Abstract：
BACKGROUND:The interventional left atrial appendage closure (LAAC) is a guideline-conform alternative to oral anticoagulation (OAC) in non-valvular atrial fibrillation patients with OAC ineligibility. It was aimed to directly compare two contemporary devices in a real-world patient population. METHODS:LAAC was conducted in two centres between 2010 and 2014 as well as between 2014 and 2017, respectively, in a standard fashion based on the specific manufacturer's recommendations. Baseline characteristics, procedural data and event rates during intra-hospital and 6 months follow-up were registered in a retrospective approach, and analysed in device-related groups. RESULTS:A total of 189 patients presented for LAAC device implantation. Baseline characteristics were mostly evenly distributed. In 148 patients, a Watchman™ device (Boston Scientific, Natick, MA, USA) was successfully implanted, an Amplatzer™ Amulet™ (St. Jude Medical, St. Paul, MN, USA) in 34 patients (96.1 and 97.1%, respectively; p = 1.00). Major access site bleedings were more frequent in the Amplatzer™ Amulet™ group (8.9 versus 1.4%; p = 0.046). No intra-hospital thromboembolic event was present. During 6 months follow-up, peri-device leaks > 5 mm and thromboembolic events were uncommon (each p = n.s.). CONCLUSIONS:While procedural success was equally high with both contemporary devices, complications during follow-up were rare, and evenly distributed.
journal_name
BMC Cardiovasc Disordjournal_title
BMC cardiovascular disordersauthors
Fastner C,Hoffmann L,Aboukoura M,Behnes M,Lang S,Borggrefe M,Akin I,Nienaber CAdoi
10.1186/s12872-018-0899-9subject
Has Abstractpub_date
2018-08-20 00:00:00pages
171issue
1issn
1471-2261pii
10.1186/s12872-018-0899-9journal_volume
18pub_type
杂志文章,多中心研究abstract：BACKGROUND:There is limited information about any association between the onset of atrial fibrillation (AF) and the presence of valvular disease. METHODS:We retrospectively examined 940 patients in sinus rhythm, examined by echocardiography in 1996. During 11 years of follow-up, we assessed the incidence of AF and out...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-12-92
更新日期：2012-10-18 00:00:00
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journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-019-1202-4
更新日期：2019-10-07 00:00:00
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journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
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更新日期：2012-04-25 00:00:00
abstract：BACKGROUND:This study aims to evaluate the ADL(activity of daily living) of patients with acute cerebral infarction through BI scoring, in order to observe its predictive value in the prognosis of these patients. METHODS:According to the inclusion and exclusion criteria, patients with acute anterior circulation cerebr...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-019-01306-1
更新日期：2020-01-13 00:00:00
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journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,评审
doi：10.1186/1471-2261-1-2
更新日期：2001-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1186/s12872-017-0548-8
更新日期：2017-05-08 00:00:00
abstract：BACKGROUND:Microsomal transfer protein inhibitors (MTPi) have the potential to be used as a drug to lower plasma lipids, mainly plasma triglycerides (TG). However, studies with animal models have indicated that MTPi treatment results in the accumulation of hepatic TG. The purpose of this study was to evaluate whether J...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/1471-2261-5-30
更新日期：2005-09-27 00:00:00
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pub_type： 杂志文章
doi：10.1186/s12872-015-0084-3
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abstract：BACKGROUND:The aim of this study was to systematically assess the efficacy and safety of mineralocorticoid receptor antagonists (MRAs) for patients with heart failure (HF) and diabetes mellitus (DM). METHODS:We conducted a comprehensive search for controlled studies that evaluated the efficacy and safety of MRAs in pa...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,meta分析,评审
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更新日期：2016-01-29 00:00:00
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journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-017-0512-7
更新日期：2017-03-14 00:00:00
abstract：BACKGROUND:Hypertension is a growing public health problem in many developing countries including Ethiopia. However, its prevention and control has not yet received due attention. This study aimed to determine the prevalence and associated factors of hypertension among adults in Gondar city, North-West Ethiopia. METHO...
journal_title：BMC cardiovascular disorders
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abstract：BACKGROUND:In a previous study, we found that titrating clopidogrel maintenance doses (MDs) according to vasodilator-stimulated phosphoprotein (VASP) monitoring minimised the rate of major adverse cardiovascular and cerebral events (MACCE) after percutaneous coronary intervention (PCI) without increasing bleeding in pa...
journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12872-018-0853-x
更新日期：2018-06-18 00:00:00
abstract：BACKGROUND:Aneurysmal subarachnoid hemorrhage is a life- threatening condition with high rate of disability and mortality. Apolipoprotein E (APOE) and Factor XIIIA (F13A) genes are involved in the pathogenetic mechanism of aneurysmal subarachnoid haemorrhage (aSAH). We evaluated the association of promoter methylation ...
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pub_type： 杂志文章
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更新日期：2019-07-17 00:00:00
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更新日期：2021-01-15 00:00:00
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更新日期：2016-11-07 00:00:00
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journal_title：BMC cardiovascular disorders
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2018-06-28 00:00:00
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pub_type： 杂志文章,meta分析,评审
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更新日期：2012-08-19 00:00:00
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pub_type： 杂志文章,meta分析
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更新日期：2017-04-04 00:00:00
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更新日期：2018-03-16 00:00:00
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pub_type： 杂志文章,多中心研究
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更新日期：2013-08-23 00:00:00
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pub_type： 杂志文章,随机对照试验
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更新日期：2012-09-17 00:00:00
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更新日期：2017-07-11 00:00:00
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journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
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更新日期：2016-05-28 00:00:00
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journal_title：BMC cardiovascular disorders
pub_type： 杂志文章
doi：10.1186/s12872-018-0982-2
更新日期：2019-01-17 00:00:00
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pub_type： 杂志文章,评审
doi：10.1186/1471-2261-12-46
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