Neurofeedback as a nonpharmacological treatment for adults with attention-deficit/hyperactivity disorder (ADHD): study protocol for a randomized controlled trial.

abstract：BACKGROUND:The success of a clinical trial is often dependant on whether recruitment targets can be met in the required time frame. Despite an increase in research into the benefits of exercise in people with multiple sclerosis (PwMS), no trial has reported detailed data on effective recruitment strategies for large-sc...

journal_title：Trials

authors： Carter A,Humphreys L,Snowdon N,Sharrack B,Daley A,Petty J,Woodroofe N,Saxton J

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:Osteoarthritis (OA) is the most prevalent chronic joint disease, characterized by joint structural deterioration, pain and loss of function among the elders. It is also associated with several extra-articular symptoms (fatigue, sleep disorders, anxiety and depression) and a reduction of life quality. Studies...

journal_title：Trials

authors： Huang Z,Pan X,Deng W,Huang Z,Huang Y,Huang X,Zhu Z,Han W,Zheng S,Guo X,Ding C,Li T

更新日期：2018-04-17 00:00:00

abstract：BACKGROUND:Cognitive behaviour therapy (CBT) is an effective treatment for depression. However, CBT is a complex therapy that requires highly trained and qualified practitioners, and its scalability is therefore limited by the costs of training and employing sufficient therapists to meet demand. Behavioural activation ...

journal_title：Trials

authors： Rhodes S,Richards DA,Ekers D,McMillan D,Byford S,Farrand PA,Gilbody S,Hollon SD,Kuyken W,Martell C,O'Mahen HA,O'Neill E,Reed N,Taylor RS,Watkins ER,Wright KA

更新日期：2014-01-21 00:00:00

abstract：BACKGROUND:During leisure activities young people are often exposed to excessive noise levels resulting in an increase of noise-induced symptoms such as hearing loss, tinnitus and hyperacusis. Noise-induced tinnitus is often perceived after loud music exposure and provides an important marker for overexposure as a temp...

journal_title：Trials

authors： Gilles A,Ihtijarevic B,Wouters K,Van de Heyning P

更新日期：2014-04-05 00:00:00

abstract：BACKGROUND:Beneficial effects of placebos are high in double-blind hot flush trials. Studies in various conditions suggest that honestly prescribed placebos may elicit symptom improvement. OBJECTIVE:To determine whether open label placebo (OLP) treatment is efficacious in alleviating hot flushes among peri- and postme...

journal_title：Trials

authors： Pan Y,Meister R,Löwe B,Winkelmann A,Kaptchuk TJ,Buhling KJ,Nestoriuc Y

更新日期：2019-08-16 00:00:00

abstract：BACKGROUND:Evidence increases that a high or a standard dose of tranexamic acid (TA) reduces postpartum bleeding. The TRACES pharmacobiological substudy aims to establish a therapeutic strategy in hemorrhagic (H) Cesarean section (CS) with respect to the intensity of fibrinolysis by using innovative assays. METHOD/DES...

journal_title：Trials

authors： Ducloy-Bouthors AS,Jeanpierre E,Saidi I,Baptiste AS,Simon E,Lannoy D,Duhamel A,Allorge D,Susen S,Hennart B

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Preterm birth accounts for 75% of perinatal deaths and more than 50% of long-term neurological disabilities. For a singleton pregnancy, progesterone treatment is effective in prevention of preterm birth in women with an asymptomatic short cervix or a history of preterm birth. However, a large proportion of p...

journal_title：Trials

authors： Cheung KW,Seto MTY,Ng EHY

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:Post-stroke depression (PSD) is the most common psychiatric complication after a stroke. The most frequently used antidepressants are selective serotonin receptor inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), however, these exhibit a series of side effects. Traditional Chin...

journal_title：Trials

authors： Zhao AM,Qiu WR,Mao LJ,Ren JG,Xu L,Yao MJ,Bilinksi K,Chang D,Liu JX

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:Announcements of interim analyses of a clinical trial convey information about the results beyond the trial's Data Safety Monitoring Board (DSMB). The amount of information conveyed may be minimal, but the fact that none of the trial's stopping boundaries has been crossed implies that the experimental therap...

journal_title：Trials

authors： Broglio KR,Stivers DN,Berry DA

更新日期：2014-03-07 00:00:00

abstract：BACKGROUND:Published evaluations of successful interventions to prevent falls in people with sight impairment (SI) are limited. The aim of this feasibility study is to optimise the design and investigation of home safety (HS) and home exercise (HE) programmes to prevent falls in older people with SI. METHODS:A communi...

journal_title：Trials

authors： Waterman H,Ballinger C,Brundle C,Chastin S,Gage H,Harper R,Henson D,Laventure B,McEvoy L,Pilling M,Olleveant N,Skelton DA,Stanford P,Todd C

