Diabetic foot ulcer classification system for research purposes: a progress report on criteria for including patients in research studies.

abstract：BACKGROUND:Levels of high-sensitivity C-reactive protein (hs-CRP) and adiponectin, reflecting chronic inflammation, are associated with cardiovascular disease in type 2 diabetes. The long-term effects of multifactorial therapy in type 2 diabetes patients on CRP and adiponectin are unknown. METHODS:The ADDITION-NL stud...

journal_title：Diabetes/metabolism research and reviews

authors： den Ouden H,Berends J,Stellato RK,Beulens JW,Rutten GE

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:HLA region is the major locus (IDDM1) of type 1 diabetes (T1D) susceptibility. It explains approximately 50% of the genetic background of T1D, indicating additional genetic determinants. Genome scans and candidate gene studies have generated several chromosomal candidate regions that may have a role in T1D d...

journal_title：Diabetes/metabolism research and reviews

authors： Laine AP,Nejentsev S,Veijola R,Korpinen E,Sjöroos M,Simell O,Knip M,Akerblom HK,Ilonen J

更新日期：2004-03-01 00:00:00

abstract：:Abstinence from food and liquid during daylight hours is observed by Muslim individuals during the month of Ramadan. Even though the Koran exempts the sick from fasting, many people with diabetes still fast during this religious period. It is essential for patients, family and healthcare professionals to be aware of t...

journal_title：Diabetes/metabolism research and reviews

authors： Hui E,Devendra D

更新日期：2010-11-01 00:00:00

abstract：:This review addresses the roles of Rho/Rho-kinase (ROCK) pathway in the pathogenesis of diabetes complications. Diabetes can cause many serious complications and can result in physical disability or even increased mortality. However, there are not many effective ways to treat these complications. The small guanosine-5...

journal_title：Diabetes/metabolism research and reviews

authors： Zhou H,Li Y

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between ankle-branchial index (ABI) and cardiovascular disease in type 2 diabetes patients. METHODS:A total of 634 inpatients with type 2 diabetes were recruited in this cross-sectional study. All patients were measured with ABI and computed tomography angiography (CTA) scan f...

journal_title：Diabetes/metabolism research and reviews

authors： Xu L,He R,Hua X,Zhao J,Zhao J,Zeng H,Li L,Liu F,Jia W

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Although obesity has been associated with a higher risk for premature death, the sex and ethnic-origin specific body mass index (BMI) levels that are associated with increased mortality are controversial. We investigated the 40-year cumulative all-cause mortality, in relation to the BMI in adult life, among ...

journal_title：Diabetes/metabolism research and reviews

authors： Dankner R,Shanik M,Roth J,Luski A,Lubin F,Chetrit A

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The prevalence of type 2 diabetes in China is increasing rapidly. Appropriate management of glycemia, blood pressure and dyslipidemia in this population is a major public health concern. OBJECTIVE:The aim of this study was to assess metabolic control including glycated hemoglobin A1c (HbA1c ), blood pressur...

journal_title：Diabetes/metabolism research and reviews

authors： Liu L,Lou Q,Guo X,Yuan L,Shen L,Sun Z,Zhao F,Dai X,Huang J,Yang H,Mordes JP,Chinese Diabetes Education Status Survey Study Group.

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Advanced glycosylation end product (AGE) formation is a major mechanism for the development of complications in diabetes, and the possible roles of insulin-like growth factor 1 (IGF-1) and IGF binding protein 3 (IGFBP-3) are not clearly established. METHODS:We examined the associations of AGEs, free IGF-I a...

journal_title：Diabetes/metabolism research and reviews

authors： Garay-Sevilla ME,Nava LE,Malacara JM,Wróbel K,Wróbel K,Pérez U

更新日期：2000-03-01 00:00:00

abstract：:Since the publication of the United Kingdom Prospective Diabetes Study (UKPDS), the progressive nature of type 2 (DM2) diabetes has been identified as the main cause of failure to maintain a long term glycemic control.[1] The need to adjust treatment as the disease progressed was recognized and algorithms for treatmen...

journal_title：Diabetes/metabolism research and reviews

authors： Eliaschewitz FG,Tambascia MA

更新日期：2012-12-05 00:00:00

abstract：BACKGROUND:The possible effect of random intrasite placement on the outcome of the Semmes-Weinstein monofilament (SWF) test is not known. We sought to determine the significance of this variable in the diagnosis of loss of protective sensation (LOPS) in patients with diabetes. METHODS:Forty-five patients with diabetes...

journal_title：Diabetes/metabolism research and reviews

authors： Slater RA,Koren S,Ramot Y,Buchs A,Rapoport MJ

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The aetiology of painful diabetic neuropathy is unclear. We have evaluated vitamin D levels in diabetic patients with and without painful neuropathy. METHODS:Forty-three patients with type 1 diabetes and painless (DPN) (n = 20) or painful (PDN) (n = 23) neuropathy and 14 non-diabetic healthy control subject...

