Abstract:
BACKGROUND:The outcome of patients with bronchiectasis during and after their stay in the intensive care unit (ICU) has seldom been reported in the literature. Managing these patients in the ICU can be challenging because of the complex nature of their disease. This study aims to identify the in-hospital and long-term outcome of patients with bronchiectasis and respiratory failure (RF) in ICU. METHODS:A retrospective study was carried out by studying all bronchiectatic patients admitted to the medical ICU for RF over a 10-year period (1995-2004). RESULTS:The mean (+/- standard deviation) age of 35 patients was 63.5 +/- 11.7 years and APACHE score was 22.3 +/- 7.3. The 4-year mortality was 60%. Among the variables observed, age > 65 years (hazard ratio (HR): 4.15; 95% confidence interval (CI): 3.2-5.1), APACHE II score > 24 (2.6, 95% CI 1.7-3.5), intubation (2.81, 95 %CI 1.9-3.7), inotropic support (2.9, 95% CI 2.0-3.7), Home-O2 (4.0, 95% CI 2.7-5.2) and activity index (4.0, 95% CI 2.8-5.3) were associated with diminished survival in univariate analysis by Cox regression. By long rank test, survival probabilities were significantly low at these strata. Multivariate analysis of Cox proportional hazard model showed that age > 65 years (HR: 5.4, 95% CI 1.9-15.7); activity index (HR: 4.8, 95% CI 1.4-16.6); and inotropic support (HR: 3.8, 95% CI 1.5-10.1) were independently associated with reduced survival. CONCLUSION:The decreased survival of ICU patients was associated with age > 65 years, activity index (bedridden or wheelchair-bound) and use of inotropic support.
journal_name
BMC Pulm Medjournal_title
BMC pulmonary medicineauthors
Alzeer AH,Masood M,Basha SJ,Shaik SAdoi
10.1186/1471-2466-7-17subject
Has Abstractpub_date
2007-12-10 00:00:00pages
17issn
1471-2466pii
1471-2466-7-17journal_volume
7pub_type
杂志文章abstract:BACKGROUND:As supra-physiological intake of corticosteroids is a well known risk factor for the development of adrenal insufficiency, we investigated the function of the hypothalamic-pituitary-adrenal (HPA) axis during a 14-day course of systemic corticosteroids in patients with acute exacerbation of chronic obstructiv...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-8-1
更新日期:2008-01-26 00:00:00
abstract:BACKGROUND:Plasma levels of cell-free DNA (cf-DNA) are known to be elevated in sepsis and high levels are associated with a poor prognosis. Mechanical ventilation affects systemic inflammation in which lung-protective ventilation attenuates the inflammatory response. The aim was to study the effect of a lung protective...
journal_title:BMC pulmonary medicine
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doi:10.1186/s12890-020-1175-1
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-01356-8
更新日期:2020-12-09 00:00:00
abstract:BACKGROUND:Pseudomonas aeruginosa infections are associated with progressive life threatening decline of lung function in cystic fibrosis sufferers. Growth of Ps. aeruginosa releases a "grape-like" odour that has been identified as the microbial volatile organic compound 2-aminoacetophenone (2-AA). METHODS:We investig...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-10-56
更新日期:2010-11-07 00:00:00
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doi:10.1186/s12890-019-0784-z
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abstract:BACKGROUND:Asthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized control trial (RCT) is to evaluate short-term (end of rehabilitation) and intermediate-term effectiveness ...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12890-017-0389-3
更新日期:2017-03-09 00:00:00
abstract:BACKGROUND:Although patients have more problems using metered dose inhalers, clinical comparisons suggest they provide similar control to dry powder inhalers. Using real-life situations this study was designed to evaluate asthma control in outpatients with moderate to severe persistent asthma and to compare efficacy of...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-11-40
更新日期:2011-07-15 00:00:00
abstract:BACKGROUND:The incidence and prevalence of chronic kidney disease (CKD) continue to rise worldwide. Increasing age, diabetes, hypertension, and cigarette smoking are well-recognized risk factors for CKD. Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation leading to airway obstr...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,meta分析,评审
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,meta分析
doi:10.1186/s12890-019-0990-8
更新日期:2019-12-18 00:00:00
abstract:BACKGROUND:Pulmonary sequestration (PS) is a form of congenital pulmonary malformation that is generally diagnosed in childhood or adolescence and usually resected when diagnosed. We aim to identify the clinical presentation and course of patients diagnosed to have PS during adulthood. METHODS:Using a computer-assiste...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-018-0663-z
更新日期:2018-06-05 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2466-14-169
更新日期:2014-11-01 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-017-0544-x
更新日期:2017-12-13 00:00:00
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abstract:BACKGROUND:The early diagnosis of non-small cell lung cancer is of great significance to the prognosis of patients. However, traditional histopathology and imaging screening have certain limitations. Therefore, new diagnostical methods are urgently needed for the current clinical diagnosis. In this study we evaluated t...
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pub_type: 杂志文章
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1186/1471-2466-6-S1-S2
更新日期:2006-11-30 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-018-0641-5
更新日期:2018-05-18 00:00:00
abstract:BACKGROUND:Bronchiectasis is characterized by abnormal, permanent and irreversible dilatation of the bronchi, usually responsible for daily symptoms and frequent respiratory complications. Many causes have been identified, but only limited data are available concerning the association between bronchiectasis and renal t...
journal_title:BMC pulmonary medicine
pub_type: 杂志文章,多中心研究
doi:10.1186/s12890-015-0133-9
更新日期:2015-11-07 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/1471-2466-14-56
更新日期:2014-04-02 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,多中心研究
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,meta分析,评审
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更新日期:2014-04-15 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,评审
doi:10.1186/s12890-017-0564-6
更新日期:2017-12-28 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,已发布勘误
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更新日期:2020-01-21 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2466-13-45
更新日期:2013-07-12 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-017-0496-1
更新日期:2017-11-21 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章,随机对照试验
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更新日期:2014-07-28 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12890-019-0852-4
更新日期:2019-05-21 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-1128-8
更新日期:2020-04-15 00:00:00
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journal_title:BMC pulmonary medicine
pub_type: 杂志文章
doi:10.1186/s12890-020-1057-6
更新日期:2020-01-30 00:00:00