更新日期：2016-09-26 00:00:00

abstract：BACKGROUND:Real-time functional magnetic resonance imaging (rtfMRI) is used for neurofeedback training (NFT). Preliminary results suggest that it can help patients to control their symptoms. This study uses rtfMRI NFT for relapse prevention in alcohol dependence. METHODS/DESIGN:Participants are alcohol-dependent patie...

journal_title：Trials

authors： Cox WM,Subramanian L,Linden DE,Lührs M,McNamara R,Playle R,Hood K,Watson G,Whittaker JR,Sakhuja R,Ihssen N

更新日期：2016-10-03 00:00:00

abstract：BACKGROUND:Liver failure patients have traditionally been empirically transfused prior to invasive procedures. Blood transfusion is associated with immunologic and nonimmunologic reactions, increased risk of adverse outcomes and high costs. Scientific evidence supporting empirical transfusion is lacking, and the best a...

journal_title：Trials

authors： Rocha LL,Pessoa CM,Neto AS,do Prado RR,Silva E,de Almeida MD,Correa TD,POCKET Trial Investigators.

更新日期：2017-02-27 00:00:00

abstract：BACKGROUND:Loneliness in older people is associated with poor health-related quality of life (HRQoL). We undertook a parallel-group randomised controlled trial to evaluate the effectiveness and cost-effectiveness of telephone befriending for the maintenance of HRQoL in older people. An internal pilot tested the feasibi...

journal_title：Trials

authors： Mountain GA,Hind D,Gossage-Worrall R,Walters SJ,Duncan R,Newbould L,Rex S,Jones C,Bowling A,Cattan M,Cairns A,Cooper C,Edwards RT,Goyder EC

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:The logrank test is routinely applied to design and analyse randomized controlled trials (RCTs) with time-to-event outcomes. Sample size and power calculations assume the treatment effect follows proportional hazards (PH). If the PH assumption is false, power is reduced and interpretation of the hazard ratio...

journal_title：Trials

authors： Royston P,B Parmar MK

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Although conventional laparoscopic and hand-assisted laparoscopic surgery for colorectal cancer is widely used today, there remain many technical challenges especially for right colon cancer in obese patients. Herein, we develop a novel hand-assisted laparoscopic surgery (HALS) with complete mesocolic excisi...

journal_title：Trials

authors： Yang X,Wu Q,Jin C,He W,Wang M,Yang T,Wei M,Deng X,Meng W,Wang Z

更新日期：2017-07-26 00:00:00

abstract：BACKGROUND:People with allergic rhinitis (AR) often seek help from Chinese medicine due to dissatisfaction with conventional treatments. Lung-spleen qi deficiency syndrome (LSQDS) is the most common type of AR, and the Chinese herbal medicine formula bi min fang (BMF) is commonly prescribed for AR patients with LSQDS. ...

journal_title：Trials

authors： Luo Q,Zhou S,Li X,Chen Q,Lin W,Lu L,Li H,Chen C,Chen W,Li Y

更新日期：2019-01-18 00:00:00

abstract：BACKGROUND:As the toxicity associated with the α-GalCer-pulsed dendritic cell (DC) therapy could be considered to be negligible, its addition to postoperative adjuvant chemotherapy would be expected to greatly improve the therapeutic effect, and could result in prolonged survival. The aim of the present study is to com...

journal_title：Trials

authors： Saka H,Kitagawa C,Ichinose Y,Takenoyama M,Ibata H,Kato T,Takami K,Yamashita M,Maeda T,Takeo S,Ueda H,Okabayashi K,Nagashima S,Oka T,Kouso H,Fukuyama S,Yoshimoto K,Shimokawa M,Saito AM,Ito S

更新日期：2017-09-15 00:00:00

abstract：OBJECTIVES:Primary Objective: To determine the feasibility of delivering a protocolised, remote, online, Eye Movement Desensitisation and Reprocessing (EMDR) intervention, within 12-weeks of hospital discharge, for adult survivors of Covid-19 related critical illness. Secondary objectives: To investigate whether remote...

journal_title：Trials

authors： Bates A,Rushbrook S,Shapiro E,Grocott M,Cusack R

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:Recently, catheter-based renal sympathetic denervation (RSD) has been verified to be safely used to substantially reduce the levels of blood pressure, left ventricular hypertrophy, sleep apnea severity and norepinephrine spillover, and improve glucose tolerance. All these pathological changes are recognized ...

journal_title：Trials

authors： Qiu M,Yin Y,Shan Q

更新日期：2013-06-11 00:00:00

abstract：BACKGROUND:Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries. Inappropriate empiric antimicrobial treatment is associated with increased mortality. In this context...

journal_title：Trials

authors： Rosso-Fernández C,Garnacho-Montero J,Antonelli M,Dimopoulos G,Cisneros JM,MagicBullet study group.

