Reference values for the 6-minute walk test in healthy children and adolescents in Switzerland.

Abstract:

BACKGROUND:The six-minute walk test (6MWT) is a simple, low tech, safe and well established, self-paced assessment tool to quantify functional exercise capacity in adults. The definition of normal 6MWT in children is especially demanding since not only parameters like height, weight and ethnical background influence the measurement, but may be as crucial as age and the developmental stage. The aim of this study is establishing reference values for the 6MWT in healthy children and adolescents in Switzerland and to investigate the influence of age, anthropometrics, heart rate, blood pressure and physical activity on the distance walked. METHODS:Children and adolescents between 5-17 years performed a 6MWT. Short questionnaire assessments about their health state and physical activities. anthropometrics and vitals were measured before and after a 6-minute walk test and were previously defined as secondary outcomes. RESULTS:Age, height, weight and the heart rate after the 6MWT all predicted the distance walked according to different regression models: age was the best single predictor and mostly influenced walk distance in younger age, anthropometrics were more important in adolescents and females. Heart rate after the 6MWT was an important distance predictor in addition to age and outreached anthropometrics in the majority of subgroups assessed. CONCLUSIONS:The 6MWT in children and adolescents is feasible and practical. The 6MWT distance depends mainly on age; however, heart rate after the 6MWT, height and weight significantly add information and should be taken into account mainly in adolescents. Reference equations allow predicting 6-minute walk test distance and may help to better assess and compare outcomes in young patients with cardiovascular and respiratory diseases and are highly warranted for different populations.

journal_name

BMC Pulm Med

journal_title

BMC pulmonary medicine

authors

Ulrich S,Hildenbrand FF,Treder U,Fischler M,Keusch S,Speich R,Fasnacht M

doi

10.1186/1471-2466-13-49

subject

Has Abstract

pub_date

2013-08-05 00:00:00

pages

49

issn

1471-2466

pii

1471-2466-13-49

journal_volume

13

pub_type

杂志文章
  • Do-not-resuscitate orders in patients with community-acquired pneumonia: a retrospective study.

    abstract:BACKGROUND:To investigate the use of do-not-resuscitate (DNR) orders in patients hospitalized with community-acquired pneumonia (CAP) and the association with mortality. METHODS:We assembled a cohort of 1317 adults hospitalized with radiographically confirmed CAP in three Danish hospitals. Patients were grouped into n...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-020-01236-1

    authors: Egelund GB,Jensen AV,Petersen PT,Andersen SB,Lindhardt BØ,Rohde G,Ravn P,von Plessen C

    更新日期:2020-07-24 00:00:00

  • Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma.

    abstract:BACKGROUND:Interleukin-9 (IL-9)-targeted therapies may offer a novel approach for treating asthmatics. Two randomized placebo-controlled studies were conducted to assess the safety profile and potential efficacy of multiple subcutaneous doses of MEDI-528, a humanized anti-IL-9 monoclonal antibody, in asthmatics. METHO...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2466-11-14

    authors: Parker JM,Oh CK,LaForce C,Miller SD,Pearlman DS,Le C,Robbie GJ,White WI,White B,Molfino NA,MEDI-528 Clinical Trials Group.

    更新日期:2011-02-28 00:00:00

  • Interleukin-3 plays a vital role in hyperoxic acute lung injury in mice via mediating inflammation.

    abstract:BACKGROUND:Interleukin (IL)-3 amplifies inflammation. However, the effect of IL-3 in acute lung injury (ALI), an acute inflammatory disease, is unclear. The aim of this study was to test the hypothesis that IL-3 plays an important role in hyperoxia-induced ALI. METHODS:Hyperoxic ALI was induced in wild-type (WT) and I...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-018-0725-2

    authors: Huang Z,Zhang W,Yang J,Sun F,Zhou H

    更新日期:2018-10-30 00:00:00

  • Role of TLR4-p38 MAPK-Hsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability.

