Predicting ulcer-free survival using the discriminative value of screening test locations.

abstract：AIMS/HYPOTHESIS:In type 2 diabetes mellitus (T2DM), the abnormal protein and lipid composition of diabetic high-density lipoprotein (HDL) could impair its anti-inflammatory functions. Whether nonenzymatic glycation directly impaired the anti-inflammatory effects of HDL in innate immunity remained unclear. METHODS:Huma...

journal_title：Diabetes/metabolism research and reviews

authors： Liu D,Ji L,Zhang D,Tong X,Pan B,Liu P,Zhang Y,Huang Y,Su J,Willard B,Zheng L

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Intensive insulin therapy is the gold standard by which Type 1 diabetes is treated. In addition to this therapy, administration of nicotinamide (NA) can be beneficial. This concept is reinforced by the results of a recent meta-analysis of the use of NA in patients with recent-onset Type 1 diabetes. METHODS:...

journal_title：Diabetes/metabolism research and reviews

authors： Visalli N,Cavallo MG,Signore A,Baroni MG,Buzzetti R,Fioriti E,Mesturino C,Fiori R,Lucentini L,Matteoli MC,Crinò A,Corbi S,Spera S,Teodonio C,Paci F,Amoretti R,Pisano L,Suraci C,Multari G,Sulli N,Cervoni M,De Mat

更新日期：1999-05-01 00:00:00

abstract：:Various different systems have been proposed to classify diabetic foot ulcers, but none has gained widespread acceptance. The International Working Group of the Diabetic Foot (IWGDF) developed a classification system for research purposes, which is described in this report. In this PEDIS system, all foot ulcers should...

journal_title：Diabetes/metabolism research and reviews

authors： Schaper NC

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Recently, a genome-wide association study identified a strong association between the fat mass- and obesity-associated rs9939609 single nucleotide polymorphism (SNP) and the risk of obesity in European population. However, the results in Chinese population were reported to be contradictory. Therefore, our ai...

journal_title：Diabetes/metabolism research and reviews

authors： Li X,Song F,Jiang H,Zhang M,Lin J,Bao W,Yao P,Yang X,Hao L,Liu L

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Sodium-glucose cotransporter 2 (SGLT2) inhibitors could potentially alter calcium and phosphate homeostasis and may increase the risk of bone fracture. METHODS:The current meta-analysis was conducted to investigate the fracture risk among patients with type 2 diabetes mellitus treated with SGLT2 inhibitors....

journal_title：Diabetes/metabolism research and reviews

authors： Ruanpeng D,Ungprasert P,Sangtian J,Harindhanavudhi T

更新日期：2017-09-01 00:00:00

abstract：:Sodium-glucose cotransporter (SGLT) inhibitors added to insulin therapy have been proposed as treatment strategy for type 1 diabetes (T1D). We thus conducted a meta-analysis of randomized controlled trials (RCTs) to assess the efficacy and adverse effects of this combination in T1D. We searched the PubMed, EMBASE, and...

journal_title：Diabetes/metabolism research and reviews

authors： Lu J,Tang L,Meng H,Zhao J,Liang Y

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Patients with impaired 50-g oral glucose challenge test (OGCT) have not been investigated for fetal anterior abdominal wall thickness until now. We aimed to investigate patients with impaired 50-g OGCT, but not gestational diabetes and match them with healthy uneventful pregnant participants for anterior abd...

journal_title：Diabetes/metabolism research and reviews

authors： Aksoy H,Aksoy U,Açmaz G,Tutuş S

更新日期：2014-10-01 00:00:00

abstract：:Studies on skeletal involvement in patients with diabetes mellitus have generated conflicting results, largely because of the pathogenetic complexity of the condition. Several mechanisms may contribute to skeletal damage, including the increased urinary excretion coupled with the lower intestinal absorption of calcium...

journal_title：Diabetes/metabolism research and reviews

authors： Carnevale V,Romagnoli E,D'Erasmo E

更新日期：2004-05-01 00:00:00

abstract：:In several large recent observational studies, peripheral arterial disease (PAD) was present in up to 50% of the patients with a diabetic foot ulcer and was an independent risk factor for amputation. The International Working Group on the Diabetic Foot therefore established a multidisciplinary working group to evaluat...

journal_title：Diabetes/metabolism research and reviews

authors： Hinchliffe RJ,Andros G,Apelqvist J,Bakker K,Friederichs S,Lammer J,Lepantalo M,Mills JL,Reekers J,Shearman CP,Valk G,Zierler RE,Schaper NC

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The aim of the study is to assess the relationship between the shape of plasma glucose concentration during the OGTT and future risk for T2DM. METHODS:2445 non-diabetic subjects from the Botnia study received an OGTT at baseline and after 7-8 years of follow-up. RESULTS:NGT and IFG subjects who returned th...

