Metformin restores electrophysiology of small conductance calcium-activated potassium channels in the atrium of GK diabetic rats.

abstract：BACKGROUND:Hyperlipidemia and hypertension are well-established risk factors for recurrent cardiovascular events among patients with ischemic heart disease (IHD). Despite national recommendations, concordance with guidelines for LDL cholesterol and blood pressure remains inadequate. The objectives of this study were to...

journal_title：BMC cardiovascular disorders

authors： Ho PM,Prochazka AV,Magid DJ,Sales AE,Grunwald GK,Hammermeister KE,Rumsfeld JS

更新日期：2006-02-09 00:00:00

abstract：BACKGROUND:Novel pro-inflammatory and anti-inflammatory derivatives from adipose tissue, known as adipokines, act as metabolic factors. The aim of this study was to analyse the secreted expression of different adipo/cytokines in secretomes of unstable carotid atherosclerotic plaque versus non-atherosclerotic mammary ar...

journal_title：BMC cardiovascular disorders

authors： Auguet T,Aragonès G,Guiu-Jurado E,Berlanga A,Curriu M,Martinez S,Alibalic A,Aguilar C,Camara ML,Hernández E,Ruyra X,Martín-Paredero V,Richart C

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:There have been suggestions of an association between Chlamydia pneumoniae, chlamydial heat shock protein (Ch-hsp) 60 and human heat shock protein (h-hsp) 60 infection sero-status and development of secondary cardiovascular events. Patients with diabetes might be at higher risk since they are prone to infect...

journal_title：BMC cardiovascular disorders

authors： Guech-Ongey M,Brenner H,Twardella D,Rothenbacher D

更新日期：2006-04-12 00:00:00

abstract：BACKGROUND:The ten year probability of cardiovascular events can be calculated, but many people are unaware of their risk and unclear how to reduce it. The aim of this study was to assess whether a community based intervention, for men and women aged between 45 and 64 years without pre-existing coronary heart disease, ...

journal_title：BMC cardiovascular disorders

authors： Richardson G,van Woerden HC,Morgan L,Edwards R,Harries M,Hancock E,Sroczynsk S,Bowley M

更新日期：2008-07-26 00:00:00

abstract：BACKGROUND:Aortic regurgitation (AR) is a valvular disease that can lead to systolic heart failure. Treatment options besides cardiac surgery are limited and consequently severe AR is associated with higher mortality and morbidity when not operated. In this investigation, we examined the effects of a novel cardiac myos...

journal_title：BMC cardiovascular disorders

authors： El-Oumeiri B,Mc Entee K,Annoni F,Herpain A,Vanden Eynden F,Jespers P,Van Nooten G,van de Borne P

更新日期：2018-05-21 00:00:00

abstract：BACKGROUND:Reported effects of obesity on the extent of angiographic coronary artery disease(CAD) have been inconsistent. The present study aimed to investigate the relationships between the indices of obesity and other anthropometric markers with the extent of CAD. METHODS:This study was conducted on 1008 consecutive...

journal_title：BMC cardiovascular disorders

authors： Nabati M,Moosazadeh M,Soroosh E,Shiraj H,Gholami M,Ghaemian A

更新日期：2020-05-29 00:00:00

abstract：BACKGROUND:There are limited data regarding the impact of bioresorbable polymer drug eluting stent (BP-DES) compared to durable polymer drug eluting stent (DP-DES) in patients treated with percutaneous coronary intervention using ultrathin stents in left main or bifurcations. METHODS:In the RAIN registry (ClinicalTria...

journal_title：BMC cardiovascular disorders

authors： Iannaccone M,Barbero U,De Benedictis M,Imori Y,Quadri G,Trabattoni D,Ryan N,Venuti G,Montabone A,Wojakowski W,Rognoni A,Helft G,Parma R,De Luca L,Autelli M,Boccuzzi G,Mattesini A,Templin C,Cerrato E,Wańha W,Smolka

