Chinese herbal medicine bi min fang for allergic rhinitis: protocol for a double-blind, double-dummy, randomized controlled trial.

abstract：BACKGROUND:Visible light (400 to 700 nm) is common in our environment, comprising 44% of total solar radiation and a large component of environmental light exposure. The effects of visible light on skin remain undefined. The red light portion of the visible spectrum (600 to 700 nm) may be used to treat skin diseases as...

journal_title：Trials

authors： Wang EB,Kaur R,Nguyen J,Ho D,Austin E,Maverakis E,Li CS,Hwang ST,Isseroff RR,Jagdeo J

更新日期：2019-03-20 00:00:00

abstract：:Mental health problems are highly prevalent in children and adolescents, but professional help-seeking behavior in this age group is extremely low. Therefore, the ProHEAD ("Promoting Help-seeking using E-technology for Adolescents") consortium focuses on three main objectives, i.e.: (1) improving young people's help-s...

journal_title：Trials

authors： Kaess M,Bauer S

更新日期：2019-01-22 00:00:00

abstract：BACKGROUND:Cancer is one of the major health issues worldwide. An increasing number of cancer patients are offered treatment with surgery, chemotherapy and radiotherapy. Traditional Chinese medicine (TCM) is one of the most common complementary therapies offered to cancer patients in Taiwan. We designed a randomized, d...

journal_title：Trials

authors： Lo LC,Chen CY,Chen ST,Chen HC,Lee TC,Chang CS

更新日期：2012-12-03 00:00:00

abstract：BACKGROUND:National obesity rates have dramatically risen over the last decade. Being obese significantly reduces life expectancy, increases the risk of a range of diseases, and compromises quality of life. Costs to both the National Health Service and society are high. An increased prevalence of obesity in people with...

journal_title：Trials

authors： Beeken RJ,Spanos D,Fovargue S,Hunter R,Omar R,Hassiotis A,King M,Wardle J,Croker H

更新日期：2013-03-12 00:00:00

abstract：BACKGROUND:Video-laryngoscopes are marketed for intubation in difficult airway management. They provide a better view of the larynx and may facilitate tracheal intubation, but there is no adequately powered study comparing different types of video-laryngoscopes in a difficult airway scenario or in a simulated difficult...

journal_title：Trials

authors： Theiler L,Hermann K,Schoettker P,Savoldelli G,Urwyler N,Kleine-Brueggeney M,Arheart KL,Greif R

更新日期：2013-04-04 00:00:00

abstract：BACKGROUND:Non-retention of participants seriously affects the credibility of clinical trial results and significantly reduces the potential of a trial to influence clinical practice. Non-retention can be defined as instances where participants leave the study prematurely. Examples include withdrawal of consent and los...

journal_title：Trials

authors： Gillies K,Bower P,Elliott J,MacLennan G,Newlands RSN,Ogden M,Treweek SP,Wells M,Witham MD,Young B,Francis JJ

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:The oversight and conduct of a randomised controlled trial involves several stakeholders, including a Trial Steering Committee (TSC), Trial Management Group (TMG), Data Monitoring Committee (DMC), funder and sponsor. We aimed to examine how the relationships between these stakeholders affect the trial oversi...

journal_title：Trials

authors： Daykin A,Selman LE,Cramer H,McCann S,Shorter GW,Sydes MR,Gamble C,Macefield R,Lane JA,Shaw A

更新日期：2017-12-22 00:00:00

abstract：BACKGROUND:Physical exercise interventions have been extensively advocated for the treatment of obesity; however, clinical trials evaluating the effectiveness of exercise interventions on weight control show controversial results. Compensatory mechanisms through a decrease in energy expenditure and/or an increase in ca...

journal_title：Trials

authors： Paravidino VB,Mediano MFF,Silva ICM,Wendt A,Del Vecchio FB,Neves FA,Terra BS,Gomes EAC,Moura AS,Sichieri R

更新日期：2018-03-07 00:00:00

abstract：BACKGROUND:Given the complex nature of opioid addiction treatment and the rising number of available opioid substitution and antagonist therapies (OSAT), there is no 'gold standard' measure of treatment effectiveness, and each successive trial measures a different set of outcomes which reflect success in arbitrary or o...

journal_title：Trials

authors： Dennis BB,Sanger N,Bawor M,Naji L,Plater C,Worster A,Woo J,Bhalerao A,Baptist-Mohseni N,Hillmer A,Rice D,Corace K,Hutton B,Tugwell P,Thabane L,Samaan Z

更新日期：2020-01-06 00:00:00

abstract：INTRODUCTION:End-of-life (EoL) care professionals are prone to burnout given the intense emotional nature of their work. Previous research supports the efficacy of art therapy in reducing work-related stress and enhancing emotional health among professional EoL caregivers. Integrating mindfulness meditation with art th...

