Smoking cessation Through Optimisation of clinical care in Pregnancy: the STOP randomised controlled trial.

abstract：BACKGROUND:Acupuncture is a widely serviced complementary medicine. Although acupuncture is suggested for managing postoperative ileus and pain, supporting evidence is weak. The AcuLap trial is designed to provide high-level evidence regarding whether or not electroacupuncture is effective in promoting gastrointestinal...

journal_title：Trials

authors： Kim G

更新日期：2015-10-14 00:00:00

abstract：:Following the South African case, Treatment Action Campaign and Others v Minister of Health and Others, the use of 'pilot' studies to investigate interventions already proven efficacious, offered free of charge to government, but confined by the government to a small part of the population, may violate children's righ...

journal_title：Trials

authors： Oduwo E,Edwards SJ

更新日期：2014-07-16 00:00:00

abstract：BACKGROUND:With a survival rate of 6 to 11%, out-of-hospital cardiac arrest (OHCA) remains a healthcare challenge with room for improvement in morbidity and mortality. The guidelines emphasize the highest possible quality of cardiopulmonary resuscitation (CPR) and chest compressions (CC). It is essential to minimize CC...

journal_title：Trials

authors： Buléon C,Parienti JJ,Morilland-Lecoq E,Halbout L,Cesaréo E,Dubien PY,Jardel B,Boyer C,Husson K,Andriamirado F,Benet X,Morel-Marechal E,Aubrion A,Muntean C,Dupire E,Roupie E,Hubert H,Vilhelm C,Gueugniaud PY,CILICA-HS

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a common disease, associated with cardiovascular disease. Many patients use (long-acting) bronchodilators, whilst they continue smoking alongside. We hypothesised an interaction between bronchodilators and smoking that enhances smoke exposure, and hence cardiov...

journal_title：Trials

authors： van Dijk WD,Scheepers PT,Cremers R,Lenders JW,Klerx W,van Weel C,Schermer TR,Heijdra Y

更新日期：2011-02-10 00:00:00

abstract：:Periconceptional supplementation could extend the period over which maternal and fetal nutrition is improved, but there are many challenges facing early-life intervention studies. Periconceptional trials differ from pregnancy supplementation trials, not only because of the very early or pre-gestational timing of nutri...

journal_title：Trials

authors： Brabin BJ,Gies S,Owens S,Claeys Y,D'Alessandro U,Tinto H,Brabin L

更新日期：2016-01-30 00:00:00

abstract：BACKGROUND:Post-stroke depression (PSD) is the most common psychiatric complication after a stroke. The most frequently used antidepressants are selective serotonin receptor inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), however, these exhibit a series of side effects. Traditional Chin...

journal_title：Trials

authors： Zhao AM,Qiu WR,Mao LJ,Ren JG,Xu L,Yao MJ,Bilinksi K,Chang D,Liu JX

更新日期：2018-05-10 00:00:00

abstract：OBJECTIVES:To determine if lopinavir/ritonavir +/- hydroxychloroquine will reduce the proportion of participants who survive without requiring ventilatory support, 15 days after enrolment, in adult participants with non-critically ill SARS-CoV-2 infection. TRIAL DESIGN:ASCOT is an investigator-initiated, multi-centre,...

journal_title：Trials

authors： Denholm JT,Davis J,Paterson D,Roberts J,Morpeth S,Snelling T,Zentner D,Rees M,O'Sullivan M,Price D,Bowen A,Tong SYC,ASCOT Investigator Group.

更新日期：2020-07-14 00:00:00

abstract：BACKGROUND:Post-dural puncture headache (PDPH) is one of the most common complications of neuraxial anaesthesia. It limits patients' general activity and increases the length of hospital stays and the use of care. It is particularly disabling during the postpartum period, when mothers have to take care of their child. ...

journal_title：Trials

authors： Depaulis C,Steer N,Garessus L,Chassard D,Aubrun F

更新日期：2020-01-08 00:00:00

abstract：BACKGROUND:Acupuncture has been widely applied in the clinic to treat irritable bowel syndrome (IBS), but the underlying mechanism remains unknown. Diffuse noxious inhibitory control (DNIC) is deficient in patients with IBS, which attenuates the systemic analgesic effect elicited by noxious stimulation that is remote f...

journal_title：Trials

authors： Peng Y,You H,Chen X,Chen Y,Yang Y,Huang J,Xu N,Liu J

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:Postoperative delirium (POD) is a manifestation of acute postoperative brain dysfunction that is frequently observed after cardiac surgery. POD is associated with short-term complications such as an increase in mortality, morbidity, costs and length of stay, but can also have long-term sequelae, including pe...

journal_title：Trials

authors： Al Tmimi L,Van de Velde M,Herijgers P,Meyns B,Meyfroidt G,Milisen K,Fieuws S,Coburn M,Poesen K,Rex S