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND:Carotid intima-media thickness (C-IMT) is a reliable predictor of cardiovascular events. We Investigated the relationship between markers of glycemia and C-IMT in intermediate-risk cardiovascular patients. METHODS:This study analyzed 427 subjects, aged 35 to 74 years (mean, 60.3 ± 8.5 years), 55 % women, en...

journal_title：BMC cardiovascular disorders

authors： Gomez-Marcos MA,Gomez-Sanchez L,Patino-Alonso MC,Recio-Rodriguez JI,Regalado NG,Ramos R,Marti R,Agudo-Conde C,Rodriguez-Sanchez E,Maderuelo-Fernandez JA,Garcia-Ortiz L,MARK Group.

更新日期：2016-10-28 00:00:00

abstract：BACKGROUND:Timely restoration of bloodflow acute ST-segment elevation myocardial infarction (STEMI) reduces myocardial damage and improves prognosis. The objective of this study was describe the association of demographic factors with hospitalisation rates for STEMI and time to angiography, Percutaneous Coronary Interv...

journal_title：BMC cardiovascular disorders

authors： Taylor LK,Nelson MA,Gale M,Trevena J,Brieger DB,Winch S,Cretikos MA,Newman LA,Phung HN,Faddy SC,Kelly PM,Chant K

更新日期：2020-05-14 00:00:00

abstract：BACKGROUND:A permanently indwelling filter in the inferior vena cava (IVC) may induce caval thrombosis, which could develop and evolve from an acute to a chronic phase. The differential diagnosis of acute and chronic thromboses determines the treatment strategy. The role of computed tomography (CT) in diagnosing acute ...

journal_title：BMC cardiovascular disorders

authors： Chen L,Shi W,Gu J,He X,Lou W

更新日期：2018-04-11 00:00:00

abstract：BACKGROUND:Epicardial adipose tissue (EAT) remodeling and adipocytokines are associated with structural remodeling in atrial fibrillation (AF). However, the role of omentin-1, a novel adipocytokine, in structural remodeling remains unknown. METHODS:Hematoxylin and eosin (H&E) and Masson's trichrome stains were used to...

journal_title：BMC cardiovascular disorders

authors： Chen Y,Liu F,Han F,Lv L,Tang CE,Xie Z,Luo F

更新日期：2020-05-06 00:00:00

abstract：BACKGROUND:In recent years, Ecological Momentary Assessment (EMA) has expanded rapidly in healthcare research but its application specifically to the field of cardiology has been limited. This study presents essential information concerning the feasibility and validity of EMA in patients with acute coronary syndrome. ...

journal_title：BMC cardiovascular disorders

authors： Jean FAM,Sibon I,Husky M,Couffinhal T,Swendsen J

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Renal denervation (RDN) targeting the sympathetic nerves in the renal arterial adventitia as a treatment of resistant hypertension can cause endothelial injury and vascular wall injury. This study aims to evaluate the risk of atherosclerosis induced by RDN in renal arteries. METHODS:A total of 15 minipigs w...

journal_title：BMC cardiovascular disorders

authors： Su E,Zhao L,Yang X,Zhu B,Liu Y,Zhao W,Wang X,Qi D,Zhu L,Gao C

更新日期：2020-04-16 00:00:00

abstract：BACKGROUND:Ventricular strain measurements vary depending on cardiac chamber (left ventricle [LV] or right ventricle [RV]), type of strain (longitudinal, circumferential, or radial), ventricular level (basal, mid, or apical), myocardial layer (endocardial or epicardial), and software used for analysis, among other demo...

journal_title：BMC cardiovascular disorders

authors： Xia H,Yeung DF,Di Stefano C,Cha SS,Pellikka PA,Ye Z,Thaden JJ,Villarraga HR

更新日期：2020-06-05 00:00:00

abstract：BACKGROUND:To explore why bicuspid aortic stenosis has certain clinical differences from the tricuspid morphology, we evaluated the metabolomics profile involved in bicuspid aortic valve (BAV) aortic stenosis prior to and after transcatheter aortic valve replacement (TAVR) in comparison with tricuspid aortic valve (TAV...

