Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease.

abstract：BACKGROUND:CHCHD2 was identified a novel cell migration-promoting gene, which could promote cell migration and altered cell adhesion when ectopically overexpressed in NIH3T3 fibroblasts, and it was identified as a protein necessary for OxPhos function as well. However, the clinic relevance of CHCHD2 expression in NSCLC...

journal_title：BMC pulmonary medicine

authors： Yin X,Xia J,Sun Y,Zhang Z

更新日期：2020-02-13 00:00:00

abstract：BACKGROUND:Bronchiectasis is characterized by abnormal, permanent and irreversible dilatation of the bronchi, usually responsible for daily symptoms and frequent respiratory complications. Many causes have been identified, but only limited data are available concerning the association between bronchiectasis and renal t...

journal_title：BMC pulmonary medicine

authors： Dury S,Colosio C,Etienne I,Anglicheau D,Merieau E,Caillard S,Rivalan J,Thervet E,Essig M,Babinet F,Subra JF,Toubas O,Rieu P,Launois C,Perotin-Collard JM,Lebargy F,Deslée G,Spiesser group.

更新日期：2015-11-07 00:00:00

abstract：BACKGROUND:Aspergillus fumigatus is frequently encountered in sputum samples of patients with cystic fibrosis (CF), which traditionally has been interpreted as saprophytic airway colonization. However, this mere bystander role has been challenged by recent data. There is now evidence that Aspergillus fumigatus accelera...

journal_title：BMC pulmonary medicine

authors： Träger J,Melichar VO,Meyer R,Rauh M,Bogdan C,Held J

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Liver dysfunction reflects the status of heart failure, with congestion and low perfusion of the liver serving as causative mechanisms. Previous studies demonstrated relationship between the results of liver function test and the prognosis in patients with heart failure. However, few studies have examined th...

journal_title：BMC pulmonary medicine

authors： Takeda Y,Takeda Y,Tomimoto S,Tani T,Narita H,Kimura G

更新日期：2010-04-22 00:00:00

abstract：BACKGROUND:Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that would change with treatment in terms of exercise capacity or lung function...

journal_title：BMC pulmonary medicine

authors： Wark PAB,Cookson K,Thiruchelvam T,Brannan J,Dorahy DJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a distinct form of interstitial pneumonia with unknown origin and poor prognosis. Current pharmacologic treatments are limited and lung transplantation is a viable option for appropriate patients. The aim of this review was to summarize lung transplantation survival in ...

journal_title：BMC pulmonary medicine

authors： Kistler KD,Nalysnyk L,Rotella P,Esser D

更新日期：2014-08-16 00:00:00

abstract：BACKGROUND:Subcutaneous treprostinil is a prostacyclin analogue used to treat pulmonary arterial hypertension (PAH). Due to local pain it can cause a deterioration of heart related quality of life (HRQoL) or even abandonment of treatment. The aim of this paper was to assess the feasibility of treatment with intravenous...

journal_title：BMC pulmonary medicine

authors： Kurzyna M,Małaczyńska-Rajpold K,Koteja A,Pawlak A,Chrzanowski Ł,Furdal M,Gąsior Z,Jacheć W,Sobkowicz B,Norwa J,Mularek-Kubzdela T,Torbicki A

更新日期：2017-12-02 00:00:00

abstract：BACKGROUND:Pulmonary rehabilitation offers potential benefits to people with asthma. It is however unknown if rehabilitation favourably affects patients' health care needs. We therefore examined if rehabilitation reduced needs and, in addition, if it improved asthma control. METHODS:One hundred fifty patients with ast...

journal_title：BMC pulmonary medicine

authors： Salandi J,Icks A,Gholami J,Hummel S,Schultz K,Apfelbacher C,Sheikh A,Loerbroks A

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:An understanding of the needs and behaviors of asthma patients is important in developing an asthma-related healthcare policy. The primary goal of the present review was to assess patient perspectives on key issues in asthma and its management, as captured in patient surveys. METHODS:Local, national, and mu...

journal_title：BMC pulmonary medicine

authors： Holgate ST,Price D,Valovirta E

更新日期：2006-11-30 00:00:00

abstract：BACKGROUND:The accuracy of currently available same-day diagnostic tools (smear microscopy and conventional nucleic acid amplification tests) for pleural tuberculosis (TB) is sub-optimal. Newer technologies may offer improved detection. METHODS:Smear-microscopy, adenosine deaminase (ADA), interferon gamma (IFN-γ), and...

journal_title：BMC pulmonary medicine

authors： Meldau R,Peter J,Theron G,Calligaro G,Allwood B,Symons G,Khalfey H,Ntombenhle G,Govender U,Binder A,van Zyl-Smit R,Dheda K

