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Applicability of the ankle-brachial-index measurement as screening device for high cardiovascular risk: an observational study.

Abstract：

BACKGROUND:Screening with ankle-brachial index (ABI) measurement could be clinically relevant to avoid cardiovascular events in subjects with asymptomatic atherosclerosis. To assess the practical impact of guidelines regarding the use of ABI as a screening tool in general practice, the corresponding number needed to screen, including the required time investment, and the feasibility of ABI performance, was assessed. METHODS:An observational study was performed in the setting of 955 general practices in the Netherlands. Overall, 13,038 subjects of ≥55 years presenting with symptoms of intermittent claudication and/or presenting with ≥ one vascular risk factor were included. Several guidelines recommend the ABI as an additional measurement in selected populations for risk assessment for cardiovascular morbidity. RESULTS:Screening of the overall population of ≥50 years results in ≈ 862 subjects per general practice who should be screened, resulting in a time-requirement of approximately 6 weeks of full time work. Using an existing clinical prediction model, 247 patients per general practice should be screened for PAD by ABI measurement. CONCLUSION:Screening the entire population of ≥50 years will in our opinion not be feasible in general practice. A more rationale and efficient approach might be screening of subsets of the population of ≥55 years based on a clinical prediction model.

journal_name

BMC Cardiovasc Disord

journal_title

BMC cardiovascular disorders

authors

Bendermacher BL,Teijink JA,Willigendael EM,Bartelink ML,Peters RJ,Langenberg M,Büller HR,Prins MH

doi

10.1186/1471-2261-12-59

subject

Has Abstract

pub_date

2012-07-30 00:00:00

pages

59

issn

1471-2261

pii

1471-2261-12-59

journal_volume

12

pub_type

杂志文章

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