Smartphone-based secondary prevention intervention for university students with unhealthy alcohol use identified by screening: study protocol of a parallel group randomized controlled trial.

abstract：BACKGROUND:Emerging evidence has shown that vitamin D and magnesium have anti-inflammatory and anti-depressant effects. Dietary intake of magnesium is associated with reduced body mass index, waist circumference, body fat percentage, as well as inflammatory biomarkers and depressive symptoms. Vitamin D deficiency has b...

journal_title：Trials

authors： Abiri B,Vafa M

更新日期：2020-02-26 00:00:00

abstract：BACKGROUND:Attrition is problematic in trials, and may be exacerbated in longer studies, telehealth trials and participants with depression - three features of The Healthlines Study. Advance notification, including a photograph and using action-oriented email subject lines might increase response rates, but require fur...

journal_title：Trials

authors： Edwards L,Salisbury C,Horspool K,Foster A,Garner K,Montgomery AA

更新日期：2016-02-24 00:00:00

abstract：BACKGROUND:Graves' hyperthyroidism is an autoimmune disease causing hyperfunction of the thyroid gland. The concentration of selenium is high in the thyroid gland and two important groups of enzymes within the thyroid are selenoproteins, that is, they depend on selenium. Selenium may have beneficial effects on autoimmu...

journal_title：Trials

authors： Watt T,Cramon P,Bjorner JB,Bonnema SJ,Feldt-Rasmussen U,Gluud C,Gram J,Hansen JL,Hegedüs L,Knudsen N,Bach-Mortensen P,Nolsøe R,Nygaard B,Pociot F,Skoog M,Winkel P,Rasmussen AK

更新日期：2013-04-30 00:00:00

abstract：BACKGROUND:Acupuncture is a widely serviced complementary medicine. Although acupuncture is suggested for managing postoperative ileus and pain, supporting evidence is weak. The AcuLap trial is designed to provide high-level evidence regarding whether or not electroacupuncture is effective in promoting gastrointestinal...

journal_title：Trials

authors： Kim G

更新日期：2015-10-14 00:00:00

abstract：BACKGROUND:Impairment in social functioning is a key component of personality disorder. Therefore psycho-education and problem solving (PEPS) therapy may benefit people with this disorder. Psycho-education aims to educate, build rapport, and motivate people for problem solving therapy. Problem solving therapy aims to h...

journal_title：Trials

authors： McMurran M,Crawford MJ,Reilly JG,McCrone P,Moran P,Williams H,Adams CE,Duggan C,Delport J,Whitham D,Day F

更新日期：2011-08-24 00:00:00

abstract：BACKGROUND:Obesity represents a major public health problem and is the fifth leading risk factor for mortality. Morbid obesity is associated with chronic systemic inflammation which increases the risk of comorbidities. Bariatric surgery (BS) is considered an effective intervention for obese patients. However, BS is ass...

journal_title：Trials

authors： Delgado André L,Basso-Vanelli RP,Di Thommazo-Luporini L,Angélica Ricci P,Cabiddu R,Pilon Jürgensen S,Ricardo de Oliveira C,Arena R,Borghi-Silva A

更新日期：2018-10-31 00:00:00

abstract：BACKGROUND:Nursing home residents are frequently affected by joint contractures, which impacts their participation and daily activities. A complex intervention, the Participation Enabling Care in Nursing (PECAN), was previously developed and pilot tested to address their needs. Its effectiveness and safety will be eval...

journal_title：Trials

authors： Nguyen N,Thalhammer R,Beutner K,Saal S,Servaty R,Klingshirn H,Icks A,Freyberg K,Vomhof M,Mansmann U,Le L,Müller M,Meyer G

更新日期：2019-05-29 00:00:00

abstract：BACKGROUND/AIMS:Prediabetes and diabetes disproportionately impact Latino youth, yet few diabetes prevention programs have prioritized inclusion of this underrepresented population. This report describes the recruitment process, yields, associated costs, and phenotypic characteristics of Latino youth with obesity and p...

