Correction to: In memory of Professor Domenico Andreani.

abstract：BACKGROUND:Persistence is commonly considered a key factor for the successful management of osteoporosis and fragility fractures. Denosumab is the first biologic agent developed for the treatment of osteoporosis with satisfying data regarding the persistence with this therapy. AIM:The purpose of this multicenter obser...

journal_title：Journal of endocrinological investigation

authors： Migliaccio S,Francomano D,Romagnoli E,Marocco C,Fornari R,Resmini G,Buffa A,Di Pietro G,Corvaglia S,Gimigliano F,Moretti A,de Sire A,Malavolta N,Lenzi A,Greco EA,Iolascon G

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:Testosterone replacement therapy (TRT) is recommended for the treatment of most cases of male hypogonadism. Transdermal testosterone (T) gels are commonly used in clinical practice; however, there is little evidence concerning how to monitor dosage to bring and maintain serum T levels in the normal physiologic ...

journal_title：Journal of endocrinological investigation

authors： Sansone A,Sansone M,Selleri R,Schiavo A,Gianfrilli D,Pozza C,Zitzmann M,Lenzi A,Romanelli F

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The adiponectin gene has been identified as a susceptibility locus for metabolic syndrome, diabetes and cardiovascular disease. AIM:To examine the influence of two single nucleotide polymorphisms (SNPs) of this gene (+276G>T and +45T>G) on circulating adiponectin concentrations, and to evaluate their relati...

journal_title：Journal of endocrinological investigation

authors： Galcheva SV,Martorana D,Iotova VM,Yotov Y,Neri TM,Street ME

更新日期：2013-11-01 00:00:00

abstract：:Testosterone therapy has been reported to be useful in the treatment of hypogonadism and partial androgen deficiency of the aging male (PADAM) syndrome. Testosterone administration is needed in order to maintain secondary sexual characteristics, muscle mass, bone mineral density, cognitive function and sexual drive. N...

journal_title：Journal of endocrinological investigation

authors： Volpi R,Coiro V,Chiodera P,Saccani-Jotti G,Delsignore R

更新日期：2005-01-01 00:00:00

abstract：:A 45-year-old man presented with gynecomastia, hypertension and a large left adrenal mass. Further evaluation revealed elevated serum concentrations of estrogen, estrone sulfate, androstenedione, dehydroepiandrosterone, dehydroepiandrosterone sulfate, deoxycorticosterone, and aldosterone and increased 24-hour urinary ...

journal_title：Journal of endocrinological investigation

authors： Zayed A,Stock JL,Liepman MK,Wollin M,Longcope C

更新日期：1994-04-01 00:00:00

abstract：:Final height was evaluated in 47 patients with classical 21-hydroxylase treated since diagnosis, and in 29 patients with nonclassical (NC) 21-hydroxylase deficiency who had never been treated before reaching final adult height. Classical patients achieved final heights consistently below the mean for the general popul...

journal_title：Journal of endocrinological investigation

authors： New MI,Gertner JM,Speiser PW,Del Balzo P

更新日期：1989-01-01 00:00:00

abstract：:Human GH (hGH) is a heterogeneous protein hormone consisting of several isoforms. This heterogeneity is the consequence of multiple hGH genes, mRNA splicing, post-translational modifications, and peripheral metabolism, and it represents one important reason for the disparity among GH assay results from different labor...

journal_title：Journal of endocrinological investigation

authors： Rigamonti AE,Bozzola M,Banfi G,Meazza C,Müller EE,Cella SG

更新日期：2012-11-01 00:00:00

abstract：:Pendred syndrome is an autosomal recessive disorder characterized by congenital sensorineural deafness, goiter, and impaired iodide organification. It is caused by mutations in the PDS gene. Most published mutation studies of Pendred syndrome have dealt with Western populations. In this study, we examined clinical and...

journal_title：Journal of endocrinological investigation

authors： Snabboon T,Plengpanich W,Saengpanich S,Sirisalipoch S,Keelawat S,Sunthornyothin S,Khovidhunkit W,Suwanwalaikorn S,Sridama V,Shotelersuk V

更新日期：2007-12-01 00:00:00

abstract：:Lipopolysaccharide (LPS)-induced inflammatory stress activates the hypothalamus-pituitary-adrenal (HPA) function. Interleukin-I (IL-1) is one of the key factors during this event; however, the mechanisms mediating IL-1 stimulation of HPA axis are still unclear. The present study evaluated the possible involvement of g...

journal_title：Journal of endocrinological investigation

authors： Guo AL,Petraglia F,Nappi RE,Criscuolo M,Ficarra G,Salvestroni C,Genazzani AD,Trentini GP,Genazzani AR

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Elevated γ-glutamyl transpeptidase (GGT) and alanine aminotransferase (ALT) could predict the risk of Type 2 diabetes (T2D), but the reason for their elevation was unclear. GGT and ALT mediated the metabolism of many amino acids (AA). Up to now, it was not investigated whether abnormal AA concentration was a...