    abstract:BACKGROUND:The breakdown of alveolar barrier dysfunction contributes to Lipopolysaccharide stimulated pulmonary edema and acute lung injury. Actin cytoskeleton has been implicated to be critical in regulation of epithelial barrier. Here, we performed in vivo and in vitro study to investigate role of TLR4-p38 MAPK-Hsp27...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-018-0735-0

    authors: Wang W,Weng J,Yu L,Huang Q,Jiang Y,Guo X

    更新日期:2018-11-27 00:00:00

  • Psychometric performance of the CAMPHOR and SF-36 in pulmonary hypertension.

    abstract:BACKGROUND:The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and the Medical Outcomes Study Short Form 36 (SF-36) are widely used to assess patient-reported outcome in individuals with pulmonary hypertension (PH). The aim of the study was to compare the psychometric properties of the two measures. METHODS:...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2466-13-45

    authors: Twiss J,McKenna S,Ganderton L,Jenkins S,Ben-L'amri M,Gain K,Fowler R,Gabbay E

    更新日期:2013-07-12 00:00:00

  • Circulating tumor cells prior to initial treatment is an important prognostic factor of survival in non-small cell lung cancer: a meta-analysis and system review.

    abstract:BACKGROUND:Our study aimed to verify the prognostic value of circulating tumor cells (CTCs) prior to initial treatment on survival of non-small cell lung cancer (NSCLC) by using meta-analysis and system review of published studies. MATERIALS AND METHODS:The PubMed, EMBASE and Cochrane Library were searched, respective...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12890-019-1029-x

    authors: Jiang SS,Deng B,Feng YG,Qian K,Tan QY,Wang RW

    更新日期:2019-12-26 00:00:00

  • Radiation-induced lung injury: current evidence.

    abstract::Chemo-radiotherapy and systemic therapies have proven satisfactory outcomes as standard treatments for various thoracic malignancies; however, adverse pulmonary effects, like pneumonitis, can be life-threatening. Pneumonitis is caused by direct cytotoxic effect, oxidative stress, and immune-mediated injury. Radiothera...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1186/s12890-020-01376-4

    authors: Arroyo-Hernández M,Maldonado F,Lozano-Ruiz F,Muñoz-Montaño W,Nuñez-Baez M,Arrieta O

    更新日期:2021-01-06 00:00:00

  • Real-life use of fluticasone propionate/salmeterol in patients with chronic obstructive pulmonary disease: a French observational study.

    abstract:BACKGROUND:In Europe, administration of an inhaled corticosteroid (ICS) combined with a long-acting β2 agonist is approved in chronic obstructive pulmonary disease (COPD) patients with a pre-bronchodilator FEV1 < 60% predicted normal, a history of repeated exacerbations, and who have significant symptoms despite regula...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/1471-2466-14-56

    authors: Roche N,Pribil C,Van Ganse E,Serrier P,Housset B,Poirier D,Texier N,Schück S,Boucot I

    更新日期:2014-04-02 00:00:00

  • Combined effects of leaks, respiratory system properties and upper airway patency on the performance of home ventilators: a bench study.

    abstract:BACKGROUND:Combined effects of leaks, mechanical property of respiratory system and upper airway (UA) patency on patient-ventilator synchrony (PVA) and the level of clinically "tolerable" leaks are not well established in home ventilators. METHODS:We comparatively assessed on a bench model, the highest leak level tole...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-017-0487-2

    authors: Zhu K,Rabec C,Gonzalez-Bermejo J,Hardy S,Aouf S,Escourrou P,Roisman G

    更新日期:2017-11-21 00:00:00

  • Assessment of the alveolar volume when sampling exhaled gas at different expired volumes in the single breath diffusion test.

    abstract:BACKGROUND:Alveolar volume measured according to the American Thoracic Society-European Respiratory Society (ATS-ERS) guidelines during the single breath diffusion test can be underestimated when there is maldistribution of ventilation. Therefore, the alveolar volume calculated by taking into account the ATS-ERS guidel...