更新日期：2015-10-09 00:00:00

abstract：BACKGROUND:Low back pain is a common, disabling musculoskeletal disorder in both developing and developed countries. Although often recommended, the potential efficacy of massage therapy in general, and Chinese massage (tuina) in particular, for relief of chronic low back pain (CLBP) has not been fully established due ...

journal_title：Trials

authors： Yang M,Feng Y,Pei H,Deng S,Wang M,Xiao X,Zheng H,Lai Z,Chen J,Li X,He X,Liang F

更新日期：2014-10-29 00:00:00

abstract：BACKGROUND:Current international guidelines recommend the use of a daily topical exit-site antimicrobial to prevent peritoneal dialysis (PD)-related infections. Although nonantibiotic-based therapies are appealing because they may limit antimicrobial resistance, no controlled trials have been conducted to compare topic...

journal_title：Trials

authors： Nochaiwong S,Ruengorn C,Noppakun K,Panyathong S,Dandecha P,Sood MM,Saenjum C,Awiphan R,Sirilun S,Mongkhon P,Chongruksut W,Thavorn K,Thai Renal Outcomes Research (THOR) Investigators.

更新日期：2019-12-19 00:00:00

abstract：BACKGROUND:AirSeal is a novel class of valve-free insufflation system that enables a stable pneumoperitoneum with continuous smoke evacuation and carbon dioxide (CO₂) recirculation during laparoscopic surgery. Comparison data to standard CO₂ pressure pneumoperitoneum insufflators is scarce. The aim of this study is to ...

journal_title：Trials

authors： Luketina RR,Knauer M,Köhler G,Koch OO,Strasser K,Egger M,Emmanuel K

更新日期：2014-06-20 00:00:00

abstract：BACKGROUND:Effective programs to help children manage their weight are required. Families for Health focuses on a parenting approach, designed to help parents develop their parenting skills to support lifestyle change within the family. Families for Health V1 showed sustained reductions in overweight after 2 years in a...

journal_title：Trials

authors： Robertson W,Stewart-Brown S,Stallard N,Petrou S,Griffiths F,Thorogood M,Simkiss D,Lang R,Reddington K,Poole F,Rye G,Khan KA,Hamborg T,Kirby J

更新日期：2013-03-20 00:00:00

abstract：BACKGROUND:The incidence of strokes in industrialized nations is on the rise, particularly in the older population. In Canada, a minority of individuals who have had a stroke actually receive intensive rehabilitation because most stroke patients do not have access to services or because their motor recovery was judged ...

journal_title：Trials

authors： Tousignant M,Corriveau H,Kairy D,Berg K,Dubois MF,Gosselin S,Swartz RH,Boulanger JM,Danells C

更新日期：2014-01-30 00:00:00

abstract：BACKGROUND:This study protocol evaluates the effectiveness of adjuvant electroacupuncture (EA) for urinary retention in poststroke patients undergoing conventional treatments, in comparison with that of a sham control. METHODS/DESIGN:A multicenter, blinded, randomized controlled trial will be conducted in three hospit...

journal_title：Trials

authors： Shin S,Lee J,Yoo J,Lim SM,Lee E

更新日期：2016-04-12 00:00:00

abstract：BACKGROUND:Bone graft substitutes are widely used for reconstruction of posttraumatic bone defects. However, their clinical significance in comparison to autologous bone grafting, the gold-standard in reconstruction of larger bone defects, still remains under debate. This prospective, randomized, controlled clinical st...

journal_title：Trials

authors： Nusselt T,Hofmann A,Wachtlin D,Gorbulev S,Rommens PM

更新日期：2014-03-08 00:00:00

abstract：BACKGROUND:Patients with testicular germ cell cancer (GCC) have a high cure rate; however, cancer-related fatigue is the most common complication among patients with GCC undergoing treatment with chemotherapy. Although exercise is widely recommended, information about the physio-pathological effects of cancer therapy o...

journal_title：Trials

authors： Cuesta-Vargas AI,Carabantes F,Caracuel Z,Conejo I,Alba E

更新日期：2016-01-05 00:00:00

abstract：BACKGROUND:People with allergic rhinitis (AR) often seek help from Chinese medicine due to dissatisfaction with conventional treatments. Lung-spleen qi deficiency syndrome (LSQDS) is the most common type of AR, and the Chinese herbal medicine formula bi min fang (BMF) is commonly prescribed for AR patients with LSQDS. ...

journal_title：Trials

authors： Luo Q,Zhou S,Li X,Chen Q,Lin W,Lu L,Li H,Chen C,Chen W,Li Y

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:Sexual dysfunction can have a negative impact on women's quality of life and relationships. There is limited information about female sexual function and treatment, particularly during pregnancy and the postpartum period. The effect of pelvic floor muscle exercise (PFME) on sexual function (SF) has not been ...