journal_title：Trials

authors： Ho AHY,Tan-Ho G,Ngo TA,Ong G,Chong PH,Dignadice D,Potash J

更新日期：2019-07-08 00:00:00

abstract：BACKGROUND:In people with chronic obstructive pulmonary disease (COPD), limb-muscle dysfunction is one of the most troublesome systemic manifestations of the disease, which at the functional level is evidenced by reduced strength and endurance of limb muscles. Improving limb-muscle function is an important therapeutic ...

journal_title：Trials

authors： Frykholm E,Klijn P,Saey D,van Hees HWH,Stål P,Sandström T,Sörlin A,Maltais F,Nyberg A

更新日期：2019-01-03 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is reported by one in ten of the population accounting for up to 40% of new referrals to gastroenterology outpatients. Patients characteristically have abdominal discomfort and disturbed bowel habit. Diarrhoea-predominant IBS is characterised by frequent loose stools with assoc...

journal_title：Trials

authors： Leighton MP,Lam C,Mehta S,Spiller RC

更新日期：2013-01-09 00:00:00

abstract：OBJECTIVES:To assess the effect of prone positioning therapy on intubation rate in awake patients with COVID-19 and acute respiratory failure. TRIAL DESIGN:This is a two-center parallel group, superiority, randomized (1:1 allocation ratio) controlled trial. PARTICIPANTS:All patients admitted to the Hospital Civil de ...

journal_title：Trials

authors： Ibarra-Estrada MÁ,Marín-Rosales M,García-Salcido R,Aguirre-Díaz SA,Vargas-Obieta A,Chávez-Peña Q,López-Pulgarín JA,Mijangos-Méndez JC,Aguirre-Avalos G

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:The ability to retrieve specific memories is a cognitive and emotional protective factor. Among the most effective techniques to generate autobiographical memories is the use of audio-visual stimuli, particularly images. Developing and improving techniques that facilitate the generation of such memories coul...

journal_title：Trials

authors： Fernández D,Ros L,Sánchez-Reolid R,Ricarte JJ,Latorre JM

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:Post-dural puncture headache (PDPH) is one of the most common complications of neuraxial anaesthesia. It limits patients' general activity and increases the length of hospital stays and the use of care. It is particularly disabling during the postpartum period, when mothers have to take care of their child. ...

journal_title：Trials

authors： Depaulis C,Steer N,Garessus L,Chassard D,Aubrun F

更新日期：2020-01-08 00:00:00

abstract：BACKGROUND:The insertion of central venous access devices, such as totally implantable venous access ports (TIVAPs), is routine in patients who need a safe and permanent venous access. The number of port implantations is increasing due to the development of innovative adjuvant and neo-adjuvant therapies. Currently, two...

journal_title：Trials

authors： Hüttner FJ,Bruckner T,Alldinger I,Hennes R,Ulrich A,Büchler MW,Diener MK,Knebel P

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:Maintaining adequate oxygenation during rapid sequence intubation (RSI) is imperative to prevent peri-intubation adverse events that can lead to increased duration of hospital and intensive care unit stay, or a prolonged vegetative state requiring long-term institutionalisation. Despite employing current bes...

journal_title：Trials

authors： Chua MT,Khan FA,Ng WM,Lu Q,Low MJW,Yau YW,Punyadasa A,Kuan WS

更新日期：2019-04-04 00:00:00

abstract：:In October 2015 we published the paper 'Measurement of HbA1c in multicentre diabetes trials - should blood samples be tested locally or sent to a central laboratory: an agreement analysis'. Chatterjee and Pradhan have submitted a letter to the editor asking critical questions regarding the methods we used. We offer th...

journal_title：Trials

authors： Arch BN,Blair J,McKay A,Gregory JW,Newland P,Gamble C

更新日期：2017-05-26 00:00:00

abstract：BACKGROUND:Adolescent idiopathic scoliosis (AIS) is one of the most prevalent spinal deformities that may progress sharply during growth. The aim of this study will be to evaluate the efficacy of three-dimensionally integrated exercise on the Cobb angle, angle of trunk rotation, sagittal profile, and quality of life in...

journal_title：Trials

authors： Liang J,Zhou X,Chen N,Li X,Yu H,Yang Y,Song Y,Du Q

更新日期：2018-09-10 00:00:00

abstract：BACKGROUND:Failure to collect outcome data in randomised trials can result in bias and loss of statistical power. Further evaluations of strategies to increase retention are required. We assessed the effectiveness of two strategies for retention in a randomised prevention trial using a two-by-two factorial randomised s...

journal_title：Trials

authors： Bradshaw LE,Montgomery AA,Williams HC,Chalmers JR,Haines RH

更新日期：2020-06-08 00:00:00

abstract：BACKGROUND/AIMS:Prediabetes and diabetes disproportionately impact Latino youth, yet few diabetes prevention programs have prioritized inclusion of this underrepresented population. This report describes the recruitment process, yields, associated costs, and phenotypic characteristics of Latino youth with obesity and p...

