The effect of impaired 50-gram oral glucose challenge test on fetal abdominal wall thickness.

Abstract:

BACKGROUND:Patients with impaired 50-g oral glucose challenge test (OGCT) have not been investigated for fetal anterior abdominal wall thickness until now. We aimed to investigate patients with impaired 50-g OGCT, but not gestational diabetes and match them with healthy uneventful pregnant participants for anterior abdominal wall thickness, estimated fetal weight, fetal gender, biparietal diameter, femur length and abdominal circumference. METHODS:A total of 99 pregnant women between 26 and 28 weeks of gestation were enrolled in the study. These patients were divided into two groups according to their 50-g OGCT results. Fifty-one pregnant women with uncomplicated healthy singleton pregnancies constituted our control group, and 48 singleton pregnant women with impaired 50-g OGCT but normal 100-g oral glucose tolerance test constituted our study group. RESULTS:We detected statistically significant high body mass index in impaired 50-g glucose test group. Biparietal diameter, femur length, abdominal circumference and estimated fetal weight values were not significantly different between groups; however, anterior abdominal wall thickness value was significantly width in impaired 50-g glucose test group. Moreover, there were no statistically significant differences between two groups for gender of fetuses. CONCLUSION:Impaired 50-g glucose test in pregnancy is related not only to increased maternal body mass index but also to fetal fat distribution. Although fetal abdominal circumference measurement and estimated fetal weight were not different between study and control group, increased anterior abdominal wall thickness can be detected in impaired 50-g OGCT group.

journal_name

Diabetes Metab Res Rev

authors

Aksoy H,Aksoy U,Açmaz G,Tutuş S

doi

10.1002/dmrr.2511

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

570-4

issue

7

eissn

1520-7552

issn

1520-7560

journal_volume

30

pub_type

杂志文章
  • Association of TCF7L2 SNPs with age at onset of type 2 diabetes and proinsulin/insulin ratio but not with glucagon-like peptide 1.

    abstract:BACKGROUND:Variants in TCF7L2 have been associated with the age at onset of type 2 diabetes in Mexican Americans. However, there is a lack of data on this relationship in Caucasians. Furthermore, risk alleles in TCF7L2 have been suggested to account for decreased conversion of proinsulin to insulin and decreased expres...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.1194

    authors: Silbernagel G,Renner W,Grammer TB,Hügl SR,Bertram J,Kleber ME,Hoffmann MM,Winkelmann BR,März W,Boehm BO

    更新日期:2011-07-01 00:00:00

  • Mitochondrial dysfunction as a central event for mechanisms underlying insulin resistance: the roles of long chain fatty acids.

    abstract::Insulin resistance is characterized by hyperglycaemia, dyslipidaemia and oxidative stress prior to the development of type 2 diabetes mellitus. To date, a number of mechanisms have been proposed to link these syndromes together, but it remains unclear what the unifying condition that triggered these events in the prog...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,评审

    doi:10.1002/dmrr.2601

    authors: Hafizi Abu Bakar M,Kian Kai C,Wan Hassan WN,Sarmidi MR,Yaakob H,Zaman Huri H

    更新日期:2015-07-01 00:00:00

  • Risk factors in V-shaped risk associations with all-cause mortality in type 2 diabetes-The Hong Kong Diabetes Registry.

    abstract:BACKGROUND:Body mass index (BMI) is associated with death in a V-shaped manner in general populations but it is unknown whether BMI or other risk factors also exhibit V-shaped relationships with death in type 2 diabetic patients. METHODS:A prospective cohort of 7534 Chinese, type 2 diabetic patients enrolled since 199...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.792

    authors: So WY,Yang X,Ma RC,Kong AP,Lam CW,Ho CS,Cockram CS,Ko GT,Chow CC,Wong V,Tong PC,Chan JC

    更新日期:2008-03-01 00:00:00

  • Comparing glucose and hemoglobin A1c diagnostic tests among a high metabolic risk Hispanic population.