更新日期：2014-04-08 00:00:00

abstract：BACKGROUND:Exercise capacity is impaired in pulmonary arterial hypertension (PAH). We hypothesized that cardiovascular reserve abnormalities would be associated with impaired hemodynamic response to pharmacological stress and worse outcome in PAH. METHODS:Eighteen PAH patients (p) group 1 NYHA class II/III and ten con...

journal_title：BMC pulmonary medicine

authors： Domingo E,Grignola JC,Aguilar R,Arredondo C,Bouteldja N,Messeguer ML,Roman A

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:With the goal of reducing exposure to secondhand smoke, the state of Minnesota (MN), enacted a smoke-free law (i.e., Freedom to Breathe Act) in all workplaces, restaurants, and bars in 2007. This retrospective cohort study analyzes emergency department (ED) visits in Olmsted County, MN, for chronic obstructi...

journal_title：BMC pulmonary medicine

authors： Croghan IT,Ebbert JO,Hays JT,Schroeder DR,Chamberlain AM,Roger VL,Hurt RD

更新日期：2015-01-22 00:00:00

abstract：BACKGROUND:YKL-40 is an extracellular matrix glycoprotein with a significant role in tissue inflammation and remodeling. MIP-1a has chemotactic and pro-inflammatory properties, and is induced by YKL-40 in several lung disorders. The aim of this study was to determine the levels of YKL-40 and MIP-1a in blood serum and p...

journal_title：BMC pulmonary medicine

authors： Adamidi T,Soulitzis N,Neofytou E,Zannetos S,Georgiou A,Benidis K,Papadopoulos A,Siafakas NM,Schiza SE

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Hyperoxia is common early in the course of resuscitation of critically ill patients. It has been associated with mortality in some, but not all, studies of cardiac arrest patients and other critically ill cohorts. Reasons for the inconsistency are unclear and may depend on unmeasured patient confounders, the...

journal_title：BMC pulmonary medicine

authors： Russell DW,Janz DR,Emerson WL,May AK,Bernard GR,Zhao Z,Koyama T,Ware LB

更新日期：2017-02-03 00:00:00

abstract：BACKGROUND:The most prevalent complication of percutaneous lung biopsy is pneumothorax (PNX). A routine immediate post-procedure CT scan (ICT) to spot PNX is done in many centers. However, the diagnostic yield of this practice has not been studied broadly. We sought to evaluate whether an ICT could replace the routine ...

journal_title：BMC pulmonary medicine

authors： Brzezinski RY,Vigiser I,Fomin I,Israeli L,Shenhar-Tsarfaty S,Bar-Shai A

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Telehealth and telemonitoring is an emerging area of study in people with cystic fibrosis (CF), with the potential of increasing access to care, and minimising infection control risks to patients without compromising their health outcomes. To date, limited evidence is available to support the use of teleheal...

journal_title：BMC pulmonary medicine

authors： Lang RL,Wilson C,Stockton K,Russell T,Johnston LM

更新日期：2019-01-24 00:00:00

abstract：BACKGROUND:Irisin, a recently discovered myokine, is assumed to be secreted by muscle cells in response to exercise and is involved in the regulation of energy metabolism by browning white adipose tissue cells. However, due to the fact that previous studies revealed conflicting results concerning the association betwee...

journal_title：BMC pulmonary medicine

authors： Kerstholt N,Ewert R,Nauck M,Spielhagen T,Bollmann T,Stubbe B,Felix SB,Wallaschofski H,Gläser S,Friedrich N

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:The assessment of airway inflammation for the diagnosis of asthma or COPD is still uncommon in pneumology-specialized general practices. In this respect, the measurement of exhaled nitric oxide (NO), as a fast and simple methodology, is increasingly used. The indirect assessment of airway inflammation, howev...

journal_title：BMC pulmonary medicine

authors： Holz O,Seiler T,Karmeier A,Fraedrich J,Leiner H,Magnussen H,Jörres RA,Welker L

更新日期：2008-02-28 00:00:00

abstract：BACKGROUND:The tracheobronchomalacia is a life-threatening complication of mucopolysaccharidosis (MPS) without known effective, optimal treatment. The severe expiratory collapse of the trachea and bronchi is one of causes of the high rate of deaths in the course of airway impairment in MPSII patients. CASE PRESENTATIO...

journal_title：BMC pulmonary medicine

authors： Gocyk W,Warmus J,Olechnowicz H,Bik-Multanowski M,Pawlinski L,Kiec-Wilk B

更新日期：2020-04-20 00:00:00

abstract：BACKGROUND:Neurohumoral activation is present in COPD and might provide a link between pulmonary and systemic effects, especially cardiovascular disease. Because long acting inhaled β-agonists reduce hyperinflation, they could reduce sympathoexcitation by improving the inflation reflex. We aimed to evaluate if inhaled ...