journal_title：Trials

authors： Sobhgol SS,Priddis H,Smith CA,Dahlen HG

更新日期：2019-02-20 00:00:00

abstract：BACKGROUND:There has been longstanding interesting in cognitive training for older adults with cognitive impairment. In this study, we will investigate the effects of working memory training, and explore augmentation strategies that could possibly consolidate the effects in older adults with mild neurocognitive disorde...

journal_title：Trials

authors： Cheng CP,Chan SS,Mak AD,Chan WC,Cheng ST,Shi L,Wang D,Lam LC

更新日期：2015-10-24 00:00:00

abstract：BACKGROUND:Angulated fractures of the distal forearm are very frequent lesions in childhood. Currently, there are no standard guidelines on whether these children should be treated conservatively with a cast; with reduction and a cast; or with reduction, pinning and a cast under anesthesia. Minor prospective and retros...

journal_title：Trials

authors： Adrian M,Wachtlin D,Kronfeld K,Sommerfeldt D,Wessel LM

更新日期：2015-09-30 00:00:00

abstract：BACKGROUND:Juvenile dermatomyositis (JDM) is a rare autoimmune inflammatory disorder associated with significant morbidity and mortality. International collaboration is necessary to better understand the pathogenesis of the disease, response to treatment and long-term outcome. To aid international collaboration, it is ...

journal_title：Trials

authors： McCann LJ,Kirkham JJ,Wedderburn LR,Pilkington C,Huber AM,Ravelli A,Appelbe D,Williamson PR,Beresford MW

更新日期：2015-06-12 00:00:00

abstract：BACKGROUND:Stroke is a common cause of cognitive impairment and dementia. However, effective strategies for reducing the risk of post-stroke dementia remain undefined. Potential strategies include intensive lowering of blood pressure and/or lipids. METHODS/DESIGN: DESIGN:multi-centre prospective randomised open-label...

journal_title：Trials

authors： Blackburn DJ,Krishnan K,Fox L,Ballard C,Burns A,Ford GA,Mant J,Passmore P,Pocock S,Reckless J,Sprigg N,Stewart R,Wardlaw J,Bath PM

更新日期：2013-11-22 00:00:00

abstract：BACKGROUND:To prevent clinical relapse in teenagers with inflammatory bowel disease (IBD) there is a need to monitor disease activity continuously. Timely optimisation of medical treatment may nip a preclinical relapse in the bud and change the natural course of IBD. Traditionally, disease monitoring is done during sch...

journal_title：Trials

authors： Heida A,Dijkstra A,Groen H,Muller Kobold A,Verkade H,van Rheenen P

更新日期：2015-06-16 00:00:00

abstract：BACKGROUND:Neurofeedback has been applied effectively in various areas, especially in the treatment of children with attention-deficit/hyperactivity disorder (ADHD). This study protocol is designed to investigate the effect of slow cortical potential (SCP) feedback and a new form of neurofeedback using near-infrared sp...

journal_title：Trials

authors： Mayer K,Wyckoff SN,Fallgatter AJ,Ehlis AC,Strehl U

更新日期：2015-04-18 00:00:00

abstract：OBJECTIVES:Primary Objective: To determine the feasibility of delivering a protocolised, remote, online, Eye Movement Desensitisation and Reprocessing (EMDR) intervention, within 12-weeks of hospital discharge, for adult survivors of Covid-19 related critical illness. Secondary objectives: To investigate whether remote...

journal_title：Trials

authors： Bates A,Rushbrook S,Shapiro E,Grocott M,Cusack R

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:There is evidence to suggest that delivery of diabetes self-management support by diabetes educators in primary care may improve patient care processes and patient clinical outcomes; however, the evaluation of such a model in primary care is nonexistent in Canada. This article describes the design for the ev...

journal_title：Trials

authors： Gucciardi E,Fortugno M,Horodezny S,Lou W,Sidani S,Espin S,Webster F,Shah BR

更新日期：2012-09-13 00:00:00

abstract：BACKGROUND:Microvascular obstruction (MVO) secondary to ischaemic-reperfusion injury is an important but underappreciated determinant of short- and longer-term outcome following percutaneous coronary intervention (PCI) treatment of ST-elevation myocardial infarction (STEMI). Several small studies have demonstrated a re...

journal_title：Trials

authors： Nazir SA,Khan JN,Mahmoud IZ,Greenwood JP,Blackman DJ,Kunadian V,Been M,Abrams KR,Wilcox R,Adgey AA,McCann GP,Gershlick AH

更新日期：2014-09-25 00:00:00

abstract：BACKGROUND:Same-sex attracted young adults have been found to experience higher rates of mental health problems and greater difficulties in accessing specialist mental health care services compared to their heterosexual peers. Internet-based mental health interventions have the potential to be more engaging and accessi...

journal_title：Trials

authors： Abbott JA,Klein B,McLaren S,Austin DW,Molloy M,Meyer D,McLeod B

更新日期：2014-12-23 00:00:00