    abstract:BACKGROUND:Compare glycated hemoglobin (HbA1c ) diagnostic tests for prediabetes and diabetes with plasma glucose criteria and compare the metabolic profiles of people classified by HbA1c versus by glucose levels. METHODS:Participants were recruited for the San Juan Overweight Adults Longitudinal Study. The participan...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2874

    authors: Vega-Vázquez MA,Ramírez-Vick M,Muñoz-Torres FJ,González-Rodríguez LA,Joshipura K

    更新日期:2017-05-01 00:00:00

  • Diabetes and microvascular pathophysiology: role of epidermal growth factor receptor tyrosine kinase.

    abstract::Type 2 diabetes is responsible for the increased prevalence of ischaemic heart disease, generally related to coronary artery disease, which is associated with increased morbidity and death in diabetic patients. Epidermal growth factor receptor (EGFR) tyrosine kinase, one of the many factors involved in cell growth and...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,评审

    doi:10.1002/dmrr.1050

    authors: Matrougui K

    更新日期:2010-01-01 00:00:00

  • MicroRNA-296-5p promotes healing of diabetic wound by targeting sodium-glucose transporter 2 (SGLT2).

    abstract:BACKGROUND:Diabetic wounds are refractory and very difficult to heal. We aimed to use miRNA to identify novel and specific molecular markers for diabetes mellitus (DM) diagnosis and treatment. METHODS:The expression level of miR-296-5p was determined in tissue samples of 12 DM patients. The effect of miR-296-5p on pro...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.3104

    authors: Liu X,Wang Y,Zhang X,Zhang X,Guo J,Zhou J,Chai Y,Ma ZL

    更新日期:2019-02-01 00:00:00

  • Widening awareness of hyperglycemia unawareness.

    abstract::Hyperglycemia unawareness is the term suggested to me (M. Muggeo, personal communication, 1997) to encompass very broadly all of the stages in diabetes mellitus from the onset of any degree of hyperglycemia until the diagnosis is actually made. Diabetes and its handmaiden, obesity, are growing in epidemic proportions ...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 评论,社论

    doi:10.1002/1520-7560(200007/08)16:4<228::aid-dmrr125>

    authors: Roth J

    更新日期:2000-07-01 00:00:00

  • Skeletal involvement in patients with diabetes mellitus.

    abstract::Studies on skeletal involvement in patients with diabetes mellitus have generated conflicting results, largely because of the pathogenetic complexity of the condition. Several mechanisms may contribute to skeletal damage, including the increased urinary excretion coupled with the lower intestinal absorption of calcium...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,评审

    doi:10.1002/dmrr.449

    authors: Carnevale V,Romagnoli E,D'Erasmo E

    更新日期:2004-05-01 00:00:00

  • Management status and its predictive factors in patients with type 2 diabetes in China: A Nationwide Multicenter Study: A Nationwide Multicenter Study.

    abstract:BACKGROUND:The prevalence of type 2 diabetes in China is increasing rapidly. Appropriate management of glycemia, blood pressure and dyslipidemia in this population is a major public health concern. OBJECTIVE:The aim of this study was to assess metabolic control including glycated hemoglobin A1c (HbA1c ), blood pressur...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,多中心研究

    doi:10.1002/dmrr.2757

    authors: Liu L,Lou Q,Guo X,Yuan L,Shen L,Sun Z,Zhao F,Dai X,Huang J,Yang H,Mordes JP,Chinese Diabetes Education Status Survey Study Group.

    更新日期:2015-11-01 00:00:00

  • Serum ferritin and glucose homeostasis: change in the association by glycaemic state.

    abstract:BACKGROUND:Data on the association between body iron and glucose homeostasis by the three glycaemic states are scarce. Thus, we investigated the association between body iron as assessed by a serum ferritin concentration and glucose homeostasis using homeostasis model assessment (HOMA) of insulin resistance (HOMA-IR) a...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2628

    authors: Aregbesola A,Virtanen JK,Voutilainen S,Mursu J,Lagundoye A,Kauhanen J,Tuomainen TP

    更新日期:2015-07-01 00:00:00

  • Basal insulin analogues in diabetic pregnancy: a literature review and baseline results of a randomised, controlled trial in type 1 diabetes.

