Efficacy of glucocorticoids for the treatment of macrolide refractory mycoplasma pneumonia in children: meta-analysis of randomized controlled trials.

abstract：BACKGROUND:The incidence and prevalence of chronic kidney disease (CKD) continue to rise worldwide. Increasing age, diabetes, hypertension, and cigarette smoking are well-recognized risk factors for CKD. Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation leading to airway obstr...

journal_title：BMC pulmonary medicine

authors： Gaddam S,Gunukula SK,Lohr JW,Arora P

更新日期：2016-11-24 00:00:00

abstract：BACKGROUND:Despite advances in asthma treatment, severe asthma (SA) still results in high morbidity and use of health resources. Our hypothesis was that SA patients would achieve adequate control with a systematic protocol, including oral corticosteroids, budesonide/formoterol maintenance and reliever therapy and a mul...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Carvalho-Pinto R,Fernandes FL,Rached S,Rabe K,Cukier A,Stelmach R

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities. The main causes of COPD are Gene-environment interactions associated with tobacco smoking (COPD-TS) and biomass smoke (COPD-BS). It is w...

journal_title：BMC pulmonary medicine

authors： Velasco-Torres Y,Ruiz-López V,Pérez-Bautista O,Buendía-Roldan I,Ramírez-Venegas A,Pérez-Ramos J,Falfán-Valencia R,Ramos C,Montaño M

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Sarcoidosis is a systemic granulomatous disease caused by CD4+ cell-dominant inflammation. Meanwhile, diffuse panbronchiolitis is a chronic inflammatory respiratory disease predominantly caused by CD8+ lymphocytes and neutrophils. Herein, we report a rare case of sarcoidosis in which the clinical presentatio...

journal_title：BMC pulmonary medicine

authors： Akaba T,Takeyama K,Kondo M,Kobayashi F,Okabayashi A,Sawada T,Tagaya E

更新日期：2020-03-30 00:00:00

abstract：BACKGROUND:This study aims to investigate the effects of CCAAT/enhancer binding protein alpha (C/EBPα) overexpression on cell proliferation, apoptosis and surfactant protein-C(SP-C) in alveolar epithelial type II (AEC II) cells after exposure to hyperoxia. METHODS:pcDNA3.1(+)-C/EBPα plasmid or air-empty vector were tr...

journal_title：BMC pulmonary medicine

authors： Lu H,Chen X,Lu Y,Zhu H,Tang W,Wang Q

更新日期：2019-08-06 00:00:00

abstract：BACKGROUND:The FACED score is an easy-to-use multidimensional grading system that has demonstrated an excellent prognostic value for mortality in patients with bronchiectasis. A Spanish group developed the score but no multicenter international validation has yet been published. METHODS:Retrospective and multicenter s...

journal_title：BMC pulmonary medicine

authors： Athanazio R,Pereira MC,Gramblicka G,Cavalcanti-Lundgren F,de Figueiredo MF,Arancibia F,Rached S,de la Rosa D,Máiz-Carro L,Girón R,Olveira C,Prados C,Martinez-Garcia MA

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:In bronchiectasis patients, chronic Pseudomonas aeruginosa (PA) infection has been associated with worse health-related quality of life (HRQL), but little is known about Mycobacterium avium complex lung disease (MACLD) patients in this context. This study aimed to evaluate HRQL and investigate the impact of ...

journal_title：BMC pulmonary medicine

authors： Kamata H,Asakura T,Suzuki S,Namkoong H,Yagi K,Funatsu Y,Okamori S,Uno S,Uwamino Y,Fujiwara H,Nishimura T,Ishii M,Betsuyaku T,Hasegawa N

更新日期：2017-12-13 00:00:00

abstract：BACKGROUND:Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwide setting in patients with uncontrolled asthma. We defined uncontrolled asthma as a previous hospit...

journal_title：BMC pulmonary medicine

authors： Gullach AJ,Risgaard B,Lynge TH,Jabbari R,Glinge C,Haunsø S,Backer V,Winkel BG,Tfelt-Hansen J

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:The acute respiratory distress syndrome (ARDS) is a serious disease in critically ill patients that is characterized by pulmonary dysfunctions, hypoxemia and significant mortality. Patients with immunodeficiency (e.g. SCID with T and B cell deficiency) are particularly susceptible to the development of sever...

journal_title：BMC pulmonary medicine

authors： Verjans E,Kanzler S,Ohl K,Rieg AD,Ruske N,Schippers A,Wagner N,Tenbrock K,Uhlig S,Martin C

更新日期：2018-11-22 00:00:00

abstract：BACKGROUND:The breakdown of alveolar barrier dysfunction contributes to Lipopolysaccharide stimulated pulmonary edema and acute lung injury. Actin cytoskeleton has been implicated to be critical in regulation of epithelial barrier. Here, we performed in vivo and in vitro study to investigate role of TLR4-p38 MAPK-Hsp27...

