Online interventions for problem gamblers with and without co-occurring problem drinking: study protocol of a randomized controlled trial.

abstract：BACKGROUND:The German welfare system follows the principle "rehabilitation rather than pension," but more than the half of all disability pensioners did not utilize medical rehabilitation before their early retirement. A major barrier is the application procedure. Lack of information about the opportunity to utilize re...

journal_title：Trials

authors： Spanier K,Streibelt M,Ünalan F,Bethge M

更新日期：2015-09-29 00:00:00

abstract：BACKGROUND:Cigarette smoking negatively impacts on maternal and fetal health. Smoking cessation is one of the few interventions capable of improving pregnancy outcomes. Despite the risks, the most effective antenatal model of care for smokers is still unclear, and specific recommendations for screening for fetal growth...

journal_title：Trials

authors： McDonnell BP,Dicker P,Keogan S,Clancy L,Regan C

更新日期：2019-09-03 00:00:00

abstract：BACKGROUND:Verrucae are a common, infectious and sometimes painful problem. The optimal treatment for verrucae is unclear due to a lack of high quality randomised controlled trials. The primary objective of this study is to compare the clinical effectiveness of two common treatments for verrucae: cryotherapy using liqu...

journal_title：Trials

authors： Cockayne ES,EVERT Trial Team.

更新日期：2010-02-08 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) is one of the leading chronic inflammatory rheumatism. First-line therapy with synthetic disease-modifying antirheumatic drugs (sDMARD) is insufficiently effective in 40% of cases and these patients are treated with biotherapies. The increased use of these drugs each year is becomin...

journal_title：Trials

authors： Freites-Núñez D,Baillet A,Rodriguez-Rodriguez L,Nguyen MVC,Gonzalez I,Pablos JL,Balsa A,Vazquez M,Gaudin P,Fernandez-Gutierrez B

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:It is generally accepted that an active lifestyle is beneficial for cognition in children, adults and the elderly. Recently, studies using the rat animal model found that the pups of mothers who exercised during pregnancy had increased hippocampal neurogenesis and better memory and learning abilities. The ai...

journal_title：Trials

authors： LeMoyne EL,Curnier D,St-Jacques S,Ellemberg D

更新日期：2012-05-29 00:00:00

abstract：BACKGROUND:In rural Ethiopia, 72% of women are exposed to lifetime intimate partner violence (IPV); IPV is most prevalent during pregnancy. As well as adversely affecting women's physical and mental health, IPV also increases the risk of child morbidity and mortality associated with maternal depression, thus making ant...

journal_title：Trials

authors： Keynejad RC,Bitew T,Sorsdahl K,Myers B,Honikman S,Medhin G,Deyessa N,Sevdalis N,Tol WA,Howard L,Hanlon C

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:More than 60,000 people have health problems due to chemical weapons exposure during the Iran-Iraq war. Respiratory consequences of mustard gas exposure are common and disabling; medical interventions have limited effect. Patients complain of cough, sputum, breathlessness and exercise limitation. We hypothes...

journal_title：Trials

authors： Sedighi Moghadam MR,Ghanei M,Kenn K,Hopkinson NS

更新日期：2019-02-14 00:00:00

abstract：BACKGROUND:Granulomatosis with polyangiitis (GPA, Wegener's) and microscopic polyangiitis (MPA) are small vessel vasculitides collectively referred to as anti-neutrophil cytoplasm antibody-associated vasculitis (AAV). AAV is associated with high rates of morbidity and mortality due to uncontrolled disease and treatment...

journal_title：Trials

authors： Walsh M,Merkel PA,Peh CA,Szpirt W,Guillevin L,Pusey CD,De Zoysa J,Ives N,Clark WF,Quillen K,Winters JL,Wheatley K,Jayne D,PEXIVAS Investigators.

更新日期：2013-03-14 00:00:00

abstract：BACKGROUND:Cardiac surgery has been shown to result in a significant decrease of the antioxidant selenium, which is associated with the development of multiorgan dysfunction and increased mortality. Thus, a large-scale study is needed to investigate the effect of perioperative selenium supplementation on the occurrence...

journal_title：Trials

authors： Stoppe C,McDonald B,Rex S,Manzanares W,Whitlock R,Fremes S,Fowler R,Lamarche Y,Meybohm P,Haberthür C,Rossaint R,Goetzenich A,Elke G,Day A,Heyland DK

更新日期：2014-08-28 00:00:00

abstract：BACKGROUND:Carotid atherosclerosis disease (CAD) is generally associated with the occurrence of cardiovascular and cerebrovascular accidents. However, CAD has not been taken seriously enough in the clinic, which, coupled with the single treatment and prevention of CAD, has led to a generally low level of patient compli...

journal_title：Trials

authors： Zhou J,Zhao L,Meng L,Liang H,Zhou T,Ye S,Qi Z,Huang X,Zhou P,Fu W

更新日期：2020-09-07 00:00:00

abstract：:After publication of our article [1] the authors have notified us that one of the names has been incorrectly spelled. ...

journal_title：Trials

authors： Tegtmeier F,Schinzel R,Beer R,Bulters D,LeFrant JY,Sahuquillo J,Unterberg A,Andrews P,Belli A,Ibanez J,Lagares A,Mokry M,Willschke H,Flüh C,Schmutzhard E,NOSTRA Investigators.