    journal_title:BMC pulmonary medicine

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-2466-7-18

    authors: Prediletto R,Fornai E,Catapano G,Carli C

    更新日期:2007-12-19 00:00:00

  • Bilirubin as a prognostic marker in patients with pulmonary arterial hypertension.

    abstract:BACKGROUND:Liver dysfunction reflects the status of heart failure, with congestion and low perfusion of the liver serving as causative mechanisms. Previous studies demonstrated relationship between the results of liver function test and the prognosis in patients with heart failure. However, few studies have examined th...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/1471-2466-10-22

    authors: Takeda Y,Takeda Y,Tomimoto S,Tani T,Narita H,Kimura G

    更新日期:2010-04-22 00:00:00

  • Predicting the microbial cause of community-acquired pneumonia: can physicians or a data-driven method differentiate viral from bacterial pneumonia at patient presentation?

    abstract:BACKGROUND:Community-acquired pneumonia (CAP) requires urgent and specific antimicrobial therapy. However, the causal pathogen is typically unknown at the point when anti-infective therapeutics must be initiated. Physicians synthesize information from diverse data streams to make appropriate decisions. Artificial intel...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-020-1089-y

    authors: Lhommet C,Garot D,Grammatico-Guillon L,Jourdannaud C,Asfar P,Faisy C,Muller G,Barker KA,Mercier E,Robert S,Lanotte P,Goudeau A,Blasco H,Guillon A

    更新日期:2020-03-06 00:00:00

  • Survival of bronchiectatic patients with respiratory failure in ICU.

    abstract:BACKGROUND:The outcome of patients with bronchiectasis during and after their stay in the intensive care unit (ICU) has seldom been reported in the literature. Managing these patients in the ICU can be challenging because of the complex nature of their disease. This study aims to identify the in-hospital and long-term ...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/1471-2466-7-17

    authors: Alzeer AH,Masood M,Basha SJ,Shaik SA

    更新日期:2007-12-10 00:00:00

  • Real-world treatment patterns for patients 80 years and older with early lung cancer: a nationwide claims study.

    abstract:BACKGROUND:Old age is an important factor that could affect the treatment of early-stage lung cancer. In this study, we evaluated the treatment patterns and outcomes of patients over the age of 80 years who had been diagnosed with early-stage lung cancer in real-world practice. METHODS:Elderly patients who were diagno...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-018-0699-0

    authors: Lee K,Kim HO,Choi HK,Seo GH

    更新日期:2018-08-03 00:00:00

  • A controlled study of community-based exercise training in patients with moderate COPD.

    abstract:BACKGROUND:The effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study was to investigate whether a novel, community-based exercise program (CBE) was feasible and effective for pat...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2466-14-125

    authors: Amin S,Abrazado M,Quinn M,Storer TW,Tseng CH,Cooper CB

    更新日期:2014-08-04 00:00:00

  • A 12-month, moderate-intensity exercise training program improves fitness and quality of life in adults with asthma: a controlled trial.

    abstract:BACKGROUND:Physical training has been shown to improve exercise capabilities in patients with asthma. Most studies focused on children and younger adults. Previously, the maximum program duration was six months. It is not known whether the same results may be obtained with lower intensity programs and sustained for tim...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-015-0053-8

    authors: Meyer A,Günther S,Volmer T,Taube K,Baumann HJ

    更新日期:2015-05-07 00:00:00

  • A prospective study of salvational intervention with ICS/LABA for reducing chronic obstructive pulmonary disease exacerbation under severe air pollution (SIRCAP) in Beijing: protocol of a multi-center randomized controlled trial.

    abstract:BACKGROUND:Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality all over the world. Acute exacerbation of COPD (AECOPD) not only accelerates the progression of disease, but also causes hospital administration and death events. Epidemiologic studies have shown air pollution is a high ...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-018-0771-9

    authors: Zhou T,Zhong Y,Liao J,Wang G,Li X,Qian X,Xiang P,Chen X,Xu Z,Zhang F,Wang X,Wang S,Li X,Yu C,Zhang Y,Xia G,Dai L

