The minimal informative monitoring interval of N-terminal pro-B-type natriuretic peptide in patients with stable heart failure.

Abstract:

BACKGROUND:N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a potential biomarker for monitoring the status of heart failure. However, the optimal monitoring interval of NT-proBNP is unknown. This study sought to investigate the minimal informative monitoring interval of NT-proBNP in patients with stable chronic heart failure. METHODS:This retrospective cohort study included patients who were admitted due to heart failure and subsequently followed with serial NT-proBNP measurements in a tertiary hospital. We analyzed NT-proBNP measured between six months after discharge and the earliest timepoint of: an alteration of medication regimen, readmission due to worsening of heart failure, or all-cause death. To distinguish progression of the disease from biological variability and measurement error, the signal-to-noise ratio method was applied with a random-effects model. RESULTS:In the 368 patients included, NT-proBNP was measured for a median 6 times. In the random-effects model, signal (progression of disease) exceeded noise (biological variability and measurement error) at 7.9 months (95% confidence interval [CI]: 5.1-9.6), while noise corresponded to a 61% increase from baseline. In stratified analysis using the AHEAD risk score, the minimal informative monitoring interval shortened as the risk score increased (0-1 point: 12.2 months [95%CI: 10.3-14.4]; 2-3 points: 8.0 months [95%CI: 6.8-9.7]; 4-5 points: 3.3 months [95%CI: 3.0-3.8]). CONCLUSIONS:In patients with stable chronic heart failure, the minimal informative monitoring interval of NT-proBNP measurement was 7.9 months in the current population, which varied with underlying risks. The optimal monitoring interval could be lengthened for patients at lower risks.

journal_name

BMC Cardiovasc Disord

authors

Dai Z,Asano T,Takahashi O,Komiyama N,Ohde S

doi

10.1186/s12872-020-01537-7

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

262

issue

1

issn

1471-2261

pii

10.1186/s12872-020-01537-7

journal_volume

20

pub_type

杂志文章
  • β-blockers after myocardial infarction and 1-year clinical outcome - a retrospective study.

    abstract:BACKGROUND:Long term β-blocker therapy after myocardial infarction (MI) reduces mortality and recurrent MI but evidence for this treatment predates contemporary acute coronary care. β-blocker treatment is a key quality of care indicator in the Swedish national quality register for acute coronary care, Riks-HIA. Between...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01441-0

    authors: Hagsund T,Olsson SE,Smith JG,Madsen Hardig B,Wagner H

    更新日期:2020-04-09 00:00:00

  • Ultrasound-targeted microbubble destruction promotes myocardial angiogenesis and functional improvements in rat model of diabetic cardiomyopathy.

    abstract:BACKGROUND:Microvascular insufficiency plays an important role in the development of diabetic cardiomyopathy (DCM), therapeutic angiogenesis has been mainly used for the treatment of ischemic diseases. This study sought to verify the preclinical performance of SonoVue microbubbles (MB) combined ultrasound (US) treatmen...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01815-4

    authors: Zhang X,Tian X,Li P,Zhu H,Zhou N,Fang Z,Yang Y,Jing Y,Yuan J

    更新日期:2021-01-07 00:00:00

  • HYPEST study: profile of hypertensive patients in Estonia.

    abstract:BACKGROUND:More than one third of adult population in Estonia has problems with elevated blood pressure (BP). The Hypertension in Estonia (HYPEST) study represents the country's first hypertension-targeted sample collection aiming to examine the epidemiological and genetic determinants for hypertension (HTN) and relate...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2261-11-55

    authors: Org E,Veldre G,Viigimaa M,Juhanson P,Putku M,Rosenberg M,Tomberg K,Uuetoa T,Laan M

    更新日期:2011-08-31 00:00:00

  • Long-term secondary prevention of acute myocardial infarction (SEPAT) - guidelines adherence and outcome.

