Impact of a countywide smoke-free workplace law on emergency department visits for respiratory diseases: a retrospective cohort study.

abstract：BACKGROUND:The use of extracorporeal membrane oxygenation (ECMO) in awake, spontaneously breathing and non-intubated patients (awake ECMO) may be a novel therapeutic strategy for severe acute respiratory distress syndrome (ARDS) patients. The purpose of this study is to assess the feasibility and safety of awake ECMO i...

journal_title：BMC pulmonary medicine

authors： Xia J,Gu S,Li M,Liu D,Huang X,Yi L,Wu L,Fan G,Zhan Q

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:Innate T helper type 2 (Th2) immune responses mediated by interleukin (IL)-33, thymic stromal lymphopoietin (TSLP), and IL-25 have been shown to play an important role in pulmonary fibrosis of animal models; however, their clinical implications remain poorly understood. METHODS:TSLP, IL-25, and IL-33 concen...

journal_title：BMC pulmonary medicine

authors： Lee JU,Chang HS,Lee HJ,Jung CA,Bae DJ,Song HJ,Park JS,Uh ST,Kim YH,Seo KH,Park CS

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:IL-17A directly induces epithelial-mesenchymal transition (EMT) in alveolar epithelial cells. It could coordinate with cigarette smoke extract (CSE) to promote proliferation of bronchial epithelial cells. In this study, we aim to explore the direct effect of IL-17A and CSE on EMT in bronchial epithelial cell...

journal_title：BMC pulmonary medicine

authors： Ma L,Jiang M,Zhao X,Sun J,Pan Q,Chu S

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:As supra-physiological intake of corticosteroids is a well known risk factor for the development of adrenal insufficiency, we investigated the function of the hypothalamic-pituitary-adrenal (HPA) axis during a 14-day course of systemic corticosteroids in patients with acute exacerbation of chronic obstructiv...

journal_title：BMC pulmonary medicine

authors： Schuetz P,Christ-Crain M,Schild U,Süess E,Facompre M,Baty F,Nusbaumer C,Brutsche M,Müller B

更新日期：2008-01-26 00:00:00

abstract：BACKGROUND:Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality all over the world. Acute exacerbation of COPD (AECOPD) not only accelerates the progression of disease, but also causes hospital administration and death events. Epidemiologic studies have shown air pollution is a high ...

journal_title：BMC pulmonary medicine

authors： Zhou T,Zhong Y,Liao J,Wang G,Li X,Qian X,Xiang P,Chen X,Xu Z,Zhang F,Wang X,Wang S,Li X,Yu C,Zhang Y,Xia G,Dai L

更新日期：2019-01-25 00:00:00

abstract：BACKGROUND:Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that would change with treatment in terms of exercise capacity or lung function...

journal_title：BMC pulmonary medicine

authors： Wark PAB,Cookson K,Thiruchelvam T,Brannan J,Dorahy DJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:Although cigarette smoking may have a negative impact on the clinical outcome of pulmonary tuberculosis (PTB), few studies have investigated the impact of smoking-associated lung diseases. Emphysema is a major pathological finding of smoking-related lung damage. We aimed to clarify the effect of emphysema on...

journal_title：BMC pulmonary medicine

authors： Takasaka N,Seki Y,Fujisaki I,Uchiyama S,Matsubayashi S,Sato A,Yamanaka Y,Odashima K,Kazuyori T,Seki A,Takeda H,Ishikawa T,Kuwano K

更新日期：2020-11-07 00:00:00

abstract：:Following publication of the original article [1], the author flagged aspects of the article that affected readability of some of the article's scientific content. ...

journal_title：BMC pulmonary medicine

authors： Fuchs O,Bahmer T,Weckmann M,Dittrich AM,Schaub B,Rösler B,Happle C,Brinkmann F,Ricklefs I,König IR,Watz H,Rabe KF,Kopp MV,Hansen G,von Mutius E,ALLIANCE Study Group as part of the German Centre for Lung Research (DZL).

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:This study aims to investigate the effects of CCAAT/enhancer binding protein alpha (C/EBPα) overexpression on cell proliferation, apoptosis and surfactant protein-C(SP-C) in alveolar epithelial type II (AEC II) cells after exposure to hyperoxia. METHODS:pcDNA3.1(+)-C/EBPα plasmid or air-empty vector were tr...

journal_title：BMC pulmonary medicine

authors： Lu H,Chen X,Lu Y,Zhu H,Tang W,Wang Q

更新日期：2019-08-06 00:00:00

abstract：BACKGROUND:The acute respiratory distress syndrome (ARDS) is a serious disease in critically ill patients that is characterized by pulmonary dysfunctions, hypoxemia and significant mortality. Patients with immunodeficiency (e.g. SCID with T and B cell deficiency) are particularly susceptible to the development of sever...