journal_title：Diabetes/metabolism research and reviews

authors： Abdul-Ghani MA,Lyssenko V,Tuomi T,Defronzo RA,Groop L

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Adiponectin acts as an insulin sensitizer in rodent models. The direct effect of adiponectin in intact type 2 diabetic muscle is unknown. We examined whether adiponectin stimulates glucose transport in isolated skeletal muscle strips from type 2 diabetic men. METHODS:We obtained open muscle biopsies from 12...

journal_title：Diabetes/metabolism research and reviews

authors： Kuoppamaa H,Skrobuk P,Sihvo M,Hiukka A,Chibalin AV,Zierath JR,Koistinen HA

更新日期：2008-10-01 00:00:00

abstract：:Small fibres constitute 70-90% of peripheral nerve fibres and regulate several key functions such as tissue blood flow, temperature and pain perception as well as sweating, all of which are highly relevant to the clinical presentation and adverse outcomes associated with foot ulcerations in patients with diabetes. Rec...

journal_title：Diabetes/metabolism research and reviews

authors： Malik RA,Veves A,Tesfaye S,Smith G,Cameron N,Zochodne D,Lauria G,Toronto Consensus Panel on Diabetic Neuropathy.

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:High birth weight has been related to an increased risk of type 1 diabetes (T1D), while suboptimal birth weight (both high and low) has been related to obesity, insulin resistance and type 2 diabetes. Insulin resistance, as a consequence of poor metabolic control, has been described in T1D patients. The aims...

journal_title：Diabetes/metabolism research and reviews

authors： Benevento D,Bizzarri C,Patera IP,Ravà L,Schiaffini R,Ciampalini P,Cianfarani S,Cappa M

更新日期：2013-01-01 00:00:00

abstract：:Around one of three diabetic patients is affected by distal symmetric polyneuropathy (DSP) which represents a major health problem, as it may present with partly excruciating neuropathic pain and is responsible for substantial morbidity and increased mortality. Treatment is based on four cornerstones: (1) multifactori...

journal_title：Diabetes/metabolism research and reviews

authors： Ziegler D

更新日期：2008-05-01 00:00:00

abstract：:The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and expert consultants in the field, this update is based on a systematic review of ...

journal_title：Diabetes/metabolism research and reviews

authors： Rayman G,Vas P,Dhatariya K,Driver V,Hartemann A,Londahl M,Piaggesi A,Apelqvist J,Attinger C,Game F,International Working Group on the Diabetic Foot (IWGDF).

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:We conducted this research in order to evaluate the prevalence of glutamic acid decarboxylase antibodies (GADA) in Korean women with gestational diabetes mellitus (GDM), to identify the clinical characteristics of these women, and to gauge the prevalence of diabetes among them after childbirth. METHODS:We s...

journal_title：Diabetes/metabolism research and reviews

authors： Yu SH,Park S,Kim HS,Park SY,Yim CH,Han KO,Yoon HK,Jang HC,Chung HY,Kim SH

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:T1DM is a T-cell-mediated autoimmune disease targeting insulin-producing beta-cells. Multiple factors may contribute to the development of T1DM. Among these, the metabolic state of beta-cells and pro-inflammatory cytokines, produced by infiltrating immune cells, have been implicated in the precipitation of T...

journal_title：Diabetes/metabolism research and reviews

authors： Osterbye T,Funda DP,Fundová P,Månsson JE,Tlaskalová-Hogenová H,Buschard K

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Women with obesity and type 2 diabetes (T2D) are at greater risk of dying from breast cancer than women without these conditions. Obesity and T2D are associated with insulin resistance and endogenous hyperinsulinemia and are more common in Black women. There is increasing disparity in breast cancer mortality...

journal_title：Diabetes/metabolism research and reviews

authors： Gallagher EJ,LeRoith D,Franco R,Antoniou IM,Nayak A,Livaudais-Toman J,Bickell NA

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:This article aims to describe the implementation and initial results of an audit-feedback quality improvement initiative in Belgian diabetic foot clinics. METHODS:Using self-developed software and questionnaires, diabetic foot clinics collected data in 2005, 2008 and 2011, covering characteristics, history ...

journal_title：Diabetes/metabolism research and reviews

authors： Doggen K,Van Acker K,Beele H,Dumont I,Félix P,Lauwers P,Lavens A,Matricali GA,Randon C,Weber E,Van Casteren V,Nobels F,Initiative for Quality Improvement and Epidemiology in Diabetic Foot Clinics (IQED-Foot) Study Group.