更新日期：2015-03-20 00:00:00

abstract：BACKGROUND:Unhealthy alcohol use is a leading cause of morbidity and mortality among young people, including university students. Delivering secondary prevention interventions against unhealthy alcohol use is challenging. Information technology has the potential to reach large parts of the general population. The prese...

journal_title：Trials

authors： Bertholet N,Schmutz E,Grazioli VS,Faouzi M,McNeely J,Gmel G,Daeppen JB,Cunningham JA

更新日期：2020-02-17 00:00:00

abstract：BACKGROUND:Adolescent idiopathic scoliosis (AIS) is one of the most prevalent spinal deformities that may progress sharply during growth. The aim of this study will be to evaluate the efficacy of three-dimensionally integrated exercise on the Cobb angle, angle of trunk rotation, sagittal profile, and quality of life in...

journal_title：Trials

authors： Liang J,Zhou X,Chen N,Li X,Yu H,Yang Y,Song Y,Du Q

更新日期：2018-09-10 00:00:00

abstract：BACKGROUND:Enrollment in interventional therapeutic clinical trials is a small fraction of all patients who might participate given reasonable access. METHODS:A hierarchical approach is utilized in measuring staged participation from trial availability to patient enrollment. Our framework suggests that concern for jus...

journal_title：Trials

authors： Kanarek NF,Kanarek MS,Olatoye D,Carducci MA

更新日期：2012-12-10 00:00:00

abstract：BACKGROUND:Intrathecally administered morphine is effective as part of a postoperative analgesia regimen following major hepatopancreaticobiliary surgery. However, the potential for postoperative respiratory depression at the doses required for effective analgesia currently limits its clinical use. The use of a low-dos...

journal_title：Trials

authors： Cosgrave D,Galligan M,Soukhin E,McMullan V,McGuinness S,Puttappa A,Conlon N,Boylan J,Hussain R,Doran P,Nichol A

更新日期：2017-12-29 00:00:00

abstract：BACKGROUND:Generalized anxiety disorder (GAD) is a psychiatric disorder characterized by a constant and unspecific anxiety that interferes with daily-life activities. Its high prevalence in general population and the severe limitations it causes, point out the necessity to find new efficient strategies to treat it. Tog...

journal_title：Trials

authors： Gorini A,Riva G

更新日期：2008-05-05 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) is one of the most common types of the cardiovascular disease. Previous pilot trials have suggested that Traditional Chinese Medicine (TCM) has brought clinical benefits for patients with CAD. We will conduct this trial to determine the efficacy and safety of Shenzhu Guanxin Rec...

journal_title：Trials

authors： Jin X,Pan B,Wu H,Wu B,Li Y,Wang X,Liu G,Dang X,Xu D

更新日期：2019-08-20 00:00:00

abstract：BACKGROUND:Basal cell carcinoma is the most common skin cancer worldwide. Treatment options include both surgical and topical modalities. Although risk of metastasis is low, basal cell carcinoma can be invasive and infiltrate important underlying structures such as bone or cartilage. While many clinical trials examinin...

journal_title：Trials

authors： Schlessinger DI,Iyengar S,Yanes AF,Lazaroff JM,Godinez-Puig V,Chen BR,Kurta AO,Henley JK,Chiren SG,Furlan KC,Schmitt J,Deckert S,Poon E,Sobanko JF,Cartee TV,Alam M,Maher IA

更新日期：2017-10-23 00:00:00

abstract：BACKGROUND:Less invasive surfactant administration (LISA) is a way of giving surfactant without endotracheal intubation and has shown to be promising in reducing the incidence of bronchopulmonary dysplasia (BPD) in preterm infants. However, the mechanism underlying its beneficial effect and variations in the technique ...

journal_title：Trials

authors： Zhu J,Bao Y,Du L,Huang H,Lv Q,Jiang Y,Dai Y,Chen Z,Shi J,Shi Y,Yang C,Mei H,Jiang H,Sun Y,Sun X

更新日期：2020-06-11 00:00:00

abstract：BACKGROUND:Patients with type 2 diabetes (T2DM) are at increased risk for macrovascular events as well as for microvascular complications. There is evidence that in patients with coronary artery disease (CAD), about 35 % suffer from manifest T2DM. Early glucose-lowering intervention in subjects with T2DM has been demon...

journal_title：Trials

authors： Tripolt NJ,Aberer F,Riedl R,Hutz B,Url J,Dimsity G,Meinitzer A,Stojakovic T,Hödl R,Brodmann M,Hafner F,Sourij H

更新日期：2016-10-13 00:00:00

abstract：BACKGROUND:The physical and mental health of college students tends to continuously decline around the world. Since they are in a significant transition period which presents opportunities and challenges in health promotion, it is important to improve their health in this period. As a traditional Chinese exercise form ...

journal_title：Trials

authors： Zheng G,Li M,Lan X,Yan X,Lin Q,Chen L,Tao J,Zheng X,Li J,Chen B,Fang Q

更新日期：2013-12-05 00:00:00