更新日期：2020-02-12 00:00:00

abstract：BACKGROUND:Non-communicable chronic diseases are linked to behavioral risk factors (including smoking, poor diet and physical inactivity), so effective behavior change interventions are needed to improve population health. However, uptake and impact of these interventions is limited by methodological challenges. We aim...

journal_title：Trials

authors： Byrne M,McSharry J,Meade O,Lavoie KL,Bacon SL

更新日期：2020-03-23 00:00:00

abstract：BACKGROUND:The burden of chronic pain is a major challenge, impacting the quality of life of patients. Intensive programmes of mindfulness-based therapy can help patients to cope with chronic pain but can be time consuming and require a trained specialist to implement. The self-management model of care is now integral ...

journal_title：Trials

authors： Howarth A,Perkins-Porras L,Smith JG,Subramaniam J,Copland C,Hurley M,Beith I,Riaz M,Ussher M

更新日期：2016-06-02 00:00:00

abstract：BACKGROUND:Cardiovascular diseases are the major cause of death in the world. Current treatments have not been able to reverse this scenario, creating the need for the development of new therapies. Cell therapies have emerged as an alternative for cardiac diseases of distinct causes in experimental animal studies and m...

journal_title：Trials

authors： Tura BR,Martino HF,Gowdak LH,dos Santos RR,Dohmann HF,Krieger JE,Feitosa G,Vilas-Boas F,Oliveira SA,Silva SA,Bozza AZ,Borojevic R,de Carvalho AC

更新日期：2007-01-18 00:00:00

abstract：BACKGROUND:Hearing and vision impairments are highly prevalent in people with dementia and may have a negative impact on quality of life and other dementia-related outcomes. Intervening to optimise sensory impairment and support sensory function may be a means of improving dementia-related outcomes. The SENSE-Cog trial...

journal_title：Trials

authors： Regan J,Frison E,Collin F,Dawes P,Hann M,Himmelsbach I,Hooper E,Reeves D,Simkin Z,Thodi C,Yang F,Leroi I,SENSE-Cog Trial Development Team.

更新日期：2019-01-25 00:00:00

abstract：BACKGROUND:Evidence increases that a high or a standard dose of tranexamic acid (TA) reduces postpartum bleeding. The TRACES pharmacobiological substudy aims to establish a therapeutic strategy in hemorrhagic (H) Cesarean section (CS) with respect to the intensity of fibrinolysis by using innovative assays. METHOD/DES...

journal_title：Trials

authors： Ducloy-Bouthors AS,Jeanpierre E,Saidi I,Baptiste AS,Simon E,Lannoy D,Duhamel A,Allorge D,Susen S,Hennart B

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:There is considerable evidence showing that injured people who are involved in a compensation process show poorer physical and mental recovery than those with similar injuries who are not involved in a compensation process. One explanation for this reduced recovery is that the legal process and the associate...

journal_title：Trials

authors： Elbers NA,Akkermans AJ,Cuijpers P,Bruinvels DJ

更新日期：2013-07-20 00:00:00

abstract：BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia is a serious infection resulting in 20-50 % 90-day mortality. The limitations of vancomycin, the current standard therapy for MRSA, make treatment difficult. The only other approved drug for treatment of MRSA bacteraemia, daptomycin, has not been...

journal_title：Trials

authors： Tong SY,Nelson J,Paterson DL,Fowler VG Jr,Howden BP,Cheng AC,Chatfield M,Lipman J,Van Hal S,O'Sullivan M,Robinson JO,Yahav D,Lye D,Davis JS,CAMERA2 study group and the Australasian Society for Infectious Diseases Clinical Res

更新日期：2016-03-31 00:00:00

abstract：BACKGROUND:Chronic lymphocytic leukaemia (CLL) is the most common adult leukaemia. Combination immunochemotherapy such as fludarabine, cyclophosphamide and rituximab is the standard first line therapy in fit patients, but there is limited evidence regarding the optimal treatment of patients after relapse. Ofatumumab as...

journal_title：Trials

authors： Howard DR,Munir T,Hockaday A,Rawstron AC,Collett L,Oughton JB,Allsup D,Bloor A,Phillips D,Hillmen P

更新日期：2016-09-20 00:00:00

abstract：BACKGROUND:Increasing numbers of patients are surviving critical illness, but survival may be associated with a constellation of physical and psychological sequelae that can cause ongoing disability and reduced health-related quality of life. Limited evidence currently exists to guide the optimum structure, timing, and...

journal_title：Trials

authors： Ramsay P,Salisbury LG,Merriweather JL,Huby G,Rattray JE,Hull AM,Brett SJ,Mackenzie SJ,Murray GD,Forbes JF,Walsh TS,RECOVER trial collaboration.