journal_title：BMC cardiovascular disorders

authors： Xiong TY,Liu C,Liao YB,Zheng W,Li YJ,Li X,Ou Y,Wang ZJ,Wang X,Li CM,Zhao ZG,Feng Y,Liu XJ,Chen M

更新日期：2020-05-18 00:00:00

abstract：BACKGROUND:Fabry disease is caused by mutations in the α-galactosidase A (GLA) gene, which is located in X-chromosome coding for the lysosomal enzyme of GLA. Among many gene mutations, E66Q mutation is under discussion for its pathogenicity because there is no clinical report showing pathological evidence of Fabry dise...

journal_title：BMC cardiovascular disorders

authors： Oikawa M,Sakamoto N,Kobayashi A,Suzuki S,Yoshihisa A,Yamaki T,Nakazato K,Suzuki H,Saitoh S,Kiko Y,Nakano H,Hayashi T,Kimura A,Takeishi Y

更新日期：2016-05-10 00:00:00

abstract：BACKGROUND:There is a controversy about the association between vitamin D and cardiovascular diseases (CVDs). The effect of serum 25-OH-vitD on the risk of CVDs was evaluated. METHODS:Major electronic databases including Scopus, Science Direct, and PubMed were searched. All prospective cohort studies on the relationsh...

journal_title：BMC cardiovascular disorders

authors： Gholami F,Moradi G,Zareei B,Rasouli MA,Nikkhoo B,Roshani D,Ghaderi E

更新日期：2019-11-07 00:00:00

abstract：BACKGROUND:Long term β-blocker therapy after myocardial infarction (MI) reduces mortality and recurrent MI but evidence for this treatment predates contemporary acute coronary care. β-blocker treatment is a key quality of care indicator in the Swedish national quality register for acute coronary care, Riks-HIA. Between...

journal_title：BMC cardiovascular disorders

authors： Hagsund T,Olsson SE,Smith JG,Madsen Hardig B,Wagner H

更新日期：2020-04-09 00:00:00

abstract：BACKGROUND:Genetic variation at 1p13 modulates serum lipid levels and the risk of coronary heart disease through the regulation of serum lipid levels. Here we investigate if the interaction between genetic variants at 1p13 and serum lipid levels affects the risk of non-fatal myocardial infarction (MI) in the Stockholm ...

journal_title：BMC cardiovascular disorders

authors： Gigante B,Leander K,Vikström M,Ye S,de Faire U

更新日期：2012-10-16 00:00:00

abstract：BACKGROUND:Ectonucleotidase plays an important role in the regulation of cardiac function by controlling extracellular levels of adenine nucleotides and adenosine. To determine the influence of ischemia-reperfusion injury on ectonucleotidase activity in coronary vascular bed, we compared the metabolic profile of adenin...

journal_title：BMC cardiovascular disorders

authors： Takahashi-Sato K,Murakawa M,Kimura J,Ito MA,Matsuoka I

更新日期：2013-07-28 00:00:00

abstract：BACKGROUND:Heart valve surgery outcomes are unknown in middle-income countries and thus cannot be used in health system decision making processes. This study estimated in-hospital mortality and medium and long-term survival. METHODS:This was a retrospective study of 78,806 patients who underwent heart valve surgery be...

journal_title：BMC cardiovascular disorders

authors： de Aquino Xavier RM,Azevedo VMP,Godoy PH,Migowski A,Ribeiro ALP,Chaves RBM,Correia MG,de Aquino Xavier C,de Aquino Hashimoto L,Weksler C,Silva NASE

更新日期：2017-12-28 00:00:00

abstract：BACKGROUND:Suspected nonischemic cardiomyopathy (NICM) is a common clinical setting with highly variable prognosis. Early noninvasive risk-stratification is important for justification of invasive examinations, specific treatment and patient surveillance. We studied the additional prognostic value of late gadolinium en...