journal_title：Journal of endocrinological investigation

authors： Chen T,Zhang X,Long Y,Yu H,Ran X,Gao Y,Lu H,Xie X,Chen X,Ren Y,Shi J,Tian H

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:To review the proportion of diabetic patients reaching recommended therapeutic goals, as reported in intervention trials and observational studies, and to analyse the factors associated with success or failure in achieving these targets. METHODS:A systematic review and meta-analysis through a Medline and Embas...

journal_title：Journal of endocrinological investigation

authors： Mannucci E,Monami M,Dicembrini I,Piselli A,Porta M

更新日期：2014-05-01 00:00:00

abstract：:The underlying mechanism leading to carcinogenesis involves genomic instability, likely related to aneuploidy. While p53 as a "guardian of the genome" is an appealing candidate as an initiator of genomic instability, its mutations or deletions usually occur late in the course of tumor progression. P53 may, however, be...

journal_title：Journal of endocrinological investigation

authors： Farid NR

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Neuroendocrine dysfunction in polycystic ovary syndrome (PCOS) was addressed by studying the steroid hormone changes in women with PCOS with either high or normal LH levels leading to inferences regarding the primacy of elevated LH in the pathophysiology of PCOS. METHODS:A cross-sectional study was designed ...

journal_title：Journal of endocrinological investigation

authors： Doi SA,Al-Zaid M,Towers PA,Scott CJ,Al-Shoumer KA

更新日期：2005-11-01 00:00:00

abstract：:Nutritional and hormonal milieu in utero affect fetal growth. Both parties involved have an independent chance, for the occurrence of a developmental error at any stage of their constant developing system. Studies suggest that pregnancy outcome is associated with fetal demand for nutrients and the materno-placental ca...

journal_title：Journal of endocrinological investigation

authors： Zadik Z

更新日期：2003-09-01 00:00:00

abstract：:Numerous clinical and experimental reports suggest that a high von Willebrand factor (vWf) level reflects endothelial damage or endothelial dysfunction. The present study was designed to evaluate vWf in subclinical hyperthyroidic subjects compared with euthyroidic subjects. We selected 20 subclinical hyperthyroidic su...

journal_title：Journal of endocrinological investigation

authors： Coban E,Aydemir M,Yazicioglu G,Ozdogan M

更新日期：2006-03-01 00:00:00

abstract：:Seventy-one white women within 6 months to 6 years postmenopause were randomly assigned to three treatment groups: (a) placebo, (b) calcium, (c) cyclic estrogen-progestin plus calcium. Calcium was given as calcium carbonate with meals to attain an intake of 1,700 mg daily in the latter two groups. All women received 4...

journal_title：Journal of endocrinological investigation

authors： Aloia JF,Vaswani A,Yeh JK,McGowan DM,Ross P

更新日期：1991-12-01 00:00:00

abstract：:Abnormal nutritional status is an increasingly common complication in developed countries and, as reproductive age women are a part of this trend, the effect of maternal obesity on the pregnancy and neonate must be investigated. Pregestational obesity or overweight condition or an excessive gestational weight gain can...

journal_title：Journal of endocrinological investigation

authors： Triunfo S,Lanzone A

更新日期：2014-04-01 00:00:00

abstract：:The distribution of goiter prevalence in schoolchildren (no.=13,984, age 6-14 yr), the neonatal TSH results obtained from the congenital hypothyroidism screening program and the urinary iodine excretion values (no.=284) were employed for the assessment of iodine deficiency in Calabria, a Southern Italy region. Data we...

journal_title：Journal of endocrinological investigation

authors： Costante G,Grasso L,Schifino E,Marasco MF,Crocetti U,Capula C,Chiarella R,Ludovico O,Nocera M,Parlato G,Filetti S

更新日期：2002-03-01 00:00:00

abstract：CONTEXT:The latest guidelines of the 4th International Workshop on Asymptomatic Primary Hyperparathyroidism (aPHPT) reintroduced hypercalciuria (i.e. urinary calcium > 400 mg/day) as criterion for surgery. However, the value of hypercalciuria as a predictor of nephrolithiasis and the correct cut-off values still need t...

journal_title：Journal of endocrinological investigation

authors： Saponaro F,Cetani F,Mazoni L,Apicella M,Di Giulio M,Carlucci F,Scalese M,Pardi E,Borsari S,Bilezikian JP,Marcocci C

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:The aims of the present study were to examine gene and protein expression of the vitamin D-inactivating 24-hyroxylase (CYP24A1) and the activating 1-alpha-hydroxylase (CYP27B1) enzyme in human papillary thyroid cancer (PTC), furthermore, to investigate the association between CYP24A1 expression and numerous c...

journal_title：Journal of endocrinological investigation

authors： Balla B,Tobiás B,Kósa JP,Podani J,Horváth P,Nagy Z,Horányi J,Járay B,Székely E,Krenács L,Árvai K,Dank M,Putz Z,Szabó B,Szili B,Valkusz Z,Vasas B,Győri G,Lakatos P,Takács I

