basulaiman M,Memish ZA,AlMazroa MA,Al Rabeeah AA,Mokdad AH

更新日期：2015-07-28 00:00:00

abstract：BACKGROUND:Dose intensity and dose density of first line Platinum and Etoposide (PE) do not influence Overall Survival (OS) of Small Cell Lung Cancer (SCLC) patients. The effect of treatment length, however, remains unclear. Current guidelines recommend treating beyond 4 cycles -up to 6-, in patients that respond to an...

journal_title：BMC pulmonary medicine

authors： Sallam M,Wong H,Escriu C

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Subcutaneous treprostinil is a prostacyclin analogue used to treat pulmonary arterial hypertension (PAH). Due to local pain it can cause a deterioration of heart related quality of life (HRQoL) or even abandonment of treatment. The aim of this paper was to assess the feasibility of treatment with intravenous...

journal_title：BMC pulmonary medicine

authors： Kurzyna M,Małaczyńska-Rajpold K,Koteja A,Pawlak A,Chrzanowski Ł,Furdal M,Gąsior Z,Jacheć W,Sobkowicz B,Norwa J,Mularek-Kubzdela T,Torbicki A

更新日期：2017-12-02 00:00:00

abstract：BACKGROUND:Epithelial-mesenchymal transition (EMT) has been believed to be related with chemotherapy resistance in non-small cell lung cancer (NSCLC). Recent studies have suggested eIF5A-2 may function as a proliferation-related oncogene in tumorigenic processes. METHODS:We used cell viability assays, western blotting...

journal_title：BMC pulmonary medicine

authors： Xu G,Yu H,Shi X,Sun L,Zhou Q,Zheng D,Shi H,Li N,Zhang X,Shao G

更新日期：2014-11-07 00:00:00