    abstract::As basal insulin analogues are being used off-label, there is a need to evaluate their safety (maternal hypoglycaemia and fetal and perinatal outcomes) and efficacy [haemoglobin A1c(HbA1c), fasting plasma glucose, and maternal weight gain]. The aim of this review is to provide an overview of the current literature con...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,多中心研究,随机对照试验,评审

    doi:10.1002/dmrr.1213

    authors: Mathiesen ER,Damm P,Jovanovic L,McCance DR,Thyregod C,Jensen AB,Hod M

    更新日期:2011-09-01 00:00:00

  • Advanced complicated diabetes mellitus is associated with a reduced risk of thoracic and abdominal aortic aneurysm rupture: a population-based cohort study.

    abstract:BACKGROUND:Studies have associated diabetes mellitus (DM) with the reduced risk of abdominal aortic aneurysm and thoracic aortic aneurysm and dissection. We used the national insurance data of Taiwan to examine these correlations for an Asian population. The association was also evaluated by DM severity. METHODS:We id...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2585

    authors: Tsai CL,Lin CL,Wu YY,Shieh DC,Sung FC,Kao CH

    更新日期:2015-02-01 00:00:00

  • Nested case-control data analysis using weighted conditional logistic regression in The Environmental Determinants of Diabetes in the Young (TEDDY) study: A novel approach.

    abstract:BACKGROUND:A nested case-control (NCC) design within a prospective cohort study can realize substantial benefits for biomarker studies. In this context, it is natural to consider the sample availability in the selection of controls to minimize data loss when implementing the design. However, this violates the randomnes...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.3204

    authors: Lee HS,Lynch KF,Krischer JP,TEDDY Study Group.

    更新日期:2020-01-01 00:00:00

  • Toxin-based selection of insulin-producing cells with improved defense properties for islet cell transplantation.

    abstract::Insulin-producing pancreatic beta-cells are known to be extremely susceptible to destruction, primarily by autoimmune mechanisms, infectious agents, and by chemical toxins that cause overt type I diabetes. As development of highly protected insulin-producing cells would be important for successful cell therapy of diab...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,评审

    doi:10.1002/dmrr.545

    authors: Bloch K,Vardi P

    更新日期:2005-05-01 00:00:00

  • Metabolic syndrome and pre-diabetes contribute to racial disparities in breast cancer outcomes: hypothesis and proposed pathways.

    abstract:BACKGROUND:Women with obesity and type 2 diabetes (T2D) are at greater risk of dying from breast cancer than women without these conditions. Obesity and T2D are associated with insulin resistance and endogenous hyperinsulinemia and are more common in Black women. There is increasing disparity in breast cancer mortality...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2795

    authors: Gallagher EJ,LeRoith D,Franco R,Antoniou IM,Nayak A,Livaudais-Toman J,Bickell NA

    更新日期:2016-10-01 00:00:00

  • Diabetic fatty liver disease is associated with specific changes in blood-borne markers.

    abstract:BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) can lead to cirrhosis and hepatocellular carcinoma and is strongly associated with obesity and insulin resistance. The aim of this study was to assess if plasma markers associated with NAFLD are increased in people with concomitant diabetes compared with those withou...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2269

    authors: Sharma S,Barrett F,Adamson J,Todd A,Megson IL,Zentler-Munro PL,MacRury SM

    更新日期:2012-05-01 00:00:00

  • Renin angiotensin system inhibitors may attenuate low LDL cholesterol-related cancer risk in type 2 diabetes.

    abstract:BACKGROUND:In type 2 diabetes (T2D), copresence of low-density lipoprotein cholesterol (LDL-C) < 2.8 mmol/L with triglyceride < 1.7 mmol/L or with albuminuria synergistically increased cancer risk. We tested whether use of renin angiotensin system inhibitors attenuated the increased cancer risk associated with these tw...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2504

    authors: Yang X,Ma RC,So WY,Wang Y,Kong AP,Ozaki R,Xu G,Chan JC

    更新日期:2014-07-01 00:00:00

  • Long-term diabetic complications may be ameliorated by targeting Rho kinase.