更新日期：2015-03-01 00:00:00

abstract：:Forty-three euthyroid patients with a single, solid, nonfunctioning thyroid nodule were submitted to fine needle aspiration biopsy and serum thyroglobulin (Tg) was measured before and after (48h) 10 U of bovine TSH. Twenty-two normal subjects were also submitted to the bTSH test. Patients with nonfunctioning nodules w...

journal_title：Journal of endocrinological investigation

authors： Leite Z,Carneiro P,Halpern A,Medeiros-Neto G

更新日期：1987-06-01 00:00:00

abstract：:Vitamin D via its receptor has essential actions on parathyroid cells, inhibiting PTH secretion, and parathyroid cell proliferation. While the effects of vitamin D depletion in the pathogenesis of secondary hyperparathyroidism in elderly individuals or in the occurrence of parathyroid hyperplasia in patients with rena...

journal_title：Journal of endocrinological investigation

authors： Nuti R,Merlotti D,Gennari L

更新日期：2011-07-01 00:00:00

abstract：:Over the past years, the use of genetically encoded Ca(2+) indicators (GECIs), derived from aequorin and green fluorescent protein, has profoundly transformed the study of Ca(2+) homeostasis in living cells leading to novel insights into functional aspects of Ca(2+) signalling. Particularly relevant for a deeper under...

journal_title：Journal of endocrinological investigation

authors： Pendin D,Greotti E,Filadi R,Pozzan T

更新日期：2015-01-01 00:00:00

abstract：:In addition to growth hormone (GH), sex hormones are important determinants of body composition. Aging is accompanied by a decrease in free testosterone levels and, as BMI as well as fat mass increase with age (with a redistribution of body fat), whereas muscle mass decreases, it is tempting to attribute a causal role...

journal_title：Journal of endocrinological investigation

authors： Vermeulen A,Goemaere S,Kaufman JM

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:Wolfram syndrome (WS) is a rare disorder caused by mutations in WFS1 that is characterized by diabetes mellitus, optic atrophy, sensorineural deafness, diabetes insipidus, and neurodegeneration. This disease is usually inherited as an autosomal recessive trait, but an autosomal dominant form has been reported. ...

journal_title：Journal of endocrinological investigation

authors： Batjargal K,Tajima T,Jimbo EF,Yamagata T

更新日期：2020-09-01 00:00:00

abstract：:Basal IGF-I levels and the GH response to at least two among provocative stimuli such as clonidine (CLO, Catapresan, 150 mcg/m2 p.o.), GHRH (1 mcg/kg i.v.)+arginine (ARG, 0.5 g/kg i.v. infusion during 30 min) and GHRH+pyridostigmine (PD, Mestinon cpr 60 mg p.o.) have been evaluated in 43 children with Prader-Willi syn...

journal_title：Journal of endocrinological investigation

authors： Corrias A,Bellone J,Beccaria L,Bosio L,Trifirò G,Livieri C,Ragusa L,Salvatoni A,Andreo M,Ciampalini P,Tonini G,Crinò A

更新日期：2000-02-01 00:00:00

abstract：:The autosomal dominant familial neurohypophyseal diabetes insipidus (adFNDI) is caused by diverse mutations in one allele of the gene that encodes the arginine vasopressin (AVP) precursor protein, AVP-neurophysin II (AVP-NP II). Most of the mutations identified so far are located in either the signal peptide or NP II ...

journal_title：Journal of endocrinological investigation

authors： Kobayashi H,Fujisawa I,Ikeda K,Son C,Iwakura T,Yoshimoto A,Kasahara M,Ishihara T,Ogawa Y

更新日期：2006-03-01 00:00:00

abstract：:Liver function is well maintained with increasing age. The aim of our study was to investigate if long-term moderate (

journal_title：Journal of endocrinological investigation

authors： Pinzani P,Petruzzi E,Orlando C,Malentacchi F,Petruzzi I,Pazzagli M,Masotti G

更新日期：2005-01-01 00:00:00

abstract：:Seasonal plasma testosterone and androstenedione levels were determined by radioimmunoassay in the Gentile di Puglia ram. Androstenedione remains steady throughout the years, while testosterone shows seasonal changes. Testosterone is at high levels in winter, spring and summer and drops to a low concentration in autum...

journal_title：Journal of endocrinological investigation

authors： Dell'Aquila S,Crasto A,Alberico G,Varriale B,Pelosi A,Pierantoni R

更新日期：1985-06-01 00:00:00

abstract：PURPOSE:We examined auxological changes in growth hormone (GH)-treated children in Italy using data from the Italian cohort of the multinational observational Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS) of pediatric patients requiring GH treatment. METHODS:We studied 711 children (me...

journal_title：Journal of endocrinological investigation

authors： Cappa M,Iughetti L,Loche S,Maghnie M,Vottero A,GeNeSIS National Board on behalf of the GeNeSIS Italian Investigators.

更新日期：2016-06-01 00:00:00