journal_title：Trials

authors： Vander Wyst KB,Olson ML,Hooker E,Soltero EG,Konopken YP,Keller CS,Castro FG,Williams AN,Fernández ADR,Patrick DL,Ayers SL,Hu HH,Peña A,Pimentel J,Knowler WC,Shaibi GQ

更新日期：2020-08-14 00:00:00

abstract：OBJECTIVE:The objective of the Dutch Sildenafil therapy in dismal prognosis early onset fetal growth restriction (STRIDER) randomised clinical trial is to assess the beneficial and harmful effects of sildenafil versus placebo on fetal and neonatal mortality in pregnant women with severe early-onset fetal growth restric...

journal_title：Trials

authors： Pels A,Jakobsen JC,Ganzevoort W,Naaktgeboren CA,Onland W,van Wassenaer-Leemhuis AG,Gluud C

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:Dizziness is one of the most challenging symptoms in medicine. No medication for dizziness in current use has well-established curative or prophylactic value or is suitable for long-term palliative use. Unconventional remedies, such as acupuncture, should be considered and scientifically evaluated. However, ...

journal_title：Trials

authors： Xue Z,Liu CZ,Shi GX,Liu Y,Li ZX,Zhang ZH,Wang LP

更新日期：2013-12-13 00:00:00

abstract：BACKGROUND:People with serious mental illness (SMI) (psychosis, bipolar disorder and major depressive disorder) experience a considerable risk of premature mortality because of cardiovascular disease. Recent research has demonstrated that this population spends almost 13 h per day being sedentary. Sedentary behaviour i...

journal_title：Trials

authors： Williams J,Stubbs B,Gaughran F,Craig T

更新日期：2016-12-12 00:00:00

abstract：BACKGROUND:Transurethral resection of the prostate (TURP) has been the standard operation for benign prostatic obstruction (BPO) for 40 years, with approximately 25,000 procedures performed annually, and has remained largely unchanged. It is generally a successful operation, but has well-documented risks for the patien...

journal_title：Trials

authors： Worthington J,Taylor H,Abrams P,Brookes ST,Cotterill N,Noble SM,Page T,Swami KS,Lane JA,Hashim H

更新日期：2017-04-17 00:00:00

abstract：BACKGROUND:Rural areas of India exhibit high neonatal mortality, and low literacy and numeracy. We assess the effect of a complex package of health interventions on neonatal survival and the effect of out-of-school-hours teaching on children's literacy and numeracy in rural Madhya Pradesh. METHODS/DESIGN:This is a clu...

journal_title：Trials

authors： Agarwal A,Banerji R,Boone P,Elbourne D,Fazzio I,Frost C,Gopal M,Karnati S,Nair R,Reddy H,Reddy P,Sharma D,Shekhawat SS,Shivalli S

更新日期：2020-06-25 00:00:00

abstract：BACKGROUND:Basal cell carcinoma is the most common skin cancer worldwide. Treatment options include both surgical and topical modalities. Although risk of metastasis is low, basal cell carcinoma can be invasive and infiltrate important underlying structures such as bone or cartilage. While many clinical trials examinin...

journal_title：Trials

authors： Schlessinger DI,Iyengar S,Yanes AF,Lazaroff JM,Godinez-Puig V,Chen BR,Kurta AO,Henley JK,Chiren SG,Furlan KC,Schmitt J,Deckert S,Poon E,Sobanko JF,Cartee TV,Alam M,Maher IA

更新日期：2017-10-23 00:00:00

abstract：BACKGROUND:Currently, there still is no treatment that eliminates tinnitus in all patients. Recent studies have shown that Tinnitus Retraining Therapy (TRT) significantly improves quality of life for tinnitus patients. Also, several studies have reported that transcranial Direct Current Stimulation (tDCS) has a positiv...

