Circulating tumor cells prior to initial treatment is an important prognostic factor of survival in non-small cell lung cancer: a meta-analysis and system review.

abstract：BACKGROUND:The early diagnosis of non-small cell lung cancer is of great significance to the prognosis of patients. However, traditional histopathology and imaging screening have certain limitations. Therefore, new diagnostical methods are urgently needed for the current clinical diagnosis. In this study we evaluated t...

journal_title：BMC pulmonary medicine

authors： Li J,Liao Y,Ran Y,Wang G,Wu W,Qiu Y,Liu J,Wen N,Jing T,Wang H,Zhang S

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management. Our aim was to compare real life operational characteristics for three EGFR mutation assays - two targeted approaches ...

journal_title：BMC pulmonary medicine

authors： Cernomaz AT,Macovei II,Pavel I,Grigoriu C,Marinca M,Baty F,Peter S,Zonda R,Brutsche M,Grigoriu B

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:Plasma levels of cell-free DNA (cf-DNA) are known to be elevated in sepsis and high levels are associated with a poor prognosis. Mechanical ventilation affects systemic inflammation in which lung-protective ventilation attenuates the inflammatory response. The aim was to study the effect of a lung protective...

journal_title：BMC pulmonary medicine

authors： Nyberg A,Larsson A,Jylhävä J,Hurme M,Sperber J,Lipcsey M,Castegren M

更新日期：2020-07-31 00:00:00

abstract：BACKGROUND:The most prevalent complication of percutaneous lung biopsy is pneumothorax (PNX). A routine immediate post-procedure CT scan (ICT) to spot PNX is done in many centers. However, the diagnostic yield of this practice has not been studied broadly. We sought to evaluate whether an ICT could replace the routine ...

journal_title：BMC pulmonary medicine

authors： Brzezinski RY,Vigiser I,Fomin I,Israeli L,Shenhar-Tsarfaty S,Bar-Shai A

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:This study was conducted in order to determine the prevalence of asthma and associated risk factors in the adult population of Karachi, Pakistan. METHODS:This multi-stage, cross-sectional survey was conducted from May 2014-August 2015; comprising 1629 adults in 75 randomly selected clusters in Karachi, Paki...

journal_title：BMC pulmonary medicine

authors： Razzaq S,Nafees AA,Rabbani U,Irfan M,Naeem S,Khan MA,Fatmi Z,Burney P

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:The FACED score is an easy-to-use multidimensional grading system that has demonstrated an excellent prognostic value for mortality in patients with bronchiectasis. A Spanish group developed the score but no multicenter international validation has yet been published. METHODS:Retrospective and multicenter s...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Pereira MC,Gramblicka G,Cavalcanti-Lundgren F,de Figueiredo MF,Arancibia F,Rached S,de la Rosa D,Máiz-Carro L,Girón R,Olveira C,Prados C,Martinez-Garcia MA

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine the association between sedentary time and physical activity with clinically relevant health outcomes among adults with impaired spirometry and those with or without self-reported obstructive lung disease (asthma or COPD). METHODS:Data from participants of t...

journal_title：BMC pulmonary medicine

authors： Dogra S,Good J,Buman MP,Gardiner PA,Copeland JL,Stickland MK

更新日期：2018-06-07 00:00:00

abstract：BACKGROUND:The outcome of patients with bronchiectasis during and after their stay in the intensive care unit (ICU) has seldom been reported in the literature. Managing these patients in the ICU can be challenging because of the complex nature of their disease. This study aims to identify the in-hospital and long-term ...

journal_title：BMC pulmonary medicine

authors： Alzeer AH,Masood M,Basha SJ,Shaik SA

更新日期：2007-12-10 00:00:00

abstract：BACKGROUND:Pulmonary sequestration (PS) is a form of congenital pulmonary malformation that is generally diagnosed in childhood or adolescence and usually resected when diagnosed. We aim to identify the clinical presentation and course of patients diagnosed to have PS during adulthood. METHODS:Using a computer-assiste...

journal_title：BMC pulmonary medicine

authors： Alsumrain M,Ryu JH

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Pneumonia poses a significant burden to the U.S. health-care system. However, there are few data focusing on severe pneumonia, particularly cases of pneumonia associated with specialized care in intensive care units (ICU). METHODS:We used administrative and electronic medical record data from six integrated...

journal_title：BMC pulmonary medicine

authors： Storms AD,Chen J,Jackson LA,Nordin JD,Naleway AL,Glanz JM,Jacobsen SJ,Weintraub ES,Klein NP,Gargiullo PM,Fry AM