    abstract::This review addresses the roles of Rho/Rho-kinase (ROCK) pathway in the pathogenesis of diabetes complications. Diabetes can cause many serious complications and can result in physical disability or even increased mortality. However, there are not many effective ways to treat these complications. The small guanosine-5...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,评审

    doi:10.1002/dmrr.1182

    authors: Zhou H,Li Y

    更新日期:2011-05-01 00:00:00

  • Guidelines on use of interventions to enhance healing of chronic foot ulcers in diabetes (IWGDF 2019 update).

    abstract::The International Working Group on the Diabetic Foot (IWGDF) has published evidence-based guidelines on the prevention and management of diabetic foot disease since 1999. In conjunction with advice from internal and external reviewers and expert consultants in the field, this update is based on a systematic review of ...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,评审

    doi:10.1002/dmrr.3283

    authors: Rayman G,Vas P,Dhatariya K,Driver V,Hartemann A,Londahl M,Piaggesi A,Apelqvist J,Attinger C,Game F,International Working Group on the Diabetic Foot (IWGDF).

    更新日期:2020-03-01 00:00:00

  • The use of antimicrobials as adjuvant therapy for the treatment of obesity and insulin resistance: Effects and associated mechanisms.

    abstract::The intestinal microbiota has come to be considered an additional risk factor for the development of metabolic diseases. Considering the potential role of antimicrobials as modulators of the intestinal microbiota, they have been investigated for use in the adjuvant treatment of obesity and insulin resistance (IR). In ...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,评审

    doi:10.1002/dmrr.3014

    authors: Dos Reis SA,do Carmo Gouveia Peluzio M,Bressan J

    更新日期:2018-09-01 00:00:00

  • Association of ELMO1 gene polymorphism and diabetic nephropathy among Egyptian patients with type 2 diabetes mellitus.

    abstract:BACKGROUND AND OBJECTIVE:Diabetic nephropathy (DN) is the most common cause of end stage renal failure or even death among patients with type 2 diabetes mellitus. Genetic predisposition is widely studied among these patients to identify manageable aspects of the disease pathogenesis. This study was carried out to test ...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.3299

    authors: Bayoumy NMK,El-Shabrawi MM,Leheta OF,Abo El-Ela AEM,Omar HH

    更新日期:2020-07-01 00:00:00

  • Preventing diabetes in women with gestational diabetes.

    abstract::The immediate consequences of gestational diabetes on pregnancy are well known but the complications decades later for the mother and child are just now emerging. This trio of papers discuss the long-term consequences of gestational diabetes, the importance of screening this high risk group of women for type 2 diabete...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 社论

    doi:10.1002/dmrr.2280

    authors: Feig D

    更新日期:2012-05-01 00:00:00

  • Association of serum 25-hydroxyvitamin D with type 2 diabetes and markers of insulin resistance in a general older population in Finland.

    abstract:BACKGROUND:Vitamin D insufficiency and type 2 diabetes are both common in Finland, and low vitamin D status has been suggested as a risk factor for type 2 diabetes. Our aim was to study the associations between serum 25-hydroxyvitamin D [25(OH)D], a marker of vitamin D status, and glucose homeostasis and type 2 diabete...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2286

    authors: Hurskainen AR,Virtanen JK,Tuomainen TP,Nurmi T,Voutilainen S

    更新日期:2012-07-01 00:00:00

  • Platelet mean volume, distribution width, and count in type 2 diabetes, impaired fasting glucose, and metabolic syndrome: a meta-analysis.

    abstract:BACKGROUND:Platelet activation contributes to cardiovascular disease (CVD), the main complication of type 2 diabetes mellitus (T2DM) and pre-diabetic conditions. Mean platelet volume is an easy-to-measure platelet parameter that has been associated with CVD. We sought to assess mean platelet volume, platelet distributi...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章,meta分析,评审

    doi:10.1002/dmrr.2625

    authors: Zaccardi F,Rocca B,Pitocco D,Tanese L,Rizzi A,Ghirlanda G

    更新日期:2015-05-01 00:00:00

  • Neck circumference is correlated with triglycerides and inversely related with HDL cholesterol beyond BMI and waist circumference.