journal_title：Trials

authors： Rabau S,Van Rompaey V,Van de Heyning P

更新日期：2015-11-10 00:00:00

abstract：BACKGROUND:Maintaining adequate oxygenation during rapid sequence intubation (RSI) is imperative to prevent peri-intubation adverse events that can lead to increased duration of hospital and intensive care unit stay, or a prolonged vegetative state requiring long-term institutionalisation. Despite employing current bes...

journal_title：Trials

authors： Chua MT,Khan FA,Ng WM,Lu Q,Low MJW,Yau YW,Punyadasa A,Kuan WS

更新日期：2019-04-04 00:00:00

abstract：BACKGROUND:Delirium prevalence in the intensive care unit (ICU) is high. Numerous psychotropic agents are used to manage delirium in the ICU with limited data regarding their efficacy or harms. METHODS/DESIGN:This is a randomized controlled trial of 428 patients aged 18 and older suffering from delirium and admitted t...

journal_title：Trials

authors： Campbell NL,Khan BA,Farber M,Campbell T,Perkins AJ,Hui SL,Abernathy G,Buckley J,Sing R,Tricker J,Zawahiri M,Boustani MA

更新日期：2011-06-06 00:00:00

abstract：:Data sharing from clinical trials is one way of promoting fair and transparent conduct of clinical trials. It would maximise the use of data and permit the exploration of additional hypotheses. On the other hand, the quality of secondary analyses cannot always be ascertained, and it may be unfair to investigators who ...

journal_title：Trials

authors： Mbuagbaw L,Foster G,Cheng J,Thabane L

更新日期：2017-02-14 00:00:00

abstract：BACKGROUND:As intensive care mortality is high, end of life is a subject of major concern for intensivists. In this context, relatives are particularly vulnerable and prone to post-ICU syndrome, in the form of high levels of anxiety, depression, post-traumatic stress, and complicated grief. Grieving families suffer fro...

journal_title：Trials

authors： Kentish-Barnes N,Chevret S,Azoulay E

更新日期：2016-02-20 00:00:00

abstract：BACKGROUND:Neurofeedback has been applied effectively in various areas, especially in the treatment of children with attention-deficit/hyperactivity disorder (ADHD). This study protocol is designed to investigate the effect of slow cortical potential (SCP) feedback and a new form of neurofeedback using near-infrared sp...

journal_title：Trials

authors： Mayer K,Wyckoff SN,Fallgatter AJ,Ehlis AC,Strehl U

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:Halitosis is an unpleasant breath odour that can interfere with the professional life, social life and quality of life of people who suffer from it. A modality of treatment that has been increasing in dentistry is antimicrobial photodynamic therapy (aPDT). Bixa orellana, popularly known as "urucum" is a plan...

journal_title：Trials

authors： Gonçalves MLL,da Mota ACC,Deana AM,Guedes GH,Cavalcante LAS,Prates RA,Horliana ACRT,Pavani C,Motta LJ,Bitencourt GB,Fernandes KPS,Salgueiro MDCC,Mesquita-Ferrari RA,da Silva DFT,França CM,Bussadori SK

更新日期：2018-10-29 00:00:00

abstract：:In October 2015 we published the paper 'Measurement of HbA1c in multicentre diabetes trials - should blood samples be tested locally or sent to a central laboratory: an agreement analysis'. Chatterjee and Pradhan have submitted a letter to the editor asking critical questions regarding the methods we used. We offer th...

journal_title：Trials

authors： Arch BN,Blair J,McKay A,Gregory JW,Newland P,Gamble C

更新日期：2017-05-26 00:00:00

abstract：BACKGROUND:Socially disadvantaged men are at a substantially higher risk of developing alcohol-related problems. The frequency of heavy drinking in a single session is high among disadvantaged men. Brief alcohol interventions were developed for, and are usually delivered in, healthcare settings. The group who binge dri...