    abstract:BACKGROUND:A number of registry studies have reported suboptimal adherence to guidelines for cardiovascular prevention during the first year after acute myocardial infarction (AMI). However, only a few studies have addressed long-term secondary prevention after AMI. This study evaluates prevention guideline adherence a...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-016-0400-6

    authors: Ergatoudes C,Thunström E,Rosengren A,Björck L,Bengtsson Boström K,Falk K,Fu M

    更新日期:2016-11-17 00:00:00

  • Remote noninvasive allograft rejection monitoring for heart transplant recipients: study protocol for the novel evaluation with home electrocardiogram and remote transmission (NEW HEART) study.

    abstract:BACKGROUND:Acute allograft rejection is a major cause of early mortality in the first year after heart transplantation in adults. Although endomyocardial biopsy (EMB) is not a perfect "gold standard" for a correct diagnosis of acute allograft rejection, it is considered the best available test and thus, is the current ...

    journal_title:BMC cardiovascular disorders

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1186/1471-2261-12-14

    authors: Doering LV,Hickey K,Pickham D,Chen B,Drew BJ

    更新日期:2012-03-02 00:00:00

  • A cell culture model using rat coronary artery adventitial fibroblasts to measure collagen production.

    abstract:BACKGROUND:We have developed a rat cell model for studying collagen type I production in coronary artery adventitial fibroblasts. Increased deposition of adventitial collagen type I leads to stiffening of the blood vessel, increased blood pressure, arteriosclerosis and coronary heart disease. Although the source and me...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-7-13

    authors: Jenkins C,Milsted A,Doane K,Meszaros G,Toot J,Ely D

    更新日期:2007-05-08 00:00:00

  • Early changes in myocardial repolarization and coronary perfusion after cardiopulmonary bypass surgery for ASD repair in children.

    abstract:BACKGROUND:In adults, impaired myocardial repolarization and increased risk of arrhythmia are known consequences of open heart surgery. Little is known, however, about post-operative consequences of cardiopulmonary bypass surgery in children. The aim of this study was to assess ventricular repolarization and coronary p...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-13-67

    authors: Aburawi EH,Souid AK,Liuba P,Zoubeidi T,Pesonen E

    更新日期:2013-09-10 00:00:00

  • Do gender differences in primary PCI mortality represent a different adherence to guideline recommended therapy? a multicenter observation.

    abstract:BACKGROUND:It is uncertain whether gender differences in outcome after primary percutaneous coronary intervention (PCI) are only attributable to different baseline characteristics or additional factors. METHODS:Databases of two German myocardial infarction network registries were combined with a total of 1104 consecut...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2261-14-71

    authors: Birkemeyer R,Schneider H,Rillig A,Ebeling J,Akin I,Kische S,Paranskaya L,Jung W,Ince H,Nienaber CA

    更新日期:2014-06-02 00:00:00

  • Cardiac procedures in ST-segment-elevation myocardial infarction - the influence of age, geography and Aboriginality.

    abstract:BACKGROUND:Timely restoration of bloodflow acute ST-segment elevation myocardial infarction (STEMI) reduces myocardial damage and improves prognosis. The objective of this study was describe the association of demographic factors with hospitalisation rates for STEMI and time to angiography, Percutaneous Coronary Interv...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01487-0

    authors: Taylor LK,Nelson MA,Gale M,Trevena J,Brieger DB,Winch S,Cretikos MA,Newman LA,Phung HN,Faddy SC,Kelly PM,Chant K

    更新日期:2020-05-14 00:00:00

  • Cost-of-illness studies in heart failure: a systematic review 2004-2016.

    abstract:BACKGROUND:Heart failure is a major and growing medical and economic problem worldwide as 1-2% of the healthcare budget are spent for heart failure. The prevalence of heart failure has increased over the past decades and it is expected that there will be further raise due to the higher proportion of elderly in the west...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-018-0815-3

    authors: Lesyuk W,Kriza C,Kolominsky-Rabas P

    更新日期:2018-05-02 00:00:00

  • Value of the fT3/fT4 ratio and its combination with the GRACE risk score in predicting the prognosis in euthyroid patients with acute myocardial infarction undergoing percutaneous coronary intervention: a prospective cohort study.