更新日期：2014-07-01 00:00:00

abstract：:A few studies have investigated the relationship between type 1 diabetes mellitus (T1DM) and bone mineral density (BMD) values. This meta-analysis was performed to explore differences between T1DM and healthy individuals in BMD values measured at five bone sites.We searched the database of PubMed for cross-sectional s...

journal_title：Diabetes/metabolism research and reviews

authors： Pan H,Wu N,Yang T,He W

更新日期：2014-10-01 00:00:00

abstract：AIMS:Diabetic neuropathy (DN) is a "Cinderella" complication, particularly in the Middle East. A high prevalence of undiagnosed DN and those at risk of diabetic foot ulceration (DFU) is a major concern. We have determined the prevalence of DN and its risk factors, DFU, and those at risk of DFU in patients with type 2 d...

journal_title：Diabetes/metabolism research and reviews

authors： Ponirakis G,Elhadd T,Chinnaiyan S,Dabbous Z,Siddiqui M,Al-Muhannadi H,Petropoulos IN,Khan A,Ashawesh KAE,Dukhan KMO,Mahfoud ZR,Murgatroyd C,Slevin M,Malik RA

更新日期：2020-05-01 00:00:00

abstract：:There are a number of medical conditions such as growth failure in children, pregnancy, lipid abnormalities, and early complications that are improved by the meticulous glycemic control that can be achieved with insulin pump therapy (CSII). By using an insulin pump, many patients with severe hypoglycemia, the dawn phe...

journal_title：Diabetes/metabolism research and reviews

authors： Kaufman FR,Halvorson M,Miller D,Mackenzie M,Fisher LK,Pitukcheewanont P

更新日期：1999-09-01 00:00:00

abstract：:Four kinds of subcutaneous continuous glucose monitoring (CGM) machines have been currently introduced in clinical practice. These machines exhibit real-time glucose on the monitor every 5 minutes and have alarms to indicate hypoglycaemia and hyperglycaemia. However, thus far, there is no clear consensus about the cli...

journal_title：Diabetes/metabolism research and reviews

authors： Kim HS,Shin JA,Chang JS,Cho JH,Son HY,Yoon KH

更新日期：2012-12-01 00:00:00

abstract：:The increasing global prevalence of type 2 diabetes mellitus (T2DM) requires the implementation of preventive strategies to halt this trend, tailored to the specific needs of individual regions. Risk factors for T2DM are among the main targets for improving health outcomes and curbing the development of diabetes; exce...

journal_title：Diabetes/metabolism research and reviews

authors： Palermo A,Maggi D,Maurizi AR,Pozzilli P,Buzzetti R

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Adenosine triphosphate (ATP) is a critical determinant of beta-cell insulin secretion in response to glucose. BHE/cdb rats have a mutation in ATP synthase that limits ATP production, yet develop mild diabetes only with ageing. We investigated the cellular basis for reduced insulin secretion and compensatory ...

journal_title：Diabetes/metabolism research and reviews

authors： Saleh MC,Fatehi-Hassanabad Z,Wang R,Nino-Fong R,Wadowska DW,Wright GM,Harper ME,Chan CB

更新日期：2008-07-01 00:00:00

abstract：:Patients with diabetes may undergo an approximately 24-h fast for a voluntary religious observance or in preparation for a medical procedure. Commonly, patients will manage their diabetes before and during such fasting without guidelines from their doctors, often because they did not ask for advice. The physician shou...

journal_title：Diabetes/metabolism research and reviews

authors： Grajower MM

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Lispro Mix 25% insulin lispro/75% insulin lispro protamine (LM25) and Lispro Mix 50% insulin lispro/50% insulin lispro protamine (LM50) were compared as starter insulins in East Asian patients with type 2 diabetes. METHODS:Phase 4, open-label, randomized trial conducted in China, Japan, Korea, and Turkey. S...

journal_title：Diabetes/metabolism research and reviews

authors： Watada H,Su Q,Li PF,Iwamoto N,Qian L,Yang WY

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The genetic basis of the autoimmune disease type 1 diabetes (T1D) has now been largely determined, so now we can compare these findings with emerging genetic knowledge of disorders and phenotypes that have been negatively or positively associated with T1D historically. Here, we assessed the role in T1D of va...

journal_title：Diabetes/metabolism research and reviews

authors： Saleh NM,Raj SM,Smyth DJ,Wallace C,Howson JM,Bell L,Walker NM,Stevens HE,Todd JA

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing in developing countries, but its causes are not known. We aimed to ascertain the prevalence and determinants of NAFLD in a new largely unmedicated population-based cohort from the rapidly gentrifying region of Pinggu, China. METHODS:We ran...

journal_title：Diabetes/metabolism research and reviews

authors： Zhou X,Li Y,Zhang X,Guan YY,Puentes Y,Zhang F,Speliotes EK,Ji L

更新日期：2019-07-01 00:00:00

abstract：:Every year, over 1 million people with diabetes lose a leg due to diabetic foot disease. Most amputations are preceded by a foot ulcer. Causes for the development of foot ulcers are generally multifactorial and may include neuropathy, peripheral vasculopathy, abnormal foot mechanics and infection. Multidisciplinary ap...

journal_title：Diabetes/metabolism research and reviews

authors： Cahn A,Elishuv O,Olshtain-Pops K

更新日期：2014-07-01 00:00:00