    更新日期:2019-01-25 00:00:00

  • Performance of noninvasive ventilation in acute respiratory failure in critically ill patients: a prospective, observational, cohort study.

    abstract:BACKGROUND:Noninvasive ventilation (NIV) is used in critically ill patients with acute respiratory failure (ARF) to avoid endotracheal intubation. However, the impact of NIV use on ARF patient's outcomes is still unclear. Our objectives were to evaluate the rate of NIV failure in hypoxemic patients with an arterial car...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-015-0139-3

    authors: Corrêa TD,Sanches PR,de Morais LC,Scarin FC,Silva E,Barbas CS

    更新日期:2015-11-11 00:00:00

  • Asthma out of control? A structured review of recent patient surveys.

    abstract:BACKGROUND:An understanding of the needs and behaviors of asthma patients is important in developing an asthma-related healthcare policy. The primary goal of the present review was to assess patient perspectives on key issues in asthma and its management, as captured in patient surveys. METHODS:Local, national, and mu...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/1471-2466-6-S1-S2

    authors: Holgate ST,Price D,Valovirta E

    更新日期:2006-11-30 00:00:00

  • Radiological pleuroparenchymal fibroelastosis associated to limited cutaneous systemic sclerosis: a case report.

    abstract:BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a very rare interstitial lung disease (ILD) characterized by progressive fibrotic lesions of the visceral pleura and the sub-pleural parenchyma, affecting predominantly the upper lobes. PPFE may occur in different contextes like bone marrow or lung transplantations,...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-018-0641-5

    authors: Hassoun D,Dirou S,Arrigoni PP,Durant C,Hamidou M,Néel A,Agard C

    更新日期:2018-05-18 00:00:00

  • Comparison of next generation sequencing, SNaPshot assay and real-time polymerase chain reaction for lung adenocarcinoma EGFR mutation assessment.

    abstract:BACKGROUND:The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management. Our aim was to compare real life operational characteristics for three EGFR mutation assays - two targeted approaches ...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-016-0250-0

    authors: Cernomaz AT,Macovei II,Pavel I,Grigoriu C,Marinca M,Baty F,Peter S,Zonda R,Brutsche M,Grigoriu B

    更新日期:2016-05-23 00:00:00

  • Case report of endoprosthesis -Y implantation in severe respiratory failure in the MPSII patient; comparison with literature data.

    abstract:BACKGROUND:The tracheobronchomalacia is a life-threatening complication of mucopolysaccharidosis (MPS) without known effective, optimal treatment. The severe expiratory collapse of the trachea and bronchi is one of causes of the high rate of deaths in the course of airway impairment in MPSII patients. CASE PRESENTATIO...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-020-1143-9

    authors: Gocyk W,Warmus J,Olechnowicz H,Bik-Multanowski M,Pawlinski L,Kiec-Wilk B

    更新日期:2020-04-20 00:00:00

  • Physical activity and sedentary time are related to clinically relevant health outcomes among adults with obstructive lung disease.

    abstract:BACKGROUND:The purpose of the current study was to determine the association between sedentary time and physical activity with clinically relevant health outcomes among adults with impaired spirometry and those with or without self-reported obstructive lung disease (asthma or COPD). METHODS:Data from participants of t...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-018-0659-8

    authors: Dogra S,Good J,Buman MP,Gardiner PA,Copeland JL,Stickland MK

    更新日期:2018-06-07 00:00:00

  • Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease.

    abstract:BACKGROUND:As supra-physiological intake of corticosteroids is a well known risk factor for the development of adrenal insufficiency, we investigated the function of the hypothalamic-pituitary-adrenal (HPA) axis during a 14-day course of systemic corticosteroids in patients with acute exacerbation of chronic obstructiv...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/1471-2466-8-1

    authors: Schuetz P,Christ-Crain M,Schild U,Süess E,Facompre M,Baty F,Nusbaumer C,Brutsche M,Müller B