    abstract:BACKGROUND:Thyroid hormones deeply influence the cardiovascular system; however, the association between the fT3/fT4 ratio and the clinical outcome in euthyroid patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) is not well defined. Therefore, the present study aimed to ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-018-0916-z

    authors: Yu T,Tian C,Song J,He D,Wu J,Wen Z,Sun Z,Sun Z

    更新日期:2018-09-10 00:00:00

  • Early changes in ambulatory electrocardiography after transcatheter closure in patients with atrial septal defect and factors affecting heart rate variability.

    abstract:BACKGROUND:Factors affecting heart rate variability (HRV) in patients with atrial septal defect (ASD) have not been clarified. This study sought to identify those factors and establish a preliminary risk model. METHODS:A total of 154 patients with ASD who underwent transcatheter closure and met the study requirements ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01699-4

    authors: Su Z,Cao Q,Zhang H,Sun W,Zhang H,Sheng Y,Yang R,Kong X

    更新日期:2020-09-11 00:00:00

  • Comparison of morphometry and ventricular function of healthy and smoking young people.

    abstract:BACKGROUND:Tobacco smoke is one of the most significant risk factors for cardiovascular diseases and damages in the myocardial tissue directly. Cardiac magnetic resonance (CMR) has been used and is a promising tool to evaluate morphometry and cardiac function in humans. The objective of this study was to evaluate assoc...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01372-w

    authors: Batista ANR,Garcia T,Franco EAT,Azevedo PS,Barbosa MF,Zornoff LAM,Minicucci MF,de Paiva SAR,Zucchi JW,de Godoy I,Tanni SE

    更新日期:2020-02-06 00:00:00

  • Profile and predictor of health-related quality of life among hypertensive patients in south-western Nigeria.

    abstract:BACKGROUND:The health-related quality of life (HRQOL) of hypertensives may be influenced by blood pressure, adverse effects of drugs used to treat hypertension, or other factors, such as the labelling effect, or beliefs and attitudes about illness and treatment. There is paucity of information on the determinants of HR...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-9-25

    authors: Ogunlana MO,Adedokun B,Dairo MD,Odunaiya NA

    更新日期:2009-06-17 00:00:00

  • ACE gene insertion/deletion polymorphism has a mild influence on the acute development of left ventricular dysfunction in patients with ST elevation myocardial infarction treated with primary PCI.

    abstract:BACKGROUND:We evaluated the associations among angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism, ACE activity and post-myocardial infarction (MI) left ventricular dysfunction and acute heart failure (AHF) early after presentation with MI with ST-segment elevation (STEMI). METHODS:A total ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-10-60

    authors: Parenica J,Goldbergova MP,Kala P,Jarkovsky J,Poloczek M,Manousek J,Prymusova K,Kubkova L,Tomcikova D,Toman O,Tesak M,Tomandl J,Vasku A,Spinar J

    更新日期:2010-12-17 00:00:00

  • Association between coronary dominance and acute inferior myocardial infarction: a matched, case-control study.

    abstract:BACKGROUND:Previous studies have found a connection between left coronary artery dominance and worse prognoses in patient with acute coronary syndrome, which remains a predominant cause of morbidity and mortality globally. The aim of this study was to investigate whether coronary dominance is associated with the incide...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-019-1007-5

    authors: Wang L,Li J,Gao Y,Li R,Zhang J,Su D,Wang T,Yang G,Wang X

    更新日期:2019-02-04 00:00:00

  • Left ventricular diastolic dysfunction in nonhuman primate model of dysmetabolism and diabetes.