journal_title：BMC pulmonary medicine

authors： Haarmann H,Mohrlang C,Tschiesner U,Rubin DB,Bornemann T,Rüter K,Bonev S,Raupach T,Hasenfuß G,Andreas S

更新日期：2015-04-30 00:00:00

abstract：BACKGROUND:In adults, overweight is associated with reduced lung function, in children evidence on this association is conflicting. We examined the association of body mass index (BMI) and waist circumference (WC) at age 12, and of persistently (at ages 8 and 12 years) high BMI and large WC, with forced vital capacity ...

journal_title：BMC pulmonary medicine

authors： Bekkers MB,Wijga AH,Gehring U,Koppelman GH,de Jongste JC,Smit HA,Brunekreef B

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:Pleuroparenchymal fibroelastosis (PPFE) is a very rare interstitial lung disease (ILD) characterized by progressive fibrotic lesions of the visceral pleura and the sub-pleural parenchyma, affecting predominantly the upper lobes. PPFE may occur in different contextes like bone marrow or lung transplantations,...

journal_title：BMC pulmonary medicine

authors： Hassoun D,Dirou S,Arrigoni PP,Durant C,Hamidou M,Néel A,Agard C

更新日期：2018-05-18 00:00:00

abstract：BACKGROUND:Although cigarette smoking may have a negative impact on the clinical outcome of pulmonary tuberculosis (PTB), few studies have investigated the impact of smoking-associated lung diseases. Emphysema is a major pathological finding of smoking-related lung damage. We aimed to clarify the effect of emphysema on...

journal_title：BMC pulmonary medicine

authors： Takasaka N,Seki Y,Fujisaki I,Uchiyama S,Matsubayashi S,Sato A,Yamanaka Y,Odashima K,Kazuyori T,Seki A,Takeda H,Ishikawa T,Kuwano K

更新日期：2020-11-07 00:00:00

abstract：BACKGROUND:Scleromyxedema is a progressive, systemic connective tissue disorder characterized by fibro-mucous skin lesions and increased serum monoclonal immunoglobulin levels. Pulmonary involvement occurs in a subset of patients, though the overall prevalence of pulmonary lesions in scleromyxedema is unknown. Since pu...

journal_title：BMC pulmonary medicine

authors： Kreidy M,Al-Hilli A,Yachoui R,Resnick J

更新日期：2020-01-09 00:00:00

abstract：BACKGROUND:Asthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized control trial (RCT) is to evaluate short-term (end of rehabilitation) and intermediate-term effectiveness ...

journal_title：BMC pulmonary medicine

authors： Schultz K,Seidl H,Jelusic D,Wagner R,Wittmann M,Faller H,Nowak D,Schuler M

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:Primary Ciliary Dyskinesia (PCD) is also known as immotile-cilia syndrome, an autosomal recessive disorder of ciliary function, leading to mucus retention in the respiratory system in childhood. Our knowledge in the pathophysiological aspect of this devastating disorder is increasing with the advancement of ...

journal_title：BMC pulmonary medicine

authors： Al Mutairi F,Alkhalaf R,Alkhorayyef A,Alroqi F,Yusra A,Umair M,Nouf F,Khan A,Meshael A,Hamad A,Monira A,Asiri A,Alhamoudi KM,Alfadhel M

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND:The use of extracorporeal membrane oxygenation (ECMO) in awake, spontaneously breathing and non-intubated patients (awake ECMO) may be a novel therapeutic strategy for severe acute respiratory distress syndrome (ARDS) patients. The purpose of this study is to assess the feasibility and safety of awake ECMO i...

journal_title：BMC pulmonary medicine

authors： Xia J,Gu S,Li M,Liu D,Huang X,Yi L,Wu L,Fan G,Zhan Q

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:The effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study was to investigate whether a novel, community-based exercise program (CBE) was feasible and effective for pat...

journal_title：BMC pulmonary medicine

authors： Amin S,Abrazado M,Quinn M,Storer TW,Tseng CH,Cooper CB

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:The flow-volume (FV) curve pattern in the pulmonary function test (PFT) for obstructive lung diseases is widely recognized. However, there are few reports on FV curve pattern in idiopathic pulmonary fibrosis (IPF). In this study, we investigated the relationship between FV curve pattern and clinical or radio...

journal_title：BMC pulmonary medicine

authors： Nakagawa H,Otoshi R,Isomoto K,Katano T,Baba T,Komatsu S,Hagiwara E,Nakano Y,Kuwahira I,Ogura T

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Clinically hypomyopathic dermatomyositis is a rare disease that is important to recognize, investigate and treat early as it is associated with poor prognosis. In a proportion of patients, myositis specific antibodies could be negative, but with high clinical suspicion, myositis associated antibodies should ...

journal_title：BMC pulmonary medicine

authors： Alqatari S,Riddell P,Harney S,Henry M,Murphy G

更新日期：2018-04-17 00:00:00