更新日期：2017-12-16 00:00:00

abstract：BACKGROUND:The breakdown of alveolar barrier dysfunction contributes to Lipopolysaccharide stimulated pulmonary edema and acute lung injury. Actin cytoskeleton has been implicated to be critical in regulation of epithelial barrier. Here, we performed in vivo and in vitro study to investigate role of TLR4-p38 MAPK-Hsp27...

journal_title：BMC pulmonary medicine

authors： Wang W,Weng J,Yu L,Huang Q,Jiang Y,Guo X

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:In bronchiectasis patients, chronic Pseudomonas aeruginosa (PA) infection has been associated with worse health-related quality of life (HRQL), but little is known about Mycobacterium avium complex lung disease (MACLD) patients in this context. This study aimed to evaluate HRQL and investigate the impact of ...

journal_title：BMC pulmonary medicine

authors： Kamata H,Asakura T,Suzuki S,Namkoong H,Yagi K,Funatsu Y,Okamori S,Uno S,Uwamino Y,Fujiwara H,Nishimura T,Ishii M,Betsuyaku T,Hasegawa N

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:Anemia is prevalent not only in COPD but also in pulmonary hypertension. We postulated that anemia may have certain prognostic value in COPD concomitant with PH due to COPD (COPD-PH). METHODS:We performed a 12-month prospective investigation to follow up COPD patients with or without PH assessed by right he...

journal_title：BMC pulmonary medicine

authors： Xiong W,Xu M,Pudasaini B,Guo X,Liu J

更新日期：2018-08-23 00:00:00

abstract：BACKGROUND:The pathological appearance of idiopathic pleuroparenchymal fibroelastosis (IPPFE) with hematoxylin-eosin staining is similar to that of usual interstitial pneumonia (UIP) in patients with idiopathic pulmonary fibrosis (IPF). The amount of elastic fibers (EF) and detailed differences between IPPFE and IPF ha...

journal_title：BMC pulmonary medicine

authors： Enomoto N,Kusagaya H,Oyama Y,Kono M,Kaida Y,Kuroishi S,Hashimoto D,Fujisawa T,Yokomura K,Inui N,Nakamura Y,Suda T

更新日期：2014-05-28 00:00:00

abstract：BACKGROUND:Many studies have investigated whether pleural cholesterol levels can aid in diagnosis of pleural exudates, and the results have varied considerably. To gain a more reliable answer to this question, we meta-analyzed the literature on using pleural cholesterol or the ratio of cholesterol in pleural fluid to c...

journal_title：BMC pulmonary medicine

authors： Shen Y,Zhu H,Wan C,Chen L,Wang T,Yang T,Wen F

更新日期：2014-04-15 00:00:00

abstract：BACKGROUND:YKL-40 is an extracellular matrix glycoprotein with a significant role in tissue inflammation and remodeling. MIP-1a has chemotactic and pro-inflammatory properties, and is induced by YKL-40 in several lung disorders. The aim of this study was to determine the levels of YKL-40 and MIP-1a in blood serum and p...

journal_title：BMC pulmonary medicine

authors： Adamidi T,Soulitzis N,Neofytou E,Zannetos S,Georgiou A,Benidis K,Papadopoulos A,Siafakas NM,Schiza SE

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Pulmonary surfactant D (SP-D) has important regulatory functions for innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary disease (COPD). We hypothesized that COPD patients would have reduced bronchoalveolar lavage (BAL) fluid SP-D levels compared to healthy smoking and no...

journal_title：BMC pulmonary medicine

authors： Moré JM,Voelker DR,Silveira LJ,Edwards MG,Chan ED,Bowler RP

更新日期：2010-10-25 00:00:00

abstract：BACKGROUND:Compared to other pulmonary function tests, there is a lack of standardization regarding how a maximum voluntary ventilation (MVV) maneuver is performed. Specifically, little is known about the variation in breathing frequency (fR) and its potential impact on the accuracy of test results. This study examines...

journal_title：BMC pulmonary medicine

authors： Neufeld EV,Dolezal BA,Speier W,Cooper CB

更新日期：2018-05-24 00:00:00

abstract：BACKGROUND:Abediterol is a novel, once-daily long-acting β2-agonist in development for the treatment of chronic obstructive pulmonary disease (COPD) and asthma in combination with an anti-inflammatory agent. This Phase IIa, randomised, double-blind, crossover study investigated the bronchodilation, safety, tolerability...

journal_title：BMC pulmonary medicine

authors： Beier J,Pujol H,Seoane B,Jimenez E,Astbury C,Massana E,Ruiz S,de Miquel G

更新日期：2016-07-20 00:00:00

abstract：BACKGROUND:Combined effects of leaks, mechanical property of respiratory system and upper airway (UA) patency on patient-ventilator synchrony (PVA) and the level of clinically "tolerable" leaks are not well established in home ventilators. METHODS:We comparatively assessed on a bench model, the highest leak level tole...