    abstract:BACKGROUND:Diabetes is one of the major risk factors for cardiomyopathy and heart failure with reduced ejection fraction (EF) and highly associated with left ventricular (LV) dysfunction in human. This study aimed 1) to noninvasively assess cardiac function using echocardiography; 2) to test the hypothesis that like di...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-015-0133-y

    authors: Gu H,Liu Y,Mei S,Wang B,Sun G,Wang X,Xiao Y,Staup M,Gregoire FM,Chng K,Wang YJ

    更新日期:2015-10-30 00:00:00

  • Swallow syncope: a case report and review of literature.

    abstract:BACKGROUND:Swallow or deglutition syncope is an unusual type of neurally-mediated syncope associated with life-threatening bradyarrhythmia and hypotension. It is a difficult condition to diagnose with commonly delayed diagnosis and management. There is lack of review articles that elucidate the basic demographics, clin...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-019-1174-4

    authors: Siew KSW,Tan MP,Hilmi IN,Loch A

    更新日期:2019-08-07 00:00:00

  • Living with hypertrophic cardiomyopathy and an implantable defibrillator.

    abstract:BACKGROUND:ICDs efficiently terminate life-threatening arrhythmias, but complications occur during long-term follow-up. Patients' own perspective is largely unknown. The aim of the study was to describe experiences of hypertrophic cardiomyopathy (HCM) patients with implantable defibrillators (ICDs). METHODS:We analyze...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-017-0553-y

    authors: Magnusson P,Jonsson J,Mörner S,Fredriksson L

    更新日期:2017-05-10 00:00:00

  • Effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on cardiovascular events in patients with heart failure: a meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Heart failure (HF) remains a significant cause of morbidity and mortality. Multiple trials over the past several years have examined the effects of both angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) in the treatment of left ventricular dysfunction, both acutely ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12872-017-0686-z

    authors: Tai C,Gan T,Zou L,Sun Y,Zhang Y,Chen W,Li J,Zhang J,Xu Y,Lu H,Xu D

    更新日期:2017-10-05 00:00:00

  • Atherosclerosis profile and incidence of cardiovascular events: a population-based survey.

    abstract:BACKGROUND:Atherosclerosis is a chronic progressive disease often presenting as clinical cardiovascular disease (CVD) events. This study evaluated the characteristics of individuals with a diagnosis of atherosclerosis and estimated the incidence of CVD events to assist in the early identification of high-risk individua...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-9-46

    authors: Robinson JG,Fox KM,Bullano MF,Grandy S,SHIELD Study Group.

    更新日期:2009-09-15 00:00:00

  • Role of peroxisome proliferators-activated receptor-gamma in advanced glycation end product-mediated functional loss of voltage-gated potassium channel in rat coronary arteries.

    abstract:BACKGROUND:High blood glucose impairs voltage-gated K+ (Kv) channel-mediated vasodilation in rat coronary artery smooth muscle cells (CSMCs) via oxidative stress. Advanced glycation end product (AGE) and receptor for AGE (RAGE) axis has been found to impair coronary dilation by reducing Kv channel activity in diabetic ...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-020-01613-y

    authors: Gao S,Hua B,Liu Q,Liu H,Li W,Li H

    更新日期:2020-07-14 00:00:00

  • Distal transradial access: a review of the feasibility and safety in cardiovascular angiography and intervention.

    abstract:BACKGROUND:Transradial access (TRA) has been considered as the default choice in cardiac catheterization. Although infrequent, vascular complications of this approach remain. Recently, the distal transradial approach (dTRA) in cardiac catheterization was reported by interventionalists. METHODS:We retrieved the relevan...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,评审

    doi:10.1186/s12872-020-01625-8

    authors: Cai G,Huang H,Li F,Shi G,Yu X,Yu L

    更新日期:2020-08-05 00:00:00

  • The characteristics of two LDL-cholesterol level reduction treatment strategies, "treat-to-target" and "percent reduction": an observational study without intervention.

