Abstract:
BACKGROUND:ST elevation Myocardial infarction is a medical emergency. A variety of noncardiac conditions had been known to mimic the ECG changes that are seen in acute coronary syndrome. Although the common ECG changes that are documented with raised intracranial pressure are T inversions, prolongation of QT interval and sinus bradycardia, ST elevation or depression, arrhythmias and prominent U waves have also been recognized. However, ST elevations in association with primary intracranial tumours are rarely reported. CASE PRESENTATION:A 68-year-old female patient with a large left sided frontoparietal sphenoidal ridge meningioma with mass effect developed sudden onset shortness of breath while awaiting surgery. Her ECG showed ST segment elevations in the inferior leads along with reciprocal T inversions in anterior leads. The patient was treated with dual antiplatelet therapy and unfractionated heparin. The ST elevations in the ECG remained static and the cardiac Troponin assay was repeatedly negative. 2D ECHO, coronary angiogram and CT pulmonary angiography were normal. The repeat noncontract CT scan of the brain revealed two small areas of haemorrhage in the tumour. CONCLUSION:The two mechanisms for ECG changes described in subarachnoid haemorrhage are the neurogenic stunned myocardium due to the catecholamine surge on the myocytes and stress cardiomyopathy. The same mechanisms could be the reasons for the ECG changes seen in intracranial tumours. These ECG changes could be easily misdiagnosed as acute coronary syndrome. This case emphasizes the importance of the cardiac biomarkers, 2D ECHO and coronary angiogram when confronted with such a diagnostic dilemma. Thus a more holistic analysis should be practiced in diagnosing acute coronary events in patients with intracranial pathologies to obviate a myriad of unnecessary investigations, interventions, costly treatment strategies which may well be detrimental to the patient.
journal_name
BMC Cardiovasc Disordjournal_title
BMC cardiovascular disordersauthors
Yogendranathan N,Herath HM,Pahalagamage SP,Kulatunga Adoi
10.1186/s12872-017-0525-2subject
Has Abstractpub_date
2017-04-04 00:00:00pages
91issue
1issn
1471-2261pii
10.1186/s12872-017-0525-2journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Both systemic-pulmonary shunt and arterial duct stent could be the palliation of duct-dependent pulmonary circulation. We aimed to compare the safety and efficacy of the two approaches. METHODS:The PubMed, EMBASE, and Cochrane Library databases were searched through December 2019 for studies comparing stent...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01817-2
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:Despite the potentially life-saving benefits of the implantable cardioverter-defibrillator (ICD), a significant group of patients experiences emotional distress after ICD implantation. Different psychosocial interventions have been employed to improve this condition, but previous reviews have suggested that ...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章,评审
doi:10.1186/1471-2261-9-56
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abstract:BACKGROUND:This study aims to evaluate the ADL(activity of daily living) of patients with acute cerebral infarction through BI scoring, in order to observe its predictive value in the prognosis of these patients. METHODS:According to the inclusion and exclusion criteria, patients with acute anterior circulation cerebr...
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doi:10.1186/s12872-019-01306-1
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journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-015-0005-5
更新日期:2015-02-25 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2016-11-18 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1186/s12872-018-0965-3
更新日期:2019-01-03 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1186/s12872-017-0528-z
更新日期:2017-04-04 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12872-020-01605-y
更新日期:2020-07-07 00:00:00
abstract:BACKGROUND:The platelet to lymphocyte ratio (PLR), an indirect inflammatory biomarker, has been recently demonstrated to be associated with severity of coronary artery disease. In the present study, we sought to investigate whether PLR is associated with vulnerable plaque characteristics of non-culprit lesions in patie...
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pub_type: 杂志文章
doi:10.1186/s12872-017-0618-y
更新日期:2017-07-03 00:00:00
abstract:BACKGROUND:Percutaneous coronary intervention (PCI) is a common treatment for patients with coronary heart disease, and intra-stent restenosis (ISR) is a serious complication after PCI. It's necessary to identify the potential risk factors to provide evidence for the prevention of ISR. METHODS:The patients who underwe...
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pub_type: 杂志文章
doi:10.1186/s12872-020-01798-2
更新日期:2020-12-04 00:00:00
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journal_title:BMC cardiovascular disorders
pub_type: 杂志文章,meta分析
doi:10.1186/s12872-019-1079-2
更新日期:2019-06-03 00:00:00
abstract:BACKGROUND:Atherosclerosis (AT) is a chronic inflammatory disease characterized by the accumulation of inflammatory cells, lipoproteins and fibrous tissue in the walls of arteries. AT is the primary cause of heart attacks and stroke and is the leading cause of death in Western countries. To date, the pathogenesis of AT...
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pub_type: 杂志文章
doi:10.1186/1471-2261-13-4
更新日期:2013-01-16 00:00:00
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pub_type: 杂志文章,meta分析,评审
doi:10.1186/s12872-017-0598-y
更新日期:2017-06-20 00:00:00
abstract:BACKGROUND:N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a potential biomarker for monitoring the status of heart failure. However, the optimal monitoring interval of NT-proBNP is unknown. This study sought to investigate the minimal informative monitoring interval of NT-proBNP in patients with stable chroni...
journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01537-7
更新日期:2020-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12872-016-0236-0
更新日期:2016-04-02 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-2261-11-67
更新日期:2011-11-09 00:00:00
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pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章,评审
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更新日期:2019-12-12 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12872-017-0514-5
更新日期:2017-03-15 00:00:00
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pub_type: 杂志文章
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journal_title:BMC cardiovascular disorders
pub_type: 杂志文章,多中心研究
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更新日期:2007-10-31 00:00:00
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pub_type: 杂志文章
doi:10.1186/s12872-017-0718-8
更新日期:2017-12-04 00:00:00
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journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/1471-2261-12-79
更新日期:2012-09-24 00:00:00
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journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-016-0400-6
更新日期:2016-11-17 00:00:00
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journal_title:BMC cardiovascular disorders
pub_type: 杂志文章
doi:10.1186/s12872-020-01699-4
更新日期:2020-09-11 00:00:00
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pub_type: 杂志文章
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