journal_title：BMC pulmonary medicine

authors： Zhu K,Rabec C,Gonzalez-Bermejo J,Hardy S,Aouf S,Escourrou P,Roisman G

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:Technology offers opportunities to improve healthcare, but little is known about Internet use by COPD patients. We tested two hypotheses: Internet access is associated with socio-demographic disparities and frequency of use is related to perceived needs. METHODS:We analyzed data from a 2007-2008 national co...

journal_title：BMC pulmonary medicine

authors： Martinez CH,St Jean BL,Plauschinat CA,Rogers B,Beresford J,Martinez FJ,Richardson CR,Han MK

更新日期：2014-04-22 00:00:00

abstract：BACKGROUND:Lower respiratory tract infection (LRIs) is very common both in terms of community-acquired infection and hospital-acquired infection. Sputum and bronchoalveolar lavage fluid (BALF) are the most important specimens obtained from patients with LRI. The choice of antibiotic with which to treat LRI usually depe...

journal_title：BMC pulmonary medicine

authors： Peng Z,Zhou J,Tian L

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, however, is still a matter of debate. METHODS:In this study, we searched the PubMed, EmBase, and Coch...

journal_title：BMC pulmonary medicine

authors： Zhang HL,Tan M,Qiu AM,Tao Z,Wang CH

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:The Birt-Hogg-Dubé (BHD) syndrome is a very rare autosomal dominant form of genodermatosis caused by germline mutations in the folliculin (FLCN) gene, which is mapped to the p11.2 region in chromosome 17. BHD commonly presents cutaneous fibrofolliculomas, pulmonary cysts, renal cell carcinoma, and recurrent ...

journal_title：BMC pulmonary medicine

authors： Hao S,Long F,Sun F,Liu T,Li D,Jiang S

更新日期：2017-02-21 00:00:00

abstract：BACKGROUND:The importance of the lung parenchyma in the pathophysiology of asthma has previously been demonstrated. Considering that nitric oxide synthases (NOS) and arginases compete for the same substrate, it is worthwhile to elucidate the effects of complex NOS-arginase dysfunction in the pathophysiology of asthma, ...

journal_title：BMC pulmonary medicine

authors： Aristoteles LR,Righetti RF,Pinheiro NM,Franco RB,Starling CM,da Silva JC,Pigati PA,Caperuto LC,Prado CM,Dolhnikoff M,Martins MA,Leick EA,Tibério IF

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the relationship between dynamic hyperinflation and daily physical activity (DPA) in adults with cystic fibrosis (CF). METHODS:Thirty-four clinically stable CF were studied. All patients undertook incremental cardiopulmonary exercise testing (CPET). CPET-related meas...

journal_title：BMC pulmonary medicine

authors： Savi D,Di Paolo M,Simmonds NJ,Pascucci C,Quattrucci S,Palange P

更新日期：2018-04-19 00:00:00

abstract：BACKGROUND:Exercise capacity is impaired in pulmonary arterial hypertension (PAH). We hypothesized that cardiovascular reserve abnormalities would be associated with impaired hemodynamic response to pharmacological stress and worse outcome in PAH. METHODS:Eighteen PAH patients (p) group 1 NYHA class II/III and ten con...

journal_title：BMC pulmonary medicine

authors： Domingo E,Grignola JC,Aguilar R,Arredondo C,Bouteldja N,Messeguer ML,Roman A

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:We have previously shown that diabetic rats are more susceptible to sepsis, but that the Acute lung injury (ALI) secondary to sepsis is less intense than in non-diabetics. In the present study, we further investigated the ALI-secondary to sepsis in diabetic rats and the effect of insulin treatment. METHODS:...

journal_title：BMC pulmonary medicine

authors： Filgueiras LR,Capelozzi VL,Martins JO,Jancar S

更新日期：2014-11-15 00:00:00

abstract：BACKGROUND:Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe hypersensitivity drug reaction involving the skin and multiple internal organ systems. The symptoms typically present with fever and skin rash, and rapidly progress to multiple organ failures. Vancomycin is a rare drug to cause DRESS s...

journal_title：BMC pulmonary medicine

authors： Wilcox O,Hassanein M,Armstrong J,Kassis N

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) with carbon dioxide retention is associated with a worsening clinical condition and the beginning of pulmonary ventilation decompensation. This study aimed to identify the factors associated with carbon dioxide retention. METHODS:This was a retrospective study of...

journal_title：BMC pulmonary medicine

authors： Wei X,Yu N,Ding Q,Ren J,Mi J,Bai L,Li J,Qi M,Guo Y

更新日期：2018-07-31 00:00:00