    更新日期:2008-01-26 00:00:00

  • Latin America validation of FACED score in patients with bronchiectasis: an analysis of six cohorts.

    abstract:BACKGROUND:The FACED score is an easy-to-use multidimensional grading system that has demonstrated an excellent prognostic value for mortality in patients with bronchiectasis. A Spanish group developed the score but no multicenter international validation has yet been published. METHODS:Retrospective and multicenter s...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12890-017-0417-3

    authors: Athanazio R,Pereira MC,Gramblicka G,Cavalcanti-Lundgren F,de Figueiredo MF,Arancibia F,Rached S,de la Rosa D,Máiz-Carro L,Girón R,Olveira C,Prados C,Martinez-Garcia MA

    更新日期:2017-04-26 00:00:00

  • Prevalence and etiologies of pulmonary hypertension in Africa: a systematic review and meta-analysis.

    abstract:BACKGROUND:Despite the recent increasing worldwide attention towards pulmonary hypertension (PH), its epidemiology remains poorly described in Africa. Accordingly, we performed a systematic review and meta-analysis of PH prevalence, incidence and etiologies in Africa. METHODS:We searched PubMed, EMBASE, African Journa...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/s12890-017-0549-5

    authors: Bigna JJ,Noubiap JJ,Nansseu JR,Aminde LN

    更新日期:2017-12-08 00:00:00

  • Correction to: Severe but not moderate hyperoxia of newborn mice causes an emphysematous lung phenotype in adulthood without persisting oxidative stress and inflammation.

    abstract::Following publication of the original article [1], the authors flagged that the article had published with an error in 'Table 1'. ...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,已发布勘误

    doi:10.1186/s12890-020-1051-z

    authors: Kindermann A,Binder L,Baier J,Gündel B,Simm A,Haase R,Bartling B

    更新日期:2020-01-21 00:00:00

  • Birt-Hogg-Dubé syndrome: a literature review and case study of a Chinese woman presenting a novel FLCN mutation.

    abstract:BACKGROUND:The Birt-Hogg-Dubé (BHD) syndrome is a very rare autosomal dominant form of genodermatosis caused by germline mutations in the folliculin (FLCN) gene, which is mapped to the p11.2 region in chromosome 17. BHD commonly presents cutaneous fibrofolliculomas, pulmonary cysts, renal cell carcinoma, and recurrent ...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章,评审

    doi:10.1186/s12890-017-0383-9

    authors: Hao S,Long F,Sun F,Liu T,Li D,Jiang S

    更新日期:2017-02-21 00:00:00

  • Microbiological analysis of endotracheal aspirate and endotracheal tube cultures in mechanically ventilated patients.

    abstract:BACKGROUND:To compare the microbiological culture within endotracheal aspirate specimens (ETAs) and endotracheal tube specimens (ETTs) in patients undergoing mechanical ventilation (MV) by statistical tools. METHOD:ETAs and ETTs from a total number of 81 patients, who were undergoing MV at the intensive care unit (ICU...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/s12890-019-0926-3

    authors: Shen L,Wang F,Shi J,Xu W,Jiang T,Tang H,Yu X,Yin H,Hu S,Wu X,Chan SK,Sun J,Chang Q

    更新日期:2019-08-27 00:00:00

  • Asthma control in patients receiving inhaled corticosteroid and long-acting beta2-agonist fixed combinations. A real-life study comparing dry powder inhalers and a pressurized metered dose inhaler extrafine formulation.

    abstract:BACKGROUND:Although patients have more problems using metered dose inhalers, clinical comparisons suggest they provide similar control to dry powder inhalers. Using real-life situations this study was designed to evaluate asthma control in outpatients with moderate to severe persistent asthma and to compare efficacy of...

    journal_title:BMC pulmonary medicine

    pub_type: 杂志文章

    doi:10.1186/1471-2466-11-40

    authors: Müller V,Gálffy G,Eszes N,Losonczy G,Bizzi A,Nicolini G,Chrystyn H,Tamási L

    更新日期:2011-07-15 00:00:00