journal_title：BMC pulmonary medicine

authors： Verjans E,Kanzler S,Ohl K,Rieg AD,Ruske N,Schippers A,Wagner N,Tenbrock K,Uhlig S,Martin C

更新日期：2018-11-22 00:00:00

abstract：BACKGROUND:Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) has an extremely poor prognosis and there is currently no effective treatment for this condition. Direct hemoperfusion with a polymyxin B-immobilized fiber column (PMX-DHP) improves oxygenation, but it is unclear whether treatment of AE-IPF with PM...

journal_title：BMC pulmonary medicine

authors： Enomoto N,Mikamo M,Oyama Y,Kono M,Hashimoto D,Fujisawa T,Inui N,Nakamura Y,Yasuda H,Kato A,Mimuro S,Doi M,Sato S,Suda T

更新日期：2015-02-22 00:00:00

abstract：BACKGROUND:Omega-3 fatty acids, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and derivatives, play a key role in the resolution of inflammation. Higher intake has been linked to decreased morbidity in several diseases, though effects on respiratory diseases like COPD are...

journal_title：BMC pulmonary medicine

authors： Lemoine S CM,Brigham EP,Woo H,Hanson CK,McCormack MC,Koch A,Putcha N,Hansel NN

更新日期：2019-05-21 00:00:00

abstract：BACKGROUND:In bronchiectasis patients, chronic Pseudomonas aeruginosa (PA) infection has been associated with worse health-related quality of life (HRQL), but little is known about Mycobacterium avium complex lung disease (MACLD) patients in this context. This study aimed to evaluate HRQL and investigate the impact of ...

journal_title：BMC pulmonary medicine

authors： Kamata H,Asakura T,Suzuki S,Namkoong H,Yagi K,Funatsu Y,Okamori S,Uno S,Uwamino Y,Fujiwara H,Nishimura T,Ishii M,Betsuyaku T,Hasegawa N

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:The pathological appearance of idiopathic pleuroparenchymal fibroelastosis (IPPFE) with hematoxylin-eosin staining is similar to that of usual interstitial pneumonia (UIP) in patients with idiopathic pulmonary fibrosis (IPF). The amount of elastic fibers (EF) and detailed differences between IPPFE and IPF ha...

journal_title：BMC pulmonary medicine

authors： Enomoto N,Kusagaya H,Oyama Y,Kono M,Kaida Y,Kuroishi S,Hashimoto D,Fujisawa T,Yokomura K,Inui N,Nakamura Y,Suda T

更新日期：2014-05-28 00:00:00

abstract：BACKGROUND:Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore, it is necessary to evaluate perioperative management using new inhalant drugs in patients with obs...

journal_title：BMC pulmonary medicine

authors： Numata T,Nakayama K,Fujii S,Yumino Y,Saito N,Yoshida M,Kurita Y,Kobayashi K,Ito S,Utsumi H,Yanagisawa H,Hashimoto M,Wakui H,Minagawa S,Ishikawa T,Hara H,Araya J,Kaneko Y,Kuwano K

更新日期：2018-01-09 00:00:00

abstract：BACKGROUND:One forth whole-world population is infected with Mycobacterium tuberculosis (Mtb), but 90% of them are asymptotic latent infection without any symptoms but positive result in IFN-γ release assay. There is lack of ideal strategy to distinguish active tuberculosis (TB) and latent tuberculosis infection (LTBI)...

journal_title：BMC pulmonary medicine

authors： Wei Z,Li Y,Wei C,Li Y,Xu H,Wu Y,Jia Y,Guo R,Jia J,Qi X,Li Z,Gao X

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND:Exacerbations, a leading cause of hospitalization in patients with chronic obstructive pulmonary disease (COPD), affect the quality of life and prognosis. Treatment recommendations as provided in the evidence-based guidelines are not consistently followed, partly due to absence of simplified task-oriented ap...

journal_title：BMC pulmonary medicine

authors： Ban A,Ismail A,Harun R,Abdul Rahman A,Sulung S,Syed Mohamed A

更新日期：2012-06-22 00:00:00

abstract：BACKGROUND:The Darlington and Northallerton Asthma Study is an observational cohort study started in 1983. At that time little was published about long term outcome in asthma and the contribution of change in reversible disease or airway remodelling to any excess deterioration in function. The study design included reg...

journal_title：BMC pulmonary medicine

authors： Connolly CK,Prescott RJ

更新日期：2005-01-31 00:00:00

abstract：BACKGROUND:COVID-19 is a systemic viral infection which mainly targets the human respiratory system with many secondary clinical manifestations especially affecting the hematopoietic system and haemostasis. Few studies have highlighted the prognostic value of blood findings such as lymphopenia, neutrophil/lymphocyte ra...