更新日期：2014-01-29 00:00:00

abstract：BACKGROUND:Practicing activities improves recovery after stroke, but many people in hospital do little activity. Feedback on activity using an accelerometer is a potential method to increase activity in hospital inpatients. This study's goal is to investigate the effect of feedback, enabled by a Smart watch, on daily p...

journal_title：Trials

authors： Dong Y,Steins D,Sun S,Li F,Amor JD,James CJ,Xia Z,Dawes H,Izadi H,Cao Y,Wade DT,Smart watch activity feedback trial committee (SWAFT).

更新日期：2018-03-09 00:00:00

abstract：BACKGROUND:Psychosis is a serious mental illness that typically emerges during early adulthood. The disorder is characterized by inactivity, cognitive deficits and the need for ongoing support. Regular exercise has mood enhancing and anxiolytic effects that could benefit this patient group. To date, few studies have ex...

journal_title：Trials

authors： Forsell Y,Hallgren M,Mattson M,Ekblom O,Lavebratt C

更新日期：2015-12-04 00:00:00

abstract：BACKGROUND:Post-dural puncture headache (PDPH) is one of the most common complications of neuraxial anaesthesia. It limits patients' general activity and increases the length of hospital stays and the use of care. It is particularly disabling during the postpartum period, when mothers have to take care of their child. ...

journal_title：Trials

authors： Depaulis C,Steer N,Garessus L,Chassard D,Aubrun F

更新日期：2020-01-08 00:00:00

abstract：BACKGROUND:Approximately 50% of heart failure patients are readmitted to hospital within 6 months, owing to deterioration of their condition. Thus, symptomatic treatment of heart failure requires significant improvement. The aim of this study is to compare the effects of torasemide and furosemide on biochemical paramet...

journal_title：Trials

authors： Balsam P,Ozierański K,Tymińska A,Główczyńska R,Peller M,Fojt A,Cacko A,Sieradzki B,Bakuła E,Markulis M,Kowalik R,Huczek Z,Filipiak KJ,Opolski G,Grabowski M

更新日期：2017-01-23 00:00:00

abstract：BACKGROUND:Frozen shoulder (FS) is a musculoskeletal condition of poorly understood etiology that results in shoulder pain and large mobility deficits. Despite some physical therapy interventions, such as joint mobilization and exercise, having shown therapeutic benefit, a definitive treatment does not currently exist....

journal_title：Trials

authors： Lluch-Girbés E,Dueñas L,Mena-Del Horno S,Luque-Suarez A,Navarro-Ledesma S,Louw A

更新日期：2019-08-13 00:00:00

abstract：BACKGROUND:Maori, the indigenous people of New Zealand, who present to hospital after intentionally harming themselves, do so at a higher rate than non-Maori. There have been no previous treatment trials in Maori who self harm and previous reviews of interventions in other populations have been inconclusive as existing...

journal_title：Trials

authors： Hatcher S,Coupe N,Durie M,Elder H,Tapsell R,Wikiriwhi K,Parag V

更新日期：2011-05-11 00:00:00

abstract：BACKGROUND:Respiratory support following postoperative extubation is of major importance to prevent hypoxemia and subsequent respiratory failure and reintubation. High-flow nasal cannula oxygen (HFNC) delivers a flow-dependent positive airway pressure and improves oxygenation by increasing end-expiratory lung volume. W...

journal_title：Trials

authors： Futier E,Paugam-Burtz C,Constantin JM,Pereira B,Jaber S

更新日期：2013-10-18 00:00:00

abstract：BACKGROUND:Neurofeedback has been applied effectively in various areas, especially in the treatment of children with attention-deficit/hyperactivity disorder (ADHD). This study protocol is designed to investigate the effect of slow cortical potential (SCP) feedback and a new form of neurofeedback using near-infrared sp...

journal_title：Trials

authors： Mayer K,Wyckoff SN,Fallgatter AJ,Ehlis AC,Strehl U

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:The management of patients with angiographically intermediate coronary lesions is a major clinical issue. Fractional flow reserve provides validated functional insights while optical coherence tomography provides high resolution anatomic imaging. Both techniques may be applied to guide management in case of ...

journal_title：Trials

authors： Burzotta F,Leone AM,De Maria GL,Niccoli G,Coluccia V,Pirozzolo G,Saffioti S,Aurigemma C,Trani C,Crea F

更新日期：2014-04-23 00:00:00

abstract：BACKGROUND:A high intake of salt is a major risk factor for cardiovascular diseases. Despite decades of effort to reduce salt consumption, the salt intake in China is still considerably above the recommended level. Thus, this study aims to design and implement an intelligent household added salt monitoring system (SALT...

journal_title：Trials

authors： Xian J,Zeng M,Zhu R,Cai Z,Shi Z,Abdullah AS,Zhao Y

更新日期：2020-04-21 00:00:00