journal_title：BMC pulmonary medicine

authors： Wang W,Weng J,Yu L,Huang Q,Jiang Y,Guo X

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Clinical guidelines specify that diagnosis of interstitial pulmonary fibrosis (IPF) requires identification of usual interstitial pneumonia (UIP) pattern. While UIP can be identified by high resolution CT of the chest, the results are often inconclusive, making surgical lung biopsy necessary to reach a defin...

journal_title：BMC pulmonary medicine

authors： Choi Y,Lu J,Hu Z,Pankratz DG,Jiang H,Cao M,Marchisano C,Huiras J,Fedorowicz G,Wong MG,Anderson JR,Tom EY,Babiarz J,Imtiaz U,Barth NM,Walsh PS,Kennedy GC,Huang J

更新日期：2017-11-17 00:00:00

abstract：BACKGROUND:Innate T helper type 2 (Th2) immune responses mediated by interleukin (IL)-33, thymic stromal lymphopoietin (TSLP), and IL-25 have been shown to play an important role in pulmonary fibrosis of animal models; however, their clinical implications remain poorly understood. METHODS:TSLP, IL-25, and IL-33 concen...

journal_title：BMC pulmonary medicine

authors： Lee JU,Chang HS,Lee HJ,Jung CA,Bae DJ,Song HJ,Park JS,Uh ST,Kim YH,Seo KH,Park CS

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:Anti-tuberculosis therapy requires at least six-month treatment with continuous administration of combined antibiotics, including isoniazid, rifampicin, pyrazinamide, and ethambutol. The long-term exposure to antibiotics could cause consequent changes in gut microbiota, which may alter the gastrointestinal f...

journal_title：BMC pulmonary medicine

authors： Shi W,Hu Y,Zheng X,Ning Z,Wu M,Xia F,Prast-Nielsen S,Hu YOO,Xu B

更新日期：2019-11-11 00:00:00

abstract：:Following publication of the original article [1], the author flagged aspects of the article that affected readability of some of the article's scientific content. ...

journal_title：BMC pulmonary medicine

authors： Fuchs O,Bahmer T,Weckmann M,Dittrich AM,Schaub B,Rösler B,Happle C,Brinkmann F,Ricklefs I,König IR,Watz H,Rabe KF,Kopp MV,Hansen G,von Mutius E,ALLIANCE Study Group as part of the German Centre for Lung Research (DZL).

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:IL-4 and IL-13 play a critical yet poorly understood role in orchestrating the recruitment and activation of effector cells of the asthmatic response and driving the pathophysiology of allergic asthma. The house dust mite (HDM) sheep asthma model displays many features of the human condition and is an ideal ...

journal_title：BMC pulmonary medicine

authors： Liravi B,Piedrafita D,Nguyen G,Bischof RJ

更新日期：2015-09-11 00:00:00

abstract：BACKGROUND:The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) and the Medical Outcomes Study Short Form 36 (SF-36) are widely used to assess patient-reported outcome in individuals with pulmonary hypertension (PH). The aim of the study was to compare the psychometric properties of the two measures. METHODS:...

journal_title：BMC pulmonary medicine

authors： Twiss J,McKenna S,Ganderton L,Jenkins S,Ben-L'amri M,Gain K,Fowler R,Gabbay E

更新日期：2013-07-12 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a disease with poor prognosis mainly affecting males. Differences in clinical presentation between genders may be important both for the diagnostic work-up and for follow-up. In the present study, we therefore explored potential gender differences at presentation in a S...

journal_title：BMC pulmonary medicine

authors： Kalafatis D,Gao J,Pesonen I,Carlson L,Sköld CM,Ferrara G

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Asthma patients are enrolled in multimodal pulmonary rehabilitation (PR) programs. However, available data for the effectiveness of PR in asthma are sparse. Therefore, the primary aim of this randomized control trial (RCT) is to evaluate short-term (end of rehabilitation) and intermediate-term effectiveness ...

journal_title：BMC pulmonary medicine

authors： Schultz K,Seidl H,Jelusic D,Wagner R,Wittmann M,Faller H,Nowak D,Schuler M

更新日期：2017-03-09 00:00:00

abstract：BACKGROUND:The tissue factor (TF)-dependent extrinsic pathway has been suggested to be a central mechanism by which the coagulation cascade is locally activated in the lungs of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) and thus represents an attractive target for therapeutic int...

journal_title：BMC pulmonary medicine

authors： Morris PE,Steingrub JS,Huang BY,Tang S,Liu PM,Rhode PR,Wong HC

更新日期：2012-02-16 00:00:00

abstract：BACKGROUND:Chlamydia psittaci pneumonia is a zoonotic infectious disease caused by Chlamydia psittaci. Diagnostic tools, including culture, serologic test and PCR-based methods, are available but prone to false negative results. CASE PRESENTATION:This report included five cases of Chlamydia psittaci pneumonia. Symptom...

