Cigarette and IL-17A synergistically induce bronchial epithelial-mesenchymal transition via activating IL-17R/NF-κB signaling.

abstract：BACKGROUND:Penicillium species are among the most common fungi present in the environment and are usually considered non-pathogenic to humans. However, in immunocompromised hosts they can be virulent pathogens and can cause death. Penicillium digitatum is a plant pathogen that commonly causes a postharvest fungal disea...

journal_title：BMC pulmonary medicine

authors： Oshikata C,Tsurikisawa N,Saito A,Watanabe M,Kamata Y,Tanaka M,Tsuburai T,Mitomi H,Takatori K,Yasueda H,Akiyama K

更新日期：2013-03-23 00:00:00

abstract：BACKGROUND:Reduced lung function in patients with chronic obstructive pulmonary disease (COPD) is likely due to both environmental and genetic factors. We report here a targeted high-throughput DNA sequencing approach to identify new and previously known genetic variants in a set of candidate genes for COPD. METHODS:E...

journal_title：BMC pulmonary medicine

authors： Matsson H,Söderhäll C,Einarsdottir E,Lamontagne M,Gudmundsson S,Backman H,Lindberg A,Rönmark E,Kere J,Sin D,Postma DS,Bossé Y,Lundbäck B,Klar J

更新日期：2016-11-11 00:00:00

abstract：BACKGROUND:The Darlington and Northallerton Asthma Study is an observational cohort study started in 1983. At that time little was published about long term outcome in asthma and the contribution of change in reversible disease or airway remodelling to any excess deterioration in function. The study design included reg...

journal_title：BMC pulmonary medicine

authors： Connolly CK,Prescott RJ

更新日期：2005-01-31 00:00:00

abstract：BACKGROUND:Compared to other pulmonary function tests, there is a lack of standardization regarding how a maximum voluntary ventilation (MVV) maneuver is performed. Specifically, little is known about the variation in breathing frequency (fR) and its potential impact on the accuracy of test results. This study examines...

journal_title：BMC pulmonary medicine

authors： Neufeld EV,Dolezal BA,Speier W,Cooper CB

更新日期：2018-05-24 00:00:00

abstract：BACKGROUND:The collection of exhaled breath condensate (EBC) is a suitable and non-invasive method for evaluation of airway inflammation. Several studies indicate that the composition of the condensate and the recovery of biomarkers are affected by physical characteristics of the condensing device and collecting circum...

journal_title：BMC pulmonary medicine

authors： Hoffmeyer F,Raulf-Heimsoth M,Harth V,Bünger J,Brüning T

更新日期：2009-11-30 00:00:00

abstract：BACKGROUND:Zosteriform skin metastasis (ZSM) is rare, and its etiology is not well understood. ZSM is possibly derived from the retrograde movement of cancer cells through the lymphatic vessels during disease development. However, it has been difficult to demonstrate it, as no specific findings have been observed. CAS...

journal_title：BMC pulmonary medicine

authors： Maki Y,Kimizuka Y,Murakami K,Sato K,Sasaki H,Yamamoto T,Watanabe C,Sano T,Miyata J,Fujikura Y,Kawana A

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:Very few data exist on the management of community-acquired pneumonia (CAP) in patients admitted to hospitals in the Gulf region. The objectives of this study were to describe treatment patterns for CAP in 38 hospitals in five Gulf countries (United Arab Emirates, Kuwait, Bahrain, Oman, and Qatar) and to com...

journal_title：BMC pulmonary medicine

authors： Mahboub B,Al Zaabi A,Al Ali OM,Ahmed R,Niederman MS,El-Bishbishi R

更新日期：2015-09-30 00:00:00

abstract：BACKGROUND:Clinically hypomyopathic dermatomyositis is a rare disease that is important to recognize, investigate and treat early as it is associated with poor prognosis. In a proportion of patients, myositis specific antibodies could be negative, but with high clinical suspicion, myositis associated antibodies should ...

journal_title：BMC pulmonary medicine

authors： Alqatari S,Riddell P,Harney S,Henry M,Murphy G

更新日期：2018-04-17 00:00:00

abstract：BACKGROUND:Telehealth and telemonitoring is an emerging area of study in people with cystic fibrosis (CF), with the potential of increasing access to care, and minimising infection control risks to patients without compromising their health outcomes. To date, limited evidence is available to support the use of teleheal...

journal_title：BMC pulmonary medicine

authors： Lang RL,Wilson C,Stockton K,Russell T,Johnston LM

更新日期：2019-01-24 00:00:00

abstract：BACKGROUND:The accuracy of currently available same-day diagnostic tools (smear microscopy and conventional nucleic acid amplification tests) for pleural tuberculosis (TB) is sub-optimal. Newer technologies may offer improved detection. METHODS:Smear-microscopy, adenosine deaminase (ADA), interferon gamma (IFN-γ), and...