journal_title：Trials

authors： Crombie IK,Irvine L,Williams B,Sniehotta FF,Petrie D,Evans JM,Emslie C,Jones C,Ricketts IW,Humphris G,Norrie J,Rice P,Slane PW

更新日期：2014-12-19 00:00:00

abstract：BACKGROUND:Nitrogen containing bisphosphonates such as zoledronic acid (ZA) are known to contain certain anti-cancer properties. These have been investigated in the past in various cancers such as breast, prostate and colon. ZA in particular has shown promising results in pre-clinical studies. We propose a multicentre ...

journal_title：Trials

authors： de Fonseka D,Morley A,Stadon L,Keenan E,Walker S,Smith S,Harvey JE,Cox RA,Dangoor A,Comins C,Rogers C,Edey A,Addeo A,Maskell NA

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:The success of a clinical trial is often dependant on whether recruitment targets can be met in the required time frame. Despite an increase in research into the benefits of exercise in people with multiple sclerosis (PwMS), no trial has reported detailed data on effective recruitment strategies for large-sc...

journal_title：Trials

authors： Carter A,Humphreys L,Snowdon N,Sharrack B,Daley A,Petty J,Woodroofe N,Saxton J

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:Around 35-45 % of people in contact with services for a first episode of psychosis are using cannabis. Cannabis use is associated with delays in remission, poorer clinical outcomes, significant increases in the risk of relapse, and lower engagement in work or education. While there is a clear need for effect...

journal_title：Trials

authors： Johnson S,Sheridan Rains L,Marwaha S,Strang J,Craig T,Weaver T,McCrone P,King M,Fowler D,Pilling S,Marston L,Omar RZ,Craig M,Hinton M

更新日期：2016-10-22 00:00:00

abstract：BACKGROUND:Juvenile idiopathic arthritis (JIA)-associated uveitis is a chronic paediatric ocular inflammatory condition that can result in visual impairment. Adalimumab, a tumour necrosis factor (TNF)-alpha inhibitor, effectively controls joint and eye inflammation; however, its long-term use may increase the risk of a...

journal_title：Trials

authors： Acharya NR,Ebert CD,Kelly NK,Porco TC,Ramanan AV,Arnold BF,ADJUST Research Group.

更新日期：2020-10-27 00:00:00

abstract：BACKGROUND:There is a large treatment gap with few community services for people with schizophrenia in low income countries largely due to the shortage of specialist mental healthcare human resources. Community based rehabilitation (CBR), involving lay health workers, has been shown to be feasible, acceptable and more ...

journal_title：Trials

authors： Chatterjee S,Leese M,Koschorke M,McCrone P,Naik S,John S,Dabholkar H,Goldsmith K,Balaji M,Varghese M,Thara R,Patel V,Thornicroft G,COmmunity care for People with Schizophrenia in India (COPSI) group.

更新日期：2011-01-13 00:00:00

abstract：BACKGROUND:Postoperative upper gastrointestinal fistula (PUGIF) is a devastating complication, leading to high mortality (reaching up to 80%), increased length of hospital stay, reduced health-related quality of life and increased health costs. Nutritional support is a key component of therapy in such cases, which is r...

journal_title：Trials

authors： Gronnier C,Chambrier C,Duhamel A,Dervaux B,Collet D,Vaudoyer D,Régimbeau JM,Jougon J,Théréaux J,Lebreton G,Veziant J,Valverde A,Ortega-Deballon P,Pattou F,Mathonnet M,Perinel J,Beyer-Berjot L,Fuks D,Rouanet P,Lefevr

更新日期：2020-06-02 00:00:00

abstract：BACKGROUND:Hypothyroidism is a prevalent endocrine condition. Individuals with this disease are commonly managed through supplementation with synthetic thyroid hormone, with the aim of alleviating symptoms and restoring normal thyroid stimulating hormone levels. Generally this management strategy is effective and well ...

journal_title：Trials

authors： Brown BT,Bonello R,Pollard H,Graham P

更新日期：2010-11-15 00:00:00