journal_title：Trials

authors： Vander Wyst KB,Olson ML,Hooker E,Soltero EG,Konopken YP,Keller CS,Castro FG,Williams AN,Fernández ADR,Patrick DL,Ayers SL,Hu HH,Peña A,Pimentel J,Knowler WC,Shaibi GQ

更新日期：2020-08-14 00:00:00

abstract：BACKGROUND:Endovenous thermal techniques, such as endovenous laser ablation (EVLA), are the recommended treatment for truncal varicose veins. However, a disadvantage of thermal techniques is that it requires the administration of tumescent anaesthesia, which can be uncomfortable. Non-thermal, non-tumescent techniques, ...

journal_title：Trials

authors： Leung CC,Carradice D,Wallace T,Chetter IC

更新日期：2016-08-24 00:00:00

abstract：BACKGROUND:At least 40% of people with psychosis have persistent distressing symptoms despite optimal medication treatment. Cognitive behaviour therapy for psychosis (CBTp) is the only NICE-recommended individual therapy for psychosis, with effects on symptoms, distress and quality of life. Yet <10% of service-users re...

journal_title：Trials

authors： Greenwood K,Alford K,O'Leary I,Peters E,Hardy A,Cavanagh K,Field AP,de Visser R,Fowler D,Davies M,Papamichail A,Garety P

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:Metabolic acidosis is more common with advancing chronic kidney disease, and has been associated with impaired physical function, impaired bone health, accelerated decline in kidney function and increased vascular risk. Although oral sodium bicarbonate is widely used to correct metabolic acidosis, there exis...

journal_title：Trials

authors： Witham MD,Band MM,Littleford RC,Avenell A,Soiza RL,McMurdo ME,Sumukadas D,Ogston SA,Lamb EJ,Hampson G,McNamee P,BiCARB Study Group.

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:It is expected that in 2020 more than 17,000 cases of colorectal cancer will be diagnosed in The Netherlands. To date, patients are included in a surgeon-led follow-up programme whose main focus is recurrence detection. However, patients often experience multiple physical and psychosocial problems. Currently...

journal_title：Trials

authors： Duineveld LA,Wieldraaijer T,van Asselt KM,Nugteren IC,Donkervoort SC,van de Ven AW,Smits AB,van Geloven AA,Bemelman WA,Beverdam FH,van Tets WF,Govaert MJ,Bosmans JE,Verdonck-de Leeuw IM,van Uden-Kraan CF,van Weert HC,Wind

更新日期：2015-06-26 00:00:00

abstract：BACKGROUND:Cigarette smoking negatively impacts on maternal and fetal health. Smoking cessation is one of the few interventions capable of improving pregnancy outcomes. Despite the risks, the most effective antenatal model of care for smokers is still unclear, and specific recommendations for screening for fetal growth...

journal_title：Trials

authors： McDonnell BP,Dicker P,Keogan S,Clancy L,Regan C

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:The current randomized controlled trial seeks to evaluate whether providing access to an Internet intervention for problem drinking in addition to an Internet intervention for problem gambling is beneficial for participants with gambling problems who do or do not have co-occurring problem drinking. METHODS:...

journal_title：Trials

authors： Cunningham JA,Hodgins DC,Keough M,Hendershot CS,Bennett K,Bennett A,Godinho A

更新日期：2018-05-25 00:00:00

abstract：BACKGROUND:During clinical trials in emergency medicine, providing appropriate oral and written information to a patient is usually a challenge. There is little published information regarding patients' opinions and competence to provide informed consent, nor on physicians' attitudes towards the process. We have invest...

journal_title：Trials

authors： Iwanowski P,Budaj A,Członkowska A,Wasek W,Kozłowska-Boszko B,Oledzka U,Masełbas W

更新日期：2008-07-21 00:00:00

abstract：BACKGROUND:A wide range of prophylactic antibiotic regimens are used for patients undergoing open-heart cardiac surgery. This reflects clinical equipoise in choice and duration of antibiotic agents. Although individual-level randomized control trials (RCT) are considered the gold standard when evaluating the efficacy o...

journal_title：Trials

authors： van Oostveen RB,Romero-Palacios A,Whitlock R,Lee SF,Connolly S,Carignan A,Mazer CD,Loeb M,Mertz D

更新日期：2018-12-17 00:00:00

abstract：BACKGROUND:Depression accounts for the greatest burden of disease among all mental health problems, and is expected to become the second-highest amongst all general health problems by 2020. By the age of 75, 1 in 7 older people meet formal diagnostic criteria for depression. Efforts to ameliorate the burden of illness ...

journal_title：Trials

authors： Mitchell N,Hewitt C,Adamson J,Parrott S,Torgerson D,Ekers D,Holmes J,Lester H,McMillan D,Richards D,Spilsbury K,Godfrey C,Gilbody S

更新日期：2011-10-11 00:00:00