journal_title：BMC pulmonary medicine

authors： Lim AYH,Goh JL,Chua MCW,Heng BH,Abisheganaden JA,George PP

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:During the last few years, investigators have debated the role that infectious agents may have in sarcoidosis pathogenesis. With the emergence of new molecular biology techniques, several studies have been conducted; therefore, we performed a meta-analysis in order to better explain this possible association...

journal_title：BMC pulmonary medicine

authors： Esteves T,Aparicio G,Garcia-Patos V

更新日期：2016-11-28 00:00:00

abstract：BACKGROUND:The purpose of our study was to assess the frequency of occult foreign body aspiration (FBA) and to evaluate the diagnostic difficulties and therapeutic methods for these patients. METHODS:Between May 2000 and May 2020, 3557 patients with the diagnosis of FBA were treated in our department. Thirty-five pati...

journal_title：BMC pulmonary medicine

authors： Liu B,Ding F,An Y,Li Y,Pan Z,Wang G,Dai J,Li H,Wu C

更新日期：2020-12-09 00:00:00

abstract：BACKGROUND:Eotaxin proteins are a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases. Since inflammation is often associated with an increased generation of reactive oxygen species (ROS), oxidative stress is a mechanistically imperative factor in asthma. Ast...

journal_title：BMC pulmonary medicine

authors： Cho IH,Gong JH,Kang MK,Lee EJ,Park JH,Park SJ,Kang YH

更新日期：2014-07-29 00:00:00

abstract：BACKGROUND:The breakdown of alveolar barrier dysfunction contributes to Lipopolysaccharide stimulated pulmonary edema and acute lung injury. Actin cytoskeleton has been implicated to be critical in regulation of epithelial barrier. Here, we performed in vivo and in vitro study to investigate role of TLR4-p38 MAPK-Hsp27...

journal_title：BMC pulmonary medicine

authors： Wang W,Weng J,Yu L,Huang Q,Jiang Y,Guo X

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Asthma is a heterogeneous disease and understanding this heterogeneity will enable the realisation of precision medicine. We sought to compare the sputum and serum inflammatory profiles in moderate-to-severe asthma during stable disease and exacerbation events. METHODS:We recruited 102 adults and 34 childre...

journal_title：BMC pulmonary medicine

authors： Ghebre MA,Pang PH,Desai D,Hargadon B,Newby C,Woods J,Rapley L,Cohen SE,Herath A,Gaillard EA,May RD,Brightling CE

更新日期：2019-08-08 00:00:00

abstract：BACKGROUND:In adults, overweight is associated with reduced lung function, in children evidence on this association is conflicting. We examined the association of body mass index (BMI) and waist circumference (WC) at age 12, and of persistently (at ages 8 and 12 years) high BMI and large WC, with forced vital capacity ...

journal_title：BMC pulmonary medicine

authors： Bekkers MB,Wijga AH,Gehring U,Koppelman GH,de Jongste JC,Smit HA,Brunekreef B

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:Dose intensity and dose density of first line Platinum and Etoposide (PE) do not influence Overall Survival (OS) of Small Cell Lung Cancer (SCLC) patients. The effect of treatment length, however, remains unclear. Current guidelines recommend treating beyond 4 cycles -up to 6-, in patients that respond to an...

journal_title：BMC pulmonary medicine

authors： Sallam M,Wong H,Escriu C

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a form of chronic fibrosing interstitial pneumonia characterized by progressive worsening of dyspnea and lung function, with a poor prognosis. The objective of this study was to determine treatment patterns, resource use and costs of managing Spanish patients with IPF. ...

journal_title：BMC pulmonary medicine

authors： Morell F,Esser D,Lim J,Stowasser S,Villacampa A,Nieves D,Brosa M

更新日期：2016-01-12 00:00:00

abstract：BACKGROUND:Asthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized control trial (RCT) is to evaluate short-term (end of rehabilitation) and intermediate-term effectiveness ...

journal_title：BMC pulmonary medicine

authors： Schultz K,Seidl H,Jelusic D,Wagner R,Wittmann M,Faller H,Nowak D,Schuler M

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) with carbon dioxide retention is associated with a worsening clinical condition and the beginning of pulmonary ventilation decompensation. This study aimed to identify the factors associated with carbon dioxide retention. METHODS:This was a retrospective study of...

journal_title：BMC pulmonary medicine

authors： Wei X,Yu N,Ding Q,Ren J,Mi J,Bai L,Li J,Qi M,Guo Y

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Appropriate sedation benefits patients by reducing the stress response, but it requires an appropriate method of assessment to adjust the dosage of sedatives. The aim of this study was to compare the difference in the sedation of mechanically ventilated patients undergoing flexible bronchoscopy (FB) monitore...

journal_title：BMC pulmonary medicine

authors： Hsu CW,Sun SF,Chu KA,Lee DL,Wong KF

更新日期：2014-02-06 00:00:00