journal_title：BMC pulmonary medicine

authors： Meldau R,Peter J,Theron G,Calligaro G,Allwood B,Symons G,Khalfey H,Ntombenhle G,Govender U,Binder A,van Zyl-Smit R,Dheda K

更新日期：2014-04-08 00:00:00

abstract：BACKGROUND:This study is a cross sectional analysis, aiming to evaluate if atopy is as a risk factor for exercise induced bronchoconstriction (EIB) among Tunisian athletes. METHODS:Atopy was defined by a skin prick test result and EIB was defined as a decrease of at least 15% in forced expiratory volume in one second ...

journal_title：BMC pulmonary medicine

authors： Sallaoui R,Chamari K,Mossa A,Tabka Z,Chtara M,Feki Y,Amri M

更新日期：2009-02-05 00:00:00

abstract：BACKGROUND:Plasma levels of cell-free DNA (cf-DNA) are known to be elevated in sepsis and high levels are associated with a poor prognosis. Mechanical ventilation affects systemic inflammation in which lung-protective ventilation attenuates the inflammatory response. The aim was to study the effect of a lung protective...

journal_title：BMC pulmonary medicine

authors： Nyberg A,Larsson A,Jylhävä J,Hurme M,Sperber J,Lipcsey M,Castegren M

更新日期：2020-07-31 00:00:00

abstract：BACKGROUND:Technology offers opportunities to improve healthcare, but little is known about Internet use by COPD patients. We tested two hypotheses: Internet access is associated with socio-demographic disparities and frequency of use is related to perceived needs. METHODS:We analyzed data from a 2007-2008 national co...

journal_title：BMC pulmonary medicine

authors： Martinez CH,St Jean BL,Plauschinat CA,Rogers B,Beresford J,Martinez FJ,Richardson CR,Han MK

更新日期：2014-04-22 00:00:00

abstract：BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR) is a biomarker of inflammation in chronic obstructive pulmonary disease (COPD) patients. But, a meaningful threshold and the longitudinal changes are unknown. We aimed to investigate the association between NLR and the clinical characteristics of COPD patients and to dete...

journal_title：BMC pulmonary medicine

authors： Sakurai K,Chubachi S,Irie H,Tsutsumi A,Kameyama N,Kamatani T,Koh H,Terashima T,Nakamura H,Asano K,Betsuyaku T

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Scleromyxedema is a progressive, systemic connective tissue disorder characterized by fibro-mucous skin lesions and increased serum monoclonal immunoglobulin levels. Pulmonary involvement occurs in a subset of patients, though the overall prevalence of pulmonary lesions in scleromyxedema is unknown. Since pu...

journal_title：BMC pulmonary medicine

authors： Kreidy M,Al-Hilli A,Yachoui R,Resnick J

更新日期：2020-01-09 00:00:00

abstract：BACKGROUND:Hypoxemia is a major complication of COPD and is a strong predictor of mortality. We previously identified independent risk factors for the presence of resting hypoxemia in the COPDGene cohort. However, little is known about characteristics that predict onset of resting hypoxemia in patients who are normoxic...

journal_title：BMC pulmonary medicine

authors： Wells JM,Estepar RS,McDonald MN,Bhatt SP,Diaz AA,Bailey WC,Jacobson FL,Dransfield MT,Washko GR,Make BJ,Casaburi R,van Beek EJ,Hoffman EA,Sciurba FC,Crapo JD,Silverman EK,Hersh CP,COPDGene Investigators.

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:To investigate the use of do-not-resuscitate (DNR) orders in patients hospitalized with community-acquired pneumonia (CAP) and the association with mortality. METHODS:We assembled a cohort of 1317 adults hospitalized with radiographically confirmed CAP in three Danish hospitals. Patients were grouped into n...

journal_title：BMC pulmonary medicine

authors： Egelund GB,Jensen AV,Petersen PT,Andersen SB,Lindhardt BØ,Rohde G,Ravn P,von Plessen C

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:Our study aimed to verify the prognostic value of circulating tumor cells (CTCs) prior to initial treatment on survival of non-small cell lung cancer (NSCLC) by using meta-analysis and system review of published studies. MATERIALS AND METHODS:The PubMed, EMBASE and Cochrane Library were searched, respective...

journal_title：BMC pulmonary medicine

authors： Jiang SS,Deng B,Feng YG,Qian K,Tan QY,Wang RW

更新日期：2019-12-26 00:00:00

abstract：BACKGROUND:Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwide setting in patients with uncontrolled asthma. We defined uncontrolled asthma as a previous hospit...

journal_title：BMC pulmonary medicine

authors： Gullach AJ,Risgaard B,Lynge TH,Jabbari R,Glinge C,Haunsø S,Backer V,Winkel BG,Tfelt-Hansen J

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:Pulmonary surfactant D (SP-D) has important regulatory functions for innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary disease (COPD). We hypothesized that COPD patients would have reduced bronchoalveolar lavage (BAL) fluid SP-D levels compared to healthy smoking and no...