journal_title：BMC cardiovascular disorders

authors： Pöyhönen P,Kivistö S,Holmström M,Hänninen H

更新日期：2014-08-27 00:00:00

abstract：BACKGROUND:In a previous study, we found that titrating clopidogrel maintenance doses (MDs) according to vasodilator-stimulated phosphoprotein (VASP) monitoring minimised the rate of major adverse cardiovascular and cerebral events (MACCE) after percutaneous coronary intervention (PCI) without increasing bleeding in pa...

journal_title：BMC cardiovascular disorders

authors： Hu C,Zhang X,Liu Y,Gao Y,Zhao X,Zhou H,Luo Y,Liu Y,Wang X

更新日期：2018-06-18 00:00:00

abstract：BACKGROUND:Screening with ankle-brachial index (ABI) measurement could be clinically relevant to avoid cardiovascular events in subjects with asymptomatic atherosclerosis. To assess the practical impact of guidelines regarding the use of ABI as a screening tool in general practice, the corresponding number needed to sc...

journal_title：BMC cardiovascular disorders

authors： Bendermacher BL,Teijink JA,Willigendael EM,Bartelink ML,Peters RJ,Langenberg M,Büller HR,Prins MH

更新日期：2012-07-30 00:00:00

abstract：BACKGROUND:Increased arterial stiffness (iAS) and microalbuminuria (MAU), which may occur simultaneously or separately in the general population and share similar risk factors, are markers of macro- and microvascular injuries. Our research investigated the comorbidity of iAS and MAU in the middle-aged population and ex...

journal_title：BMC cardiovascular disorders

authors： Miao R,Wu L,Ni P,Zeng Y,Chen Z

更新日期：2018-05-04 00:00:00

abstract：BACKGROUND:Air embolus penetrating into heart chamber as a complication during percutaneous radiofrequency catheter ablation has been infrequently reported. CASE PRESENTATION:A 55-year-old man with dextrocardia who suffered from abdominal pain was suspected to have multiple arterial thromboembolisms, which might have ...

journal_title：BMC cardiovascular disorders

authors： Wang YF,Cen XJ,Yu JW,Qu BM,Wang LH

更新日期：2017-06-02 00:00:00

abstract：BACKGROUND:The interventional left atrial appendage closure (LAAC) is a guideline-conform alternative to oral anticoagulation (OAC) in non-valvular atrial fibrillation patients with OAC ineligibility. It was aimed to directly compare two contemporary devices in a real-world patient population. METHODS:LAAC was conduct...

journal_title：BMC cardiovascular disorders

authors： Fastner C,Hoffmann L,Aboukoura M,Behnes M,Lang S,Borggrefe M,Akin I,Nienaber CA

更新日期：2018-08-20 00:00:00

abstract：BACKGROUND:Disease-management programmes including patient education have promoted improvement in outcome for patients with heart failure. However, there is sparse evidence concerning which component is essential for success, and very little is known regarding the validity of methods or material used for the education....

journal_title：BMC cardiovascular disorders

authors： Linné AB,Liedholm H

更新日期：2006-06-24 00:00:00

abstract：BACKGROUND:The aim of this study was to systematically assess the efficacy and safety of mineralocorticoid receptor antagonists (MRAs) for patients with heart failure (HF) and diabetes mellitus (DM). METHODS:We conducted a comprehensive search for controlled studies that evaluated the efficacy and safety of MRAs in pa...

journal_title：BMC cardiovascular disorders

authors： Chen MD,Dong SS,Cai NY,Fan MD,Gu SP,Zheng JJ,Yin HM,Zhou XH,Wang LX,Li CY,Zheng C

更新日期：2016-01-29 00:00:00

abstract：BACKGROUND:Metabolic syndrome is associated with cardio-metabolic risk factors and lipid abnormalities. Previous studies evaluated the dietary habits and nutrient intakes among patients with metabolic syndrome; however the association between metabolic risk factors and adiponectin with dietary diversity score (DDS) in ...

journal_title：BMC cardiovascular disorders

authors： Farhangi MA,Jahangiry L

更新日期：2018-04-17 00:00:00