journal_title：BMC pulmonary medicine

authors： Gu L,Liu W,Ru M,Lin J,Yu G,Ye J,Zhu ZA,Liu Y,Chen J,Lai G,Wen W

更新日期：2020-03-17 00:00:00

abstract：BACKGROUND:With the goal of reducing exposure to secondhand smoke, the state of Minnesota (MN), enacted a smoke-free law (i.e., Freedom to Breathe Act) in all workplaces, restaurants, and bars in 2007. This retrospective cohort study analyzes emergency department (ED) visits in Olmsted County, MN, for chronic obstructi...

journal_title：BMC pulmonary medicine

authors： Croghan IT,Ebbert JO,Hays JT,Schroeder DR,Chamberlain AM,Roger VL,Hurt RD

更新日期：2015-01-22 00:00:00

abstract：BACKGROUND:This study was conducted in order to determine the prevalence of asthma and associated risk factors in the adult population of Karachi, Pakistan. METHODS:This multi-stage, cross-sectional survey was conducted from May 2014-August 2015; comprising 1629 adults in 75 randomly selected clusters in Karachi, Paki...

journal_title：BMC pulmonary medicine

authors： Razzaq S,Nafees AA,Rabbani U,Irfan M,Naeem S,Khan MA,Fatmi Z,Burney P

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:Recurrent airway infections are common in patients with Down's syndrome (DS). Hence, ruling out Cystic Fibrosis (CF) in these patients is often required. In the past, the value of sweat testing - the gold standard to diagnose CF - has been questioned in DS as false positive results have been reported. Howeve...

journal_title：BMC pulmonary medicine

authors： Ruf K,Demerath A,Hebestreit H,Kunzmann S

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe hypersensitivity drug reaction involving the skin and multiple internal organ systems. The symptoms typically present with fever and skin rash, and rapidly progress to multiple organ failures. Vancomycin is a rare drug to cause DRESS s...

journal_title：BMC pulmonary medicine

authors： Wilcox O,Hassanein M,Armstrong J,Kassis N

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:Mechanical ventilation (MV), compared to spontaneous breathing (SB), has been found to increase abdominal edema and inflammation in experimental sepsis. Our hypothesis was that in primary acute respiratory distress syndrome (ARDS) MV would enhance inflammation and edema in the abdomen. METHODS:Thirteen pigl...

journal_title：BMC pulmonary medicine

authors： Marchesi S,Hedenstierna G,Hata A,Feinstein R,Larsson A,Larsson AO,Lipcsey M

更新日期：2020-04-25 00:00:00

abstract：BACKGROUND:CHCHD2 was identified a novel cell migration-promoting gene, which could promote cell migration and altered cell adhesion when ectopically overexpressed in NIH3T3 fibroblasts, and it was identified as a protein necessary for OxPhos function as well. However, the clinic relevance of CHCHD2 expression in NSCLC...

journal_title：BMC pulmonary medicine

authors： Yin X,Xia J,Sun Y,Zhang Z

更新日期：2020-02-13 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a distinct form of interstitial pneumonia with unknown origin and poor prognosis. Current pharmacologic treatments are limited and lung transplantation is a viable option for appropriate patients. The aim of this review was to summarize lung transplantation survival in ...

journal_title：BMC pulmonary medicine

authors： Kistler KD,Nalysnyk L,Rotella P,Esser D

更新日期：2014-08-16 00:00:00

abstract：BACKGROUND:Clinically hypomyopathic dermatomyositis is a rare disease that is important to recognize, investigate and treat early as it is associated with poor prognosis. In a proportion of patients, myositis specific antibodies could be negative, but with high clinical suspicion, myositis associated antibodies should ...

journal_title：BMC pulmonary medicine

authors： Alqatari S,Riddell P,Harney S,Henry M,Murphy G

更新日期：2018-04-17 00:00:00

abstract：BACKGROUND:Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that would change with treatment in terms of exercise capacity or lung function...

journal_title：BMC pulmonary medicine

authors： Wark PAB,Cookson K,Thiruchelvam T,Brannan J,Dorahy DJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:IL-17A directly induces epithelial-mesenchymal transition (EMT) in alveolar epithelial cells. It could coordinate with cigarette smoke extract (CSE) to promote proliferation of bronchial epithelial cells. In this study, we aim to explore the direct effect of IL-17A and CSE on EMT in bronchial epithelial cell...

journal_title：BMC pulmonary medicine

authors： Ma L,Jiang M,Zhao X,Sun J,Pan Q,Chu S

更新日期：2020-01-30 00:00:00