    abstract:BACKGROUND:The 2014 ACC/AHA guidelines redefined the strategy for LDL-cholesterol (LDL-C) treatment. According to data from evidence-based studies, the basis for earlier therapeutic recommendations for LDL-C target levels (2.6 and 1.8 mmol/L) may be disputed, and only the data for the percent LDL-C reduction are object...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-019-1038-y

    authors: Császár A

    更新日期:2019-03-11 00:00:00

  • Ability of ambulatory ECG-based T-wave alternans to modify risk assessment of cardiac events: a systematic review.

    abstract:BACKGROUND:Exercise-based spectral T-wave alternans (TWA) has been proposed as a noninvasive tool-identifying patients at risk of sudden cardiac death (SCD) and cardiac mortality. Prior studies have indicated that ambulatory electrocardiogram (AECG)-based TWA is an important alternative platform to exercise for risk st...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1186/1471-2261-14-198

    authors: Quan XQ,Zhou HL,Ruan L,Lv JG,Yao JH,Yao F,Huang K,Zhang CT

    更新日期:2014-12-20 00:00:00

  • The relationship between mitral annular systolic velocity and ejection fraction in patients with preserved global systolic function of the left ventricle.

    abstract:BACKGROUND:The aim of the study was to investigate the relationship between the ejection fraction (EF) and the mitral annular systolic velocity (Sm) in patients with preserved left ventricular systolic function (EF>55%). The study task was to evaluate whether the assessment of Sm(avg) can be used as an alternative to t...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2261-13-92

    authors: Daskalov IR,Daskalova IK,Demirevska LD,Atzev BG

    更新日期:2013-10-26 00:00:00

  • Left ventricular non-compaction: clinical features and cardiovascular magnetic resonance imaging.

    abstract:BACKGROUND:It is apparent that despite lack of family history, patients with the morphological characteristics of left ventricular non-compaction develop arrhythmias, thrombo-embolism and left ventricular dysfunction. METHODS:Forty two patients, aged 48.7 +/- 2.3 yrs (mean +/- SEM) underwent cardiovascular magnetic re...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-9-37

    authors: Yousef ZR,Foley PW,Khadjooi K,Chalil S,Sandman H,Mohammed NU,Leyva F

    更新日期:2009-08-09 00:00:00

  • Effects of betel nut on cardiovascular risk factors in a rat model.

    abstract:BACKGROUND:Areca nut (commonly known as betel nut) chewing has been shown to be associated with metabolic syndrome and cardiovascular disease (CVD). The mechanism by which betel nut ingestion could lead to development of CVD is not precisely known; however, dyslipidemia, hyperhomocysteinemia, hypertriglyceridemia and i...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-12-94

    authors: Iqbal MP,Mehboobali N,Haider G,Pervez S,Azam I

    更新日期:2012-10-24 00:00:00

  • A genetic variant c.553G > T (rs2075291) in the apolipoprotein A5 gene is associated with altered triglycerides levels in coronary artery disease (CAD) patients with lipid lowering drug.

    abstract:BACKGROUND:Elevated plasma triglycerides (TGs) are widely used as a major cardiovascular risk predictor and are thought to play an important role in the progression of coronary heart disease (CHD). It has been demonstrated that lipid lowering was associated with lower mortality in patients with CHD. The present study t...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/s12872-018-0965-3

    authors: Bogari NM,Aljohani A,Amin AA,Al-Allaf FA,Dannoun A,Taher MM,Elsayed A,Rednah DI,Elkhatee O,Porqueddu M,Alamanni F,Khogeer SAA,Fawzy A

    更新日期:2019-01-03 00:00:00

  • A common genetic factor underlies hypertension and other cardiovascular disorders.

    abstract:BACKGROUND:Certain conditions characterised by blood vessel occlusion or vascular spasm have been found to cluster together in epidemiological studies. However the biological causes for these associations remain controversial. This study used a classical twin design to examine whether these conditions are linked throug...

    journal_title:BMC cardiovascular disorders

    pub_type: 杂志文章

    doi:10.1186/1471-2261-4-20

    authors: Williams FM,Cherkas LF,Spector TD,MacGregor AJ

    更新日期:2004-11-01 00:00:00