journal_title：Diabetes/metabolism research and reviews

authors： Alam U,Petropoulos IN,Ponirakis G,Ferdousi M,Asghar O,Jeziorska M,Marshall A,Boulton AJM,Efron N,Malik RA

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Despite the correlation between the use of protease inhibitors (PI) and adverse metabolic glycemic events, no prospective study has examined these parameters in pregnant women who use these drugs. METHODS:A prospective study was conducted on 57 pregnant women to investigate the effect of antiretroviral drug...

journal_title：Diabetes/metabolism research and reviews

authors： El Beitune P,Duarte G,Foss MC,Montenegro RM Jr,Spara P,Quintana SM,Figueiró-Filho EA,da Costa AG,Filho FM

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:Atherosclerosis is associated with insulin resistance (IR) and dyslipidaemia. Impaired glucose tolerance (IGT) is characterised by IR and is associated with a higher risk of atherosclerosis. The objective of the present study was to test whether early atherosclerosis indicated by intimal medial thickness (IMT...

journal_title：Diabetes/metabolism research and reviews

authors： Snehalatha C,Vijay V,Suresh Mohan R,Satyavani K,Sivasankari S,Megha T,Radhika S,Ramachandran A

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Hybrid closed-loop (HCL) therapy is rarely studied in pregnancy. We present three cases of women with type 1 diabetes who used the Medtronic 670G HCL system for most or all of gestation. METHODS:The Medtronic 670G system has a manual mode (no automated insulin delivery) and an auto mode (AM, HCL therapy). W...

journal_title：Diabetes/metabolism research and reviews

authors： Polsky S,Akturk HK

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:T1DM is a T-cell-mediated autoimmune disease targeting insulin-producing beta-cells. Multiple factors may contribute to the development of T1DM. Among these, the metabolic state of beta-cells and pro-inflammatory cytokines, produced by infiltrating immune cells, have been implicated in the precipitation of T...

journal_title：Diabetes/metabolism research and reviews

authors： Osterbye T,Funda DP,Fundová P,Månsson JE,Tlaskalová-Hogenová H,Buschard K

更新日期：2010-11-01 00:00:00

abstract：:In the last few years, there has been increasing focus on the impact of interventions on cardiovascular outcomes in patients with type 2 diabetes. Insulin resistance and hyperglycaemia often co-exist with a cluster of risk factors for coronary artery disease, but the underlying mechanisms leading to the development of...

journal_title：Diabetes/metabolism research and reviews

authors： Ceriello A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:We conducted a meta-analysis to investigate the association of circulating tumor necrosis factor-1 (TNFR-1) and TNFR-2 with diabetic kidney disease (DKD) progression, which is the first-ever quantitative analysis of these associations thus far. Whether TNFRs were better than albumin-creatinine ratio (ACR) in...

journal_title：Diabetes/metabolism research and reviews

authors： Ye X,Luo T,Wang K,Wang Y,Yang S,Li Q,Hu J

更新日期：2019-11-01 00:00:00

abstract：AIMS:Insulin-like growth factor 1 receptor (IGF1R) is involved in cell growth and glucose homeostasis. In the current study, the IGF1R locus was analysed as a candidate gene for type 2 diabetes (T2D) in American Indians. MATERIALS AND METHODS:Whole genome sequence data from 335 American Indians identified 3 novel miss...

journal_title：Diabetes/metabolism research and reviews

authors： Muller YL,Skelton G,Piaggi P,Chen P,Nair A,Kobes S,Hsueh WC,Knowler WC,Hanson RL,Baier LJ,Bogardus C

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Cyclosporin A (CyA) may induce acute nephrotoxicity. The question has been raised of the possible long-term unfavorable course of CyA-induced lesions. Advantage was taken of a large cohort of diabetic patients treated for several months using moderate CyA dosage to evaluate the long-term evolution of renal f...

journal_title：Diabetes/metabolism research and reviews

authors： Assan R,Blanchet F,Feutren G,Timsit J,Larger E,Boitard C,Amiel C,Bach JF

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Mutating the insulin B:9-23 peptide prevents diabetes in NOD mice. Thus, the trimolecular complex of I-Ag7-insulin B:9-23 peptide-TCR may be essential for the development of spontaneous diabetes. Pathogenic T cells recognize the B:9-23 peptide presented by I-Ag7 in what is termed register 3, with the B22 bas...

journal_title：Diabetes/metabolism research and reviews

authors： Zhang L,Stadinski BD,Michels A,Kappler JW,Eisenbarth GS

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The incidence of type 1 diabetes mellitus (T1DM) has increased in recent decades, as has the incidence of preterm births (<37 weeks). We aimed to evaluate and compare the prevalence of prematurity and early prematurity (<34 weeks) and birth season variability among T1DM and non-T1DM children. METHODS:A nati...