journal_title：BMC pulmonary medicine

authors： Moré JM,Voelker DR,Silveira LJ,Edwards MG,Chan ED,Bowler RP

更新日期：2010-10-25 00:00:00

abstract：BACKGROUND:COVID-19 is a systemic viral infection which mainly targets the human respiratory system with many secondary clinical manifestations especially affecting the hematopoietic system and haemostasis. Few studies have highlighted the prognostic value of blood findings such as lymphopenia, neutrophil/lymphocyte ra...

journal_title：BMC pulmonary medicine

authors： Lim AYH,Goh JL,Chua MCW,Heng BH,Abisheganaden JA,George PP

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:Pulmonary non-Hodgkin lymphoma (NHL) is rare. The most frequent subtype of pulmonary NHL is low-grade B-cell lymphoma, such as lymphoma of mucosa-associated lymphoma tissue. Extranodal natural killer cell/T-cell lymphoma, nasal type (ENKL) is characterized by predominant extranodal involvement and associatio...

journal_title：BMC pulmonary medicine

authors： Yabushita T,Yoshioka S,Furumiya T,Nakamura M,Yamashita D,Imai Y,Ishikawa T

更新日期：2019-02-21 00:00:00

abstract：BACKGROUND:Pulmonary rehabilitation offers potential benefits to people with asthma. It is however unknown if rehabilitation favourably affects patients' health care needs. We therefore examined if rehabilitation reduced needs and, in addition, if it improved asthma control. METHODS:One hundred fifty patients with ast...

journal_title：BMC pulmonary medicine

authors： Salandi J,Icks A,Gholami J,Hummel S,Schultz K,Apfelbacher C,Sheikh A,Loerbroks A

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Clinical guidelines specify that diagnosis of interstitial pulmonary fibrosis (IPF) requires identification of usual interstitial pneumonia (UIP) pattern. While UIP can be identified by high resolution CT of the chest, the results are often inconclusive, making surgical lung biopsy necessary to reach a defin...

journal_title：BMC pulmonary medicine

authors： Choi Y,Lu J,Hu Z,Pankratz DG,Jiang H,Cao M,Marchisano C,Huiras J,Fedorowicz G,Wong MG,Anderson JR,Tom EY,Babiarz J,Imtiaz U,Barth NM,Walsh PS,Kennedy GC,Huang J

更新日期：2017-11-17 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a rare disease characterized by proliferation and occlusion of small pulmonary arterioles, which has been associated with a high mortality rate. The pathogenesis of PH is complex and incompletely understood, which includes both genetic and environmental factors that alter vascu...

journal_title：BMC pulmonary medicine

authors： Yin C,Li K,Yu Y,Huang H,Yu Y,Wang Z,Yan J,Pu Y,Li Z,Li D,Chen P,Chen F

更新日期：2018-10-05 00:00:00

abstract：BACKGROUND:To evaluate the diagnostic accuracy of the integrated Practical Approach to Lung Health in South Africa (PALSA) guideline in identifying patients requiring bacteriological screening for tuberculosis (TB), and to determine which clinical features best predict suspected and bacteriologically-confirmed tubercul...

journal_title：BMC pulmonary medicine

authors： English RG,Bachmann MO,Bateman ED,Zwarenstein MF,Fairall LR,Bheekie A,Majara BP,Lombard C,Scherpbier R,Ottomani SE

更新日期：2006-08-25 00:00:00

abstract：BACKGROUND:Pulmonary sequestration (PS) is a form of congenital pulmonary malformation that is generally diagnosed in childhood or adolescence and usually resected when diagnosed. We aim to identify the clinical presentation and course of patients diagnosed to have PS during adulthood. METHODS:Using a computer-assiste...

journal_title：BMC pulmonary medicine

authors： Alsumrain M,Ryu JH

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection bias, and researchers should therefore always examine to what extent selection bias may be present in ...

journal_title：BMC pulmonary medicine

authors： Johannessen A,Verlato G,Benediktsdottir B,Forsberg B,Franklin K,Gislason T,Holm M,Janson C,Jögi R,Lindberg E,Macsali F,Omenaas E,Real FG,Saure EW,Schlünssen V,Sigsgaard T,Skorge TD,Svanes C,Torén K,Waatevik M,Nils

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:Despite advances in asthma treatment, severe asthma (SA) still results in high morbidity and use of health resources. Our hypothesis was that SA patients would achieve adequate control with a systematic protocol, including oral corticosteroids, budesonide/formoterol maintenance and reliever therapy and a mul...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Carvalho-Pinto R,Fernandes FL,Rached S,Rabe K,Cukier A,Stelmach R

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:Alveolar volume measured according to the American Thoracic Society-European Respiratory Society (ATS-ERS) guidelines during the single breath diffusion test can be underestimated when there is maldistribution of ventilation. Therefore, the alveolar volume calculated by taking into account the ATS-ERS guidel...

journal_title：BMC pulmonary medicine

authors： Prediletto R,Fornai E,Catapano G,Carli C

更新日期：2007-12-19 00:00:00