    abstract:BACKGROUND:Neck circumference, beyond a measure of obesity, is a unique fat depot with increasing significance. This study aimed to investigate the association between neck circumference and biomarkers, indicators of cardiovascular risk. METHODS:During 2009, 490 volunteers (46 ± 16 years, 40% men) were consecutively e...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2369

    authors: Vallianou NG,Evangelopoulos AA,Bountziouka V,Vogiatzakis ED,Bonou MS,Barbetseas J,Avgerinos PC,Panagiotakos DB

    更新日期:2013-01-01 00:00:00

  • Prevalence of undiagnosed dysglycemia in an emergency department observation unit.

    abstract:BACKGROUND:The proposed 2015 US Preventive Services Task Force guidelines recommend diabetes screening for individuals ≥45 years or demonstrating other risk factors for dysglycemia. Still, many patients with dysglycemia remain undiagnosed, and opportunities for early intervention are lost. METHODS:To test novel approa...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.2674

    authors: Silverman RA,Schleicher MG,Valente CJ,Kim M,Romanenko Y,Schulman RC,Tiberio A,Greenblatt B,Rentala M,Salvador-Kelly AV,Kwon NS,Jornsay DL

    更新日期:2016-01-01 00:00:00

  • Impact of unhealthy childhood and unfavorable parents' characteristics on adiposity in schoolchildren.

    abstract:BACKGROUND:Childhood obesity is encouraged by low physical activity (PA), time spent using screens (screen time, ST), and by sugar-sweetened beverage consumption (SSBc). It is also influenced by unfavorable parents' characteristics, such as a high body mass index (BMI) and low education level (EL). Our aim was to evalu...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.3199

    authors: Vinciguerra F,Tumminia A,Roppolo F,Romeo LC,La Spina N,Baratta R,Parrino C,Sciacca L,Vigneri R,Frittitta L

    更新日期:2019-11-01 00:00:00

  • Fulminant type 1 diabetes mellitus exhibits distinct clinical and autoimmunity features from classical type 1 diabetes mellitus in Chinese.

    abstract:BACKGROUND:fulminant type 1 diabetes mellitus (T1DM) is characterized by abrupt onset of hyperglycemia and rapid progression to ketoacidosis. This study aimed at examining the clinical and autoimmunity features of fulminant T1DM in Chinese. METHODS:a total of 24 patients with fulminant T1DM and 48 classical autoimmune...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.1148

    authors: Zheng C,Zhou Z,Yang L,Lin J,Huang G,Li X,Zhou W,Wang X,Liu Z

    更新日期:2011-01-01 00:00:00

  • Nonenzymatic glycation of high-density lipoprotein impairs its anti-inflammatory effects in innate immunity.

    abstract:AIMS/HYPOTHESIS:In type 2 diabetes mellitus (T2DM), the abnormal protein and lipid composition of diabetic high-density lipoprotein (HDL) could impair its anti-inflammatory functions. Whether nonenzymatic glycation directly impaired the anti-inflammatory effects of HDL in innate immunity remained unclear. METHODS:Huma...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.1297

    authors: Liu D,Ji L,Zhang D,Tong X,Pan B,Liu P,Zhang Y,Huang Y,Su J,Willard B,Zheng L

    更新日期:2012-02-01 00:00:00

  • The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes.

    abstract:BACKGROUND:The aim of the study is to assess the relationship between the shape of plasma glucose concentration during the OGTT and future risk for T2DM. METHODS:2445 non-diabetic subjects from the Botnia study received an OGTT at baseline and after 7-8 years of follow-up. RESULTS:NGT and IFG subjects who returned th...

    journal_title:Diabetes/metabolism research and reviews

    pub_type: 杂志文章

    doi:10.1002/dmrr.1084

    authors: Abdul-Ghani MA,Lyssenko V,Tuomi T,Defronzo RA,Groop L

    更新日期:2010-05-01 00:00:00