journal_title：Diabetes/metabolism research and reviews

authors： Adar A,Shalitin S,Eyal O,Loewenthal N,Pinhas-Hamiel O,Levy M,Dally-Gottfried O,Landau Z,Zung A,Levy-Khademi F,Zangen D,Tenenbaum-Rakover Y,Rachmiel M

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) can lead to cirrhosis and hepatocellular carcinoma and is strongly associated with obesity and insulin resistance. The aim of this study was to assess if plasma markers associated with NAFLD are increased in people with concomitant diabetes compared with those withou...

journal_title：Diabetes/metabolism research and reviews

authors： Sharma S,Barrett F,Adamson J,Todd A,Megson IL,Zentler-Munro PL,MacRury SM

更新日期：2012-05-01 00:00:00

abstract：:The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and expert consultants in the field, this update is based on a systematic review of ...

journal_title：Diabetes/metabolism research and reviews

authors： Rayman G,Vas P,Dhatariya K,Driver V,Hartemann A,Londahl M,Piaggesi A,Apelqvist J,Attinger C,Game F,International Working Group on the Diabetic Foot (IWGDF).

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Increased production of reactive oxygen species (ROS) in mitochondria has been proposed as the pathogenic mechanism for chronic complications of diabetes. Mitochondrial DNA (mtDNA) is more vulnerable to reactive oxygen species. However, there are few data on the mitochondrial DNA damage in diabetes and these...

journal_title：Diabetes/metabolism research and reviews

authors： Savu O,Sunkari VG,Botusan IR,Grünler J,Nikoshkov A,Catrina SB

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The cardiovascular effects of sulfonylureas (SU) in diabetic patients are controversial and it has been suggested that diabetic patients with acute myocardial infarction while on SU were at increased risk. OBJECTIVES:To assess the in-hospital outcome of patients with acute myocardial infarction according to...

journal_title：Diabetes/metabolism research and reviews

authors： Danchin N,Charpentier G,Ledru F,Vaur L,Guéret P,Hanania G,Blanchard D,Lablanche JM,Genès N,Cambou JP

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The proposed 2015 US Preventive Services Task Force guidelines recommend diabetes screening for individuals ≥45 years or demonstrating other risk factors for dysglycemia. Still, many patients with dysglycemia remain undiagnosed, and opportunities for early intervention are lost. METHODS:To test novel approa...

journal_title：Diabetes/metabolism research and reviews

authors： Silverman RA,Schleicher MG,Valente CJ,Kim M,Romanenko Y,Schulman RC,Tiberio A,Greenblatt B,Rentala M,Salvador-Kelly AV,Kwon NS,Jornsay DL

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Visceral adiposity index (VAI) is a novel marker of visceral adipose tissue accumulation and dysfunction. The study aim was to explore the association of VAI with the 10-year type 2 diabetes mellitus (T2DM) incidence in apparently healthy individuals and compare its T2DM predictive ability against common ant...

journal_title：Diabetes/metabolism research and reviews

authors： Koloverou E,Panagiotakos DB,Kyrou I,Stefanadis C,Chrysohoou C,Georgousopoulou EN,Skoumas I,Tousoulis D,Pitsavos C,ATTICA Study group.

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes mellitus (DM) has been shown to alter the properties of bone and impair fracture healing in both humans and animals. The objective of this study was to examine changes in the histomorphometrical, histological and mechanical parameters of bone and remodeling during fracture healing, depending ...

journal_title：Diabetes/metabolism research and reviews

authors： Follak N,Klöting I,Merk H

更新日期：2005-05-01 00:00:00

abstract：:Education is essential in insulin pump therapy, but literature in the field is limited. We systematically reviewed insulin pump education programmes and their effects in two situations as follows: (1) basic education at the start of insulin pump therapy, providing the study design enabled us to separate the effects of...

journal_title：Diabetes/metabolism research and reviews

authors： Rytter K,Schmidt S,Rasmussen LN,Pedersen-Bjergaard U,Nørgaard K

更新日期：2020-10-03 00:00:00

abstract：BACKGROUND:Leptin's hematopoietic or proinflammatory role has been experimentally reported. We investigated whether serum leptin concentrations are associated with white blood cell (WBC) counts in humans. METHODS:Serum leptin concentrations of Japanese civil servants aged 40 to 59 years (1082 men and 200 women) were a...

journal_title：Diabetes/metabolism research and reviews

authors： Mabuchi T,Yatsuya H,Tamakoshi K,Otsuka R,Nagasawa N,Zhang H,Murata C,Wada K,Ishikawa M,Hori Y,Kondo T,Hashimoto S,Toyoshima H

更新日期：2005-09-01 00:00:00